LOCUS       XM_047422293           16184 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens epiplakin 1 (EPPK1), transcript variant X4,
            mRNA.
ACCESSION   XM_047422293
VERSION     XM_047422293.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000008.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16184
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
     gene            1..16184
                     /gene="EPPK1"
                     /gene_synonym="EPIPL; EPIPL1"
                     /note="epiplakin 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 14 ESTs, 183 long
                     SRA reads, 11 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 5 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:83481"
                     /db_xref="HGNC:HGNC:15577"
                     /db_xref="MIM:607553"
     CDS             255..15521
                     /gene="EPPK1"
                     /gene_synonym="EPIPL; EPIPL1"
                     /codon_start=1
                     /product="epiplakin isoform X3"
                     /protein_id="XP_047278249.1"
                     /db_xref="GeneID:83481"
                     /db_xref="HGNC:HGNC:15577"
                     /db_xref="MIM:607553"
                     /translation="MSGHTLPPLPVPGTNSTEQASVPRAMAATLGAGTPPRPQARSIA
                     GVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQG
                     LVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGL
                     VDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLDPNTLERLTYHQLLERC
                     VRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAE
                     VRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITG
                     QRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLAL
                     RLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLSQAGSFSDGTHGGLRYEQ
                     LLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPV
                     SLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAKLSATLEQAAATARVTFSGLRDT
                     VTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASVQRYLQGTGCIAGLLLPGSQERL
                     SIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLL
                     SAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPV
                     DVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPL
                     SSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQ
                     REVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPE
                     ALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGT
                     IMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGL
                     IPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSETFPTPD
                     GQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLWD
                     LLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVP
                     AVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASI
                     AQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQA
                     ERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAA
                     ACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPS
                     DTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGR
                     AAALRQVVSAVTTLVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTT
                     TVKEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAA
                     TGFIIDPVENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQ
