LOCUS       XM_047431551            3128 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens espin (ESPN), transcript variant X7, mRNA.
ACCESSION   XM_047431551
VERSION     XM_047431551.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3128
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..3128
                     /gene="ESPN"
                     /gene_synonym="DFNB36; LP2654; USH1M"
                     /note="espin; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 4 ESTs, 15 long SRA reads, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 10 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:83715"
                     /db_xref="HGNC:HGNC:13281"
                     /db_xref="MIM:606351"
     CDS             237..2654
                     /gene="ESPN"
                     /gene_synonym="DFNB36; LP2654; USH1M"
                     /codon_start=1
                     /product="espin isoform X6"
                     /protein_id="XP_047287507.1"
                     /db_xref="GeneID:83715"
                     /db_xref="HGNC:HGNC:13281"
                     /db_xref="MIM:606351"
                     /translation="MAHSEEAALLPGNHVPNGCAADPKASRELPPPPPPPPPPLPEAA
                     SSPPPAPPLPLESAGPGCGQRRSSSSTGKVRVLRHRKSTKSFNMMSPTGDNSELLAEI
                     KAGKSLKPTPQSKGLTTVFSGIGQPAFQPDSPLPSVSPALSPVRSPTPPAAGFQPLLN
                     GSLVPVPPTTPAPGVQLDVEALIPTHDEQGRPIPEWKRQVMVRKMQLKMQEEEEQRRK
                     LTAASSCCYPREGWRYSREHNAILGPFGELMTEADILRIEQQIENLQVLHKAQKLEAR
                     LEQLELELEQLLPISAALSAPRFTVDPRRMHGRAASLPAWCSKISTLLKNMATLLAAL
                     GGRPAHLAELLTADTGQPLAPLPDAPWLPGPLCLGRSHSLSWCREAVAREILECGVSV
                     QHLRATYELRARGAAPARCPRRKPPQSAGAPGREPILEEDYVAARSGQPSAAAAHGPL
                     VDWEPLGTLGPPEVQDRQAALPEPEQLARRPPLCTKLRGVQDYLDLRKERIVYLFLEH
                     WRRWACRGPGRRAQARLRGLLPRVAAAGAGPGLEATDAPRLPASNSEAHSPDERLRQL
                     LRQRQAVGKLLGHWRSLLRRVPASPGLAHGLYWPQHFLPPLDGGAPPHYDSLTLDLFM
                     LGYFQLLEMGLSREERKFRHLLCYEMFDRLGSHPWERIRLFHRVVLEEVEAGRRGWSD
                     GFEDLRHRFFGNGLEAEPAPEEQAKEKEEEGKEQERTEEAAPFQTGDPPEGQPEALAP
                     APQPPPPPPPAAPPPTSDSPGSEAPAEDPLELVSEMGEFSNEDICRYIDRSFSFWKEK
                     EAELFDI"
     polyA_site      3128
                     /gene="ESPN"
                     /gene_synonym="DFNB36; LP2654; USH1M"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gaccctcgcc cgctgcccac tgtgagaacc agggggtcta ggaagtcagc tgctgcaccc
       61 ctcgacggcc gctggccgcg agtccccagg agctgagctc ctgtgacggc cacgacgggc
      121 tgcggaggca ggactccagc cgcaagcccc gcgccttcag caagcagccc agcacggggg
      181 actactaccg gcagctgggc cgctgccccg gcgagacgct ggccgcacgc ccgggcatgg
      241 cgcacagcga ggaggcggcg ctgcttcctg ggaaccatgt tcctaacggc tgcgccgcgg
      301 accccaaggc gtccagggag ctgccaccgc cgcccccacc gccgccgccg cccctgccgg
      361 aggccgcgag ttcgccaccg ccggccccgc ctctgcccct cgagagcgct ggccctggct
      421 gcgggcagcg ccgctcctcc tcgtccaccg gcaaagtgag agtcctgagg cacaggaaga
      481 gcaccaagtc tttcaacatg atgtccccga cgggcgacaa ctcggagcta ctggctgaga
      541 ttaaggcagg caagagcctg aagccgacgc cccagagcaa ggggctgacc acagtgttct
