LOCUS       XM_047449243            4738 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens epidermal growth factor receptor pathway
            substrate 15 (EPS15), transcript variant X4, mRNA.
ACCESSION   XM_047449243
VERSION     XM_047449243.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4738
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..4738
                     /gene="EPS15"
                     /gene_synonym="AF-1P; AF1P; MLLT5"
                     /note="epidermal growth factor receptor pathway substrate
                     15; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 4 mRNAs, 47 ESTs, 2863 long SRA reads, 1
                     Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 63 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:2060"
                     /db_xref="HGNC:HGNC:3419"
                     /db_xref="MIM:600051"
     CDS             64..2301
                     /gene="EPS15"
                     /gene_synonym="AF-1P; AF1P; MLLT5"
                     /codon_start=1
                     /product="epidermal growth factor receptor substrate 15
                     isoform X4"
                     /protein_id="XP_047305199.1"
                     /db_xref="GeneID:2060"
                     /db_xref="HGNC:HGNC:3419"
                     /db_xref="MIM:600051"
                     /translation="MFLVYCALEKEPVPMSLPPALVPPSKRKTVSISGSVRLIPSSAS
                     AKESYHSLPSVGILPTKAPLRQWVVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFL
                     KTGLPSTLLAHIWSLCDTKDCGKLSKDQFALAFHLISQKLIKGIDPPHVLTPEMIPPS
                     DRASLQKNIIGSSPVADFSAIKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSE
                     VQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLIS
                     SLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDS
                     QQEISSMQMKLMEMKDLENHNSQLNWCSSPHSILVNGATDYCSLSTSSSETANLNEHV
                     EGQSNLESEPIHQESPARSSPELLPSGVTDENEVTTAVTEKVCSELDNNRHSKEEDPF
                     NVDSSSLTGPVADTNLDFFQSDPFVGSDPFKDDPFGKIDPFGGDPFKGSDPFASDCFF
                     RQSTDPFATSSTDPFSAANNSSITSVETLKHNDPFAPGGTVVAASDSATDPFASVFGN
                     ESFGGGFADFSTLSKVNNEDPFRSATSSSVSNVVITKNVFEETSVKSEDEPPALPPKI
                     GTPTRPCPLPPGKRSINKLDSPDPFKLNDPFQPFPGNDSPKEKDPEIFCDPFTSATTT
                     TNKEADPSNFANFSAYPSEEDMIEWAKRESEREEEQRLARLNQQEQEDLELAIALSKS
                     EISEA"
ORIGIN      
        1 ttaccacatt ttaaaaatgc agaaagagaa acttaaagtg acttgaattc ttgttcacag
       61 gccatgtttt tggtatactg tgcactggag aaagaacctg tgccaatgtc cttgcctcca
      121 gccttggtgc caccatctaa gagaaaaacg gtcagtatat caggctctgt gcggttgatc
      181 ccctcttcag catcagccaa ggaatcttac cactccttac catctgtagg cattttacct
      241 accaaagcac cattaagaca gtgggttgta tcccctgcag aaaaagctaa atatgatgaa
      301 atcttcctga aaactgataa agatatggac ggatttgtgt ctggattgga ggtccgtgaa
      361 atattcttga aaacaggttt accttctacc ttactagccc atatatggtc attatgcgac
      421 acaaaggact gtgggaagct ttcaaaggat cagtttgcct tggcttttca cttaatcagt
      481 cagaagttaa tcaagggcat tgatcctcct cacgttctta ctcctgaaat gattccacca
      541 tcagacaggg ccagtttaca aaagaacatc ataggatcaa gtcctgttgc agatttctct
      601 gctattaagg aactagatac tcttaacaat gaaatagttg acctacagag ggaaaagaat
      661 aatgtggaac aggaccttaa ggagaaggaa gatactatta aacagaggac aagtgaggtt
      721 caggatcttc aagatgaagt tcaaagggag aatactaatc tgcaaaaact acaggcccag
      781 aaacagcagg tacaggaact ccttgatgaa ctggatgagc agaaagccca gctggaggag
      841 caactcaagg aagtcagaaa gaaatgtgct gaggaggccc aactgatctc ttctctgaaa
      901 gctgaattaa ctagtcagga atcgcagatc tccacttacg aagaagaatt ggcaaaagct
      961 agagaagagc tgagccgtct acagcaagaa acagcagaat tggaggagag tgtagagtca
     1021 gggaaggctc agttggaacc tcttcagcag cacctacaag attcacaaca ggaaattagt
     1081 tcaatgcaaa tgaaactgat ggaaatgaaa gatttggaaa atcataatag tcagttaaat
     1141 tggtgcagta gcccacacag cattcttgta aacggagcta cagattattg cagcctcagc
     1201 accagcagca gtgaaacagc caaccttaat gaacatgttg aaggccagag caacctagag
     1261 tctgagccca tacaccagga atctccagca agaagtagtc ctgaactact gccttctggt
     1321 gtgactgatg aaaatgaggt gactacagct gttactgaaa aagtttgttc tgaactcgac
