LOCUS       NM_145111               2468 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens family with sequence similarity 200 member A
            (FAM200A), mRNA.
ACCESSION   NM_145111
VERSION     NM_145111.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2468)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2468)
  AUTHORS   Thompson,E.E., Kuttab-Boulos,H., Yang,L., Roe,B.A. and Di Rienzo,A.
  TITLE     Sequence diversity and haplotype structure at the human CYP3A
            cluster
  JOURNAL   Pharmacogenomics J 6 (2), 105-114 (2006)
   PUBMED   16314882
REFERENCE   3  (bases 1 to 2468)
  AUTHORS   Smit,A.F.
  TITLE     Interspersed repeats and other mementos of transposable elements in
            mammalian genomes
  JOURNAL   Curr Opin Genet Dev 9 (6), 657-663 (1999)
   PUBMED   10607616
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK290724.1 and BC040214.1.
            
            On Nov 22, 2018 this sequence version replaced NM_145111.3.
            
            Summary: This gene encodes a protein of unknown function. The
            protein is weakly similar to transposase-like proteins in human and
            mouse. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC040214.1, AK290724.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000449309.2/ ENSP00000411372.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-250               AK290724.1         21-270
            251-2468            BC040214.1         188-2405
FEATURES             Location/Qualifiers
     source          1..2468
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q22.1"
     gene            1..2468
                     /gene="FAM200A"
                     /gene_synonym="C7orf38"
                     /note="family with sequence similarity 200 member A"
                     /db_xref="GeneID:221786"
                     /db_xref="HGNC:HGNC:25401"
     exon            1..261
                     /gene="FAM200A"
                     /gene_synonym="C7orf38"
                     /inference="alignment:Splign:2.1.0"
     exon            262..2468
                     /gene="FAM200A"
                     /gene_synonym="C7orf38"
                     /inference="alignment:Splign:2.1.0"
     CDS             361..2082
                     /gene="FAM200A"
                     /gene_synonym="C7orf38"
                     /codon_start=1
                     /product="protein FAM200A"
                     /protein_id="NP_659802.1"
                     /db_xref="CCDS:CCDS5668.1"
                     /db_xref="GeneID:221786"
                     /db_xref="HGNC:HGNC:25401"
                     /translation="MTPESRDTTDLSPGGTQEMEGIVIVKVEEEDEEDHFQKERNKVE
                     SSPQVLSRSTTMNERALLSSYLVAYRVAKEKMAHTAAEKIILPACMDMVRTIFDDKSA
                     DKLRTIPLSDNTISRRICTIAKHLEAMLITRLQSGIDFAIQLDESTDIASCPTLLVYV
                     RYVWQDDFVEDLLCCLNLNSHITGLDLFTELENCLLGQYKLNWKHCKGISSDGTANMT
                     GKHSRLTEKLLEATHNNAVWNHCFIHREALVSKEISPSLMDVLKNAVKTVNFIKGSSL
                     NSRLLEIFCSEIGVNHTHLLFHTEVRWLSQGKVLSRVYELRNEIYIFLVEKQSHLANI
                     FEDDIWVTKLAYLSDIFGILNELSLKMQGKNNDIFQYLEHILGFQKTLLLWQARLKSN
                     RPSYYMFPTLLQHIEENIINEDCLKEIKLEILLHLTSLSQTFNYYFPEEKFESLKENI
                     WMKDPFAFQNPESIIELNLEPEEENELLQLSSSFTLKNYYKILSLSAFWIKIKDDFPL
                     LSRKSILLLLPFTTTYLCELGFSILTRLKTKKRNRLNSAPDMRVALSSCVPDWKELMN
                     RQAHPSH"
     regulatory      2444..2449
