LOCUS       NM_205548               1586 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens family with sequence similarity 151 member B
            (FAM151B), mRNA.
ACCESSION   NM_205548 XM_094565
VERSION     NM_205548.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Findlay,A.S., McKie,L., Keighren,M., Clementson-Mobbs,S.,
            Sanchez-Pulido,L., Wells,S., Cross,S.H. and Jackson,I.J.
  TITLE     Fam151b, the mouse homologue of C.elegans menorin gene, is
            essential for retinal function
  JOURNAL   Sci Rep 10 (1), 437 (2020)
   PUBMED   31949211
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  AUTHORS   Clark,H.F., Gurney,A.L., Abaya,E., Baker,K., Baldwin,D., Brush,J.,
            Chen,J., Chow,B., Chui,C., Crowley,C., Currell,B., Deuel,B.,
            Dowd,P., Eaton,D., Foster,J., Grimaldi,C., Gu,Q., Hass,P.E.,
            Heldens,S., Huang,A., Kim,H.S., Klimowski,L., Jin,Y., Johnson,S.,
            Lee,J., Lewis,L., Liao,D., Mark,M., Robbie,E., Sanchez,C.,
            Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V.,
            Stinson,J., Vagts,A., Vandlen,R., Watanabe,C., Wieand,D., Woods,K.,
            Xie,M.H., Yansura,D., Yi,S., Yu,G., Yuan,J., Zhang,M., Zhang,Z.,
            Goddard,A., Wood,W.I., Godowski,P. and Gray,A.
  TITLE     The secreted protein discovery initiative (SPDI), a large-scale
            effort to identify novel human secreted and transmembrane proteins:
            a bioinformatics assessment
  JOURNAL   Genome Res 13 (10), 2265-2270 (2003)
   PUBMED   12975309
  REMARK    Erratum:[Genome Res. 2003 Dec;13(12):2759]
REFERENCE   3  (bases 1 to 1586)
  AUTHORS   Soares,M.B., Bonaldo,M.F., Jelene,P., Su,L., Lawton,L. and
            Efstratiadis,A.
  TITLE     Construction and characterization of a normalized cDNA library
  JOURNAL   Proc Natl Acad Sci U S A 91 (20), 9228-9232 (1994)
   PUBMED   7937745
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC131563.1, AY358256.1 and T10044.1.
            
            On Nov 22, 2018 this sequence version replaced NM_205548.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY358256.1, BC131563.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA1970526
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000282226.5/ ENSP00000282226.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1161              BC131563.1         52-1212
            1162-1410           AY358256.1         1281-1529
            1411-1586           T10044.1           3-178               c
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q14.1"
     gene            1..1586
                     /gene="FAM151B"
                     /gene_synonym="UNQ9217"
                     /note="family with sequence similarity 151 member B"
                     /db_xref="GeneID:167555"
                     /db_xref="HGNC:HGNC:33716"
     exon            1..49
                     /gene="FAM151B"
                     /gene_synonym="UNQ9217"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..855
                     /gene="FAM151B"
                     /gene_synonym="UNQ9217"
                     /note="AASA9217"
                     /codon_start=1
                     /product="protein FAM151B"
                     /protein_id="NP_991111.2"
                     /db_xref="CCDS:CCDS4051.1"
                     /db_xref="GeneID:167555"
                     /db_xref="HGNC:HGNC:33716"
                     /translation="MAASAGGPGSWSENILEYFLRNSQITAEDGAEITWYHAANHKAQ
                     TNEALKSTAHMIEADVLLPSDGSEHSQPIMAHPPETNSDNTLQEWLTEVMKSNKGIKL
                     DFKSLAVVEPSMMLLENVKRHLKRPVWINADILPGPNGNSKVIDAKPFLDTVISFFPD
