LOCUS       XM_011536553            4736 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens estrogen related receptor beta (ESRRB),
            transcript variant X4, mRNA.
ACCESSION   XM_011536553
VERSION     XM_011536553.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011536553.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4736
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..4736
                     /gene="ESRRB"
                     /gene_synonym="DFNB35; ERR beta-2; ERR2; ERRb; ERRbeta2;
                     ESRL2; NR3B2"
                     /note="estrogen related receptor beta; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 7 ESTs, 7 long SRA reads, 4 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 1 sample with support for all
                     annotated introns"
                     /db_xref="GeneID:2103"
                     /db_xref="HGNC:HGNC:3473"
                     /db_xref="MIM:602167"
     CDS             266..1861
                     /gene="ESRRB"
                     /gene_synonym="DFNB35; ERR beta-2; ERR2; ERRb; ERRbeta2;
                     ESRL2; NR3B2"
                     /codon_start=1
                     /product="steroid hormone receptor ERR2 isoform X3"
                     /protein_id="XP_011534855.1"
                     /db_xref="GeneID:2103"
                     /db_xref="HGNC:HGNC:3473"
                     /db_xref="MIM:602167"
                     /translation="MDVSELCIPDPLGYHNQLLNRMSSDDRHLGSSCGSFIKTEPSSP
                     SSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCAS
                     GIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSC
                     PATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYL
                     SLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVII
                     GWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSR
                     LAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLH
                     EALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEML
                     EAKAWARADSLQEWRPLEQVPSPLHRATKRQHVHFLTPLPPPPSVAWVGTAQAGYHLE
                     VFLPQRAGTQGTTVSFFQRSYLL"
     polyA_site      4736
                     /gene="ESRRB"
                     /gene_synonym="DFNB35; ERR beta-2; ERR2; ERRb; ERRbeta2;
                     ESRL2; NR3B2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 aagtctcttg tgccccagcc tcctccacgg cttcgcatcc cctctgcccg ctctctccgg
       61 agcgtgcgga tgagtggaga gctgggctgt gcgcgcacgg ctctctgcct ccctctcccc
      121 cgccgcggcc gcctcctccc actctgcgtt ctcgcgctca ctgtgccctg cccgggctcg
      181 caccttgccc gtgcccttca ctcgctcttc cgcgtgattt ccccgccgtc tttctctacc
      241 aactgggaat gctaaaacgg gactgatgga cgtgtccgaa ctctgcatcc cggaccccct
      301 cggctaccac aaccagctgc tgaacaggat gtcctcggac gacaggcacc tgggctccag
      361 ctgcggctcc ttcatcaaga ctgagccgtc cagcccgtcc tcgggcatcg atgccctcag
      421 ccaccacagc cccagtggct cgtccgacgc cagcggcggc tttggcctgg ccctgggcac
      481 ccacgccaac ggtctggact cgccacccat gtttgcaggc gccgggctgg gaggcacccc
      541 atgccgcaag agctacgagg actgtgccag cggcatcatg gaggactcgg ccatcaagtg
      601 cgagtacatg ctcaacgcca tccccaagcg cctgtgcctc gtgtgcgggg acattgcctc
      661 tggctaccac tacggcgtgg cctcctgcga ggcttgcaag gccttcttca agaggactat
      721 ccaagggaac attgagtaca gctgcccggc caccaacgag tgcgagatca ccaaacggag
      781 gcgcaagtcc tgccaggcct gccgcttcat gaaatgcctc aaagtgggga tgctgaagga
      841 aggtgtgcgc cttgatcgag tgcgtggagg ccgtcagaaa tacaagcgac ggctggactc
      901 agagagcagc ccatacctga gcttacaaat ttctccacct gctaaaaagc cattgaccaa
      961 gattgtctca tacctactgg tggctgagcc ggacaagctc tatgccatgc ctccccctgg
     1021 tatgcctgag ggggacatca aggccctgac cactctctgt gacctggcag accgagagct
     1081 tgtggtcatc attggctggg ccaagcacat cccaggcttc tcaagcctct ccctggggga
     1141 ccagatgagc ctgctgcaga gtgcctggat ggaaatcctc atcctgggca tcgtgtaccg
     1201 ctcgctgccc tatgacgaca agctggtgta cgctgaggac tacatcatgg atgaggagca
     1261 ctcccgcctc gcggggctgc tggagctcta ccgggccatc ctgcagctgg tacgcaggta
     1321 caagaagctc aaggtggaga aggaggagtt tgtgacgctc aaggccctgg ccctcgccaa
     1381 ctccgattcc atgtacatcg aggatctaga ggctgtccag aagctgcagg acctgctgca
