LOCUS       NM_001382422            3191 bp    mRNA    linear   PRI 18-SEP-2024
DEFINITION  Homo sapiens exocyst complex component 3 like 2 (EXOC3L2), mRNA.
ACCESSION   NM_001382422
VERSION     NM_001382422.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3191)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 3191)
  AUTHORS   Shalata,A., Lauhasurayotin,S., Leibovitz,Z., Li,H., Hebert,D.,
            Dhanraj,S., Hadid,Y., Mahroum,M., Bajar,J., Egenburg,S., Arad,A.,
            Shohat,M., Haddad,S., Bakry,H., Moshiri,H., Scherer,S.W., Tzur,S.
            and Dror,Y.
  TITLE     Biallelic mutations in EXOC3L2 cause a novel syndrome that affects
            the brain, kidney and blood
  JOURNAL   J Med Genet 56 (5), 340-346 (2019)
   PUBMED   30327448
  REMARK    GeneRIF: We propose that biallelic EXOC3L2 mutations lead to a
            novel syndrome that affects hindbrain development, kidney and
            possibly the bone marrow.
REFERENCE   3  (bases 1 to 3191)
  AUTHORS   Wu,Q.J., Sun,S.Y., Yan,C.J., Cheng,Z.C., Yang,M.F., Li,Z.F.,
            Cheng,H.W. and Fang,T.K.
  TITLE     EXOC3L2 rs597668 variant contributes to Alzheimer's disease
            susceptibility in Asian population
  JOURNAL   Oncotarget 8 (12), 20086-20091 (2017)
   PUBMED   28423615
  REMARK    GeneRIF: EXOC3L2 rs597668 variant is associated with Alzheimer's
            disease susceptibility.
REFERENCE   4  (bases 1 to 3191)
  AUTHORS   Perez-Palma,E., Bustos,B.I., Villaman,C.F., Alarcon,M.A.,
            Avila,M.E., Ugarte,G.D., Reyes,A.E., Opazo,C. and De Ferrari,G.V.
  CONSRTM   Alzheimer's Disease Neuroimaging Initiative; NIA-LOAD/NCRAD Family
            Study Group
  TITLE     Overrepresentation of glutamate signaling in Alzheimer's disease:
            network-based pathway enrichment using meta-analysis of genome-wide
            association studies
  JOURNAL   PLoS One 9 (4), e95413 (2014)
   PUBMED   24755620
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3191)
  AUTHORS   Shang,H., Fu,J., Zhang,X.M., Song,R.R. and Wang,W.Z.
  TITLE     Association between EXOC3L2 rs597668 polymorphism and Alzheimer's
            disease
  JOURNAL   CNS Neurosci Ther 19 (10), 834-839 (2013)
   PUBMED   23663385
  REMARK    GeneRIF: This meta-analysis assesses an association between
            rs597668 polymorphism in EXOC3L2 and Alzheimer's disease.
REFERENCE   6  (bases 1 to 3191)
  AUTHORS   Liu,Q.Y., Miao,D., Yu,J.T., Xing,Y.Y., Zhong,X.L., Wu,Z.C.,
            Zhang,Q. and Tan,L.
  TITLE     Lack of association between rs597668 polymorphism near EXOC3L2 and
            late-onset Alzheimer's disease in Han Chinese
  JOURNAL   Neurosci Lett 513 (2), 174-177 (2012)
   PUBMED   22381399
  REMARK    GeneRIF: This study suggests that the rs597668 polymorphism near
            EXOC3L2 may not play a major role in the susceptibility to
            late-onset Alzheimer's disease in the Northern Han Chinese
            population.
