LOCUS       NM_001145127            1979 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens envoplakin like (EVPLL), mRNA.
ACCESSION   NM_001145127 XR_040221 XR_040222 XR_040223
VERSION     NM_001145127.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC036791.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001145127.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC036791.1, AK298286.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2142586, SAMEA2145893
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000399134.5/ ENSP00000382086.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1979              BC036791.1         14-1992
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17p11.2"
     gene            1..1979
                     /gene="EVPLL"
                     /note="envoplakin like"
                     /db_xref="GeneID:645027"
                     /db_xref="HGNC:HGNC:35236"
     exon            1..206
                     /gene="EVPLL"
                     /inference="alignment:Splign:2.1.0"
     exon            207..305
                     /gene="EVPLL"
                     /inference="alignment:Splign:2.1.0"
     CDS             243..1148
                     /gene="EVPLL"
                     /codon_start=1
                     /product="envoplakin-like protein"
                     /protein_id="NP_001138599.1"
                     /db_xref="CCDS:CCDS45626.1"
                     /db_xref="GeneID:645027"
                     /db_xref="HGNC:HGNC:35236"
                     /translation="MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKE
                     AEVLLKDLFLDVDKARRLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRG
                     IQGRLGTRAGAETEAGLRRPVWAGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCR
                     HHPEPIPRPTEGGVVARAEPGQPVHALQGCTWQLSALAEQQRRILQQDWSDLMADPAG
                     VRREYEHFKQHELLSQEQSVNQLEEDGKRMVELRHPAVGPIQAHQEALKMEWQNFLNL
                     CICQETQLQHVEDYSRILCPSSSPH"
     exon            306..460
                     /gene="EVPLL"
                     /inference="alignment:Splign:2.1.0"
     exon            461..588
                     /gene="EVPLL"
                     /inference="alignment:Splign:2.1.0"
     exon            589..714
                     /gene="EVPLL"
                     /inference="alignment:Splign:2.1.0"
     exon            715..753
                     /gene="EVPLL"
                     /inference="alignment:Splign:2.1.0"
     exon            754..914
                     /gene="EVPLL"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1022
                     /gene="EVPLL"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1118
                     /gene="EVPLL"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1188
                     /gene="EVPLL"
                     /inference="alignment:Splign:2.1.0"
     exon            1189..1979
                     /gene="EVPLL"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1958..1963
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EVPLL"
                     /note="hexamer: AATAAA"
     polyA_site      1979
                     /gene="EVPLL"
                     /note="major polyA site"
ORIGIN      
        1 gccagactta gctgaccagc cagcaaggac gcccgctgcc tcccacctgc cctcctgccc
       61 tccttcacca gccaagccca gcctgagcca gcacctgcct ttatgaccat gttcaaggga
      121 ctgagcaaag gctcccaggg gaaggggtcc cccaaggact ccccagccaa ggggtccccc
      181 aaaggctccc ccagcaagca cagctgaatg ccacccagga gctgaccctg ctcatctccc
      241 acatgcaagc cagcgccgac caggtggagc gggacatcct ggagacgcag aagaggctgc
      301 agcaggaccg gctgaacagt gagcagagcc aggccctgca gcaccagcag gagacgggca
      361 gcagcctgaa ggaggccgag gtgctgctca aggacctctt cctggacgtg gacaaggccc
      421 ggcggctcaa gcacccgcag gctgaggaga ctgagaagga catcgagcag ctgcacgagc
      481 gggtgaccca ggagtgtgcg gagtactgtg ccctgtacga gaagatggtg ctgccgcccc
      541 gacgtgggat ccaaggtcga ctgggcacac gtgctggagc agaaacagaa gctggtctgc
      601 gcaggccagt atgggccggg catggcggag ctggaggaac agatcgcgga gctcaacatc
      661 gtgcagaagg agatcaacga ccaaggagag cagctgcgga gcctggtggg gccggatgcc
      721 gccaccatcc ggagccaata ccgagaccta ctgagggcgg cgtcgtggcg cgggcagagc
      781 ctgggcagcc tgtacacgca ctgcagggct gcacgtggca gctgagcgcc ctggcggagc
      841 agcagcgccg catcctgcag caggactgga gcgacctcat ggccgaccct gcgggcgtgc
      901 ggcgggaata cgagcacttc aagcagcacg agctgctgag ccaggagcag agcgtaaacc
      961 agctggagga ggacggcaag cgcatggtgg agctgcggca ccccgcggtg gggcccatcc
     1021 aggcccacca ggaggccctg aagatggagt ggcagaactt cctgaacctg tgcatctgcc
     1081 aggagaccca gctccagcac gtggaggact acagccggat tctgtgtcca tcttcctctc
     1141 ctcattgact ctgcatgaag gggatttctg gtggagtaag ggtagcagct cttgccgcac
     1201 gtgcagagag agaggaactt ccagtgcccg ctatggagcc acagcccaca gcatggggaa
     1261 gtccccatcc agaggcagtg ctgcagctag aggtagctcc agagtcctcc gggccctgca
     1321 ccgatacagc caaagaccag caaagcgaca agctgccaga cctcatgcca cctgctgtag
     1381 ccactgggct cagccctgga gctgagagca tcgctggaga tagacgtggc agagaagagg
     1441 ttgcgagcat ggccccagcc agcagctccc acgctgcccc tagtcctggg catggagcga
     1501 gccttggtgt cagagaccag ggtgtgcagt ctgagctcct ctaccttact aaagagaggc
     1561 ctcttttatt taccagagcc acagccctgc tgcctcagga ccttttcatt ctgccggtgc
     1621 tggggctgtc tatctgcaag ctggaggtgt tgagagcagg aaaaggaggc tgtgaggaag
     1681 ggttcgggca gctcctcctg ctctcagagg tggcctcctc ctccaggcat ggaggtctgt
     1741 ccactactgg gcttctgggc tatttgcccc tgatttgctc cctggtacgg gctcttctta
     1801 acaggcaggc aaggggtgcg gggaccaggt gagggcttca aagggtacag taccaaatct
     1861 tccaaactca gcacttgtgc cctggggtct ccaaactgtc ttctgcccta gaatttattc
     1921 atactgttaa attaccagtt tatgcaaatg atatgtaaat aaagctcaat tttttgaaa
//
