LOCUS       NM_001004341            1977 bp    mRNA    linear   PRI 21-FEB-2025
DEFINITION  Homo sapiens ETS variant transcription factor 3 like (ETV3L), mRNA.
ACCESSION   NM_001004341 XM_496419
VERSION     NM_001004341.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1977)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1977)
  AUTHORS   Anney,R.J., Lasky-Su,J., O'Dushlaine,C., Kenny,E., Neale,B.M.,
            Mulligan,A., Franke,B., Zhou,K., Chen,W., Christiansen,H.,
            Arias-Vasquez,A., Banaschewski,T., Buitelaar,J., Ebstein,R.,
            Miranda,A., Mulas,F., Oades,R.D., Roeyers,H., Rothenberger,A.,
            Sergeant,J., Sonuga-Barke,E., Steinhausen,H., Asherson,P.,
            Faraone,S.V. and Gill,M.
  TITLE     Conduct disorder and ADHD: evaluation of conduct problems as a
            categorical and quantitative trait in the international multicentre
            ADHD genetics study
  JOURNAL   Am J Med Genet B Neuropsychiatr Genet 147B (8), 1369-1378 (2008)
   PUBMED   18951430
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK131392.1, AL157713.10 and AA723297.1.
            
            On Jan 28, 2010 this sequence version replaced NM_001004341.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK131392.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000454449.3/ ENSP00000430271.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1115              AK131392.1         1-1115
            1116-1565           AL157713.10        89988-90437         c
            1566-1977           AA723297.1         2-413               c
FEATURES             Location/Qualifiers
     source          1..1977
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q23.1"
     gene            1..1977
                     /gene="ETV3L"
                     /note="ETS variant transcription factor 3 like"
                     /db_xref="GeneID:440695"
                     /db_xref="HGNC:HGNC:33834"
                     /db_xref="MIM:621105"
     exon            1..343
                     /gene="ETV3L"
                     /inference="alignment:Splign:2.1.0"
     CDS             286..1371
                     /gene="ETV3L"
                     /note="ets variant gene 3-like; ets variant 3-like; ETS
                     variant 3 like"
                     /codon_start=1
                     /product="ETS translocation variant 3-like protein"
                     /protein_id="NP_001004341.1"
                     /db_xref="CCDS:CCDS30893.1"
                     /db_xref="GeneID:440695"
                     /db_xref="HGNC:HGNC:33834"
                     /db_xref="MIM:621105"
                     /translation="MHCSCLAEGIPANPGNWISGLAFPDWAYKAESSPGSRQIQLWHF
                     ILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYY
                     NKRILHKTKGKRFTYKFNFSKLIVVNYPLWEVRAPPSPHLLLGAPALCRPALVPVGVQ
                     SELLHSMLFAHQAMVEQLTGQQTPRGPPETSGDKKGSSSSVYRLGSAPGPCRLGLCCH
                     LGSVQGELPGVASFTPPLPPPLPSNWTCLSGPFLPPLPSEQQLPGAFKPDILLPGPRS
                     LPGAWHFPGLPLLAGLGQGAGERLWLLSLRPEGLEVKPAPMMEAKGGLDPREVFCPET
                     RRLKTGEESLTSPNLENLKAVWPLDPP"
     exon            344..581
                     /gene="ETV3L"
                     /inference="alignment:Splign:2.1.0"
     exon            582..771
                     /gene="ETV3L"
                     /inference="alignment:Splign:2.1.0"
     exon            772..892
                     /gene="ETV3L"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1977
                     /gene="ETV3L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1954..1959
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ETV3L"
                     /note="hexamer: AATAAA"
     polyA_site      1977
                     /gene="ETV3L"
                     /note="major polyA site"
ORIGIN      
        1 gtccgagtca gccctgggca gcggggaggt ccccagaggg ggctgggccc tgtctgggta
       61 tggggaagct tgctgcctct ggttcccttt tctccccttc actggcaacc tcttgtccct
      121 tcccttttct ctctttcttt cctgaccctc tcccttcctt ccttctttcc ctccattttt
      181 ccttcctctt tcactgtcct cccctctgcc tccttccttc ccttcctctt aagtggtgac
      241 catttcccca aggcccagac acagcccatc tcgccggagt ggaccatgca ctgcagctgc
      301 ttggctgagg gcatcccagc caaccccggc aactggatct cagggttggc cttccctgat
      361 tgggcctaca aagccgagtc gtccccaggc tcccggcaga tccagctgtg gcacttcatc
      421 ctggagctgc tgcagaagga agagttccgc catgtcatcg cctggcagca gggagagtac
      481 ggggaatttg tcatcaagga tccagatgag gtggcccgcc tctggggccg caggaaatgc
      541 aaaccacaga tgaattatga caagctgagc cgggccctca gatattacta caataagagg
      601 atcctgcata agaccaaagg caaaaggttc acatacaagt tcaacttcag caagctcatc
      661 gtagtcaact atcctttgtg ggaagtgcgg gcgccgccat ccccccactt gctgctgggg
      721 gcccctgccc tgtgtcggcc agcgctggtg cccgtgggtg tgcagagtga gctcctgcac
      781 agcatgctat ttgcccatca ggccatggtg gagcagctga caggacagca gaccccccga
      841 gggccaccag agacctctgg ggataagaag gggagcagca gcagcgtcta ccgacttggc
      901 tctgccccag gcccctgccg gctgggcctt tgctgccatt tggggagcgt ccaaggcgag
      961 ctgcctggtg ttgcctcctt cactcctccc ctcccgcccc ctctgccctc caactggacc
     1021 tgtctctcgg ggcccttctt gcctcctctc ccgtcagagc agcagctccc aggggctttt
     1081 aagccagaca tcctgctccc aggacctagg agcctcccag gggcctggca ttttccaggg
     1141 cttcctctct tggcagggct gggacagggt gcgggtgaga ggctttggct cttgtccctc
     1201 aggcccgagg ggctggaagt aaagcctgct cccatgatgg aggcaaaggg aggcctggat
     1261 cccagggagg tcttctgccc agagacccgc agactcaaaa ctggggagga aagccttact
     1321 tcccccaatc tggagaacct caaagcagtg tggcccttgg atcctcctta actagagagg
     1381 aaggtgggaa gttggggagg agtcctccaa agtccatctc tcctcttgcc caccgcctct
     1441 gggttagccc cttcccctgg ctggacatgg gctgaaattg caggatttga aggggtggag
     1501 ttggacccaa ggtggggagc attgcaggga aggtgtgaat gtggaaatgg gaaaaaccaa
     1561 gacagggtgc ccctcctctt tcaccatatt gctaagcaga ctaaggggac attcctaatc
     1621 tcaacttttc ttcagggaga cgagaataaa gtttctataa tttccatcct gcccacataa
     1681 gggggaaaat taagggtcta gcctggggag aggacagggg tggttgtgtt ccctgagtct
     1741 tgtctggggc ccatctcccc attccaggct aaggtctcca gtccctttct cacccctcca
     1801 tgcaacttct ctcccatccc tctgatttct gagaccctgg aaacccctgt cccatgcagg
     1861 cacttcctcc tctctccatt tccccaggac ccaggcaagt ggggtgggga gacactggcc
     1921 ttctctgctc tgtaatactc cactgtgacc atgaataaaa tgcccttgca aactgtc
//