                     KDLIVREHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTK
                     GFFDPNTHENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKM
                     RVGRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQN
                     QGIKVAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSGCIA
                     GVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVG
                     LVNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGV
                     IDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRP
                     QEDTGWLLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVT
                     EEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSA
                     IITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQA
                     MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERA
                     VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR
                     RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGS
                     AVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTL
                     TVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWD
                     VLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPR
                     EPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAAAARRQEQTLRDATMEVQRGQFQG
                     RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRG
                     LRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAK
                     DQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVV
                     GGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVID
                     PVHSHRVPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDP
                     DTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSED
                     RRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEV
                     KVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAP
                     GARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAARRQEQTLRDATM
                     EVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEE
                     RLSKVSFRGLRCQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSC
                     IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSV
                     EEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA
                     QIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQ
                     LLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWEL
                     LFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPRE
                     ALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTA
                     IIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAA
                     RRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLV
                     AVLTRVIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEM
                     DSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGF
                     VIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDL
                     IVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFF
                     DPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSG
                     ALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAE
                     AEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGT
                     LDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEG
                     ETQEAAAATAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQ
                     HAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLA
                     QGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGHQEKMSIYQAMWKGVLRPGTA
                     LVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQ
                     QISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRV
                     LAHPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRC
                     ALRDARVMPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTS
                     LLAQAQAQARAEAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSG
                     AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGD
                     GDSGRSQREGQGEGETQEAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYL
                     SEAHRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSG
                     ILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQA
                     MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERA
                     VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR
                     RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSLQ"
ORIGIN      
        1 ggggtctcgc aggcccagcg gttttccctg cagcgaggac cgcccggggc acgctctgca
       61 gggtggggaa cgcccaggcc aggaggcagc taggccgaca aattgagagg ggtgactcct
      121 ggcaacattg ccgggaggga ggcgtcacgg atccggggaa gctgcctgct gttgggtgag
      181 cggtcccagg ggtggccact ccgggtcagg acagaggtgg acctcagcag gctctgcata
      241 accagccgtg tgtgatgagt ggccacacct tgcctcctct tcccgtccca ggcaccaaca
      301 gcacagagca ggccagtgta cccagagcca tggcagccac gctgggagcc ggcacgcccc
      361 ccaggcccca ggccaggagc atagctgggg tgtatgtgga ggcctcgggc caggcccaga
      421 gtgtctacgc cgccatggag cagggcctcc tgcctgctgg gctcgggcag gctctgctag
      481 aggcccaggc agccactggg ggcctggtgg acctcgcccg gggccagctg ctccctgtgt
      541 ccaaggccct gcagcagggt ctggtggggc tggagctgaa ggagaagctg ctggccgctg
      601 agcgtgccac tacgggctat cctgacccct acggcggtga gaagctggcc ctctttcagg
      661 ccatcgggaa ggaggttgtg gacagggccc tggggcagag ctggctggag gtccaactgg
      721 ccactggggg cctggtggac cccgcccagg gagtgctcgt ggcccctgag ccagcctgcc
      781 accagggcct cctggaccgg gagacatggc acaagctgtc agagcttgag cctggcacag
      841 gtgacctgcg cttcctcgac cccaacacgc tggagcggct gacataccac cagctgctgg
      901 aaaggtgtgt gcgtgccccc ggctcggggc tagccttgct gcccctcaag atcaccttcc
      961 gctccatggg cggggcggtg agtgcagctg agctgctgga ggtgggcatc ctggacgagc
     1021 aggctgtgca gggtctgcgg gagggcaggc tggccgcagt ggacgtgagt gcacgtgccg
     1081 aggtgcggcg ctacctggag ggtaccggca gcgtggccgg ggttgtcctg ctgcccgaag
     1141 gccacaagaa gagctttttc caggctgcca ccgagcacct gctcccaatg ggcaccgcgc
     1201 tgccactcct agaggcccag gctgccaccc acaccctggt ggaccccatc acaggccagc
     1261 ggctgtgggt agacgaggca gtcagggcgg gcctggtcag cccagagctc catgagcagc
     1321 tcctggtggc cgagcaggcc gtgacagggc accacgaccc cttcagtggc tcccaaatcc
     1381 cccttttcca ggccatgaag aaggggctag tggacaggcc actggcactg cggctcttgg
     1441 atgcccagct ggccacaggc gggctggtct gtccagcacg caggctccgg ctgcccctgg
     1501 aggccgccct gcgctgcggc tgcctggatg aagacactca gcggcagctc tcgcaggctg
     1561 gcagcttctc agacggcacg cacggcggcc tgcgctatga acagctgctg gccctctgtg
     1621 tcaccgaccc agagaccggg cttgccttcc tgccactctc agggggaccc cggggagggg
     1681 agccccaggg acccccattc atcaagtaca gcactcggca ggccctgagc acggccacag
     1741 ccaccgtctc tgtggggaag ttccggggcc ggcccgtgtc cctctgggag ctgctcttct
     1801 ctgaggccat ctcctcagag cagagggcga tgctggccca gcagtaccag gaagggaccc
     1861 tctccgtgga gaagctggcc gctaagctga gcgccaccct cgagcaggct gcagccactg
