LOCUS       NM_182542               2424 bp    mRNA    linear   PRI 03-AUG-2024
DEFINITION  Homo sapiens glutamate rich 6B (ERICH6B), mRNA.
ACCESSION   NM_182542 XM_001719972 XM_495949 XM_942284
VERSION     NM_182542.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2424)
  AUTHORS   Rose,J.E., Behm,F.M., Drgon,T., Johnson,C. and Uhl,G.R.
  TITLE     Personalized smoking cessation: interactions between nicotine dose,
            dependence and quit-success genotype score
  JOURNAL   Mol Med 16 (7-8), 247-253 (2010)
   PUBMED   20379614
  REMARK    GeneRIF: Clinical trial of gene-disease association and
            gene-environment interaction. (HuGE Navigator)
            Erratum:[Mol Med. 2012;18(1):729]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL139326.15.
            
            On May 17, 2019 this sequence version replaced NM_182542.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK057244.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1968968,
                                           SAMEA2144333 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000298738.3/ ENSP00000298738.2
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                AL139326.15        148442-148496       c
            56-107              AL139326.15        140321-140372       c
            108-802             AL139326.15        129126-129820       c
            803-851             AL139326.15        123406-123454       c
            852-1021            AL139326.15        119820-119989       c
            1022-1084           AL139326.15        113360-113422       c
            1085-1126           AL139326.15        112690-112731       c
            1127-1215           AL139326.15        107599-107687       c
            1216-1352           AL139326.15        101072-101208       c
            1353-1414           AL139326.15        96484-96545         c
            1415-1572           AL139326.15        94126-94283         c
            1573-1658           AL139326.15        82988-83073         c
            1659-1811           AL139326.15        82650-82802         c
            1812-2037           AL139326.15        77517-77742         c
            2038-2421           AL139326.15        74054-74437         c
            2422-2424           AL139326.15        74051-74053         c
FEATURES             Location/Qualifiers
     source          1..2424
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q14.13"
     gene            1..2424
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /note="glutamate rich 6B"
                     /db_xref="GeneID:220081"
                     /db_xref="HGNC:HGNC:26523"
     exon            1..55
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            56..107
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            108..802
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     CDS             166..2256
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /note="protein FAM194B; family with sequence similarity
                     194, member B"
                     /codon_start=1
                     /product="glutamate-rich protein 6B"
                     /protein_id="NP_872348.2"
                     /db_xref="CCDS:CCDS45045.1"
                     /db_xref="GeneID:220081"
                     /db_xref="HGNC:HGNC:26523"
                     /translation="MSAENNQLSGASPPHPPTTPQYSTQNLPSEKEDTEVELDEESLQ
                     DESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAG
                     YLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVDYLGK
                     KAYLEEEEYLGKKSYLEEEKALEKEENLEEEEALEKEENLDGKENLYKKYLKEPKASY
                     SSQTMLLRDARSPDAGPSQVTTFLTVPLTFATPSPVSESATESSELLLTLYRRSQASQ
                     TDWCYDRTAVKSLKSKSETEQETTTKLAPEEHVNTKVQQKKEENVLEFASKENFWDGI
                     TDESIDKLEVEDLDENFLNSSYQTVFKTIIKEMAAHNELEEDFDIPLTKLLESENRWK
                     LVIMLKKNYEKFKETILRIKRRREAQKLTEMTSFTFHLMSKPTPEKPETEEIQKPQRV
                     VHHRKKLERDKEWIQKKTVVHQGDGKLILYPNKNVYQILFPDGTGQIHYPSGNLAMLI
                     LYAKMKKFTYIILEDSLEGRIRALINNSGNATFYDENSDIWLNLSSNLGYYFPKDKRQ
