LOCUS       XM_047434104            3517 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens exonuclease 1 (EXO1), transcript variant
            X3, mRNA.
ACCESSION   XM_047434104
VERSION     XM_047434104.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3517
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..3517
                     /gene="EXO1"
                     /gene_synonym="HEX1; hExoI"
                     /note="exonuclease 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 26 ESTs, 377 long
                     SRA reads, 5 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 13 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:9156"
                     /db_xref="HGNC:HGNC:3511"
                     /db_xref="MIM:606063"
     CDS             638..3178
                     /gene="EXO1"
                     /gene_synonym="HEX1; hExoI"
                     /codon_start=1
                     /product="exonuclease 1 isoform X1"
                     /protein_id="XP_047290060.1"
                     /db_xref="GeneID:9156"
                     /db_xref="HGNC:HGNC:3511"
                     /db_xref="MIM:606063"
                     /translation="MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAE
                     KLAKGEPTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLK
                     GKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNK
                     AGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYM
                     CILSGCDYLSSLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFI
                     RANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINT
                     FEQIDDYNPDTAMPAHSRSHSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQLKE
                     NPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYSLSFTKKTKKNSSEGN
                     KSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFC
                     SSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSDDIPNN
                     HIPGDHIPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSP
                     SPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREEACSSQSQESGEF
                     SLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLRLSHFSKKDTPLRNKVPG
                     LYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHNAENKPGLQIKLNELWKNF
                     GFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRVQRAIFQ"
ORIGIN      
        1 agtgccactc gcgccctcaa gaagccgcac ggagttcggg ccggcagcag cggctgcagt
       61 cgtatggcag tgagccgctg tctacccagc gagacggaga gctcaggacg caaccctatg
      121 agttggaagc cgcaggaggc ggaaccgggt tgcgggatac gcgttgacgt cacatcctct
      181 gggcggggcc gcaaggaacc cgcgcaaatt gaaaggccta aggaaacgtg tcgtctggaa
      241 tgggcttggg ggccacgcct gcacatctcc gcgagacaga gggataaagt gaagatggtg
      301 ctgttattgt tacctcgagt gccacatgcg acctctgaga tatgtacaca gtcattctta
      361 ctatcgcact cagccattct tactacgcta aagaagaaat aattattcga ggatatttgc
      421 ctggcccaga agaaacttat gtaaatttca tgaactatta tatccgtttt cctcggagtg
      481 agagaaaact ctttttagat atcatctgag agcagaacta gtgaatccca gtcactgagt
      541 ggagttgaga gtctaagaac ctctgaaatt tgagaactgc tggaccagag cctttagagc
      601 tctgataagg tgtcaacagg gtagttaatt tggcaccatg gggatacagg gattgctaca
      661 atttatcaaa gaagcttcag aacccatcca tgtgaggaag tataaagggc aggtagtagc
      721 tgtggataca tattgctggc ttcacaaagg agctattgct tgtgctgaaa aactagccaa