     1921 ccagggtcac cttttctggg ctgagggaca ccgtgacacc aggagagctg ctgaaagccg
     1981 agatcatcga ccaggacctg tacgagcggc tggagcatgg acaggccaca gccaaggatg
     2041 tgggcagcct ggcctcggtg cagaggtacc tgcagggtac gggctgcatt gctggcctgc
     2101 tgctccctgg ctcccaggaa cgcctgagca tctatgaggc ccgatgcaag gggctcctcc
     2161 ggcccggcac tgccctcatc cttctggagg cacaagctgc cacaggcttc atcatcgacc
     2221 caaaagcaaa caaggggcac tccgttgagg aggcactgag ggctgctgtc attgggcctg
     2281 atgtgttcgc gaagctgctg tcggctgagc gcgctgtcac tggctacact gacccctaca
     2341 ccgggcagca gatctccctc ttccaggcca tgcagaaggg cctcatcgtc cgggagcacg
     2401 gcatccgcct gctggaggcc cagatcgcca cgggcggcgt catcgacccc gtgcacagcc
     2461 accgcgtgcc cgtggacgtg gcctaccggc gcggctactt cgatcagatg ctgaacttga
     2521 tcctgttgga cccttctgac gacaccaagg gcttcttcga ccccaacacg cacgagaacc
     2581 tcacgtacct gcagcttctg gagcgctgtg tgcgtgaccc cgagacgggc ctgtacctcc
     2641 tgccactcag cagcacgcag tccccgctgg tggacagtgc cacccagcag gccttccaga
     2701 acctgctgct ctccgtgaag tatggacggt ttcaggggca gagggtctcc gcgtgggagc
     2761 tgatcaactc tgagtacttc agcgagggcc gcaggaggca gctgctgcgt cgctaccggc
     2821 agcgcgaggt cacgctgggg caggtggcaa agctgctgga ggcggagacg cagagacagg
     2881 cggacatcat gctgcccgca ctgcggagcc gggtcaccgt ccaccagctc ctggaggccg
     2941 gtatcattga ccagcagctg ttggaccaag tgctggccgg gacaatcagc ccggaggccc
     3001 tcctactcat ggacggcgtc cgcaggtacc tgtgcggcct gggagctgtg ggcggtgtgc
     3061 ggctgctgcc ctctggccag cggctcagcc tctaccaggc catgaggcag aagctgctgg
     3121 ggcccagggt ggccctggcc ctgctggagg cccaggcggc caccggaacc atcatggacc
     3181 ctcacagccc agagagcctc tcggtggatg aggccgtgcg caggggtgtg gtggggccgg
     3241 agctgtatgg caggctgaag cgggctgagg gtgccattgc tggcttcaga gaccccttct
     3301 ctgggaagca ggtgtctgtg ttccaggcca tgaagaaagg tctcatccct tgggagcaag
     3361 ctgcccgcct cctggaggct caagtggcca caggagggat cattgacccc accagccacc
     3421 accacctccc catgccagtg gccattcagc gtggctatgt tgaccaggag atggagacag
     3481 ccttgtccag ctcctccgaa accttcccca caccggacgg ccaggggcgc acgagctatg
     3541 cccagctcct ggaggagtgc cccagggatg agacttctgg ccttcacctc ctgcccctgc
     3601 cagaaagtgc tcctgccctc cccaccgagg agcaggtcca gaggagcctg caggccgtgc
     3661 cgggggccaa ggatggcaca tccctctggg acctgctcag ctcctgccac ttcaccgagg
     3721 agcaacggag gggcctgctg gaggacgtgc aggaggggag gaccactgtg ccacagctgc
     3781 tagcctctgt gcagaggtgg gtacaggaga ccaagctcct ggcccaggcc cgcgtcatgg
     3841 tgcccggccc acggggtgag gtacccgctg tctggctgct ggatgctggc atcatcaccc
     3901 aggagaccct tgaggccctg gctcagggca cgcagtcgcc cgcccaggtc gccgagcagc
     3961 cggcggtgaa ggcctgcctg tggggcacag gctgcgtggc cggtgtgctg ctacagccct
     4021 ctggggccaa ggccagcatc gcccaggccg tgagggatgg cctcctgccc acaggcctgg
     4081 gccagaggct gctggaagcc caggtggcat ctggcttcct tgttgacccc ctgaacaacc
     4141 agagactgtc agtggaggac gcggttaagg tcggcctggt gggcagggag ctgagtgagc
     4201 agctcgggca ggccgagagg gcggcggccg ggtacccaga tccctactct agggcctccc
     4261 tctctctgtg gcaggccatg gagaaggggc tcgtgccaca gaacgagggc ttgcccctcc
     4321 tgcaggtgca gctggccaca gggggtgtgg tggaccctgt ccacggggtg cacctgcccc
     4381 aggcggcagc ctgcagactc ggccttctgg acacacagac gagccaggtg ctgactgcag
     4441 ttgacaagga caacaagttc ttctttgacc ccagtgcgcg ggaccaggtg acctaccagc
     4501 agctcaggga gcgctgcgtg tgcgactccg agaccggatt gttgctgttg ccactgccct
     4561 cagacacagt gcttgaggtg gacgaccaca ccgcggtggc tctgagggcc atgaaggtgc
     4621 ccgtcagcac agggaggttt aaggggtgta gcgtgtcact ctgggacctg ctgctctccg
     4681 aatacgttgg cgctgacaag cggcgggagc tggtggcact ctgtcggtct gggagggctg
