LOCUS       XM_006714137            3008 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens coagulation factor XI (F11), transcript
            variant X2, mRNA.
ACCESSION   XM_006714137
VERSION     XM_006714137.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006714137.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3008
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..3008
                     /gene="F11"
                     /gene_synonym="FXI; PTA"
                     /note="coagulation factor XI; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 15 ESTs, 58 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     16 samples with support for all annotated introns"
                     /db_xref="GeneID:2160"
                     /db_xref="HGNC:HGNC:3529"
                     /db_xref="MIM:264900"
     CDS             109..1941
                     /gene="F11"
                     /gene_synonym="FXI; PTA"
                     /codon_start=1
                     /product="coagulation factor XI isoform X2"
                     /protein_id="XP_006714200.1"
                     /db_xref="GeneID:2160"
                     /db_xref="HGNC:HGNC:3529"
                     /db_xref="MIM:264900"
                     /translation="MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAK
                     YCQVVCTYHPRCLLFTFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQ
                     CSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLE
                     HRNICLLKHTQTGTPTRITKLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSV
                     MAPDAFVCGRICTHHPGCLFFTFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALS
                     GFSLQSCRHSIPELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGNRGKCYLK
                     LSSNGSPTKILHGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHT
                     TSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQE
                     IIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRK
                     LRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSC
                     KHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV"
ORIGIN      
        1 gaccatttcc tacacaagct cattcagagg aggatgaaga ccattttgga ggaagaaaag
       61 cacccttatt aagaattgca gcaagtaagc caacaaggtc ttttcaggat gattttctta
      121 tatcaagtgg tacatttcat tttatttact tcagtttctg gtgaatgtgt gactcagttg
      181 ttgaaggaca cctgctttga aggaggggac attactacgg tcttcacacc aagcgccaag
      241 tactgccagg tagtctgcac ttaccaccca agatgtttac tcttcacttt cacggcggaa
      301 tcaccatctg aggatcccac ccgatggttt acttgtgtcc tgaaagacag tgttacagaa
      361 acactgccaa gagtgaatag gacagcagcg atttctgggt attctttcaa gcaatgctca
      421 caccaaataa gcgcttgcaa caaagacatt tatgtggacc tagacatgaa gggcataaac
      481 tataacagct cagttgccaa gagtgctcaa gaatgccaag aaagatgcac ggatgacgtc
      541 cactgccact ttttcacgta cgccacaagg cagtttccca gcctggagca tcgtaacatt
      601 tgtctactga agcacaccca aacagggaca ccaaccagaa taacgaagct cgataaagtg
      661 gtgtctggat tttcactgaa atcctgtgca ctttctaatc tggcttgtat tagggacatt
      721 ttccctaata cggtgtttgc agacagcaac atcgacagtg tcatggctcc cgatgctttt
      781 gtctgtggcc gaatctgcac tcatcatccc ggttgcttgt tttttacctt cttttcccag
      841 gaatggccca aagaatctca aagaaatctt tgtctcctta aaacatctga gagtggattg
      901 cccagtacac gcattaaaaa gagcaaagct ctttctggtt tcagtctaca aagctgcagg
      961 cacagcatcc cagaactgga tattgttgct gcaaaaagtc acgaggcctg ccagaaactg
     1021 tgcaccaatg ccgtccgctg ccagtttttt acctataccc cagcccaagc atcctgcaac
     1081 gaagggaaca ggggcaagtg ttacttaaag ctttcttcaa acggatctcc aactaaaata
     1141 cttcacggga gaggaggcat ctctggatac acattaaggt tgtgtaaaat ggataatgag
     1201 tgtaccacca aaatcaagcc caggatcgtt ggaggaactg cgtctgttcg tggtgagtgg
     1261 ccgtggcagg tgaccctgca cacaacctca cccactcaga gacacctgtg tggaggctcc
     1321 atcattggaa accagtggat attaacagcc gctcactgtt tctatggggt agagtcacct
     1381 aagattttgc gtgtctacag tggcatttta aatcaatctg aaataaaaga ggacacatct
     1441 ttctttgggg ttcaagaaat aataatccat gatcagtata aaatggcaga aagcgggtat
     1501 gatattgcct tgttgaaact ggaaaccaca gtgaattaca cagattctca acgacccata
     1561 tgcctgcctt ccaaaggaga tagaaatgta atatacactg attgctgggt gactggatgg
     1621 gggtacagaa aactaagaga caaaatacaa aatactctcc agaaagccaa gataccctta
     1681 gtgaccaacg aagagtgcca gaagagatac agaggacata aaataaccca taagatgatc
     1741 tgtgccggct acagggaagg agggaaggac gcttgcaagg gagattcggg aggccctctg
     1801 tcctgcaaac acaatgaggt ctggcatctg gtaggcatca cgagctgggg cgaaggctgt
     1861 gctcaaaggg agcggccagg tgtttacacc aacgtggtcg agtacgtgga ctggattctg
     1921 gagaaaactc aagcagtgtg aatgggttcc caggggccat tggagtccct gaaggaccca
     1981 ggatttgctg ggagagggtg ttgagttcac tgtgccagca tgcttcctcc acagtaacac
     2041 gctgaagggg cttggtgttt gtaagaaaat gctagaagaa aacaaactgt cacaagttgt
     2101 tatgtccaaa actcccgttc tatgatcgtt gtagtttgtt tgagcattca gtctctttgt
     2161 ttttgatcac gcttctatgg agtccaagaa ttaccataag gcaatatttc tgaagattac
     2221 tatataggca gatatagcag aaaataacca agtagtggca gtggggatca ggcagaagaa
     2281 ctggtaaaag aagccaccat aaatagattt gttcgatgaa agatgaaaac tggaagaaag
     2341 gagaacaaag acagtcttca ccattttgca ggaatctaca ctctgcctat gtgaacacat
     2401 ttcttttgta aagaaagaaa ttgattgcat ttaatggcag attttcagaa tagtcaggaa
     2461 ttcttgtcat ttccatttta aaatatatat taaaaaaaat cagttcgagt agacacgagc
     2521 taagagtgaa tgtgaagata acagaatttc tgtgtggaag aggattacaa gcagcaattt
     2581 acctggaagt gataccttag gggcaatctt gaagatacac tttcctgaaa aatgatttgt
     2641 gatggattgt atatttattt aaaatatctt gggaggggag gctgatggag atagggagca
     2701 tgctcaaacc tccctaagac aagctgctgc tgtgactatg ggctcccaaa gagctagatc
     2761 gtatatttat ttgacaaaaa tcaccataga ctgcatccat actacagaga aaaaacaatt
     2821 agggcgcaaa tggatagtta cagtaaagtc ttcagcaagc agctgcctgt attctaagca
     2881 ctgggatttt ctgtttcgtg caaatattta tctcattatt gttgtgatct agttcaataa
     2941 cctagaattt gaattgtcac cacatagctt tcaatctgtg ccaacaacta tacaattcat
     3001 caagtgtg
//