                     KAWNWWNLNIHVHAPPVQPISLKINEYIQVQIRSQDKIIFCFTYEQKQICLNLGTRYK
                     FVIPEVLSEMKKKTILEAEPGPTAQKIRVLLGKMNRLLNYATTPDLENFIEAVSISLM
                     DNKYLKKMLSKLWF"
     exon            803..851
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            852..1021
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1084
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1126
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1215
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1352
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            1353..1414
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            1415..1572
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1658
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            1659..1811
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            1812..2037
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
     exon            2038..2424
                     /gene="ERICH6B"
                     /gene_synonym="FAM194B"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacaaacgcc ggggcctgag atcgcggtgg atgcacgcgc gggagcctgg cttggctgtt
       61 attgttgaaa actctcttgg cttggactca gtttaccccc tgacattgat aataaagtga
      121 cgttggctgc tgcagaagga gttcaccacc tacgacttcc ccagcatgtc tgctgaaaat
      181 aatcagttat caggagcatc acctcctcac cctcccacaa ctccccaata ttccacacag
      241 aacttgcctt cagagaaaga ggatactgaa gtagaactag atgaggaaag tctacaggat
      301 gaatctccat tttctccaga gggagagtct ctggaggaca aagagtatct ggaggaggaa
      361 gaggatctgg aagaggaaga gtatctgggg aaagaagaat acttgaagga ggaagagtat
      421 ctggggaagg aagagcatct ggaggaggaa gagtatctgg agaaggcagg gtatctggag
      481 gaggaagagt atattgaaga ggaagagtat ctggggaagg aagggtatct ggaggaggaa
      541 gagtacctgg ggaaggaaga gcatctggag gaggaagagt atctggggaa ggaagggtat
      601 ctggagaagg aagattatat tgaggaggta gattatctgg ggaagaaagc gtatctggag
      661 gaggaggagt atctggggaa gaaatcatat ctagaagagg aaaaggctct ggagaaggaa
      721 gagaatctgg aggaggaaga agctctggag aaggaagaga atctggatgg aaaagaaaat
      781 ctgtataaaa agtatctgaa agaacccaag gcaagttatt catcacaaac catgcttctt
      841 cgtgatgcaa ggagtccaga cgctggcccc tctcaggtga ccaccttctt gactgtcccg
      901 ttgactttcg ctaccccttc tcctgtctct gaatctgcca cagagtcttc tgagttgctt
      961 ctgacattgt acaggaggag ccaggccagt cagacagact ggtgctacga cagaactgcc
     1021 gtaaaatctt taaaatcgaa atcagaaaca gagcaagaaa ccaccacgaa gctggctccg
     1081 gaagagcatg ttaacactaa agtacagcaa aaaaaggaag aaaatgtcct ggagtttgct
     1141 tctaaagaga acttttggga tggtataaca gatgagtcca ttgacaagct ggaagtggaa
     1201 gatttagatg aaaacttttt gaacagctcc tatcagacag tatttaaaac aataatcaaa
     1261 gaaatggctg ctcacaatga actggaagag gattttgaca ttcccctaac taagctactg
     1321 gaaagtgaaa acagatggaa actggtaatt atgctgaaga aaaattatga aaagttcaag
     1381 gaaacaatct tacggattaa gaggagacgt gaagctcaaa agttaacaga gatgaccagt
     1441 ttcacatttc atttaatgag caaaccaaca cctgagaagc ctgagacaga agaaatccaa
     1501 aagcctcaac gtgttgttca tcataggaag aaattagaac gagataagga atggatacag
     1561 aagaagacag tggtgcatca aggtgatgga aaattaattc tctaccccaa caagaatgtc
     1621 tatcaaattc tctttcctga tgggacaggc cagatacatt atccatcagg aaacctggct
     1681 atgctcatct tatatgcgaa aatgaaaaag ttcacataca tcattctgga agacagtcta
     1741 gaagggagga tccgggccct tatcaacaac tcaggcaatg ctaccttcta tgatgaaaat
     1801 agtgatatct ggttgaacct gagctccaac ctgggctact acttccccaa agacaaacgc
     1861 cagaaggcct ggaactggtg gaatctgaac atccatgtcc acgcaccccc tgtccagccc
     1921 atctccttga aaatcaatga gtacatccag gtacaaataa ggagccagga taagatcatc
     1981 ttctgcttca cctatgaaca gaagcagatt tgtttaaacc tgggcaccag gtacaagttt
     2041 gtgatcccag aggtgctgag cgaaatgaag aagaaaacca tcctggaggc agaacccggc
     2101 ccaacagccc agaagatccg ggtccttctg gggaaaatga ataggctcct gaattacgcg
     2161 accacccctg atctggaaaa cttcatagag gccgtcagta tatcactgat ggacaacaag
     2221 tacctgaaga agatgctctc taaactctgg ttttaaggcg gggcttatct ggcatccacc
     2281 aaatgcctta ggaagttgga gaccttggga gctccaggga aaaaaaaccc aaagacctgt
     2341 tgacctttta tgagagttgg tttgtaattt gggacctgtc gtggctcctt gatttgaagt
     2401 aaacattttt ggcagaaggg ctaa
//
