LOCUS       NM_015688               6731 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens family with sequence similarity 184 member B
            (FAM184B), mRNA.
ACCESSION   NM_015688 XM_001717325 XM_039169 XM_940199
VERSION     NM_015688.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6731)
  AUTHORS   He,M., Xu,M., Zhang,B., Liang,J., Chen,P., Lee,J.Y., Johnson,T.A.,
            Li,H., Yang,X., Dai,J., Liang,L., Gui,L., Qi,Q., Huang,J., Li,Y.,
            Adair,L.S., Aung,T., Cai,Q., Cheng,C.Y., Cho,M.C., Cho,Y.S.,
            Chu,M., Cui,B., Gao,Y.T., Go,M.J., Gu,D., Gu,W., Guo,H., Hao,Y.,
            Hong,J., Hu,Z., Hu,Y., Huang,J., Hwang,J.Y., Ikram,M.K., Jin,G.,
            Kang,D.H., Khor,C.C., Kim,B.J., Kim,H.T., Kubo,M., Lee,J., Lee,J.,
            Lee,N.R., Li,R., Li,J., Liu,J., Longe,J., Lu,W., Lu,X., Miao,X.,
            Okada,Y., Ong,R.T., Qiu,G., Seielstad,M., Sim,X., Song,H.,
            Takeuchi,F., Tanaka,T., Taylor,P.R., Wang,L., Wang,W., Wang,Y.,
            Wu,C., Wu,Y., Xiang,Y.B., Yamamoto,K., Yang,H., Liao,M., Yokota,M.,
            Young,T., Zhang,X., Kato,N., Wang,Q.K., Zheng,W., Hu,F.B., Lin,D.,
            Shen,H., Teo,Y.Y., Mo,Z., Wong,T.Y., Lin,X., Mohlke,K.L., Ning,G.,
            Tsunoda,T., Han,B.G., Shu,X.O., Tai,E.S., Wu,T. and Qi,L.
  TITLE     Meta-analysis of genome-wide association studies of adult height in
            East Asians identifies 17 novel loci
  JOURNAL   Hum Mol Genet 24 (6), 1791-1800 (2015)
   PUBMED   25429064
REFERENCE   2  (bases 1 to 6731)
  AUTHORS   Deng,X., Sabino,E.C., Cunha-Neto,E., Ribeiro,A.L., Ianni,B.,
            Mady,C., Busch,M.P. and Seielstad,M.
  CONSRTM   REDSII Chagas Study Group from the NHLBI Retrovirus Epidemiology
            Donor Study-II Component International
  TITLE     Genome wide association study (GWAS) of Chagas cardiomyopathy in
            Trypanosoma cruzi seropositive subjects
  JOURNAL   PLoS One 8 (11), e79629 (2013)
   PUBMED   24324551
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC005768.17 and AC006160.9.
            
            On May 17, 2019 this sequence version replaced NM_015688.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803615.132278.1, AB033102.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2157437, SAMN03465404
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000265018.4/ ENSP00000265018.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-109               AC005768.17        106094-106202
            110-463             AC005768.17        106203-106556
            464-1216            AC005768.17        178071-178823
            1217-1352           AC005768.17        179931-180066
            1353-1492           AC005768.17        181824-181963
            1493-1699           AC005768.17        182509-182715
            1700-1810           AC006160.9         14502-14612
            1811-1918           AC006160.9         19383-19490
            1919-2016           AC006160.9         43255-43352
            2017-2146           AC006160.9         47827-47956
            2147-2359           AC006160.9         49352-49564
            2360-2513           AC006160.9         54931-55084
            2514-2668           AC006160.9         60123-60277