     4741 cggccctgcg gcaggtggtc agcgcagtca ccaccctggt cgaggctgca gagaggcagc
     4801 ccctgcaggc caccttcaga gggctccgga agcaggtgtc agccagggac ctgttcaggg
     4861 cgcagctgat cagcaggaag acgctggacg agctgagcca ggggacaacg actgtgaagg
     4921 aggtggcgga gatggacagc gtgaagcggt ccctggaggg aggcaacttc attgccgggg
     4981 tccttatcca gggcacccag gagaggatga gcatcccaga ggccctgagg aggcacatcc
     5041 tgcggcctgg cacagccctg gtgctgctgg aggcacaggc agctaccggc ttcatcatcg
     5101 accccgtgga gaaccggaag ctgaccgtgg aggaggcgtt caaagcagga atgttcggga
     5161 aagaaaccta cgtgaagctg ctgtcggccg agcgcgccgt caccggctac accgacccct
     5221 ataccgggca gcagatctcc ctcttccagg ccatgcagaa ggacctcatc gtccgggagc
     5281 acggcatccg cctgctggag gcccagatcg ccacgggcgg catcatcgac cccgtgcaca
     5341 gccaccgcgt gcccgtggac gtggcctacc gctgcggcta cttcgacgag gagatgaacc
     5401 gcatcctggc ggaccccagc gacgacacca agggcttctt cgaccccaac acgcacgaga
     5461 acctcacgta cctgcagctt ctggagcgct gtgtggagga ccccgagacg ggcctgtacc
     5521 tgctacaaat cataaagaaa ggagaaaact acgtgtacat caatgaggcc acgagacacg
     5581 tgttgcaatc cagaactgca aaaatgcgcg tggggaggtt tgctgaccag gtggtctctt
     5641 tctgggacct gctgtcctct ccatacttca cagaggacag gaagcgggag ctcatccagg
     5701 agtatggagc ccagagtggg ggcctggaga aattgctgga aatcatcacc acgacaattg
     5761 aagaaacaga gacgcaaaac caaggcatca aagtggcggc catcagaggg gaggtgacag
     5821 ctgcagacct gttcaactcc agggtcatcg atcagaagac cctgcacaca cttcgtgtgg
     5881 ggaggactgg gggacaggca ctcagcacgc tggagtgtgt gaagccctat ctggaaggca
     5941 gcggctgcat tgcgggggtc acggtgccct ccaccaggga ggtcatgagc ctccatgagg
     6001 ccagcaggaa ggagctcatc cctgcagcat ttgcgacttg gctgctggag gcgcaggccg
     6061 ccaccgggtt cctcctggac ccctgcaccc gccagaagct ctctgtggat gaggctgtgg
     6121 atgtgggcct ggtgaacgag gagctgcggg agaggctcct gaaggctgaa agagctgcca
     6181 cgggctacag ggatccggcc acaggagaca cgatcccgct gttccaggcc atgcagaagc
     6241 agctcatcga gaaggcggag gcactgaggc tgctggaggt gcaggtggcc acggggggtg
     6301 tcatcgaccc acagcaccac caccggctcc cactggaaac agcctacaga cggggctgtc
     6361 tgcacaagga catctatgcg ctcatttccg accagaagca catgaggaaa cggtttgtgg
     6421 acccgaacac gcaagagaag gtctcgtacc gagagctgca ggagaggtgc cgcccacaag
     6481 aggacacggg ctggctgctg ttcccagtga acaaggctgc acgggactcc gagcacatcg
     6541 atgacgagac gagaagggcc ctggaggcag agcaagtgga aatcacagtg ggaaggttca
     6601 gaggccagaa accaacactg tgggcactac tgaattccga atacgtgaca gaggagaaga
     6661 agctccagct ggtgaggatg tatagaacac acaccagacg ggcactgcag acggtagcgc
     6721 agctcatctt agagttgatc gagaagcagg aaaccagcaa caaacacctg tggttccaag
     6781 gaattagacg acagatcaca gcttctgaac tcctcagctc agccataatc acggaggaaa
     6841 tgctccagga cctggaaacg ggacggagca cgacgcaaga gctcatggag gacgaccgcg
     6901 tcaagcgcta cctggagggc accagctgca tcgcgggcgt cctggtgccc gccaaggacc
     6961 agcccggccg ccaggagaag atgagcatct accaggccat gtggaagggc gtgctgcggc
     7021 ccggcacggc cctggtgctg ctggaggcgc aggcggccac cggcttcgtc atcgaccccg
     7081 tgcgcaacct gaggctgtcg gtggaggagg ccgtggccgc gggcgtggtg ggcggcgaga
     7141 tccaggagaa gctgctgtcg gccgagcgcg ccgtcaccgg ctacaccgac ccctacaccg
     7201 ggcagcagat ctccctcttc caggccatgc agaaggacct catcgtccgg gagcacggca
     7261 tccgcctgct ggaggcccag atcgccacgg gcggcgtcat cgaccccgtg cacagccacc
     7321 gcgtgcccgt ggacgtggcc taccggcgcg gctacttcga cgaggagatg aaccgtgtcc
     7381 tggccgaccc cagcgacgac accaagggct tcttcgaccc caacacgcac gagaacctca
     7441 cgtacgtgca gctgctgcgc cgctgcgtgc ccgacccgga caccgggctc tacatgctgc
     7501 agctggcagg ccggggctcc gccgtgcacc agctgagcga ggagctgcgc tgtgccctgc
     7561 gcgacgcccg cgtgacgcca ggctcgggcg ccctccaggg ccagagcgtc tccgtctggg