     1441 cgaggcactg caggactacg agctgagcca gcgccatgag gagccctgga ggacgggcaa
     1501 gctgctgctg acactgccgc tgctgcggca gacggccgcc aaggccgtgc agcacttcta
     1561 tagcgtcaaa ctgcagggca aagtgcccat gcacaaactc ttcctggaga tgctggaggc
     1621 caaggcctgg gccagggctg actcccttca ggagtggagg ccactggagc aagtgccctc
     1681 tcccctccac cgagccacca agaggcagca tgtgcatttc ctaactccct tgccccctcc
     1741 cccatctgtg gcctgggtgg gcactgctca ggctggatac cacctggagg ttttccttcc
     1801 gcagagggca ggtacgcaag ggacaacagt atctttcttc cagaggtcct acctgctctg
     1861 agatcctctg gggccggtca agaggcccca taccttccac agtttccact cagctttcag
     1921 ccagggggta cccacaggag agcagcggct agagctcaag tgcttcctgg gcaccccacc
     1981 cctcggggcc tacccccctg cctgtcaccc accgcgccgg tgtccacctg tcctcctcct
     2041 cttctcctcc ccccgggagt cccccgctac ttcctgaccc tacctcagag ctcactcacc
     2101 cagtgggttc agccagccac agcgactcca ggggctgtag acaggaacgc gctggcacag
     2161 agaagagcgg ggaccacacc atcctcccaa gaaccctctc cctcttcctg ccttccccct
     2221 ctccctgaag ggcaggtcca ggccaagtga gcctgtgaga agctcaggag cctggctcca
     2281 tccaagagca ccccgggggg aggatcagga caggatggac agaggcccag actcatcttt
     2341 gccaagcaca gaaaggccga gcagctgaga taagtaggca ggggagcccc aaagggaggg
     2401 aactcagcgg ggtggcctgc ctcatccttc ctggcttccc ttccctgcac tcagcatcat
     2461 gccacagggc tagtgtacca gtgccacagg aggggtgccc tcctaccaca cttgggctac
     2521 cagaggtttg gtgtagctcc cctgggcacc gcgagcacgc cagctctctg gcaggacccc
     2581 tgcagtcccc ctggctgtgc caggtaacca accgtcttgg tttgtccagg acgtttcttt
     2641 atcccaggaa actcctctac cccaggcaca cggggacagt gggtcactct atttctgtgg
     2701 atggccgtga aagttttcac taactcaagg ggcagccctg aacacccatt tgtgctcaca
     2761 ggttggccaa gagcagctta gaggatctcc caaggatgaa agaatgtcaa gccatgatgg
     2821 aaaatgcccc ttccaatcag ctgccttcac aagcagggat cagagcaact ccccggggat
     2881 ccccaatcca cgcccttcta gtccaacccc cctcaatgag agaggcaggc agatctcacc
     2941 cagcactagg acaccaggag gccaggtaac tttctgcagc ttttccatag aagccctggt
     3001 cccacctcct tggctctacc ccaggaacct cccggcctgg gcttctgggc tgggacgtgc
     3061 tgaggtcatc ccagacagga gggagggctg gctgaaatcc acaaactgca gagcagctct
     3121 ctgatggtgt cccacacaga aaatgttaag gatttcaaga gccctcccag accagtgatg
     3181 tgtccctccg gctccccttg cctgtgggga atcgggtctg agtcacttga tgagtaggca
     3241 ctggagccgt tacccaggat gctgcggccc tagccctcca tgcagcccat cttccctcat
     3301 ttgggtggag gcacacattt ggggcaaagg ccccttcttg gcatcaagga acaccagcta
     3361 caaaccaagt ctagcacagt gtttagaggc tctgccctga ggttctgctc cggagaaacc
     3421 ttcacagtag agaccttggg gtgtgtgctt tgggactccc tcagtctctc actgtgctgt
     3481 gtccttgcag cggggccgag gtagcaccct gctctgtcac ttcctgctca agctggagga
     3541 cccaggcggc agggcatcat gcccagctgg catctgctgt ctgtcttttc tagggaaagc
     3601 atctctggct caccatgtaa catctggctt ggagcaagtg ggtgttctgc acaccaggca
     3661 gctgcacctc actggatcta gtgttgctgc gagtgacctc acttcagagc ccctctagca
     3721 gagtggggcg gaagtcctga tggttggtgt ccatgaggtg gaagctgctt ttatacttaa
     3781 aactcagatc acaacaggaa atgtgtcagt aacaatggaa ctccatccaa tgggaaagtt
     3841 cctggtactg aaggggtcca ttggacactc agaaaagaag ttcaggggcc aacttcttag
     3901 ctggaatcct ggccagatga ggaccctctc cggggaaggg agaggactga cttagtggaa
     3961 ggtggtgaag tgaggagagt ttaggggaac cttcccccag tggaacagat ctcaagttta
     4021 ccctaaacct gccatttctg gaaaatctgt aaagaggaaa cagcctgtct cagctgtact
     4081 ctcatgatac aggtcatttg aaatgaacca agaaataaaa catgaaaatc caaccatgga
     4141 gaaggtggta tggctgggtt ttgtttggtc cccttgtcct tatacgttct aaagtttcca
     4201 gactggcttt gtcactttgt gaactcgtca tgtgtgaaaa ccaatctttg catataggga
     4261 acttcctcgg gccacacttt aagaaccaag taagaggctc tcaagactcc agcagagtcg
     4321 ggaggccatg gcagcgcctt agaggagctg gaacctgcac ccacctgtgt cggtgggggg
     4381 ggcctccttt ccccatagac tctgccctcc ctctgtgcag atggaagtgg caggggaggg
     4441 tgaccagctt gtgacaagaa gactgaaggg tccagagtcc atgctcacgg aacagcacca
     4501 aagaaaagca ctatgtggaa agattgtttt attttctaat aatgataata tggctggaat
     4561 ggcttcttaa gatgtatata ttttttaaaa tggcagttcc ccattgcagc atcacctact
     4621 tgtatgtctt tctgcctctg tatatgttct cccagaaacc cccatgtaaa tcaaatgccc
     4681 taggatgctt ccatcctggt cccatgtatc tggaatctaa taaataagga aaggaa
//
