LOCUS       NM_001145191            4287 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens family with sequence similarity 200 member B
            (FAM200B), mRNA.
ACCESSION   NM_001145191 XR_017764 XR_017908 XR_040763
VERSION     NM_001145191.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4287)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC035074.1, AC114744.7 and BQ004196.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001145191.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DA377919.1, SRR1660803.144028.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000422728.3/ ENSP00000393017.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2144              BC035074.1         27-2170
            2145-3663           AC114744.7         67089-68607
            3664-4287           BQ004196.1         11-634              c
FEATURES             Location/Qualifiers
     source          1..4287
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p15.32"
     gene            1..4287
                     /gene="FAM200B"
                     /gene_synonym="C4orf53"
                     /note="family with sequence similarity 200 member B"
                     /db_xref="GeneID:285550"
                     /db_xref="HGNC:HGNC:27740"
     exon            1..75
                     /gene="FAM200B"
                     /gene_synonym="C4orf53"
                     /inference="alignment:Splign:2.1.0"
     exon            76..4287
                     /gene="FAM200B"
                     /gene_synonym="C4orf53"
                     /inference="alignment:Splign:2.1.0"
     CDS             818..2791
                     /gene="FAM200B"
                     /gene_synonym="C4orf53"
                     /note="Putative protein FAM200B"
                     /codon_start=1
                     /product="protein FAM200B"
                     /protein_id="NP_001138663.1"
                     /db_xref="CCDS:CCDS47028.1"
                     /db_xref="GeneID:285550"
                     /db_xref="HGNC:HGNC:27740"
                     /translation="MDHFFIKRKRNSEVKYTEACSSSSVESGIVNSDNIEKNTDSNLQ
                     TSTSFEPHFKKKKVSARRYNEDYLKYGFIKCEKPFENDRPQCVICNNILANESLKPSK
                     LKRHLETQHAELIDKPLEYFQRKKKDIKLSTQFLSCSTAVSEKALLSSYLVAYRVAKE
                     KIANTAAEKIILPACLDMVRTIFDDKSADKLKTIPNDNTVSLRICTIAEHLETMLITR
                     LQSGIDFAIQLDESTDIGSCTTLLVYVRYAWQDDFLEDFLCFLNLTSHLSGLDIFTEL
                     ERRIVGQYKLNWKNCKGITSDGTATMTGKHSRVIKKLLEVTNNGAVWNHCFIHREGLA
                     SREIPQNLMEVLKNAVKVVNFIKGSSLNSRLLETFCSEIGTNHTHLLYHTKIRWLSQG
                     KILSRVYELRNEIHFFLIEKKSHLASIFEDDTWVTKLAYLTDIFSILNELSLKLQGKN
                     SDVFQHVERIQGFRKTLLLWQVRLKSNRPSYYMFPRFLQHIEENIINENILKEIKLEI
                     LLHLTSLSQTFNHFFPEEKFETLRENSWVKDPFAFRHPESIIELNLVPEEENELLQLS
                     SSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVLLLLPFTTTSLCELGFSILTQLKTK
                     ERNGLNCAAVMRVALSSCVPDWNELMNRQAHPS"
     regulatory      2794..2799