                     VTFSLGWTTGWHPEKVNEGYSWTMVKEMEYICNELSQPVTFPVRAALVRQSCSQLLWL
                     LKKSNRYSLTIWTGKNDNYSVEDLLYIRDHFDKKQVFYDILEPQNHEFKQAIGIKVNL
                     "
     exon            50..175
                     /gene="FAM151B"
                     /gene_synonym="UNQ9217"
                     /inference="alignment:Splign:2.1.0"
     exon            176..341
                     /gene="FAM151B"
                     /gene_synonym="UNQ9217"
                     /inference="alignment:Splign:2.1.0"
     exon            342..559
                     /gene="FAM151B"
                     /gene_synonym="UNQ9217"
                     /inference="alignment:Splign:2.1.0"
     exon            560..695
                     /gene="FAM151B"
                     /gene_synonym="UNQ9217"
                     /inference="alignment:Splign:2.1.0"
     exon            696..1586
                     /gene="FAM151B"
                     /gene_synonym="UNQ9217"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1472..1477
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM151B"
                     /gene_synonym="UNQ9217"
                     /note="hexamer: AATATA"
     polyA_site      1490
                     /gene="FAM151B"
                     /gene_synonym="UNQ9217"
                     /note="major polyA site"
     regulatory      1568..1573
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM151B"
                     /gene_synonym="UNQ9217"
                     /note="hexamer: AGTAAA"
     polyA_site      1586
                     /gene="FAM151B"
                     /gene_synonym="UNQ9217"
                     /note="major polyA site"
ORIGIN      
        1 gcgcggacgg cgggcgtcgt caccatggca gcatccgctg gaggcccagg atcttggagt
       61 gaaaatatac tggaatattt tctgagaaat agccagatta cagcagaaga cggtgctgag
      121 atcacctggt atcatgcagc taaccacaag gcacaaacaa atgaggcact gaaaagtact
      181 gctcacatga tagaggctga tgtccttctt ccaagtgatg gatcagaaca cagccagcca
      241 attatggccc atccccctga aacaaacagt gataatactc tacaggagtg gctgactgaa
      301 gttatgaaaa gcaataaagg catcaagctg gatttcaaaa gtctggcagt tgtagaacca
      361 tccatgatgc tcttggaaaa tgtgaagagg catctgaagc gtcctgtatg gattaatgcc
      421 gatattcttc ctggtccaaa tggaaatagc aaagtaatag atgcaaaacc atttttagac
      481 accgtgatat ccttctttcc agacgtgacg ttttccctgg gttggacaac aggatggcat
      541 cctgagaaag tcaatgaagg gtacagttgg acaatggtga aagagatgga atatatatgt
      601 aatgaactaa gtcagcctgt aacgttccct gtcagagcag cattagtcag gcagtcttgt
      661 tctcagttac tttggctgtt aaagaaatca aacaggtaca gcctgactat ttggactgga
      721 aaaaatgata actattccgt tgaagattta ctttacatta gagaccattt tgacaaaaaa
      781 caagttttct atgacatctt ggaaccacaa aaccatgaat ttaaacaagc cattggaatc
      841 aaagttaatc tctaagaaga agattctcaa ttatttcctg tgttttggtt tcataatcct
      901 tctctccatt ggtctgaatt aattaccata taaattatgg ttattgattg acgttccaag
      961 tcatctaatc aagaaacgtt tattgtatgc ttactctgtg ggcatatgtc cttataatag
     1021 tgcacttaca taaaagattt ggaaagaaga gatttattta cacacgtggc ctagtctaat
     1081 aataattcag gaaaatgata ctctgcaccc cttcataaaa atagttttga taaactaaag
     1141 atgattggca gaatccatat gtcataaaac aggtataaat cacatgtgct tggcacttgc
     1201 attacagaga ttatgaaaaa tatggtactc ttttcctttt tcctagaaaa ctggttattt
     1261 tagagataac aaaaaaggaa gagggctttt aaaatgtttt taattttcac aggggtcagc
     1321 agctgtctca tatcaagatc tattaatcca tttcctgaaa ctgtagatta aattagatag
     1381 atctagaatt tccatgtgat tgagaagcat gctagtggct aagtgttttt tttatatttc
     1441 ttatttctat agtatctgat ttatagtgga caatatactg ttggagagca gttttagtct
     1501 ttgttatgta tcatttgttt tccaagtttc ttactgccac caccttcatt caggtccttg
     1561 ttctactagt aaaactttat gaacta
//