            2669-2841           AC006160.9         65686-65858
            2842-2988           AC006160.9         68518-68664
            2989-3106           AC006160.9         71269-71386
            3107-3211           AC006160.9         72801-72905
            3212-3411           AC006160.9         74026-74225
            3412-3964           AC006160.9         75289-75841
            3965-6731           AC006160.9         75842-78608
FEATURES             Location/Qualifiers
     source          1..6731
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p15.32-p15.31"
     gene            1..6731
                     /gene="FAM184B"
                     /note="family with sequence similarity 184 member B"
                     /db_xref="GeneID:27146"
                     /db_xref="HGNC:HGNC:29235"
                     /db_xref="MIM:619945"
     exon            1..463
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     CDS             323..3505
                     /gene="FAM184B"
                     /codon_start=1
                     /product="protein FAM184B"
                     /protein_id="NP_056503.1"
                     /db_xref="CCDS:CCDS47033.1"
                     /db_xref="GeneID:27146"
                     /db_xref="HGNC:HGNC:29235"
                     /db_xref="MIM:619945"
                     /translation="MASALNSKINPPGTCQGSKADGGAGWRMDCDPQMHVKMCKKIAQ
                     LTKVIYALNTRQDEAEASMEALREAHQEELQNAVAETKARLLQEQGCAEEEALLQRIQ
                     ALESALELQKRLTEEALAESASCRLETKERELRVEAEHAERVLTLSREMLELKADYER
                     RLQHLTSHEATPQGRLPQESPETKSEPGQGPEMQEVLLEVQRLRVENQQLSKDYARKA
                     EELQATYERENEAIRQAMQQSVSQALWQWQEKESDLRKNFQVQESALQAQVRKLEGDL
                     EHRGRKISDLKKYAQKLKERIQDLDVQLKEARQENSELKGTAKKLGEKLAVAKDRMML
                     QECRGTQQTDAMKTELVSENKVLREENDLEAGNLHPQQDQSCLKECPCMKGGTDMQTK
                     KEASAETEYMKQQYEEDLRKIKHQTEEEKKHLKDQLVKRLEDLVKKHTVEIKSVRSSV
                     EAERKKLQREVEAQLEEVRKKSEKEIKQLEEEKAALNVKLQNSLLEVLRLEEFIQQNK
                     TRPTGAEESPQELGRQHCSILETQDPCLKLDETSPRGEEYQDKLAAEEGTSSDEEERT
                     KVLLKEGSDPQPPLGSLLKEKTSKIQRLEEDWQSQKAKLQAQVSQMQQALEQCTSNYR
                     EDLQALKQLSDLEREKLQRELQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATE
                     ERLKKESSHSLQIQHQTHRLELQALEEKARQELQEERERMQAQQALLLESLRQELSEQ
                     QAACSGHQKDLEALQAELRALGRQQASSQCPGDSKDHIIATEERGGPGQAGSPPGAAG
                     QGSGEGCGLWEENAQLQDAVRRLRAEVEQHQQEAQKLRDQRRFLEETQQAQRAREVET
                     LRQEHRKEMQAMVADFSSAQAQLQARLAALEAELKDSGEKPGKGASRPEDLQLIGRLQ
                     TRLKEREDIIKQLTEERRFHYAAFPSAMSHRNRSFSFNPHPGYLTPSMKKKKVEDVPS
                     RVVSVPNLASYAKNFLSGDLSSRINAPPITTSPSLDPSPSCGRTYKPNQSTDAKTATR
                     TPDGETAQAKEVQQKQGSPHQEWFTKYFSF"
     exon            464..1216
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1352
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            1353..1492
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            1493..1699
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            1700..1810
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            1811..1918