      781 aggtgaacct actgataggt atgtaggatt ttgtatgaaa tttgtaaata tgttactatc
      841 tcatgggatc aagcctattc tcgtatttga tggatgtact ttaccttcta aaaaggaagt
      901 agagagatct agaagagaaa gacgacaagc caatcttctt aagggaaagc aacttcttcg
      961 tgaggggaaa gtctcggaag ctcgagagtg tttcacccgg tctatcaata tcacacatgc
     1021 catggcccac aaagtaatta aagctgcccg gtctcagggg gtagattgcc tcgtggctcc
     1081 ctatgaagct gatgcgcagt tggcctatct taacaaagcg ggaattgtgc aagccataat
     1141 tacagaggac tcggatctcc tagcttttgg ctgtaaaaag gtaattttaa agatggacca
     1201 gtttggaaat ggacttgaaa ttgatcaagc tcggctagga atgtgcagac agcttgggga
     1261 tgtattcacg gaagagaagt ttcgttacat gtgtattctt tcaggttgtg actacctgtc
     1321 atcactgcgt gggattggat tagcaaaggc atgcaaagtc ctaagactag ccaataatcc
     1381 agatatagta aaggttatca agaaaattgg acattatctc aagatgaata tcacggtacc
     1441 agaggattac atcaacgggt ttattcgggc caacaatacc ttcctctatc agctagtttt
     1501 tgatcccatc aaaaggaaac ttattcctct gaacgcctat gaagatgatg ttgatcctga
     1561 aacactaagc tacgctgggc aatatgttga tgattccata gctcttcaaa tagcacttgg
     1621 aaataaagat ataaatactt ttgaacagat cgatgactac aatccagaca ctgctatgcc
     1681 tgcccattca agaagtcata gttgggatga caaaacatgt caaaagtcag ctaatgttag
     1741 cagcatttgg cataggaatt actctcccag accagagtcg ggtactgttt cagatgcccc
     1801 acaattgaag gaaaatccaa gtactgtggg agtggaacga gtgattagta ctaaagggtt
     1861 aaatctccca aggaaatcat ccattgtgaa aagaccaaga agtgcagagc tgtcagaaga
     1921 tgacctgttg agtcagtatt ctctttcatt tacgaagaag accaagaaaa atagctctga
     1981 aggcaataaa tcattgagct tttctgaagt gtttgtgcct gacctggtaa atggacctac
     2041 taacaaaaag agtgtaagca ctccacctag gacgagaaat aaatttgcaa catttttaca
     2101 aaggaaaaat gaagaaagtg gtgcagttgt ggttccaggg accagaagca ggtttttttg
     2161 cagttcagat tctactgact gtgtatcaaa caaagtgagc atccagcctc tggatgaaac
     2221 tgctgtcaca gataaagaga acaatctgca tgaatcagag tatggagacc aagaaggcaa
     2281 gagactggtt gacacagatg tagcacgtaa ttcaagtgat gacattccga ataatcatat
     2341 tccaggtgat catattccag acaaggcaac agtgtttaca gatgaagagt cctactcttt
     2401 tgagagcagc aaatttacaa ggaccatttc accacccact ttgggaacac taagaagttg
     2461 ttttagttgg tctggaggtc ttggagattt ttcaagaacg ccgagcccct ctccaagcac
     2521 agcattgcag cagttccgaa gaaagagcga ttcccccacc tctttgcctg agaataatat
     2581 gtctgatgtg tcgcagttaa agagcgagga gtccagtgac gatgagtctc atcccttacg
     2641 agaagaggca tgttcttcac agtcccagga aagtggagaa ttctcactgc agagttcaaa
     2701 tgcatcaaag ctttctcagt gctctagtaa ggactctgat tcagaggaat ctgattgcaa
     2761 tattaagtta cttgacagtc aaagtgacca gacctccaag ctacgtttat ctcatttctc
     2821 aaaaaaagac acacctctaa ggaacaaggt tcctgggcta tataagtcca gttctgcaga
     2881 ctctctttct acaaccaaga tcaaacctct aggacctgcc agagccagtg ggctgagcaa
     2941 gaagccggca agcatccaga agagaaagca tcataatgcc gagaacaagc cggggttaca
     3001 gatcaaactc aatgagctct ggaaaaactt tggatttaaa aaagattctg aaaagcttcc
     3061 tccttgtaag aaacccctgt ccccagtcag agataacatc caactaactc cagaagcgga
     3121 agaggatata tttaacaaac ctgaatgtgg ccgtgttcaa agagcaatat tccagtaaat
     3181 gcagactgct gcaaagcttt tgcctgcaag agaatctgat caatttgaag tccctgtttg
     3241 ggaatgaggc acttatcagc atgaagaatt ttttctcatt ctgtgccatt ttaaaaatag
     3301 aatacatttt gtatattaac tttataattg ggttgtggtt tttttgctca gctttttata
     3361 tttttataag aagctaaata gaagaataat tgtatctctg acaggttttt ggaggtttta
     3421 gtgttaattg ggaaaatcct ctggagttta taaaagtcta ctctaaatat ttctgtaatg
     3481 ttgtcaagta gaaagatagt aaatggagaa actacaa
//