     7621 agctcctctt ctaccgcgag gtgtccgagg accggcgcca ggacctgctg agcagatacc
     7681 gggcgggcac gctgaccgtg gaggagctgg gcgccaccct cacctcgctg ctggcccagg
     7741 cccaggccca ggcccgggcc gaggccgagg ccgggagccc gcgcccagac ccccgggagg
     7801 ccctgcgtgc ggccaccatg gaggtcaagg tgggccgcct ccgggggcgc gcggtgcccg
     7861 tgtgggacgt gctggcgtcc ggctacgtga gcagggccgc ccgggaggag ctgctggccg
     7921 agtttggctc ggggaccctg gacttgcccg cgctgacccg ccggctgacc gccatcatcg
     7981 aggaggccga ggaggccccc ggggcccggc cgcagctcca ggacgcctgg cgcggcccgc
     8041 gggagccagg gccagccggg cgaggggacg gcgactcggg gcgctcccag cgagagggcc
     8101 agggggaggg cgagacccag gaggccgccg ccgccgccgc cgccgccgcc gcccgccgcc
     8161 aggagcagac cctgcgtgat gccaccatgg aggtgcagcg cgggcagttc caggggcggc
     8221 cggtctccgt gtgggacgtc ctcttctcct cgtacctgag cgaggcccgc cgagacgagc
     8281 tcctggccca gcacgcggcc ggcgccctgg gcctgcccga cctcgtcgcc gtcctcaccc
     8341 gggtcatcga ggagaccgag gagcggctca gcaaggtgtc cttccgcggc ctgaggcgcc
     8401 aggtgtccgc ctccgagctg cacacgtccg ggatcctggg ccccgagacc ctgcgggacc
     8461 tggcccaggg cactaagacg ctgcaggagg tgacggagat ggactcggtc aagcgctacc
     8521 tggagggcac cagctgcatc gcgggcgtcc tggtgcccgc caaggaccag cccggccgcc
     8581 aggagaagat gagcatctac caggccatgt ggaagggcgt gctgcggccc ggcacggccc
     8641 tggtgctgct ggaggcgcag gcggccaccg gcttcgtcat cgaccccgtg cgcaacctga
     8701 ggctgtcggt ggaggaggcc gtggccgcgg gcgtggtggg cggcgagatc caggagaagc
     8761 tgctgtcggc cgagcgcgcc gtcaccggct acaccgaccc ctacaccggg cagcagatct
     8821 ccctcttcca ggccatgcag aaggacctca tcgtccggga gcacggcatc cgcctgctgg
     8881 aggcccagat cgccacgggc ggcgtcatcg accccgtgca cagccaccgc gtgcccgtgg
     8941 acgtggccta ccagcgcggc tacttcgacg aggagatgaa ccgtgtcctg gccgacccca
     9001 gcgacgacac caagggcttc ttcgacccca acacgcacga gaacctcacg tacgtgcagc
     9061 tgctgcgccg ctgcgtgccc gacccggaca ccgggctcta catgctgcag ctggcaggcc
     9121 ggggctccgc cgtgcaccag ctgagcgagg agctgcgctg tgccctgcgc gacgcccgcg
     9181 tgacgccagg ctcgggcgcc ctccagggcc agagcgtctc cgtctgggag ctcctcttct
     9241 accgcgaggt gtccgaggac cggcgccagg acctgctgag cagataccgg gcgggcacgc
     9301 tgaccgtgga agagctgggc gccaccctca cctcgctgct ggcccaggcc caggcccagg
     9361 cccgggccga ggccgaggcc gggagcccgc gcccagaccc ccgggaggcc ctgcgtgcgg
     9421 ccaccatgga ggtcaaggtg ggccgcctcc gggggcgcgc ggtgcccgtg tgggacgtgc
     9481 tggcgtccgg ctacgtgagc agggccgccc gggaggagct gctggccgag tttggctcgg
     9541 ggaccctgga cttgcccgcg ctgacccgcc ggctgaccgc catcatcgag gaggccgagg
     9601 aggcccccgg ggcccggccg cagctccagg acgcctggcg cggcccgcgg gagccagggc
     9661 cagccgggcg aggggacggc gactcggggc gctcccagcg agagggccag ggggagggcg
     9721 agacccagga ggccgccgcc gccgcccgcc gccaggagca gaccctgcgt gatgccacca
     9781 tggaggtgca gcgcgggcag ttccaggggc ggccggtctc cgtgtgggac gtcctcttct
     9841 cctcgtacct gagcgaggcc cgccgagacg agctcctggc ccagcacgcg gccggcgccc
     9901 tgggcctgcc cgacctcgtc gccgtcctca cccgggtcat cgaggagacg gaggagcggc
     9961 tcagcaaggt gtccttccgc ggcctgaggt gccaggtgtc cgcctccgag ctgcacacgt
    10021 ccgggatcct gggccccgag accctgcggg acctggccca gggcactaag acgctgcagg
    10081 aggtgacgga gatggactcg gtcaagcgct acctggaggg caccagctgc atcgcgggcg
    10141 tcctggtgcc cgccaaggac cagcccggcc gccaggagaa gatgagcatc taccaggcca
    10201 tgtggaaggg cgtgctgcgg cccggcacgg ccctggtgct gctggaggcg caggcggcca
    10261 ccggcttcgt catcgacccc gtgcgcaacc tgaggctgtc ggtggaggag gccgtggccg
    10321 cgggcgtggt gggcggcgag atccaggaga agctgctgtc ggccgagcgc gccgtcaccg
    10381 gctacaccga cccctacacc gggcagcaga tctccctctt ccaggccatg cagaaggacc