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..2016
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            2017..2146
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            2147..2359
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            2360..2513
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            2514..2668
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            2669..2841
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            2842..2988
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            2989..3106
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            3107..3211
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            3212..3411
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     exon            3412..6731
                     /gene="FAM184B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5116..5121
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM184B"
                     /note="hexamer: AATAAA"
     polyA_site      5146
                     /gene="FAM184B"
                     /note="major polyA site"
ORIGIN      
        1 acacgaaacc tgcactggct ggggaactgc agactgatcg ccagcggcac gtgcggggcg
       61 ccgacgcctc gccgcagggt gcgggtgccc gcggagccag ccagccagag aaccagcagg
      121 agaggaaaaa gggtgggcgc gcgggtgggc ccgggaggcg gagaccttcg ggaagctggg
      181 gccacgcggc ggtgcaggcg acgggactgc agtgccacct ctcccgagaa acccacacgc
      241 tcgcacgccc gcgcgcgcac gcacgtgcac acggtgggca gggagaaaac gagagagtct
      301 gagtgctggg cgcgttttag cgatggcttc tgctctcaac agcaaaatta acccgcccgg
      361 cacttgccag ggctccaaag ccgacggtgg cgccggctgg agaatggact gtgatcccca
      421 gatgcacgtg aaaatgtgca agaagatcgc ccagctcacc aaggtgattt atgccctgaa
      481 cacccgccag gatgaggctg aggccagcat ggaggcgctg cgggaagcgc accaggagga
      541 gctccagaat gcggtggcag agaccaaggc caggctcctg caggaacagg gctgcgcaga
      601 ggaggaagcc cttctacagc gcatccaggc cctggagagc gccctggagc tgcaaaagag
      661 gctgacggag gaggcgctgg ctgagtcggc ctcgtgcagg ctggagacga aggagagaga
      721 gctgagggtg gaggcagagc acgccgagcg agtcctcacg ctctccaggg aaatgctgga
      781 gctcaaggct gactacgaga ggaggctcca gcacctgacg agccacgagg ctaccccgca
      841 gggccggctg ccccaggaga gccctgaaac caagtcggag ccaggccagg gcccggagat
      901 gcaggaggtc ctgctagagg tgcagcggct gcgagtggag aaccagcagc tgagcaagga
      961 ctacgcccgc aaggccgagg agctgcaggc cacctacgag agggaaaacg aggccatccg
     1021 gcaggccatg cagcagtcgg tgagccaggc cctgtggcag tggcaggaga aggagtcgga
     1081 cctccgcaag aacttccagg tccaggagtc agccctgcag gctcaggtcc ggaagctgga
     1141 aggagacctg gagcacagag gccgcaagat aagtgacctg aagaagtacg cccagaagct
     1201 gaaggagagg attcaggacc tggatgtgca gcttaaggag gctcgacagg agaattcaga
     1261 gttgaaaggc actgcaaaaa aacttgggga gaagctggct gttgccaaag acagaatgat
     1321 gctgcaggag tgtcgtggga cacagcagac agatgccatg aagactgagt tagtttcaga
     1381 gaacaaagtc ctgcgggaag agaatgactt ggaagccggc aatcttcatc ctcagcagga
     1441 tcaaagctgt ctcaaggagt gcccttgcat gaaaggaggc acagatatgc agaccaagaa
     1501 agaggcaagt gctgagacag aatatatgaa gcaacaatat gaagaagacc ttcgtaaaat
     1561 caaacatcag acagaagagg agaagaaaca tctcaaagac cagctagtga agcgactaga