      601 caggcatcgg gcagccggcc ttccagcccg attcgccgct gccttctgtg tcacctgcac
      661 tgtcaccagt ccggagcccc acaccgccag ctgcggggtt tcagccgctg ctcaatggaa
      721 gcttggttcc cgtgccgccc actactcctg cgccgggagt gcagctggac gtggaggctc
      781 tcatccccac gcacgatgag cagggccggc ccatccccga gtggaagcgc caggtgatgg
      841 tgcgcaagat gcagctgaag atgcaggagg aggaggagca gaggcggaag ctgacggccg
      901 ccagctcgtg ctgctacccc cgcgagggct ggaggtactc ccgcgagcac aacgccatcc
      961 tcgggccctt tggcgagctt atgaccgaag ccgacatcct ccgcatcgag cagcaaatcg
     1021 agaacctgca ggtgctgcac aaggcgcaga agctggaggc gcgcctcgag caactggagc
     1081 tggagctgga gcagctgctg cccatctcgg ccgccctgtc ggcgccgcgc ttcaccgtcg
     1141 atccgcgccg aatgcatggc cgcgccgcca gcctgcccgc ctggtgcagc aagatctcca
     1201 cgttgctcaa gaacatggcc acgctgctgg ctgcgctggg cggccggcct gcgcacctgg
     1261 cggagctgct gaccgctgac acgggccagc cgctggcgcc gctgcccgac gcgccctggc
     1321 tgcccgggcc gctctgcctg ggtcgctcgc actcgctcag ctggtgccgc gaggctgtgg
     1381 cgcgcgagat cctcgagtgc ggcgtctccg tgcagcatct ccgcgccacc tacgagctgc
     1441 gcgcacgggg cgcggcgccc gcgcgctgtc cgcgccgcaa gcccccgcag tccgctggcg
     1501 ccccgggccg ggagcccatc ttggaggagg actacgtggc ggcccgctct ggccagccca
     1561 gcgccgccgc cgcccacggc ccgctggtcg actgggagcc cctgggcacc ctgggcccgc
     1621 ccgaggtaca ggatcgccag gcggcgctgc ctgagcccga gcagctggcg cgccggccgc
     1681 ccctctgcac gaagctgcgc ggcgtccagg actacctcga cctgcgcaag gagcgcatcg
     1741 tttacctctt cctggagcac tggcgccgct gggcctgccg cggaccaggc cgccgcgccc
     1801 aggcgcgcct acgcggactg ctgccccgcg tggcggctgc cggtgctggc ccggggctgg
     1861 aggccacgga cgccccccgg ctgccggcga gcaacagcga ggcccacagc cccgacgaac
     1921 ggctgcggca gctgctgagg cagcggcagg cggtgggcaa gctgctgggc cactggcgga
     1981 gcctgctgcg tcgcgtgccg gcaagcccgg gcctggcgca cggcctgtat tggccccagc
     2041 acttcctgcc gcccctggac ggcggcgcac ccccgcacta cgacagcctc acgctcgacc
     2101 tcttcatgct cggctacttc cagctactcg agatgggcct gagccgcgag gagcgcaagt
     2161 tccgccacct actgtgctac gagatgttcg accgactggg cagccacccg tgggagcgca
     2221 tccgcctctt ccaccgcgtg gtgctggagg aggtggaggc cggccggcgc ggctggagcg
     2281 acggcttcga ggacctcagg caccggttct tcggaaacgg cctggaggct gagccggccc
     2341 ccgaagaaca ggcgaaggaa aaggaagagg aggggaaaga acaggagcgg accgaagagg
     2401 ctgctccatt tcagacgggg gacccgcctg aggggcagcc cgaggccctg gcccctgcgc
     2461 cgcagccgcc gccgccgccc ccgcccgccg cgcctccccc gacctcagac tctcctggtt
     2521 ccgaagcccc cgccgaagac cccttggaac tggtgtctga gatgggcgag ttcagcaacg
     2581 aggacatctg ccgctacatc gaccgcagct tctccttctg gaaagagaag gaggcagagc
     2641 tgtttgacat ctgagcagcg gaattcggaa ttctcagttc accctcgagc gtcttaacgt
     2701 gggcctggac gcctgtctga cgccctccag aggctggaag cagcaggaag agcccaggac
     2761 tgtggccttg agcagcccgg agggcccagg accaggctgc ctcagcctct gaggtcccat
     2821 cgtggcgggc tgtggggcgt tggtcggata ggcagggcag gcacagaaca gaccaggtgt
     2881 ccgcctctgg ccccgtggcc ttgctgagct ctgtgtggag ccaggcagca gaagaagccc
     2941 ctctgagtga ggggctgcgg ctcctccttg cggcagtgtg gcctgctctt tggttttcca
     3001 ctggagttca cagctacctc cttggctgag gtcaagggtg ccacgtgtgc agtgttctgt
     3061 gtgaagtgtg ccgtgtacag acccgttctc ctctgtaaca ttcaggaaat aaaactcttt
     3121 gctgtaaa
//