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM200A"
                     /gene_synonym="C7orf38"
                     /note="hexamer: AATAAA"
     polyA_site      2468
                     /gene="FAM200A"
                     /gene_synonym="C7orf38"
                     /note="major polyA site"
ORIGIN      
        1 gtgacgcttt ccctgggctc tgaaggccag ggggcttgga tgtgagtcta gtgctcctgg
       61 tccccaaagt cacaacccct tctatcccag catcccagac ttctccgggc ggggacagag
      121 ttggacgtgc atggctgtgt cctgcaatcc cctcgccacg accgcccggg acggagtgga
      181 agcgggtccg tgcccccgtt cctcgcgcca gcctcggcgg tggcaagcgc tgtcccccag
      241 cagaggtgtc cctggataca ggatagcaaa acctgatctc ataaaaccta ggtcacaaag
      301 gacagccctg caaaacagac cctatttgga tcaagtgagc cagttcctgg aacctgaata
      361 atgactcctg aatcaaggga tactacagat ttgtctccag ggggtaccca ggagatggaa
      421 ggcatcgtga tagtgaaggt ggaggaggaa gatgaagaag accattttca aaaggaaaga
      481 aacaaagtag agtcatcgcc acaagttctc agtcgctcta caactatgaa tgagagagcc
      541 ttattgtcat cgtatttagt tgcatataga gtggcaaaag agaaaatggc tcacacagcg
      601 gctgaaaaaa ttatccttcc agcatgtatg gacatggtac ggacaatttt tgatgacaaa
      661 tcagctgata aactaagaac tatacctctt agtgataata caatatctcg tcgaatctgt
      721 acgattgcaa aacatttgga agcaatgctt attacacggc tgcagtccgg tatagacttt
      781 gcaatccaac tcgatgagag cactgatatt gcaagttgtc ccacactctt ggtttatgtc
      841 agatatgtgt ggcaagatga ttttgtagag gatctcttat gttgtttaaa tttaaattca
      901 catataactg gattagattt atttactgaa ttagaaaact gccttcttgg tcagtataaa
      961 ttaaactgga aacattgtaa aggaatttca agtgatggaa cagcaaatat gaccggaaaa
     1021 cacagcagac ttactgaaaa attgttagaa gcaacccaca acaatgctgt ttggaatcac
     1081 tgttttattc atcgagaagc tttggtatcc aaagaaattt caccaagtct gatggatgta
     1141 ttgaaaaatg cagtgaaaac tgttaatttt attaaaggaa gctcactgaa tagccgactt
     1201 ctcgaaatat tttgttcaga gattggagtg aaccacaccc acttattgtt tcatacagaa
     1261 gttcgttggc tttctcaagg aaaagtattg agcagagtat atgaactcag gaacgagatt
     1321 tacatttttc tcgttgaaaa gcaatctcat ttggcaaata tttttgaaga cgacatttgg
     1381 gtaacaaaat tggcatattt aagtgatatt tttggcattc ttaatgaatt aagcctgaaa
     1441 atgcagggga aaaacaatga tatatttcag tatcttgaac atattctagg attccaaaag
     1501 acgttattat tgtggcaagc aagacttaaa agtaaccgcc ctagctacta tatgtttcca
     1561 acattattgc aacacatcga agagaacatt attaatgaag actgcttaaa agaaataaaa
     1621 ttagagatat tgttgcatct cacttctttg tctcaaactt ttaattatta ctttccggaa
     1681 gagaaatttg aatcattaaa ggaaaatatt tggatgaaag atccatttgc ttttcaaaac
     1741 ccagaatcaa taattgagtt aaacttggag cctgaagaag agaatgaatt attgcagctc
     1801 agttcatcat tcacactaaa gaattattat aagatattaa gtttatcagc attttggatt
     1861 aagattaaag atgactttcc actgctaagt aggaagagta tattgctgtt actaccattc
     1921 acaactacat atttgtgtga actaggattt tcaatcttga cacggttaaa aacaaagaag
     1981 agaaataggc tcaatagtgc accagatatg cgggtagcat tatcttcatg tgttcctgac
     2041 tggaaggaac ttatgaacag acaagcacac ccatcacatt aaatacaaac tttacaaaat
     2101 tctgtgtata gccaggtgtg gtggcttacg cctgtaatcc cagcagtggg agaccgaggt
     2161 gggcagatca cttgagttca agaccagcct ggccaacatg gtgaaacccc atctctacta
     2221 aaaatagaaa ccttagccag gcgtggtggc acatgcctgc agtcccagtt acttgggtgc
     2281 ctgaggcagg agaatctctt aaaccaggaa ggcagagatt gcagtgagct gagataatcc
     2341 cactgcattc cagcctgggc aacagcgtga gacttcatct caaaaaaaaa aaattgtatt
     2401 tgtactttta aagggatttt gcagtatgtt gtagttaaac gttaataaaa ttatatttgt
     2461 aattagga
//
