LOCUS       XM_047449817            2639 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens coagulation factor XI (F11), transcript
            variant X11, mRNA.
ACCESSION   XM_047449817
VERSION     XM_047449817.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2639
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..2639
                     /gene="F11"
                     /gene_synonym="FXI; PTA"
                     /note="coagulation factor XI; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 8 ESTs, 51 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     13 samples with support for all annotated introns"
                     /db_xref="GeneID:2160"
                     /db_xref="HGNC:HGNC:3529"
                     /db_xref="MIM:264900"
     CDS             109..1572
                     /gene="F11"
                     /gene_synonym="FXI; PTA"
                     /codon_start=1
                     /product="coagulation factor XI isoform X11"
                     /protein_id="XP_047305773.1"
                     /db_xref="GeneID:2160"
                     /db_xref="HGNC:HGNC:3529"
                     /db_xref="MIM:264900"
                     /translation="MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAK
                     YCQVVCTYHPRCLLFTFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQ
                     CSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLE
                     HRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPELDIVAAKSHEACQKLCTNA
                     VRCQFFTYTPAQASCNEGKGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNECTT
                     KIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPK
                     ILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDKIQN
                     TLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWH
                     LVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV"
ORIGIN      
        1 gaccatttcc tacacaagct cattcagagg aggatgaaga ccattttgga ggaagaaaag
       61 cacccttatt aagaattgca gcaagtaagc caacaaggtc ttttcaggat gattttctta
      121 tatcaagtgg tacatttcat tttatttact tcagtttctg gtgaatgtgt gactcagttg
      181 ttgaaggaca cctgctttga aggaggggac attactacgg tcttcacacc aagcgccaag
      241 tactgccagg tagtctgcac ttaccaccca agatgtttac tcttcacttt cacggcggaa
      301 tcaccatctg aggatcccac ccgatggttt acttgtgtcc tgaaagacag tgttacagaa
      361 acactgccaa gagtgaatag gacagcagcg atttctgggt attctttcaa gcaatgctca
      421 caccaaataa gcgcttgcaa caaagacatt tatgtggacc tagacatgaa gggcataaac
      481 tataacagct cagttgccaa gagtgctcaa gaatgccaag aaagatgcac ggatgacgtc
      541 cactgccact ttttcacgta cgccacaagg cagtttccca gcctggagca tcgaaatctt
      601 tgtctcctta aaacatctga gagtggattg cccagtacac gcattaaaaa gagcaaagct
      661 ctttctggtt tcagtctaca aagctgcagg cacagcatcc cagaactgga tattgttgct
      721 gcaaaaagtc acgaggcctg ccagaaactg tgcaccaatg ccgtccgctg ccagtttttt
      781 acctataccc cagcccaagc atcctgcaac gaagggaagg gcaagtgtta cttaaagctt
      841 tcttcaaacg gatctccaac taaaatactt cacgggagag gaggcatctc tggatacaca
      901 ttaaggttgt gtaaaatgga taatgagtgt accaccaaaa tcaagcccag gatcgttgga
      961 ggaactgcgt ctgttcgtgg tgagtggccg tggcaggtga ccctgcacac aacctcaccc
     1021 actcagagac acctgtgtgg aggctccatc attggaaacc agtggatatt aacagccgct
     1081 cactgtttct atggggtaga gtcacctaag attttgcgtg tctacagtgg cattttaaat
     1141 caatctgaaa taaaagagga cacatctttc tttggggttc aagaaataat aatccatgat
     1201 cagtataaaa tggcagaaag cgggtatgat attgccttgt tgaaactgga aaccacagtg
     1261 aattacacag acaaaataca aaatactctc cagaaagcca agataccctt agtgaccaac
     1321 gaagagtgcc agaagagata cagaggacat aaaataaccc ataagatgat ctgtgccggc
     1381 tacagggaag gagggaagga cgcttgcaag ggagattcgg gaggccctct gtcctgcaaa
     1441 cacaatgagg tctggcatct ggtaggcatc acgagctggg gcgaaggctg tgctcaaagg
     1501 gagcggccag gtgtttacac caacgtggtc gagtacgtgg actggattct ggagaaaact
     1561 caagcagtgt gaatgggttc ccaggggcca ttggagtccc tgaaggaccc aggatttgct
     1621 gggagagggt gttgagttca ctgtgccagc atgcttcctc cacagtaaca cgctgaaggg
     1681 gcttggtgtt tgtaagaaaa tgctagaaga aaacaaactg tcacaagttg ttatgtccaa
     1741 aactcccgtt ctatgatcgt tgtagtttgt ttgagcattc agtctctttg tttttgatca
     1801 cgcttctatg gagtccaaga attaccataa ggcaatattt ctgaagatta ctatataggc
     1861 agatatagca gaaaataacc aagtagtggc agtggggatc aggcagaaga actggtaaaa
     1921 gaagccacca taaatagatt tgttcgatga aagatgaaaa ctggaagaaa ggagaacaaa
     1981 gacagtcttc accattttgc aggaatctac actctgccta tgtgaacaca tttcttttgt
     2041 aaagaaagaa attgattgca tttaatggca gattttcaga atagtcagga attcttgtca
     2101 tttccatttt aaaatatata ttaaaaaaaa tcagttcgag tagacacgag ctaagagtga
     2161 atgtgaagat aacagaattt ctgtgtggaa gaggattaca agcagcaatt tacctggaag
     2221 tgatacctta ggggcaatct tgaagataca ctttcctgaa aaatgatttg tgatggattg
     2281 tatatttatt taaaatatct tgggagggga ggctgatgga gatagggagc atgctcaaac
     2341 ctccctaaga caagctgctg ctgtgactat gggctcccaa agagctagat cgtatattta
     2401 tttgacaaaa atcaccatag actgcatcca tactacagag aaaaaacaat tagggcgcaa
     2461 atggatagtt acagtaaagt cttcagcaag cagctgcctg tattctaagc actgggattt
     2521 tctgtttcgt gcaaatattt atctcattat tgttgtgatc tagttcaata acctagaatt
     2581 tgaattgtca ccacatagct ttcaatctgt gccaacaact atacaattca tcaagtgtg
//