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM200B"
                     /gene_synonym="C4orf53"
                     /note="hexamer: AATAAA"
     polyA_site      2812
                     /gene="FAM200B"
                     /gene_synonym="C4orf53"
                     /note="major polyA site"
     regulatory      4268..4273
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM200B"
                     /gene_synonym="C4orf53"
                     /note="hexamer: AATAAA"
     polyA_site      4287
                     /gene="FAM200B"
                     /gene_synonym="C4orf53"
                     /note="major polyA site"
ORIGIN      
        1 agaggcgcag ctctgctgga gagacctgag gcttgcagcg ctgggcccgg ccgggtcgct
       61 gcggctgggc tggaggtcaa ggatgcattc caggaaagtt ctataaaaat ataccatcaa
      121 ctccaacctg atatttgacc tagccatgga aaacctcatt ggctcctcac tggatcagac
      181 cataaaaatg atccaggaat gaaaatctaa gataaattcc caccacttca agatgttctt
      241 atacaagtca acagtctagc agatcagcca gtctctttca tcatcaagca gacatactca
      301 aggtaccaac acagcaaagg cacaaaatgt ctctatatca gtatttttca tggtatatgt
      361 gagacccatt agtgaggcat gaaatcaatt ctgtgagtca caatgaacat ttgtctaaaa
      421 aacaaaataa aatgtaaaat accaaagtgt tttgcatgaa tcctttgcct gaattgtgca
      481 cattgcaagg aatgctgagg tcaatttcaa tatgcgagag gggtatttga tggaggagat
      541 atgatgaata gaatgtatat tggctaagaa atggttttca gtcattgatt cctgggtgtc
      601 ttgcttgatt ttcataatag cacggttaat gttctatagt caagttttat attacaatta
      661 cttgcaacta gttgtgaagt ctgaaatatt cgattcaatt gcaaactttg agtgtagttt
      721 ttgaaaagat gttatttaga ctgtatattt ttttcttctt ttttgagtta gtgccaatta
      781 taacatttta atcaaactgg aacaaattgc tattaaaatg gatcatttct ttattaaaag
      841 aaagaggaat agtgaagtga aatatacaga agcatgttca agttcatctg ttgaatctgg
      901 aattgtgaat agtgacaata ttgagaaaaa tactgactcc aatctgcaaa cttcaacttc
      961 atttgagcca catttcaaaa agaaaaaagt aagtgcaaga cgttataatg aagattactt
     1021 aaaatatggc tttatcaaat gtgaaaaacc ctttgaaaat gacagacctc agtgtgttat
     1081 ttgtaataat attcttgcga atgaaagctt aaaaccttcg aaattaaaaa ggcacttaga
     1141 aactcagcat gctgaactta ttgataagcc tcttgaatat tttcaaagaa agaaaaaaga
     1201 cataaagtta tcaacacaat ttcttagttg ttctactgct gttagtgaga aagccttatt
     1261 atcatcatat ttagttgcat atcgtgtggc aaaagagaaa atagctaaca cagctgctga
     1321 aaaaattatt cttccagcat gtttggatat ggtgcgtaca atatttgatg ataaatcagc
     1381 tgataaatta aaaactatac ctaatgataa cacagtatct cttcgaattt gtactattgc
     1441 agaacattta gaaacaatgc ttattactcg tttacagtct ggtatagatt ttgcaatcca
     1501 gcttgatgaa agcactgata ttggaagctg cacaacactt ttagtttatg tcagatatgc
     1561 gtggcaagat gattttttgg aggatttttt gtgtttttta aatttaacct cacacctaag
     1621 tggattagat atttttacag aattagaaag gcgcatagtt ggccaatata aattaaactg
     1681 gaaaaactgt aaaggaatta caagtgatgg cacagcaacc atgactggaa aacatagcag
     1741 agtaattaaa aaattactag aagttactaa taatggtgct gtgtggaatc attgttttat
     1801 acatcgtgaa ggtttagcat ccagagaaat tccacagaat ctcatggagg tattgaaaaa
     1861 tgcagtgaaa gttgttaatt ttattaaagg aagctcattg aatagccggc ttcttgaaac