REFERENCE   7  (bases 1 to 3191)
  AUTHORS   Gieger,C., Radhakrishnan,A., Cvejic,A., Tang,W., Porcu,E.,
            Pistis,G., Serbanovic-Canic,J., Elling,U., Goodall,A.H.,
            Labrune,Y., Lopez,L.M., Magi,R., Meacham,S., Okada,Y., Pirastu,N.,
            Sorice,R., Teumer,A., Voss,K., Zhang,W., Ramirez-Solis,R.,
            Bis,J.C., Ellinghaus,D., Gogele,M., Hottenga,J.J., Langenberg,C.,
            Kovacs,P., O'Reilly,P.F., Shin,S.Y., Esko,T., Hartiala,J.,
            Kanoni,S., Murgia,F., Parsa,A., Stephens,J., van der Harst,P.,
            Ellen van der Schoot,C., Allayee,H., Attwood,A., Balkau,B.,
            Bastardot,F., Basu,S., Baumeister,S.E., Biino,G., Bomba,L.,
            Bonnefond,A., Cambien,F., Chambers,J.C., Cucca,F., D'Adamo,P.,
            Davies,G., de Boer,R.A., de Geus,E.J., Doring,A., Elliott,P.,
            Erdmann,J., Evans,D.M., Falchi,M., Feng,W., Folsom,A.R.,
            Frazer,I.H., Gibson,Q.D., Glazer,N.L., Hammond,C.,
            Hartikainen,A.L., Heckbert,S.R., Hengstenberg,C., Hersch,M.,
            Illig,T., Loos,R.J., Jolley,J., Khaw,K.T., Kuhnel,B.,
            Kyrtsonis,M.C., Lagou,V., Lloyd-Jones,H., Lumley,T., Mangino,M.,
            Maschio,A., Mateo Leach,I., McKnight,B., Memari,Y., Mitchell,B.D.,
            Montgomery,G.W., Nakamura,Y., Nauck,M., Navis,G., Nothlings,U.,
            Nolte,I.M., Porteous,D.J., Pouta,A., Pramstaller,P.P., Pullat,J.,
            Ring,S.M., Rotter,J.I., Ruggiero,D., Ruokonen,A., Sala,C.,
            Samani,N.J., Sambrook,J., Schlessinger,D., Schreiber,S.,
            Schunkert,H., Scott,J., Smith,N.L., Snieder,H., Starr,J.M.,
            Stumvoll,M., Takahashi,A., Tang,W.H., Taylor,K., Tenesa,A., Lay
            Thein,S., Tonjes,A., Uda,M., Ulivi,S., van Veldhuisen,D.J.,
            Visscher,P.M., Volker,U., Wichmann,H.E., Wiggins,K.L.,
            Willemsen,G., Yang,T.P., Hua Zhao,J., Zitting,P., Bradley,J.R.,
            Dedoussis,G.V., Gasparini,P., Hazen,S.L., Metspalu,A., Pirastu,M.,
            Shuldiner,A.R., Joost van Pelt,L., Zwaginga,J.J., Boomsma,D.I.,
            Deary,I.J., Franke,A., Froguel,P., Ganesh,S.K., Jarvelin,M.R.,
            Martin,N.G., Meisinger,C., Psaty,B.M., Spector,T.D., Wareham,N.J.,
            Akkerman,J.W., Ciullo,M., Deloukas,P., Greinacher,A., Jupe,S.,
            Kamatani,N., Khadake,J., Kooner,J.S., Penninger,J., Prokopenko,I.,
            Stemple,D., Toniolo,D., Wernisch,L., Sanna,S., Hicks,A.A.,
            Rendon,A., Ferreira,M.A., Ouwehand,W.H. and Soranzo,N.
  TITLE     New gene functions in megakaryopoiesis and platelet formation
  JOURNAL   Nature 480 (7376), 201-208 (2011)
   PUBMED   22139419
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 3191)
  AUTHORS   Barkefors,I., Fuchs,P.F., Heldin,J., Bergstrom,T.,
            Forsberg-Nilsson,K. and Kreuger,J.
  TITLE     Exocyst complex component 3-like 2 (EXOC3L2) associates with the
            exocyst complex and mediates directional migration of endothelial
            cells
  JOURNAL   J Biol Chem 286 (27), 24189-24199 (2011)
   PUBMED   21566143
  REMARK    GeneRIF: exoc3l2 silencing inhibits VEGF receptor 2 phosphorylation
            and VEGFA-directed migration of cultured endothelial cells.
