LOCUS       NM_030802               2329 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens family with sequence similarity 117 member A
            (FAM117A), transcript variant 1, mRNA.
ACCESSION   NM_030802
VERSION     NM_030802.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2329)
  AUTHORS   Wu,C., Zhang,J., Wang,K., Fan,M. and Hu,Y.
  TITLE     FAM117A Is a New Prognostic Marker of Lung Adenocarcinoma and
            Predicts Sensitivity to PD0332991
  JOURNAL   Evid Based Complement Alternat Med 2022, 3945446 (2022)
   PUBMED   35280504
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC037572.1.
            
            On Nov 22, 2018 this sequence version replaced NM_030802.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC065199.1, BC037572.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000240364.7/ ENSP00000240364.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2329              BC037572.1         38-2366
FEATURES             Location/Qualifiers
     source          1..2329
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.33"
     gene            1..2329
                     /gene="FAM117A"
                     /note="family with sequence similarity 117 member A"
                     /db_xref="GeneID:81558"
                     /db_xref="HGNC:HGNC:24179"
     exon            1..240
                     /gene="FAM117A"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..1406
                     /gene="FAM117A"
                     /note="isoform 1 is encoded by transcript variant 1;
                     C/EBP-induced protein; protein FAM117A"
                     /codon_start=1
                     /product="protein FAM117A isoform 1"
                     /protein_id="NP_110429.1"
                     /db_xref="CCDS:CCDS11553.1"
                     /db_xref="GeneID:81558"
                     /db_xref="HGNC:HGNC:24179"
                     /translation="MAGAAAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPL
                     RATIPFQLQQPHQRRDGGGRAASVPCSVAPEKSVCRPQPLQVRRTFSLDTILSSYLLG
                     QWPRDADGAFTCCTNDKATQTPLSWQELEGERASSCAHKRSASWGSTDHRKEISKLKQ
                     QLQRTKLSRSGKEKERGSPLLGDHAVRGALRASPPSFPSGSPVLRLSPCLHRSLEGLN
                     QELEEVFVKEQGEEELLRILDIPDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLA
                     SPQPCGLASHEEHRGAAEELASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSY
                     IFKREPPEGCEKVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFP
                     GMGFIFRNCPSNPGSPLPPASPRPPPRKDPEASKASPLPFEPWQRTPPSEEPVLFQSS
                     LMV"
     exon            241..410
                     /gene="FAM117A"
                     /inference="alignment:Splign:2.1.0"
     exon            411..506
                     /gene="FAM117A"
                     /inference="alignment:Splign:2.1.0"
     exon            507..617
                     /gene="FAM117A"
                     /inference="alignment:Splign:2.1.0"
     exon            618..752
                     /gene="FAM117A"
                     /inference="alignment:Splign:2.1.0"
     exon            753..954
                     /gene="FAM117A"
                     /inference="alignment:Splign:2.1.0"
     exon            955..1105
                     /gene="FAM117A"
                     /inference="alignment:Splign:2.1.0"
     exon            1106..2329
                     /gene="FAM117A"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2313..2318
                     /regulatory_class="polyA_signal_sequence"
                     /gene="FAM117A"
                     /note="hexamer: AATAAA"
     polyA_site      2329
                     /gene="FAM117A"
                     /note="major polyA site"
ORIGIN      
        1 gtgtgagtct cgcagtgggg ctgaggcagg cagccgggag agccatggcg ggggccgcag
       61 cgggcggcag aggcggaggt gcctgggggc cggggcgcgg aggggccggg gggctccggc
      121 ggggctgctc tcccccagcc cccgccggct ccccccgggc tgggctgcag ccgctcaggg
      181 ccacgatccc cttccagctg cagcagccgc accagcgccg ggacgggggt ggccgtgcag
      241 ccagcgtccc atgctcggtg gccccagaaa agtcagtgtg taggcctcag ccacttcagg
      301 tccggcgtac attctccctg gacaccatcc tcagctccta ccttctgggc cagtggccac
      361 gagatgctga tggggccttc acctgctgca ccaatgacaa ggccacccag acgcccctgt
      421 cctggcaaga gctagaaggt gagcgtgcca gttcctgtgc acacaagcgc tcagcatcct
      481 ggggcagcac agaccaccga aaagagattt ccaagttgaa gcaacaactg cagaggacga
      541 agctgagccg cagtgggaaa gagaaggagc gaggttcacc actcctaggg gaccacgcag
      601 tgcggggagc actgagggcg tcccctccca gcttcccctc agggtcccct gtcttgcgac
      661 tcagcccctg cctgcacagg agcctggaag ggctcaacca agagctggag gaggtatttg
      721 tgaaggagca gggagaagag gagctgctga ggatccttga tatccctgat gggcaccggg
      781 ccccagctcc tccccagagt ggcagctgtg atcatcccct cctcctcctg gagcctggca
      841 accttgccag ctctccttcc atgtccttgg catctcccca gccttgtggc ctggccagtc
      901 atgaggaaca tcggggtgcc gccgaggagc tggcatccac ccccaacgac aaagcctcct
      961 ctccaggaca cccagccttt cttgaagatg gcagcccatc tccagtcctt gcctttgctg
     1021 cctcccctcg acctaatcat agctacatct tcaaacggga gcccccagaa ggctgtgaga
     1081 aagtgcgtgt gtttgaagaa gccacgtctc caggtcctga cctggccttc ctgacttcct
     1141 gtcctgacaa gaacaaagtc catttcaacc cgactggctc agccttctgc cccgtcaacc
     1201 tgatgaagcc cctcttcccc ggcatgggct tcatcttccg taactgcccc tcaaacccgg
     1261 gatctcccct tcccccggcc agccccaggc caccacctcg gaaggatccg gaagcctcca
     1321 aggcctcccc actgccattc gagccatggc agcgcacccc accatcagaa gagcctgtgc
     1381 ttttccagag ctccctgatg gtctgagggt cccacccctg ccccacttta ccatagagac
     1441 cagtgccttg gtggcaggtc cctccccagg tcccctgaga tggggtatgg aggggccctt
     1501 ccctctcggc cttcgagcac tttctttcac ttactgtgtc aaagccctgg gtcctctttt
     1561 tgatgggcac cggcccctct gaacgtgatg ggacctgcct tctccactag tagctgggca
     1621 gctcacaatt cacacctgtg tacctgccac atccctcact tggtggaaaa cacccagaag
     1681 gtcttgagtc ccccacccct gggtgtcagt ccaaatgact gtataggagg cccttatttt
     1741 tgtcacagag caagctggcc atgaacgaag gagagaagac gccacagatt tccttccctc
     1801 tcctccagga gaccataaga tagatccccc atcctctcag ccctattccc atgcctccct
     1861 ctcattggag gagctgacca aagcagccct aacgggccat aacacttgac caattcagct
     1921 gctggcagag ggaggaaaca agtgttttcc caagtggcat tttcatctcg ctttcaccct
     1981 gactaaagat tgtcttaagt agcagcccag cccgcccagc cccaggtggg tagtggggag
     2041 gagagctggc attcctccag gtggcaaatg gcgactctat actctccgcc cgccccaggg
     2101 ctggatggat tagaaaaatg cctatttttc ttgtatcgat gtagagactc tattttctcc
     2161 caaagacact atttttgcag ctgtttgaag tttgtatatt ttccgtactg cagagcttac
     2221 acaaaattga agaatgttaa tgttcgagtt ttcttatctt gtgtttagag gttgtttttt
     2281 gcagatcttg gtgttaatag accaaataaa taaataaata ttcccagca
//