     1621 agacttggta aagaagcaca ccgtggaaat caaatccgtt cgctcgtccg tggaggctga
     1681 aagaaagaaa ctgcagaggg aagtagaagc acagttggag gaagtgagga agaaatcaga
     1741 aaaggagata aagcagctgg aagaagagaa agcagccctc aatgtgaagc ttcagaattc
     1801 tctgcttgag gttttaaggc tggaagaatt tatccaacaa aataagacac gccccacagg
     1861 agctgaggaa agtccccagg aattaggccg ccagcactgc agcattctgg agacccagga
     1921 tccatgcttg aagctggatg aaacttcgcc gagaggagag gagtatcaag ataagttagc
     1981 agctgaagaa ggaaccagca gtgatgaaga agaaaggacc aaagtgcttc tcaaggaggg
     2041 aagtgaccca caacctccac tgggctcttt gttgaaggag aaaacatcca aaatccagcg
     2101 tctagaggag gactggcaaa gccagaaggc caaattgcaa gcccaggtct cacagatgca
     2161 gcaggctctg gagcagtgca ccagcaacta cagggaggac ctgcaggcac tcaagcagct
     2221 ctcggacctg gagagggaga agctgcagcg tgagctccag gagaccactc agcagaacca
     2281 cgccatgaaa gcccagctcg aggcttccca ccagagagcc ctgcgcatgc tggagaaggc
     2341 cagacatcag gaactcaagg ccacagagga acgcttgaag aaggaatcca gccacagcct
     2401 ccagatccaa caccagacac accgactgga gctccaggcc ttggaggaaa aggccaggca
     2461 agagctgcag gaggagcgtg agaggatgca ggcacagcag gccctgctgc tagagtcgct
     2521 cagacaggag ctgtcggagc agcaagctgc ctgttctggg caccagaagg acttggaggc
     2581 actgcaggcc gagctgaggg ctctgggcag acagcaagcc agcagccagt gtccaggaga
     2641 cagcaaggat cacataatcg ccacagagga gcggggcggc ccgggccagg ccggctcccc
     2701 accgggcgct gctgggcagg gttccggcga gggatgcggg ctctgggagg agaacgcgca
     2761 gctccaggac gcggtgcggc ggctgcgcgc ggaggtggag cagcatcagc aggaggcgca
     2821 gaagctccga gaccagcgca ggttcctgga ggagactcag caagcccagc gggccaggga
     2881 ggtggagaca ctgcgccagg aacaccggaa ggagatgcag gccatggtgg cagatttcag
     2941 tagtgcccag gcccagctcc aggcccggct ggctgccctg gaagccgaac tgaaagattc
     3001 cggagagaag ccagggaagg gagcgtccag gcccgaggac cttcagctca ttggccgcct
     3061 gcagacccgc ctgaaggaga gagaggacat catcaagcag ctcacggaag agagaagatt
     3121 tcactacgca gcattcccca gtgccatgtc ccaccggaat cggtctttct ctttcaatcc
     3181 tcacccggga tatttgaccc cttccatgaa gaaaaagaag gtggaggacg tgcccagccg
     3241 cgtggtcagc gtgccgaacc tcgcctccta tgcaaagaac tttctgagtg gcgatctgag
     3301 ttccaggatt aatgcccctc caataactac atcacccagc ttggacccaa gccccagctg
     3361 tggccggacc tacaaaccca accagtctac agatgcaaaa actgccacaa ggaccccaga
     3421 tggtgaaacg gcccaagcca aagaagtcca gcagaaacag ggctctccgc accaggaatg
     3481 gttcaccaag tacttttctt tctaagctaa cctttgggat acatcacaga ggatacttga
     3541 aaaacattta ttttaaatca tccgattgaa ggaatgaact aacaccaacc aaccaaataa
     3601 tatgcttatg atttatatat gatagctaaa acaaattttg gcgttaacac ttcatactgt
     3661 tctgccaggc acagcagctc acgcctgtaa tcccatcact ttgggaggct gaggcagatg
     3721 gactgcttga gtccaggaat ttgagaccag cctggccaat atggtgaaac cccatctcta
     3781 caaaatatac aaaaattagc caggcatggt ggcgtgtgcc tgtggtccca ggtacttggg
     3841 ggactgaggc gggaggatca cttgaaccta ggaggcagag gttgcagtga gccaagttcg
     3901 aactcctgca ttccaaccag cctgggtgac agagggagac cctgtctcca aaaaaaaaaa
     3961 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaattgacat taaaccagtg ttattaaaag
     4021 tcatctatag gaaaatgtta ttagcgttac taatgaccca taccttgtat ttctagtgtc
     4081 cataacatca tactccattt tgtggaacat cagactttgt gatttccatg atctatttca
     4141 aaagtggttg tacttgtcct taggatgcta gtcaactcca ctggaaagct gtttctatgt