     1381 aataatagac attcaaaaga ggaagatcca tttaatgtag actcaagttc gctgacaggt
     1441 ccagttgcag atacaaactt ggattttttc cagtctgatc cttttgttgg cagtgatcct
     1501 ttcaaggatg atccttttgg aaaaatcgat ccatttggtg gtgatccttt caaaggttca
     1561 gatccatttg catcagactg tttcttcagg caatctactg atccttttgc cacttcaagc
     1621 actgaccctt tcagtgcagc caacaatagc agtattacat cggtagaaac gttgaagcac
     1681 aatgatcctt ttgctcctgg tggaacagtt gttgcagcaa gcgattcagc cacagacccc
     1741 tttgcttctg tttttgggaa tgaatcattt ggaggtggat ttgctgactt cagcacattg
     1801 tcaaaggtca acaatgaaga tccttttcgt tcagccacat cgagctctgt cagcaacgta
     1861 gtgattacaa aaaatgtatt tgaggaaaca tcggtcaaaa gtgaagatga acccccagca
     1921 ctgccaccaa agatcggaac tccaacaaga ccctgccctc taccacctgg gaaaagatcc
     1981 atcaacaaat tggattctcc tgatcccttt aaactgaatg atccatttca gcctttccca
     2041 ggcaacgata gccccaaaga aaaagatcct gaaatatttt gtgatccatt cacttctgct
     2101 actaccacta ccaataaaga ggctgatcca agcaattttg ccaacttcag tgcttatccc
     2161 tctgaagaag atatgatcga atgggccaag agggaaagtg agagagagga agagcagagg
     2221 cttgcccgac taaatcagca ggaacaagaa gacttagaac tggctattgc actcagcaaa
     2281 tctgagatat cagaagcatg aagaattctc ttgttctttg gcaacaatat agtattcttc
     2341 ttcctgaata ctgaaactat ttacaatgtg tatcaaaact acctgtgagc atgggaatac
     2401 aaaaggtttg agattcctgt aaatgtgaca aaattttagg attttttttt tttcttcatt
     2461 acagattcgt cttttttttt ttttcttata aaagccgtaa cccagtcaga caaattcacc
     2521 ttcacttagg cccctgttct ggtatacatt tactgtgagc ttttgcctgc ctgtgctatt
     2581 ttacttgtaa agctagagca cccaagcttc tgccttctgg aatatagaga aatagtttca
     2641 ccctgcacta ccctgttctg tagttattct gatgatagcc agtgaggttc ttaaagtttg
     2701 cagtattctc ccctgattgg aatggttgag tgagggtaag ggaaagaata tcttatttct
     2761 tttatgattg gtgcaaattg gctaaagtgc atttttaaat ttcctctact taatttgttt
     2821 ttcagagata aggaaaaata ttttgcacag atttactcca ctatggaaaa gggatgctgt
     2881 aggttgaacc attatagcct cagattcgat cttttcctaa ctaaaaatat taaagcctca
     2941 tgtgtgaaat aaatttttaa aaagatttat ctggatttag agaattttag atcaacagat
     3001 acctctcagt gtgtttgcta attaataaaa atcagtttct tacaaataaa gtttgtaaga
     3061 aaatgttcat tttaagtgat agatagtgga gaaaatttat cacctaaaat atacccatca
     3121 gtataaggca agcaaaagtc ttaacatggc agccattctg cctttgccgt ggccctgtcc
     3181 tgtttagttc ttagtgggtt aatttttgta cttttgcaga agaaacttca gcaagctaga
     3241 actggaaggt actttaattt ttcatatata tttgtttttt tttttttaat gaaggctcat
     3301 ttacttgaaa tgtaaaaact ttcactgaat acaaatagaa aaagtgatgt gttttatatc
     3361 atattgcttt ttgtccatct ttgtggttta gtttatttac tcacttcatg tttttcacct
     3421 ataaaattgt caagctagca aaaaaactct tgttttttta attgggagag aagagacctg
     3481 ccagattatc agacctcttc atgttaaaag accatctcct gtaaaactga cctagtggac
     3541 aagctgaatt tgaaatagac tgtgaagtaa gctgtaactt gtcattttaa ttttgtttaa
     3601 cacggttact gacttagatg atgtattaaa taccaagata aagaaaaatg cacctaaaat
     3661 ctaattagaa ttctctgggt caacaagtca aggtggtatt gatctgtgtt aatctgagta
     3721 acttattgcc tagcctataa ataaattcca aaatatccaa ttcatttctt cttgaaatgg
     3781 tgcttgtttt gttttctttc cattacacaa ttagactcct acagtttaaa acaaacttta
     3841 aaccactatc ttgcactgct aacttttttc tacctttgta aatagaaaca tttctgcata
     3901 aaagtcatac atatgaagca agggctgaat cataatcaca aggcttaatt ttgataaacg
     3961 aatccagtga cctaaggatt ttctgcaaaa tttgactggg agttgtgata ggtggtattt
     4021 ttgtttattt tcttcctctt actccttagg ataaaggtaa gttgacttga acaactttct
     4081 tttgcactgg gaaaataagc aaatgtttaa atgcttcaaa aaaattttca attaaactca
     4141 aatattaaat atctataact tataaacacc aactttcaat gtaataaatg tatcctaatc
     4201 ttatgtatgt ttaactggat tacatagatt tttatctttt gttaaaatgt gtataccccg
     4261 tggaccaaca taatattaaa gtatgtatat attatataaa tatatatgta tatgtgctcg
     4321 cttgtgtagg atgaatgtct tagagtcgtt tgtggtattt tatgttgttg actctggctc
     4381 cagggcctgt gcttgaaaag gacagataag tattgcccag agctaagtgg cactacttac
     4441 aaagttttaa atgtcttcta catactgatt catgtttatt tgagctctct ttatagaatt
     4501 ttctcttaaa gtttcaaacc tctaagttgt agcctgtaat tatgagaaca gtaaacttta
     4561 agtaataata aagaatccca tccatatatc caatttgcaa ttgagttttg catggttctc
     4621 tgattatgtc catgctgtgt ccaaggagga gtaggtacat acaatcagca cagattaata
     4681 tatgtaaagg gtttgggaca gcacctggta tagaataaat aataaatgta aactatta
//