    10441 tcatcgtccg ggagcacggc atccgcctgc tggaggccca gatcgccacg ggcggcgtca
    10501 tcgaccccgt gcacagccac cgcgtgcccg tggacgtggc ctaccggcgc ggctacttcg
    10561 acgaggagat gaaccgtgtc ctggccgacc ccagcgacga caccaagggc ttcttcgacc
    10621 ccaacacgca cgagaacctc acgtacgtgc agctgctgcg ccgctgcgtg cccgacccgg
    10681 acaccgggct ctacatgctg cagctggcag gccggggctc cgccgtgcac cagctgagcg
    10741 aggagctgcg ctgtgccctg cgcgacgccc gcgtgacgcc aggctcgggc gccctccagg
    10801 gccagagcgt ctccgtctgg gagctcctct tctaccgcga ggtgtccgag gaccggcgcc
    10861 aggacctgct gagcagatac cgggcgggca cgctgaccgt ggaggagctg ggcgccaccc
    10921 tcacctcgct gctggcccag gcccaggccc aggcccgggc cgaggccgag gccgggagcc
    10981 cgcgcccaga cccccgggag gccctgcgtg cggccaccat ggaggtcaag gtgggccgcc
    11041 tccgggggcg cgcggtgccc gtgtgggacg tgctggcgtc cggctacgtg agcagggccg
    11101 cccgggagga gctgctggcc gagtttggct cggggaccct ggacttgccc gcgctgaccc
    11161 gccggctgac cgccatcatc gaggaggccg aggaggcccc cggggcccgg ccgcagctcc
    11221 aggacgcctg gcgcggcccg cgggagccag ggccagccgg gcgaggggac ggcgactcgg
    11281 ggcgctccca gcgagagggc cagggggagg gcgagaccca ggaggccgcc gccgccaccg
    11341 ccgccgcccg ccgccaggag cagaccctgc gtgatgccac catggaggtg cagcgcgggc
    11401 agttccaggg gcggccggtc tccgtgtggg acgtcctctt ctcctcgtac ctgagcgagg
    11461 cccgccgaga cgagctcctg gcccagcacg cggccggcgc cctgggcctg cccgacctcg
    11521 tcgccgtcct cacccgggtc atcgaggaga cggaggagcg gctcagcaag gtgtccttcc
    11581 gcggcctgag gcgccaggtg tccgcctccg agctgcacac gtccgggatc ctgggccccg
    11641 agaccctgcg ggacctggcc cagggcacta agacgctgca ggaggtgacg gagatggact
    11701 cggtcaagcg ctacctggag ggcaccagct gcatcgcggg cgtcctggtg cccgccaagg
    11761 accagcccgg ccgccaggag aagatgagca tctaccaggc catgtggaag ggcgtgctgc
    11821 ggcccggcac ggccctggtg ctgctggagg cgcaggcggc caccggcttc gtcatcgacc
    11881 ccgtgcgcaa cctgaggctg tcggtggagg aggccgtggc cgcgggcgtg gtgggcggcg
    11941 agatccagga gaagctgctg tcggccgagc gcgccgtcac cggctacacc gacccctaca
    12001 ccgggcagca gatctccctc ttccaggcca tgcagaagga cctcatcgtc cgggagcacg
    12061 gcatccgcct gctggaggcc cagatcgcca cgggcggcgt catcgacccc gtgcacagcc
    12121 accgcgtgcc cgtggacgtg gcctaccggc gcggctactt cgacgaggag atgaaccgtg
    12181 tcctggccga ccccagcgac gacaccaagg gcttcttcga ccccaacacg cacgagaacc
    12241 tcacgtacgt gcagctgctg cgccgctgcg tgcccgaccc ggacaccggg ctctacatgc
    12301 tgcagctggc aggccggggc tccgccgtgc accagctgag cgaggagctg cgctgtgccc
    12361 tgcgcgacgc ccgcgtgacg ccaggctcgg gcgccctcca gggccagagc gtctccgtct
    12421 gggagctcct cttctaccgc gaggtgtccg aggaccggcg ccaggacctg ctgagcagat
    12481 accgggcggg cacgctgacc gtggaggagc tgggcgccac cctcacctcg ctgctggccc
    12541 aggcccaggc ccaggcccgg gccgaggccg aggccgggag cccgcgccca gacccccggg
    12601 aggccctgcg tgcggccacc atggaggtca aggtgggccg cctccggggg cgcgcggtgc
    12661 ccgtgtggga cgtgctggcg tccggctacg tgagcagggc cgcccgggag gagctgctgg
    12721 ccgagtttgg ctcggggacc ctggacttgc ccgcgctgac ccgccggctg accgccatca
    12781 tcgaggaggc cgaggaggcc cccggggccc ggccgcagct ccaggacgcc tggcgcggcc
    12841 cgcgggagcc agggccagcc gggcgagggg acggcgactc ggggcgctcc cagcgagagg
    12901 gccaggggga gggcgagacc caggaggccg ccgccgccac cgccgccgcc cgccgccagg
    12961 agcagaccct gcgtgatgcc accatggagg tgcagcgcgg gcagttccag gggcggccgg
    13021 tctccgtgtg ggacgtcctc ttctcctcgt acctgagcga ggcccgccga gacgagctcc
    13081 tggcccagca cgcggccggc gccctgggcc tgcccgacct cgtcgccgtc ctcacccggg
    13141 tcatcgagga gacggaggag cggctcagca aggtgtcctt ccgcggcctg aggcgccagg
    13201 tgtccgcctc cgagctgcac acgtccggga tcctgggccc cgagaccctg cgggacctgg
    13261 cccagggcac taagacgctg caggaggtga cggagatgga ctcggtcaag cgctacctgg
