LOCUS       NM_017914                870 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens family with sequence similarity 174 member C
            (FAM174C), mRNA.
ACCESSION   NM_017914
VERSION     NM_017914.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 870)
  AUTHORS   Wang,X.R., Zhou,Y.B., Liu,F., Wang,K.S., Shen,Y., Liu,J.H. and
            Han,Z.G.
  TITLE     A novel recently evolved gene C19orf24 encodes a non-classical
            secreted protein
  JOURNAL   Cell Mol Biol Lett 11 (2), 161-170 (2006)
   PUBMED   16847563
  REMARK    GeneRIF: The isolation and characterization of a novel human
            non-classical secreted protein which is encoded by the hypothetical
            gene C19orf24 (chromosome 19 open reading frame 24), is reported.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX402818.2, BG333480.1 and BM675280.1.
            
            On Nov 22, 2018 this sequence version replaced NM_017914.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AL558482.3, SRR1163655.4691.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000409293.6/ ENSP00000386557.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-12                BX402818.2         10-21
            13-430              BG333480.1         2-419
            431-870             BM675280.1         34-473              c
FEATURES             Location/Qualifiers
     source          1..870
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.3"
     gene            1..870
                     /gene="FAM174C"
                     /gene_synonym="C19orf24"
                     /note="family with sequence similarity 174 member C"
                     /db_xref="GeneID:55009"
                     /db_xref="HGNC:HGNC:26073"
     exon            1..301
                     /gene="FAM174C"
                     /gene_synonym="C19orf24"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..419
                     /gene="FAM174C"
                     /gene_synonym="C19orf24"
                     /note="protein FAM174C"
                     /codon_start=1
                     /product="protein FAM174C precursor"
                     /protein_id="NP_060384.3"
                     /db_xref="CCDS:CCDS12060.2"
                     /db_xref="GeneID:55009"
                     /db_xref="HGNC:HGNC:26073"
                     /translation="MGPRVLQPPLLLLLLALLLAALPCGAEEASPLRPAQVTLSPPPA
                     VTNGSQPGAPHNSTHTRPPGASGSALTRSFYVILGFCGLTALYFLIRAFRLKKPQRRR
                     YGLLANTEDPTEMASLDSDEETVFESRNLR"
     exon            302..418
                     /gene="FAM174C"
                     /gene_synonym="C19orf24"
                     /inference="alignment:Splign:2.1.0"
     exon            419..870
                     /gene="FAM174C"
                     /gene_synonym="C19orf24"
                     /inference="alignment:Splign:2.1.0"
     regulatory      847..852
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM174C"
                     /gene_synonym="C19orf24"
                     /note="hexamer: AATAAA"
     polyA_site      870
                     /gene="FAM174C"
                     /gene_synonym="C19orf24"
                     /note="major polyA site"
ORIGIN      
        1 gccaccgctt ccgccgggcc atggggccgc gcgtgctgca gccgccgctg ctgctgctcc
       61 tgctggcgct gctgctggcg gcgctgccgt gcggtgccga agaggcctcg ccgctgcgcc
      121 ccgcgcaggt cacgttgtcg ccgccgccgg ccgtgacgaa cgggagccag ccgggcgcgc
      181 cacacaacag cacgcacacg cgtccgccgg gggcgtcggg ctcggcgctg acgcgctcct
      241 tctacgtgat cctgggcttc tgcggcctga ccgcgctcta cttcctgatc cgggcgttta
      301 ggttgaagaa gcctcagcgg aggcgatacg gcctcctcgc caacactgag gaccccacgg
      361 agatggcctc gctggacagc gacgaggaga cggtgtttga gtcccggaat ctgagatgat
      421 gctgagccag ggaggcggcc cttccagcag ccatgaggga aggacaggag atggggccca
      481 ccccagtgcc cagcaacccc ctgctccacc gctcattccc ctgctggccc cggggctggt
      541 ctcacccagt gccaacccga gagctccttt tggaacctgc acagcccgcc gacctgttgc
      601 cacctgcacc caccgctgga ccatgcagcc tcgcctcctg gatgctgtcc cagcctggcc
      661 gagggtccca ggtgaagact ggagggaccc caacagccac cgcccaggac gctgaggctc
      721 ccttgcctga ctgtgacttg tgcctctctc ctgcccccgt ggggacatgg cagcccagag
      781 ccaaggctgg gtgggcaggt gacccaagga acctttctgg gaacaccttc tcgccgggct
      841 gggaacaata aatgcagcca tgtctctgca
//
