LOCUS       NM_001130514             948 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens glutamate rich 4 (ERICH4), mRNA.
ACCESSION   NM_001130514
VERSION     NM_001130514.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 948)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 948)
  AUTHORS   Grimwood,J., Gordon,L.A., Olsen,A., Terry,A., Schmutz,J.,
            Lamerdin,J., Hellsten,U., Goodstein,D., Couronne,O.,
            Tran-Gyamfi,M., Aerts,A., Altherr,M., Ashworth,L., Bajorek,E.,
            Black,S., Branscomb,E., Caenepeel,S., Carrano,A., Caoile,C.,
            Chan,Y.M., Christensen,M., Cleland,C.A., Copeland,A., Dalin,E.,
            Dehal,P., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Garcia,C., Georgescu,A.M., Glavina,T., Gomez,M.,
            Gonzales,E., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Ho,I.,
            Huang,W., Israni,S., Jett,J., Kadner,K., Kimball,H., Kobayashi,A.,
            Larionov,V., Leem,S.H., Lopez,F., Lou,Y., Lowry,S., Malfatti,S.,
            Martinez,D., McCready,P., Medina,C., Morgan,J., Nelson,K.,
            Nolan,M., Ovcharenko,I., Pitluck,S., Pollard,M., Popkie,A.P.,
            Predki,P., Quan,G., Ramirez,L., Rash,S., Retterer,J., Rodriguez,A.,
            Rogers,S., Salamov,A., Salazar,A., She,X., Smith,D., Slezak,T.,
            Solovyev,V., Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N.,
            Wagner,M., Wheeler,J., Wu,K., Xie,G., Yang,J., Dubchak,I.,
            Furey,T.S., DeJong,P., Dickson,M., Gordon,D., Eichler,E.E.,
            Pennacchio,L.A., Richardson,P., Stubbs,L., Rokhsar,D.S.,
            Myers,R.M., Rubin,E.M. and Lucas,S.M.
  TITLE     The DNA sequence and biology of human chromosome 19
  JOURNAL   Nature 428 (6982), 529-535 (2004)
   PUBMED   15057824
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC011526.7.
            
            On May 17, 2019 this sequence version replaced NM_001130514.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            CCDS Note: This CCDS representation has an inferred exon
            combination due to a lack of full-length human transcript support
            for this gene. The represented two-exon structure is supported by
            orthologous mouse transcript alignments, and by partial human
            transcript data for the 3' exon.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR279858.1021.1, ERR279842.1309.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1970526, SAMEA2142680
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000378187.3/ ENSP00000367429.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               AC011526.7         15545-15732         c
            189-948             AC011526.7         14123-14882         c
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.2"
     gene            1..948
                     /gene="ERICH4"
                     /gene_synonym="C19orf69"
                     /note="glutamate rich 4"
                     /db_xref="GeneID:100170765"
                     /db_xref="HGNC:HGNC:34497"
     exon            1..188
                     /gene="ERICH4"
                     /gene_synonym="C19orf69"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..407
                     /gene="ERICH4"
                     /gene_synonym="C19orf69"
                     /codon_start=1
                     /product="glutamate-rich protein 4"
                     /protein_id="NP_001123986.1"
                     /db_xref="CCDS:CCDS46085.1"
                     /db_xref="GeneID:100170765"
                     /db_xref="HGNC:HGNC:34497"
                     /translation="MELWRQLNQAGLVPPGLGPPPQALREVSPVEIPGQTLRTAGADT
                     GGACDSLLWIREELGNLRRVDVQLLGQLCSLGLEMGALREELVTILEEEEESSKEEEE
                     DQEPQRKQEEEHLEACPAPHPPDFEMMI"
     exon            189..948
                     /gene="ERICH4"
                     /gene_synonym="C19orf69"
                     /inference="alignment:Splign:2.1.0"
     regulatory      834..839
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ERICH4"
                     /gene_synonym="C19orf69"
                     /note="hexamer: ATTAAA"
     polyA_site      860
                     /gene="ERICH4"
                     /gene_synonym="C19orf69"
                     /note="major polyA site"
     regulatory      927..932
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ERICH4"
                     /gene_synonym="C19orf69"
                     /note="hexamer: AGTAAA"
     polyA_site      948
                     /gene="ERICH4"
                     /gene_synonym="C19orf69"
ORIGIN      
        1 atagctcaga gacgatggaa ctgtggaggc agctgaatca ggctggactg gtgcctccgg
       61 ggctgggccc acccccccag gccctgaggg aggtctcccc agtggaaatc cctggtcaga
      121 ccctcaggac tgcaggggca gacactggag gtgcctgcga tagtctgctg tggatcaggg
      181 aggagctggg gaacctgcgc cgagtggatg tccagctgct gggacagctg tgcagcctgg
      241 ggctggagat gggggcgctg cgggaggaac tggtcaccat attggaggag gaggaggaga
      301 gcagcaagga agaggaggag gatcaagagc cccagaggaa gcaggaggag gaacacctgg
      361 aggcctgccc agccccacat ccacctgact ttgagatgat gatctgaggc tctgccagtg
      421 gatttagatt gacatacaaa tgagatgcaa atgtatgtaa aggagaaggg agatttgcag
      481 gtcaaagcag atgtggaatc aagtataccc ctttagtaag tgctttctct gaaggtgcct
      541 gcaatgatat ttaggcattg gcctgtgagc tatgggtgtg tttgcagatg acatgaggat
      601 gtgtttggag gtgatgtggg aggttgtaga gaagttgcag gtgctttcgc agatgagcct
      661 caggtgtgct gctgagatgg ggatctctgc aaatatgctg gtgatgcata cagatgcgat
      721 ttcagatcaa cgctgtccag tatggtagcc accggacaca catggttatt tagtgcttga
      781 aacatgggga ctgcaaattg agatgtgctg tgagtgtaaa atacacacca aatattaaag
      841 gcttagtatg atgaaaagaa cataagacat ctcaataatt tttagattac ttattgaaat
      901 aataatattt tgagcatatc agtattagta aaaatattac taaaatta
//