    13321 agggcaccag ctgcatcgcg ggcgtcctgg tgcccgccaa ggaccagccc ggccaccagg
    13381 agaagatgag catctaccag gccatgtgga agggcgtgct gcggcccggc acggccctgg
    13441 tgctgctgga ggcgcaggcg gccaccggct tcgtcatcga ccccgtgcgc aacctgaggc
    13501 tgtcggtgga ggaggccgtg gccgcgggcg tggtgggcgg cgagatccag gagaagctgc
    13561 tgtcggccga gcgcgccgtc accggctaca ccgaccccta caccgggcag cagatctccc
    13621 tcttccaggc catgcagaag gacctcatcg tccgggagca cggcatccgc ctgctggagg
    13681 cccagatcgc cacgggcggc gtcatcgacc ccgtgcacag ccaccgcgtg cccgtggacg
    13741 tggcctaccg gcgcggctac ttcgacgagg agatgaaccg tgtcctggcc caccccagcg
    13801 acgacaccaa gggcttcttc gaccccaaca cgcacgagaa cctcacgtac gtgcagctgc
    13861 tgcgccgctg cgtgcccgac ccggacaccg ggctctacat gctgcagctg gcaggccggg
    13921 gctccgccgt gcaccagctg agcgaggagc tgcgctgtgc cctgcgcgac gcccgcgtga
    13981 tgccaggctc gggcgccctc cagggccaga gcgtctccgt ctgggagctc ctcttctacc
    14041 gcgaggtgtc cgaggaccgg cgccaggacc tgctgagcag ataccgggcg ggcacgctga
    14101 ccgtggagga gctgggcgcc accctcacct cgctgctggc ccaggcccag gcccaggccc
    14161 gggccgaggc cgaggccgag gccgggagcc cgcgcccaga cccccgggag gccctgcgtg
    14221 cggccaccat ggaggtcaag gtgggccgcc tccgggggcg cgcggtgccc gtgtgggacg
    14281 tgctggcgtc cggctacgtg agcggggccg cccgggagga gctgctggcc gagtttggct
    14341 cggggaccct ggacttgccc gcgctgaccc gccggctgac cgccatcatc gaggaggccg
    14401 aggaggcccc cggggcccgg ccgcagctcc aggacgcctg gcgcggcccg cgggagccag
    14461 ggccagccgg gcgaggggac ggcgactcgg ggcgctccca gcgagagggc cagggggagg
    14521 gcgagaccca ggaggccgcc gccgccgccc gccgccagga gcagaccctg cgtgatgcca
    14581 ccatggaggt gcagcgcggg cagttccagg ggcggccggt ctccgtgtgg gacgtcctct
    14641 tctcctcgta cctgagcgag gcccaccgag acgagctcct ggcccagcac gcggccggcg
    14701 ccctgggcct gcccgacctc gtcgccgtcc tcacccgggt catcgaggag acggaggagc
    14761 ggctcagcaa ggtgtccttc cgcggcctga ggcgccaggt gtccgcctcc gagctgcaca
    14821 cgtccgggat cctgggcccc gagaccctgc gggacctggc ccagggcact aagacgctgc
    14881 aggaggtgac ggagatggac tcggtcaagc gctacctgga gggcaccagc tgcatcgcgg
    14941 gcgtcctggt gcccgccaag gaccagcccg gccgccagga gaagatgagc atctaccagg
    15001 ccatgtggaa gggcgtgctg cggcccggca cggccctggt gctgctggag gcgcaggcgg
    15061 ccaccggctt cgtcatcgac cccgtgcgca acctgaggct gtcggtggag gaggccgtgg
    15121 ccgcgggcgt ggtgggcggc gagatccagg agaagctgct gtcggccgag cgcgccgtca
    15181 ccggctacac cgacccctac accgggcagc agatctccct cttccaggcc atgcagaagg
    15241 acctcatcgt ccgggagcac ggcatccgcc tgctggaggc ccagatcgcc acgggcggcg
    15301 tcatcgaccc cgtgcacagc caccgcgtgc ccgtggacgt ggcctaccgg cgcggctact
    15361 tcgacgagga gatgaaccgc gtcctggccg accccagcga cgacaccaag ggcttcttcg
    15421 accccaacac gcacgagaac ctcacgtacc tgcagcttct gcagagggcc accctggacc
    15481 ctgagacggg gctcctattt ctttctctct ctctacagtg actgggcttc ctccgtgcag
    15541 ttttctgcaa ctctggagaa gtggaggcat acttgtgtgt ctgggttgtt tttttttttt
    15601 tttttttttt tgtcattctt taattttgtt gttttaccca ttcgttatct gtggaaaacg
    15661 ttttaagttg tcatgtgaca gaaacttttc ctttgtccat cgaggtgttt cataagtttt
    15721 ttggtgtgtt ttctgggtcg tctatgtgtc atatggtttt acttttctct cctttttcgt
    15781 tttcagaaca tttttctgtc tgttttggat tcactgcttc cattttacag aatgtcactc
    15841 tttagactct cagtccatca tgccatcggg tactcttgtt gcagtgtaat ttttattaca
    15901 tgcggttatt tccctaacga tgtgctattc acgttcatct tcaaactcat tttccatcag
    15961 ccagtgtcta ctatttagtg ccctggctct atttcggtcc tcctccccgg gctttccctg
    16021 gctgctgtgc tggccaaaag catgggcttt attctctcca ttggctgctg ctccacctta
    16081 gaggtgtgac ctcactagcg ttgactgagc gagtctgttg tggagaagaa ctttttgtag
    16141 taatttacta ggaaaaattc tgaacaagta aaatatgaag gaaa
//
