LOCUS       XM_017007886            1359 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens coagulation factor XI (F11), transcript
            variant X14, mRNA.
ACCESSION   XM_017007886
VERSION     XM_017007886.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017007886.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1359
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..1359
                     /gene="F11"
                     /gene_synonym="FXI; PTA"
                     /note="coagulation factor XI; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 13 ESTs, 26 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     21 samples with support for all annotated introns"
                     /db_xref="GeneID:2160"
                     /db_xref="HGNC:HGNC:3529"
                     /db_xref="MIM:264900"
     CDS             109..1293
                     /gene="F11"
                     /gene_synonym="FXI; PTA"
                     /codon_start=1
                     /product="coagulation factor XI isoform X13"
                     /protein_id="XP_016863375.1"
                     /db_xref="GeneID:2160"
                     /db_xref="HGNC:HGNC:3529"
                     /db_xref="MIM:264900"
                     /translation="MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAK
                     YCQVVCTYHPRCLLFTFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQ
                     CSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLE
                     HRNICLLKHTQTGTPTRITKLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSV
                     MAPDAFVCGRICTHHPGCLFFTFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALS
                     GFSLQSCRHSIPVFCHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTP
                     AQASCNEGKGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNELRGAPMKISGWLK
                     TS"
     polyA_site      1359
                     /gene="F11"
                     /gene_synonym="FXI; PTA"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gaccatttcc tacacaagct cattcagagg aggatgaaga ccattttgga ggaagaaaag
       61 cacccttatt aagaattgca gcaagtaagc caacaaggtc ttttcaggat gattttctta
      121 tatcaagtgg tacatttcat tttatttact tcagtttctg gtgaatgtgt gactcagttg
      181 ttgaaggaca cctgctttga aggaggggac attactacgg tcttcacacc aagcgccaag
      241 tactgccagg tagtctgcac ttaccaccca agatgtttac tcttcacttt cacggcggaa
      301 tcaccatctg aggatcccac ccgatggttt acttgtgtcc tgaaagacag tgttacagaa
      361 acactgccaa gagtgaatag gacagcagcg atttctgggt attctttcaa gcaatgctca
      421 caccaaataa gcgcttgcaa caaagacatt tatgtggacc tagacatgaa gggcataaac
      481 tataacagct cagttgccaa gagtgctcaa gaatgccaag aaagatgcac ggatgacgtc
      541 cactgccact ttttcacgta cgccacaagg cagtttccca gcctggagca tcgtaacatt
      601 tgtctactga agcacaccca aacagggaca ccaaccagaa taacgaagct cgataaagtg
      661 gtgtctggat tttcactgaa atcctgtgca ctttctaatc tggcttgtat tagggacatt
      721 ttccctaata cggtgtttgc agacagcaac atcgacagtg tcatggctcc cgatgctttt
      781 gtctgtggcc gaatctgcac tcatcatccc ggttgcttgt tttttacctt cttttcccag
      841 gaatggccca aagaatctca aagaaatctt tgtctcctta aaacatctga gagtggattg
      901 cccagtacac gcattaaaaa gagcaaagct ctttctggtt tcagtctaca aagctgcagg
      961 cacagcatcc cagtgttctg ccattcttca ttttaccatg acactgattt cttgggagaa
     1021 gaactggata ttgttgctgc aaaaagtcac gaggcctgcc agaaactgtg caccaatgcc
     1081 gtccgctgcc agttttttac ctatacccca gcccaagcat cctgcaacga agggaagggc
     1141 aagtgttact taaagctttc ttcaaacgga tctccaacta aaatacttca cgggagagga
     1201 ggcatctctg gatacacatt aaggttgtgt aaaatggata atgagcttag aggcgctccg
     1261 atgaaaatct ctggatggct caagacttct taaaaagcaa gtcaattacg tcgtatctca
     1321 tacattctgt tttcctcaca ataaatttcc ctaagacaa
//