     1921 attttgttca gagattggaa ctaatcatac ccacttacta tatcatacca aaattcgttg
     1981 gttgtctcaa gggaaaatac taagcagggt ttatgagctc aggaatgaga ttcacttttt
     2041 tctcattgaa aaaaaatctc atttggcaag tatttttgaa gatgatactt gggtaacaaa
     2101 attggcatat ttaactgata tttttagcat tcttaatgaa ctgagtttaa aactacaggg
     2161 gaaaaacagt gatgtattcc aacatgttga acgtatccag ggatttcgaa agacattatt
     2221 gttatggcaa gtaagactta aaagtaatcg tcctagctat tacatgtttc caagattttt
     2281 gcagcatatt gaagagaata ttattaatga aaacattttg aaagaaataa aattagagat
     2341 attgttgcat ctcacttctc tgtctcaaac ttttaaccat ttctttccag aagaaaaatt
     2401 tgaaacatta agggaaaaca gttgggtaaa agatccattt gcttttcgac accctgaatc
     2461 aataattgag ctaaacttgg tgcctgaaga agagaatgaa ttattgcagc ttagttcttc
     2521 atatacattg aagaatgatt atgaaacctt aagtttatca gcattttgga tgaaggtaaa
     2581 ggaagacttt ccattgttaa gtagaaagag tgtcctgcta ttgctaccat tcacaacaac
     2641 tagtttgtgt gaactagggt tttccatctt aacgcagtta aaaacaaagg aaagaaatgg
     2701 gctgaattgt gcagcagtta tgcgggtagc attatcttcc tgtgttccag actggaatga
     2761 acttatgaac aggcaagcac acccatcata gtaaataaaa atcttaccta gcttttgtct
     2821 ttgtatttct tattttgtag tatttttcta tgttatattt aaatggtact ataatactgt
     2881 gatacttttg ttatgtttta atttttgtta tatttaataa aattatttta tgttcattga
     2941 acaaaaattt aatgaatttc tgttagaggc caggaactat tctagagaca tttgggatac
     3001 aaaagtgaac aaaacaggta attccctagt agagtttata tcctggcaag gagaaattga
     3061 caataaacct aataaataag gtttataata tttagaagct attaagtgct atggaaagag
     3121 tagtaagaag gaaggtcagg gaagtactgg ggaaccaaac catgaagggt tctgtagacc
     3181 attattgggc ctctggcttt tgtcagtgga ctagagaaca gttgaagggt ttaagcgaag
     3241 gagagaaatg atctgagcta ggttttaaaa gacactctgg tcactatttt aaattcttag
     3301 ggtaagtctg aattaaatgt tactttcccc tcactgggca tggtggctca gacctgtaat
     3361 ccccgcactt tggcaggcca tggcagaagg ctctgttgag cccaggagtt caagaccatc
     3421 ctgggcaaca tagtgagacc ttatttctac taaaaatatt ttaaaaataa gtcaggtgtg
     3481 gtggtgcaca cctatagtcc cagctactca ggaggctgtg gcaggagggt cgcttgacct
     3541 caggagtttg aagttgcagt catctatgat tgcaccactg cagtccagcc tgagcaacag
     3601 agtgaaaccc tgtctcgaga aaattaaatg ttacttccct aaaaaaacct tttctaacca
     3661 ccctagggta aatcctccat tattccttta tttctttgtt ttccttgtag tatataattt
     3721 gtaataattt tgattactga ttgtcattct gccaccctgg agtatataat ttttaattat
     3781 ctgattactg ttattcttcc atagtagggg aggtgatatc catttgcctg atacatagta
     3841 tgtgttcaat acacatttgc taaagaataa atgaatcaat aatacctaac atctctaatt
     3901 tgcagtcatt cccaagagta attattaaat atgtggcaaa tttctttgcc tttttacttt
     3961 taaaaatcta attttgacat aactgctgta accatccaga aacggcattg atgttgcttc
     4021 acgttgctga tgcttaagca atgtatattg tgtaatatac aatgtagtct tcaaactaat
     4081 ttcaacttct gcctttctgt gtactccctt atcccactgg gtgatattat ttggcatggt
     4141 cattgtcatt aaaatcatac aggatagtaa ttcctttcca tctgctacca tgcctagcct
     4201 tatttaattt ttcagatttt ctgttctatt gaaggtaatt gattttttct ttttttttaa
     4261 tgcttgaaat aaagtgttga aaaacaa
//