     4201 aaaatgatgc aattccaaaa tgcacatcta acctcaatag gaagacaaat aacagttaaa
     4261 caggaaagcc aactaaaaac aaaccaaacc taccagaaat ggatggtagc atgcttggac
     4321 tgaatacttt cacttccttg gtctaagaca agcagcagat tatagatggg ataacaccca
     4381 cctctaaaag ggctttgcaa ggattaagca agataacata aattaacatg aattggaatt
     4441 aagtaccaca aggtttttct gtaaataacc aatcctagcc cagttatagg tctcagtgta
     4501 atgaccatag tgccaacatg atcacttgtg aaggtctcta gattatctgt tctttgaagt
     4561 caaagatctt ctagactggg cacatggctc atgcctgtaa tcccaacact ttgggaggct
     4621 gagatgggag gagagcttga ggccaggaat ttgagaccag cctgggcaac acagcgagac
     4681 ctccatctct acaaaaaaat aattagccca aagaaaaccc agctacttgg aagtctgagg
     4741 taggacagca tgagcccaag agttcgagac cagcctgggc aagatagtga gatcccatct
     4801 ctacagatta aaaaaatata tatatatatc ccctgaacct ctggtctttg ggtttgagcc
     4861 atttgcctca tggtgtgttg cttcttcact gcatgaattc ccagtgggtt aaaggaaccg
     4921 caatggctgt tcacggtgct gaccttgctc tcagtccaca ctgatttgtc ttaccttctg
     4981 acagagcaat gtgatttgac aagactcaat aacaactttt agggggcaaa atattttttc
     5041 agtctttggt gctggcccag aaggtggccc acaaaccaat gttaattcta tgcattgtca
     5101 aatctttgct ctttgaataa aactttgaat aactgggcaa taaaaatggt tgacttgtat
     5161 tgattttcca cagaaaggta aaattagatg aagacagctt agaaatagaa agttcagttc
     5221 acattaacct caatcacacc atcttaaaaa aaaaaaagct gattacatat aactgtcaaa
     5281 cttacgtatt aaaggtaaat ttactgccta atcaaaacga ggctccaatg catttttaaa
     5341 tgcaaacaaa cacttgtcac catacattaa cacaccatac tgtttttcac taccaaatat
     5401 tttttgtgag tttcccgctt agagtgtctt agttcgttca ggctgctcta acaaaatatc
     5461 ttacttatac tggataattt ataaacaata gaaatatgtc actcacagtc ctagaggcta
     5521 agtccaagat caaggcacca gcagatatgg agtctgggga gggcccattc ttcagaaatg
     5581 ggtgcctgct acgtgtcctt acatggtgga agaggcaaga gcgcctccct gagcctcttt
     5641 tgtaagggta cttatcctac tcatgagggt gaagccctca tgactccatt gcttcccaaa
     5701 agccccacct cttaatacta ttacattgac attaggttcc aacatatgaa ttttggaagg
     5761 gacatcaaca ttcaggacat agcagtgaac cctgtaggac tgctctttat tttgtgcttt
     5821 caaaaagact acatacaggt ggttctattt ttgtgtgttg aaacactttc ccaggctgca
     5881 ctttgcattt ctgtccttaa actcagcatg atccctgggc aaggagaaaa ttttactagt
     5941 tgagatcgta cataggtttt gactcctttc ttgctgcagg tgactgaaaa gatctttcag
     6001 tcttaaattt ctaaattcta ccctgcaatg attatatctt tgttaacaaa atctttgcat
     6061 gcttccataa ttttttattg aggccatatg ccttgggtat tgaagtaagg catttaagga
     6121 cacaaactta agctttttgt ttgttattac caaactgcca ttcagaaagt ttctaacaat
     6181 ttacaccctt accagcagta aatgaaccta ctgtgcccta acactattga caaagaaata
     6241 caatttgata gataaaacat tctattttag tttgcataat gattccatca atctctcaac
     6301 agcagagcgg tctagagatg acagtgatgg cgtagaggtg acagtgaaga tgaagagaaa
     6361 ttatccaatt cgggattaag ttaagagaga gaaaaaaaca gtatttaatg gtaaatctct
     6421 tcaggctgta ttatgacagg ggtggaagag ttaatatgtt cctgcagcaa aactgaaagg
     6481 aatactatct gttccacatg aaagcaaact gttttgtaat tggggtaggt aaaaatggat
     6541 tcacccagtc aatggctgca caccacatac ctgagccctt aactgctcta acactgatgt
     6601 aatatccaac ccaacatttg tgattgaggc tacttggtta atttttctcc aggatccatc
     6661 tggattctgc agatgaggct ggcaaattaa atggaactat gatagggacc atcttactgt
     6721 atctgtcaga t
//
