LOCUS       NM_152481               1194 bp    mRNA    linear   PRI 12-JUN-2024
DEFINITION  Homo sapiens family with sequence similarity 187 member B
            (FAM187B), mRNA.
ACCESSION   NM_152481
VERSION     NM_152481.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1194)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC002128.1.
            
            On Apr 15, 2021 this sequence version replaced NM_152481.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK098526.1, BC117459.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000324675.4/ ENSP00000323355.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-781               AC002128.1         9414-10194          c
            782-1194            AC002128.1         6255-6667           c
FEATURES             Location/Qualifiers
     source          1..1194
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.12"
     gene            1..1194
                     /gene="FAM187B"
                     /gene_synonym="TMEM162"
                     /note="family with sequence similarity 187 member B"
                     /db_xref="GeneID:148109"
                     /db_xref="HGNC:HGNC:26366"
     exon            1..781
                     /gene="FAM187B"
                     /gene_synonym="TMEM162"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..1169
                     /gene="FAM187B"
                     /gene_synonym="TMEM162"
                     /note="transmembrane protein 162; protein FAM187B"
                     /codon_start=1
                     /product="protein FAM187B precursor"
                     /protein_id="NP_689694.1"
                     /db_xref="CCDS:CCDS12448.1"
                     /db_xref="GeneID:148109"
                     /db_xref="HGNC:HGNC:26366"
                     /translation="MPPMLWLLLHFAAPALGFYFSISCPSGKQCQQALLSGNDILLYC
                     NSSGAHWYYLFTQGKKGRLTSLTNISNMEIMPEGSLLIKDPLPSQTGLYHCWNKNGRQ
                     VVQYEIDFQDVTTLHITHKDLGQRPLQNETLHLGSKQLIFTWWEPWQDCNRCEEPGEC
                     KRLGYRYIEEPLEEAMPCWLYLGEVLVWSSRLRPELQVEACHVQCTNNTQLRVDYVIF
                     DNFRLDEKTEFVWLDCPLGSMYRPVNWRANDTPLTWESQLSGQDFTTFLDPSTGGRQL
                     QVFQPAVYKCFVQQELVAQFKPAASLETLEAQWRENDAQWREARKALRGRADSVLKGL
                     KLVLLVVTVLALLGALLKCIHPSPGRRSTQVLVVK"
     exon            782..1194
                     /gene="FAM187B"
                     /gene_synonym="TMEM162"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1165..1170
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM187B"
                     /gene_synonym="TMEM162"
                     /note="hexamer: AATAAA"
     polyA_site      1194
                     /gene="FAM187B"
                     /gene_synonym="TMEM162"
                     /note="major polyA site"
ORIGIN      
        1 atgggtgacc tcacaatgtt cggggtggca ccagcccact gccacagccc cagtccacca
       61 tgccacccat gctgtggctg ctgctccact ttgctgcccc ggcactgggg ttctactttt
      121 ccatcagctg ccccagtggt aagcagtgcc aacaggccct actctcaggc aatgatattc
      181 tcctgtattg caactcctcg ggggcgcact ggtactattt attcacacaa ggcaagaagg
      241 gcaggctcac cagcctcacc aatatttcca atatggaaat aatgcccgag ggcagccttc
      301 tcattaaaga tccattgccc tcccagacgg gcctctacca ctgctggaac aagaatggcc
      361 gccaagtggt gcagtatgaa attgactttc aggatgtcac caccctgcat ataacacaca
      421 aggacctggg tcagaggccc ctgcagaacg agaccctgca tttgggcagc aaacagctca
      481 tttttacctg gtgggagccc tggcaggact gcaaccgctg tgaggagccg ggcgagtgta
      541 aacgcctggg gtaccgctac attgaggagc ctctggagga agccatgccc tgctggctct
      601 atctgggaga ggtgctggtg tggtctagcc gcttgcggcc tgagctgcag gtggaagcct
      661 gccacgtcca gtgcaccaat aacacacagt taagggtgga ttacgtcatt tttgacaact
      721 tcaggctcga tgagaagaca gaatttgtgt ggctcgactg tcccttagga tccatgtaca
      781 ggcccgtcaa ctggcgtgcc aacgacaccc ccctgacgtg ggagagccag ctctccggcc
      841 aggacttcac cacctttctg gacccctcca ccggcggcag gcagctgcag gttttccagc
      901 cggccgtcta caagtgcttc gtgcagcagg agctcgtggc ccagttcaaa cccgccgcca
      961 gtctggagac gctggaggct cagtggagag agaacgatgc ccagtggcgg gaggcaagga
     1021 aggccctgcg gggcagggcg gactccgtgc tcaaggggct gaagctggtg ctgctcgtgg
     1081 tcaccgtcct ggccctgctg ggggcgctgc tcaagtgcat ccacccttcc ccgggcagga
     1141 gaagcacaca ggtgctggtg gtgaaataaa gcgagccccc ggtgcacaag cgga
//
