LOCUS       NM_001394345            1677 bp    mRNA    linear   PRI 05-AUG-2024
DEFINITION  Homo sapiens family with sequence similarity 177 member B
            (FAM177B), mRNA.
ACCESSION   NM_001394345 XM_017001280
VERSION     NM_001394345.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1677)
  AUTHORS   Need,A.C., Attix,D.K., McEvoy,J.M., Cirulli,E.T., Linney,K.L.,
            Hunt,P., Ge,D., Heinzen,E.L., Maia,J.M., Shianna,K.V., Weale,M.E.,
            Cherkas,L.F., Clement,G., Spector,T.D., Gibson,G. and
            Goldstein,D.B.
  TITLE     A genome-wide study of common SNPs and CNVs in cognitive
            performance in the CANTAB
  JOURNAL   Hum Mol Genet 18 (23), 4650-4661 (2009)
   PUBMED   19734545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL392172.9.
            
            On Apr 15, 2021 this sequence version replaced XM_017001280.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074969.332139.1,
                                           SRR11853565.2880.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000445590.4/ ENSP00000414451.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-121               AL392172.9         49519-49639
            122-239             AL392172.9         50221-50338
            240-428             AL392172.9         58848-59036
            429-495             AL392172.9         59332-59398
            496-593             AL392172.9         61782-61879
            594-1677            AL392172.9         62238-63321
FEATURES             Location/Qualifiers
     source          1..1677
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q41"
     gene            1..1677
                     /gene="FAM177B"
                     /note="family with sequence similarity 177 member B"
                     /db_xref="GeneID:400823"
                     /db_xref="HGNC:HGNC:34395"
     exon            1..121
                     /gene="FAM177B"
                     /inference="alignment:Splign:2.1.0"
     exon            122..239
                     /gene="FAM177B"
                     /inference="alignment:Splign:2.1.0"
     exon            240..428
                     /gene="FAM177B"
                     /inference="alignment:Splign:2.1.0"
     CDS             255..731
                     /gene="FAM177B"
                     /codon_start=1
                     /product="protein FAM177B"
                     /protein_id="NP_001381274.1"
                     /db_xref="CCDS:CCDS1535.2"
                     /db_xref="GeneID:400823"
                     /db_xref="HGNC:HGNC:34395"
                     /translation="MEIDGFQQLDLEKSVPSKKTTPKRIIHFVDGDIMEEYSTEEEEE
                     EEKEEQSTNSTLDPSKLSWGPYLRFWAGRIASTSFSTCEFLGGRFAVFFGLTQPKYQY
                     VLNEFYRIQNKKSDNKSERRGSKAQAAEVPNEKCHLEAGVQEYGTIQQDVTEAIPQ"
     exon            429..495
                     /gene="FAM177B"
                     /inference="alignment:Splign:2.1.0"
     exon            496..593
                     /gene="FAM177B"
                     /inference="alignment:Splign:2.1.0"
     exon            594..1677
                     /gene="FAM177B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1152..1157
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM177B"
                     /note="hexamer: AATAAA"
     polyA_site      1175
                     /gene="FAM177B"
     regulatory      1657..1662
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM177B"
                     /note="hexamer: AATAAT"
     polyA_site      1677
                     /gene="FAM177B"
                     /note="major polyA site"
ORIGIN      
        1 atcatagggg cagaagatac agcagtgaac ataacaggta aaaccctccc cctctgccaa
       61 ggggcaggac agggaggaaa gggaagacag agacaggtgg aatatggagt gttcagtgtt
      121 gatttgatgt gaggtgtgat taaagaagaa ccaagaatga ctttagtgtt gttggcctga
      181 gcaactggaa gaacagagtt gccatttatt gagatgagaa ggctgccaga agagtagagt
      241 tgttttgttt cattatggag attgacggtt tccagcagtt agacctagag aagagtgtac
      301 cttccaaaaa gactactcct aaaaggatta tccattttgt tgacggagac atcatggaag
      361 aatatagcac agaggaggag gaggaagagg aaaaggagga gcagagcaca aattcaacac
      421 ttgacccttc taaactttcc tgggggccct acctacgatt ttgggcagga cgaatagcaa
      481 gcacctcatt ttctacatgt gaattccttg gtggaagatt tgctgtcttc tttggtctta
      541 ctcaacccaa atatcagtat gtgttaaacg agttctatag gatacaaaac aagaaaagtg
      601 acaacaaaag tgaaaggaga ggatcaaagg cccaggcagc tgaggttcct aatgaaaagt
      661 gtcacttgga ggctggggtc caagagtatg gaaccataca acaggatgtg acagaggcca
      721 ttcctcagtg aagcacctca tccagggagg gtctggtggc agatcctagc tcatgatggc
      781 agcaaagact gcagtttccc tggatctgtt ccttggccat tgattaccat ggcaacaaca
      841 ccagaggtag cacttctgag ccagatctga tcctaatctc tgtgtgactt agtctcaagc
      901 atccaggaat tacaagcaat aatgagagta attttggaca ctttctcaga ataatttcta
      961 tattcaagcc accccacctc aactccaccc ctgtgataca agtcccatga gtactgacat
     1021 ttgcacagta gcataaatgc cttaaggaac tttgggactg ggagtttttg gctgaaatcc
     1081 tctgtcatgg gacgagggta cagtaaagaa gctctattcc tcagaagaaa atttgggcac
     1141 cgcaaagtct aaataaatcc cctttcagga tttgatatag tgtgtacttc caacaaccat
     1201 cctggcgtag ttggggattg ttttacaata agtaaacatt gctaataact gtgttacaag
     1261 atcattatca agatctttaa gaattaggta catccctcca aattaaaaca attgataaat
     1321 aatataagct ctagaaaaaa atattaatgg attattttct tatttatttg tcaagaaatt
     1381 ttcaaaacct ggaaagatcg aacatggaaa tcattgttag ataacacagg gtgtgctggc
     1441 caaagtaact gtgatacatt aatagcaaaa aacaaaccaa aaaaaaaaaa aatgaaaaac
     1501 acagggcctg cagtagtaag acatgagttc cagtttcact tctcccattt actagttgtg
     1561 tgatttgaga tgtctagatt tctgagctcc agtctacttt gtaaaatatg ggtgacttga
     1621 ctttgcttgt tattgttata cagaattatg agaaataata atttattgtt gttttaa
//
