LOCUS       XM_017000617            4959 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens epidermal growth factor receptor pathway
            substrate 15 (EPS15), transcript variant X2, mRNA.
ACCESSION   XM_017000617
VERSION     XM_017000617.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017000617.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4959
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..4959
                     /gene="EPS15"
                     /gene_synonym="AF-1P; AF1P; MLLT5"
                     /note="epidermal growth factor receptor pathway substrate
                     15; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 51 ESTs, 1969 long SRA reads, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 94 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:2060"
                     /db_xref="HGNC:HGNC:3419"
                     /db_xref="MIM:600051"
     CDS             36..2522
                     /gene="EPS15"
                     /gene_synonym="AF-1P; AF1P; MLLT5"
                     /codon_start=1
                     /product="epidermal growth factor receptor substrate 15
                     isoform X2"
                     /protein_id="XP_016856106.1"
                     /db_xref="GeneID:2060"
                     /db_xref="HGNC:HGNC:3419"
                     /db_xref="MIM:600051"
                     /translation="MAAAAQLSLTQLSSGNPVYEKYYRQVDTGNTGRVLASDAAAFLK
                     KSGLPDLILGKIWDLADTDGKGILNKQEFFVALRLVACAQNGLEVSLSSLNLAVPPPR
                     FHDTSSPLLISGTSAAELPWAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKL
                     PVDILGRVWELSDIDHDGMLDRDEFAVAMFLVYCALEKEPVPMSLPPALVPPSKRKTW
                     VVSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGK
                     LSKDQFALAFHLISQKLIKGIDPPHVLTPEMIPPSDRASLQKNIIGSSPVADFSAIKE
                     LDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQ
                     QVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKA
                     REELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSARSSPELLPSGVTDENE
                     VTTAVTEKVCSELDNNRHSKEEDPFNVDSSSLTGPVADTNLDFFQSDPFVGSDPFKDD
                     PFGKIDPFGGDPFKGSDPFASDCFFRQSTDPFATSSTDPFSAANNSSITSVETLKHND
                     PFAPGGTVVAASDSATDPFASVFGNESFGGGFADFSTLSKVNNEDPFRSATSSSVSNV
                     VITKNVFEETSVKSEDEPPALPPKIGTPTRPCPLPPGKRSINKLDSPDPFKLNDPFQP
                     FPGNDSPKEKDPEIFCDPFTSATTTTNKEADPSNFANFSAYPSEEDMIEWAKRESERE
                     EEQRLARLNQQEQEDLELAIALSKSEISEA"
ORIGIN      
        1 gtcttccttc ccctcccttg catgatggaa acaccatggc tgcggcggcc cagctctctc
       61 tgacacagtt atcaagtggg aatcctgtat atgaaaaata ctatagacag gttgatacag
      121 gcaatactgg aagggtgttg gcttctgatg ctgctgcttt cctgaaaaaa tcagggcttc
      181 cagacttgat acttggaaag atttgggatt tagccgacac agatggcaaa ggtatcctga
      241 acaaacaaga attctttgtt gctttgcgtc ttgtggcatg tgcccagaat ggattggaag