REFERENCE   9  (bases 1 to 3191)
  AUTHORS   Seshadri,S., Fitzpatrick,A.L., Ikram,M.A., DeStefano,A.L.,
            Gudnason,V., Boada,M., Bis,J.C., Smith,A.V., Carassquillo,M.M.,
            Lambert,J.C., Harold,D., Schrijvers,E.M., Ramirez-Lorca,R.,
            Debette,S., Longstreth,W.T. Jr., Janssens,A.C., Pankratz,V.S.,
            Dartigues,J.F., Hollingworth,P., Aspelund,T., Hernandez,I.,
            Beiser,A., Kuller,L.H., Koudstaal,P.J., Dickson,D.W., Tzourio,C.,
            Abraham,R., Antunez,C., Du,Y., Rotter,J.I., Aulchenko,Y.S.,
            Harris,T.B., Petersen,R.C., Berr,C., Owen,M.J., Lopez-Arrieta,J.,
            Varadarajan,B.N., Becker,J.T., Rivadeneira,F., Nalls,M.A.,
            Graff-Radford,N.R., Campion,D., Auerbach,S., Rice,K., Hofman,A.,
            Jonsson,P.V., Schmidt,H., Lathrop,M., Mosley,T.H., Au,R.,
            Psaty,B.M., Uitterlinden,A.G., Farrer,L.A., Lumley,T., Ruiz,A.,
            Williams,J., Amouyel,P., Younkin,S.G., Wolf,P.A., Launer,L.J.,
            Lopez,O.L., van Duijn,C.M. and Breteler,M.M.
  CONSRTM   CHARGE Consortium; GERAD1 Consortium; EADI1 Consortium
  TITLE     Genome-wide analysis of genetic loci associated with Alzheimer
            disease
  JOURNAL   JAMA 303 (18), 1832-1840 (2010)
   PUBMED   20460622
  REMARK    GeneRIF: Observational study, meta-analysis, and genome-wide
            association study of gene-disease association and gene-gene
            interaction. (HuGE Navigator)
REFERENCE   10 (bases 1 to 3191)
  AUTHORS   Lowe,J.K., Maller,J.B., Pe'er,I., Neale,B.M., Salit,J., Kenny,E.E.,
            Shea,J.L., Burkhardt,R., Smith,J.G., Ji,W., Noel,M., Foo,J.N.,
            Blundell,M.L., Skilling,V., Garcia,L., Sullivan,M.L., Lee,H.E.,
            Labek,A., Ferdowsian,H., Auerbach,S.B., Lifton,R.P.,
            Newton-Cheh,C., Breslow,J.L., Stoffel,M., Daly,M.J., Altshuler,D.M.
            and Friedman,J.M.
  TITLE     Genome-wide association studies in an isolated founder population
            from the Pacific Island of Kosrae
  JOURNAL   PLoS Genet 5 (2), e1000365 (2009)
   PUBMED   19197348
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC006126.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: The protein encoded by this gene is upregulated by
            vascular endothelial growth factor A and interacts with exocyst
            complex component 4. The encoded protein may be part of an exocyst
            complex that plays a role in cell membrane dynamics. Mutations in
            this gene may be associated with Alzheimer's disease. [provided by
            RefSeq, May 2017].
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13170464.1348179.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000413988.3/ ENSP00000400713.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                AC006126.1         36814-36880         c
            68-606              AC006126.1         29996-30534         c
            607-1240            AC006126.1         25666-26299         c
            1241-1352           AC006126.1         23236-23347         c
            1353-1454           AC006126.1         19638-19739         c
            1455-1555           AC006126.1         19447-19547         c
            1556-1666           AC006126.1         19135-19245         c
            1667-1802           AC006126.1         16251-16386         c
            1803-1925           AC006126.1         9670-9792           c
            1926-2081           AC006126.1         9001-9156           c
            2082-2203           AC006126.1         7546-7667           c
            2204-3191           AC006126.1         3843-4830           c
FEATURES             Location/Qualifiers
     source          1..3191
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.32"
