LOCUS       NM_182623               1720 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens family with sequence similarity 131 member C
            (FAM131C), mRNA.
ACCESSION   NM_182623 XM_938670
VERSION     NM_182623.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1720)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 1720)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 1720)
  AUTHORS   Need,A.C., Attix,D.K., McEvoy,J.M., Cirulli,E.T., Linney,K.L.,
            Hunt,P., Ge,D., Heinzen,E.L., Maia,J.M., Shianna,K.V., Weale,M.E.,
            Cherkas,L.F., Clement,G., Spector,T.D., Gibson,G. and
            Goldstein,D.B.
  TITLE     A genome-wide study of common SNPs and CNVs in cognitive
            performance in the CANTAB
  JOURNAL   Hum Mol Genet 18 (23), 4650-4661 (2009)
   PUBMED   19734545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL355994.11, AL529663.3, BC016848.1, BC037394.1, DA112406.1,
            BG751253.1 and AK094085.1.
            
            On Nov 23, 2018 this sequence version replaced NM_182623.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.35372.1, BC016848.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145774, SAMEA2145893
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000375662.5/ ENSP00000364814.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-19                AL355994.11        104861-104879       c
            20-25               AL529663.3         1-6
            26-74               BC016848.1         1-49
            75-424              BC037394.1         24-373
            425-477             DA112406.1         249-301
            478-576             BC016848.1         453-551
            577-608             AL355994.11        91149-91180         c
            609-751             BC016848.1         584-726
            752-852             BG751253.1         271-371
            853-1199            AK094085.1         723-1069
            1200-1631           AL355994.11        89086-89517         c
            1632-1720           BC037394.1         1581-1669
FEATURES             Location/Qualifiers
     source          1..1720
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.13"
     gene            1..1720
                     /gene="FAM131C"
                     /gene_synonym="C1orf117"
                     /note="family with sequence similarity 131 member C"
                     /db_xref="GeneID:348487"
                     /db_xref="HGNC:HGNC:26717"
     exon            1..231
                     /gene="FAM131C"
                     /gene_synonym="C1orf117"
                     /inference="alignment:Splign:2.1.0"
     CDS             210..1052
                     /gene="FAM131C"
                     /gene_synonym="C1orf117"
                     /codon_start=1
                     /product="protein FAM131C"
                     /protein_id="NP_872429.2"
                     /db_xref="CCDS:CCDS41270.1"
                     /db_xref="GeneID:348487"
                     /db_xref="HGNC:HGNC:26717"
                     /translation="MGSCVSRDLFTSAHKNCPMPQGADPLNPDLPSGRTPTVAPDCVI
                     GKDKQMDFCWDPWQRCFQTTNGYLSDSRSRPGNYNVAALATSSLVGVVQSIKDHITKP
                     TAMARGRVAHLIEWKGWSAQPAGWELSPAEDEHYCCLPDELREARFAAGVAEQFAITE
                     ATLSAWSSLDEEELHPENSPQGIVQLQDLESIYLQDSLPSGPSQDDSLQAFSSPSPSP
                     DSCPSPEEPPSTAGIPQPPSPELQHRRRLPGAQGPEGGTHPPGSLPSMDSGSLWEEDE
                     VFYN"
     exon            232..347
                     /gene="FAM131C"
                     /gene_synonym="C1orf117"
                     /inference="alignment:Splign:2.1.0"
     exon            348..383
                     /gene="FAM131C"
                     /gene_synonym="C1orf117"
                     /inference="alignment:Splign:2.1.0"
     exon            384..477
                     /gene="FAM131C"
                     /gene_synonym="C1orf117"
                     /inference="alignment:Splign:2.1.0"
     exon            478..660
                     /gene="FAM131C"
                     /gene_synonym="C1orf117"
                     /inference="alignment:Splign:2.1.0"
     exon            661..771
                     /gene="FAM131C"
                     /gene_synonym="C1orf117"
                     /inference="alignment:Splign:2.1.0"
     exon            772..1720
                     /gene="FAM131C"
                     /gene_synonym="C1orf117"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1696..1701
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM131C"
                     /gene_synonym="C1orf117"
                     /note="hexamer: ATTAAA"
     polyA_site      1720
                     /gene="FAM131C"
                     /gene_synonym="C1orf117"
                     /note="major polyA site"
ORIGIN      
        1 actgcgcggg aggcggcggc gcgaggcgag ccgggcgcgg cggcagcagg gacgacccag
       61 gctggagctg aggccgagct gagggcgccc gagccccccg ccccgcccgt cctctggctc
      121 cgcagcgctc agccccgggc ccgcggagac atgaacgccc cgcggcccca cgcaccccgg
      181 gcgcagcggc ccggccccgc ggccccgtga tgggctcctg cgtgtcgcga gacctgttca
      241 caagtgccca caagaactgc cccatgcccc agggtgcgga ccccttgaac ccagatctgc
      301 cctcgggccg cactcccacc gtggctccag actgtgtcat tggcaaggac aaacagatgg
      361 atttctgttg ggatccttgg cagaggtgct tccagaccac caacggctac ctgtccgact
      421 ccagatcccg ccccggcaac tacaacgtgg cagccctggc cacctcgtcc cttgtggggg
      481 tggtgcagag catcaaggac cacatcacaa agcccacggc catggcccga ggccgcgtgg
      541 cccacctcat cgagtggaag ggctggagtg cccagccggc aggctgggag ctgtccccag
      601 ctgaggacga gcattactgc tgcctcccgg atgagctgcg tgaggcccgc tttgctgcag
      661 gggtcgccga gcagtttgcc atcacagagg ccacactgag cgcttggtcc tcgctggacg
      721 aagaggagct gcaccccgag aacagccccc aaggcatcgt ccagctccaa gatctggaga
      781 gcatctacct tcaggacagc cttcccagcg gcccctcaca ggatgacagc cttcaggcct
      841 tctcctcgcc cagcccctcc cctgacagct gtccctcacc tgaggagccc cccagcaccg
      901 ctggcatccc gcagcccccc agcccagagc tgcagcatcg gcggcggctg cccggggccc
      961 aaggacccga gggtgggacc caccccccgg gctccctccc ctccatggac agcggctccc
     1021 tctgggagga ggacgaggtg ttctataact gaggtggggg ctgtgctggt ccagcacctg
     1081 ctctcaccat gacctcgcct ggtgggcagc ccaggcatat ctggaccccg gggtccaggg
     1141 cagggcatcc cttgacccct cgggtaggca cagggtaggt gcggcaggga tggggccagt
     1201 gctcatggtg gcctctctgt gcctcggtgg acctgcccca gcagtgggag ccataacccc
     1261 ctcccccttc attacttcac tcaggtgggc accttcccct gcagggtgtc tgccctcagg
     1321 gaactcacgg actctcagag acaccagggc agcctggccc agaggagcaa cagccaggcc
     1381 cccaggagga cagccatgga gagaactgag acccacttac agtggggtct gggaaccctg
     1441 cctgtacctg gggttcagtc cctcccaact ccctccttgt gtctgccccc cagcaaaggt
     1501 ggggtgacca cttctggtag ctaagcacct gctccccggc tctcttcacc caggacatct
     1561 gtctctctgg agtgtctgtc tgtctgtccc tccctctctg aacctgcttc ctccgtgtcc
     1621 cctgctcctc acccctggga gcccactccc cctccttgcg gctccctccc atctcactca
     1681 aggttctctg aggacattaa agtggtggat tcaccctgga
//