      301 tttcactaag tagtttgaac ctggctgttc ctccaccaag atttcatgat accagtagtc
      361 ctttgctaat cagtggaacc tctgcagctg agctcccatg ggctgtaaaa cctgaagata
      421 aggccaaata tgatgcaata tttgatagtt taagcccagt gaatggattt ctgtctggtg
      481 ataaagtgaa accagtgttg ctcaactcta agttacctgt ggatatcctt ggaagagttt
      541 gggagttgag tgatattgac catgatggaa tgcttgacag agatgagttt gcagttgcca
      601 tgtttttggt atactgtgca ctggagaaag aacctgtgcc aatgtccttg cctccagcct
      661 tggtgccacc atctaagaga aaaacgtggg ttgtatcccc tgcagaaaaa gctaaatatg
      721 atgaaatctt cctgaaaact gataaagata tggacggatt tgtgtctgga ttggaggtcc
      781 gtgaaatatt cttgaaaaca ggtttacctt ctaccttact agcccatata tggtcattat
      841 gcgacacaaa ggactgtggg aagctttcaa aggatcagtt tgccttggct tttcacttaa
      901 tcagtcagaa gttaatcaag ggcattgatc ctcctcacgt tcttactcct gaaatgattc
      961 caccatcaga cagggccagt ttacaaaaga acatcatagg atcaagtcct gttgcagatt
     1021 tctctgctat taaggaacta gatactctta acaatgaaat agttgaccta cagagggaaa
     1081 agaataatgt ggaacaggac cttaaggaga aggaagatac tattaaacag aggacaagtg
     1141 aggttcagga tcttcaagat gaagttcaaa gggagaatac taatctgcaa aaactacagg
     1201 cccagaaaca gcaggtacag gaactccttg atgaactgga tgagcagaaa gcccagctgg
     1261 aggagcaact caaggaagtc agaaagaaat gtgctgagga ggcccaactg atctcttctc
     1321 tgaaagctga attaactagt caggaatcgc agatctccac ttacgaagaa gaattggcaa
     1381 aagctagaga agagctgagc cgtctacagc aagaaacagc agaattggag gagagtgtag
     1441 agtcagggaa ggctcagttg gaacctcttc agcagcacct acaagattca caacaggaaa
     1501 ttagttcagc aagaagtagt cctgaactac tgccttctgg tgtgactgat gaaaatgagg
     1561 tgactacagc tgttactgaa aaagtttgtt ctgaactcga caataataga cattcaaaag
     1621 aggaagatcc atttaatgta gactcaagtt cgctgacagg tccagttgca gatacaaact
     1681 tggatttttt ccagtctgat ccttttgttg gcagtgatcc tttcaaggat gatccttttg
     1741 gaaaaatcga tccatttggt ggtgatcctt tcaaaggttc agatccattt gcatcagact
     1801 gtttcttcag gcaatctact gatccttttg ccacttcaag cactgaccct ttcagtgcag
     1861 ccaacaatag cagtattaca tcggtagaaa cgttgaagca caatgatcct tttgctcctg
     1921 gtggaacagt tgttgcagca agcgattcag ccacagaccc ctttgcttct gtttttggga
     1981 atgaatcatt tggaggtgga tttgctgact tcagcacatt gtcaaaggtc aacaatgaag
     2041 atccttttcg ttcagccaca tcgagctctg tcagcaacgt agtgattaca aaaaatgtat
     2101 ttgaggaaac atcggtcaaa agtgaagatg aacccccagc actgccacca aagatcggaa
     2161 ctccaacaag accctgccct ctaccacctg ggaaaagatc catcaacaaa ttggattctc
     2221 ctgatccctt taaactgaat gatccatttc agcctttccc aggcaacgat agccccaaag
     2281 aaaaagatcc tgaaatattt tgtgatccat tcacttctgc tactaccact accaataaag
     2341 aggctgatcc aagcaatttt gccaacttca gtgcttatcc ctctgaagaa gatatgatcg
     2401 aatgggccaa gagggaaagt gagagagagg aagagcagag gcttgcccga ctaaatcagc
     2461 aggaacaaga agacttagaa ctggctattg cactcagcaa atctgagata tcagaagcat
     2521 gaagaattct cttgttcttt ggcaacaata tagtattctt cttcctgaat actgaaacta
     2581 tttacaatgt gtatcaaaac tacctgtgag catgggaata caaaaggttt gagattcctg