     gene            1..3191
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /note="exocyst complex component 3 like 2"
                     /db_xref="GeneID:90332"
                     /db_xref="HGNC:HGNC:30162"
                     /db_xref="MIM:616927"
     exon            1..67
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /inference="alignment:Splign:2.1.0"
     exon            68..606
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..2492
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /note="HBV X-transactivated gene 7 protein; protein 7
                     transactivated by hepatitis B virus X antigen (HBxAg); HBV
                     XAg-transactivated protein 7"
                     /codon_start=1
                     /product="exocyst complex component 3-like protein 2"
                     /protein_id="NP_001369351.1"
                     /db_xref="CCDS:CCDS92642.1"
                     /db_xref="GeneID:90332"
                     /db_xref="HGNC:HGNC:30162"
                     /db_xref="MIM:616927"
                     /translation="MPILKNLGVSDPKVPRAGTLPLRSSRNPFEEVSGLEEEEAGELG
                     SLPNGTSCRRRATLEKLAGLAPFRLGWAPGRRAGSPGDGQPRSFLGRVLVPGIRRSSA
                     DFGLLARLHGTRAHGDEEAAGEAARRLAFLRLGRGSKPQRASLAERVVPAGEAAPEPP
                     PKVPEPPKMKEPLSVLEILSLIQQRELARADEHILELEAEELAPSRGGAPGPPKAEGA
                     GGGRRARDVALLYEALQRELWALVRETLAGPGPGACAGAGAVAQLGQVLVQEEAADGR
                     RGPGAARKLRARWAEAVARAARERLEAAAPGAPGGLAGQLEALRARLLEDMAVVRGRL
                     APAYPAGLGAFGVYLRGYHGALAEWLGASARRRLPLADRYALLHWHNQVYPREVLGLV
                     DMAALENGELGPLLSPGTLRGLEDECVTDVKAQTRAALLRVLQEDEEHWGSLEDQPSS
                     LAQDVCELLEEHTERAPRISQEFGERMAHCCLGGLAEFLQSFQQRVERFHENPAVREM
                     LPDTYISKTIALVNCGPPLRALAERLARVGPPESEPAREASASALDHVTRLCHRVVAN
                     LLFQELQPHFNKLMRRKWLSSPEALDGIVGTLGAQALALRRMQDEPYQALVAELHRRA
                     LVEYVRPLLRGRLRCSSARTRSRVAGRLREDAAQLQRLFRRLESQASWLDAVVPHLAE
                     VMQLEDTPSIQVEVGVLVRDYPDIRQKHVAALLDIRGLRNTAARQEILAVARDLELSE
                     EGALSPPRDRAFFADIPVPRPSFCLSLPLFLGRLPLSRLARPSLACLPRPRPPSLARP
                     RAQR"
     exon            607..1240
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1352
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /inference="alignment:Splign:2.1.0"
     exon            1353..1454
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /inference="alignment:Splign:2.1.0"
     exon            1455..1555
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /inference="alignment:Splign:2.1.0"
     exon            1556..1666
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /inference="alignment:Splign:2.1.0"
     exon            1667..1802
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /inference="alignment:Splign:2.1.0"
     exon            1803..1925
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /inference="alignment:Splign:2.1.0"
     exon            1926..2081
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /inference="alignment:Splign:2.1.0"
     exon            2082..2203
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /inference="alignment:Splign:2.1.0"
     exon            2204..3191
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3166..3171
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /note="hexamer: AATAAA"
     polyA_site      3191
                     /gene="EXOC3L2"
                     /gene_synonym="BMRS; XTP7"
                     /note="major polyA site"
ORIGIN      
        1 agtcctggct gaagtagcct ggggacagga cagcagcggg aacagaagga cgggcaggag
       61 gacagaggtc cccacctgtc aaaatgccta tcctgaagaa tctgggagtg tcagacccta
      121 aggtgccccg ggcggggacc ctgcccctga ggtcctctcg gaaccccttt gaagaagttt
      181 cagggctgga ggaagaagag gccggggagc tggggtccct ccccaatgga acatcttgtc
      241 gccgccgcgc caccctggag aagcttgcgg gcctggcccc cttccggctg ggctgggccc
      301 cgggccggcg ggcaggcagc cctggggatg ggcagccccg ctctttcttg ggccgtgtgc
      361 tggtaccagg gatacgcagg agctcagcag attttggcct cctggcccgg ctgcatggga
      421 cccgagccca cggcgacgag gaggcagcgg gggaggccgc ccggagactg gccttcctga
      481 gactggggcg tggatccaag ccccagcgtg cgtccctggc tgagagagtg gtgcctgcag
      541 gcgaggcagc tccagagccc ccacccaagg tcccagagcc cccaaagatg aaggagccat
      601 tgtcagtgct ggagatcctg agcctgatcc agcagcgcga actagcgcgt gcggacgagc
      661 acatcctgga gctagaggcc gaggagctgg cgccgtcgag gggcggcgcg cctgggcctc
      721 ccaaggccga gggcgctggc gggggccgcc gggcgcggga cgtggcgctg ctgtacgagg
      781 ccctgcagcg cgagctgtgg gcgctggtgc gcgagacgct ggcgggcccc gggccgggag
      841 cgtgcgccgg ggctggcgcg gtggcgcagc tgggccaggt gctggtacag gaggaggcgg
      901 ccgacgggcg tcggggtccc ggggcggccc gcaaactacg cgcacgctgg gccgaagccg
      961 tggcgcgcgc ggcccgggag cgcctagagg cagcggctcc cggggcgccc gggggcctgg
     1021 ccgggcagct ggaggcgctg cgggcgcggc tgctggagga tatggccgtg gtgcggggcc
     1081 gcctggcgcc cgcctacccc gccggcctgg gcgccttcgg cgtctacctg cgcggctacc
     1141 acggggccct ggccgagtgg ctgggggcct ccgcccgtcg caggctgccg ctggccgacc
     1201 gctacgcgct gctgcactgg cacaatcagg tctaccccag agaggtccta gggctggtgg
     1261 acatggccgc cctggagaat ggggagctgg ggccccttct ctcccctggc accctgcggg
     1321 gtttggagga tgaatgcgtc acagatgtta aggctcagac ccgggctgcc cttctccgtg
     1381 tgctgcagga ggacgaagag cactggggga gcctggagga ccagcccagc agcctggccc
     1441 aggatgtgtg tgagctgctg gaagagcaca cagagcgagc accccgcatc agccaggagt
     1501 ttggggagcg gatggcccac tgctgcctag gcgggctggc agagttcctg cagagcttcc
     1561 agcagcgtgt ggagcgattc catgagaacc cagcagtccg ggagatgcta cctgacacct
     1621 atatcagcaa gaccatcgcc ctggtcaact gcggcccccc actgagagct ctggccgagc
     1681 gcctggcccg ggtggggccc ccagaaagcg agccggcccg ggaagcatct gctagtgctc
     1741 tggaccatgt gacccggctc tgccaccgtg tcgtggccaa cctgctgttc caggagctgc
     1801 agccacactt caacaagctg atgcgccgga agtggctgag cagcccggag gccctggatg
     1861 gcatcgtggg cacgctgggt gcccaggccc tggccctgcg cagaatgcag gacgagcctt
     1921 accaggcgct ggtagccgag ctacaccggc gggcgctggt cgagtacgtg cggcccctgc
     1981 tccgtgggcg cctgcgctgc agctcggcgc ggacccgcag ccgcgtggcc ggcaggctcc
     2041 gggaggacgc ggcgcaactg cagaggctgt tccggcggct ggagtcccag gcctcgtggc
     2101 tggatgccgt ggtgccccat ttggctgaag tcatgcagct ggaagacacg cccagcatcc
     2161 aggtggaggt gggagtgttg gtgcgcgact acccagacat caggcagaag cacgtggcag
     2221 ccctcctcga catccgtggc ctgcgcaaca cagccgcccg ccaggagatc ctggccgtgg
     2281 cccgggacct ggaactctct gaggagggag ccctgtcacc ccctcgggac cgtgccttct
     2341 ttgcagacat ccctgtgccc cgcccatctt tctgtctcag cctccctctc ttcctgggcc
     2401 gcctccccct ctcccggctg gccaggccca gtttggcctg tctgcctcgg ccccggcctc
     2461 cgtctctagc gcgacctcgg gcccagcgct gagggtcacc caaccgccgg ccttagtgac
     2521 cccatctatg ctgctgacaa gccaacctcc cgtacggcgc ccctcctgac tccctgcctg
     2581 ggaccacaca cccctgggat agaaagaccc ttagatgtct tttcacccaa ccccaaactc
     2641 cctgtacaga agggaaacaa acgccaggca cggtggctca tgcctgtaat cccaacactt
     2701 tgggaggctg aggccggagg attgcttgag cccaggagtt caagaccagc ctgggcaaca
     2761 tagtgagacc tgccccctat ctctacaaaa aataaaaaat tagctgggca cggtggtgtg
     2821 tgcctgtagt cccagctact ggtgaggctg aggctggagg atcactggag ttcgaggctg
     2881 cagtgagcta tgactgtgcc actgcactcc agcctggtca acaaagcaag accctttctc
     2941 aaaaaaaaaa aaaaaaaaaa aaggtagggg gaaacagagg ccaaagagac aaagcatttt
     3001 cccaaggcca tgaagcctgt tcccagcacc tcccctcctg ccatagccca gagtggtgag
     3061 tgtcgttctg gaagtctcta cagaaatatc ccagctcccc cgcccctttc cctcacctca
     3121 aggtctggcc ccaatccaat gtattaagga acgttcgata cttagaataa agaggtttct
     3181 atttaacaca a
//