     2641 taaatgtgac aaaattttag gatttttttt ttttcttcat tacagattcg tctttttttt
     2701 tttttcttat aaaagccgta acccagtcag acaaattcac cttcacttag gcccctgttc
     2761 tggtatacat ttactgtgag cttttgcctg cctgtgctat tttacttgta aagctagagc
     2821 acccaagctt ctgccttctg gaatatagag aaatagtttc accctgcact accctgttct
     2881 gtagttattc tgatgatagc cagtgaggtt cttaaagttt gcagtattct cccctgattg
     2941 gaatggttga gtgagggtaa gggaaagaat atcttatttc ttttatgatt ggtgcaaatt
     3001 ggctaaagtg catttttaaa tttcctctac ttaatttgtt tttcagagat aaggaaaaat
     3061 attttgcaca gatttactcc actatggaaa agggatgctg taggttgaac cattatagcc
     3121 tcagattcga tcttttccta actaaaaata ttaaagcctc atgtgtgaaa taaattttta
     3181 aaaagattta tctggattta gagaatttta gatcaacaga tacctctcag tgtgtttgct
     3241 aattaataaa aatcagtttc ttacaaataa agtttgtaag aaaatgttca ttttaagtga
     3301 tagatagtgg agaaaattta tcacctaaaa tatacccatc agtataaggc aagcaaaagt
     3361 cttaacatgg cagccattct gcctttgccg tggccctgtc ctgtttagtt cttagtgggt
     3421 taatttttgt acttttgcag aagaaacttc agcaagctag aactggaagg tactttaatt
     3481 tttcatatat atttgttttt ttttttttaa tgaaggctca tttacttgaa atgtaaaaac
     3541 tttcactgaa tacaaataga aaaagtgatg tgttttatat catattgctt tttgtccatc
     3601 tttgtggttt agtttattta ctcacttcat gtttttcacc tataaaattg tcaagctagc
     3661 aaaaaaactc ttgttttttt aattgggaga gaagagacct gccagattat cagacctctt
     3721 catgttaaaa gaccatctcc tgtaaaactg acctagtgga caagctgaat ttgaaataga
     3781 ctgtgaagta agctgtaact tgtcatttta attttgttta acacggttac tgacttagat
     3841 gatgtattaa ataccaagat aaagaaaaat gcacctaaaa tctaattaga attctctggg
     3901 tcaacaagtc aaggtggtat tgatctgtgt taatctgagt aacttattgc ctagcctata
     3961 aataaattcc aaaatatcca attcatttct tcttgaaatg gtgcttgttt tgttttcttt
     4021 ccattacaca attagactcc tacagtttaa aacaaacttt aaaccactat cttgcactgc
     4081 taactttttt ctacctttgt aaatagaaac atttctgcat aaaagtcata catatgaagc
     4141 aagggctgaa tcataatcac aaggcttaat tttgataaac gaatccagtg acctaaggat
     4201 tttctgcaaa atttgactgg gagttgtgat aggtggtatt tttgtttatt ttcttcctct
     4261 tactccttag gataaaggta agttgacttg aacaactttc ttttgcactg ggaaaataag
     4321 caaatgttta aatgcttcaa aaaaattttc aattaaactc aaatattaaa tatctataac
     4381 ttataaacac caactttcaa tgtaataaat gtatcctaat cttatgtatg tttaactgga
     4441 ttacatagat ttttatcttt tgttaaaatg tgtatacccc gtggaccaac ataatattaa
     4501 agtatgtata tattatataa atatatatgt atatgtgctc gcttgtgtag gatgaatgtc
     4561 ttagagtcgt ttgtggtatt ttatgttgtt gactctggct ccagggcctg tgcttgaaaa
     4621 ggacagataa gtattgccca gagctaagtg gcactactta caaagtttta aatgtcttct
     4681 acatactgat tcatgtttat ttgagctctc tttatagaat tttctcttaa agtttcaaac
     4741 ctctaagttg tagcctgtaa ttatgagaac agtaaacttt aagtaataat aaagaatccc
     4801 atccatatat ccaatttgca attgagtttt gcatggttct ctgattatgt ccatgctgtg
     4861 tccaaggagg agtaggtaca tacaatcagc acagattaat atatgtaaag ggtttgggac
     4921 agcacctggt atagaataaa taataaatgt aaactatta
//
