LOCUS       XM_017013890           16180 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens epiplakin 1 (EPPK1), transcript variant X3,
            mRNA.
ACCESSION   XM_017013890
VERSION     XM_017013890.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000008.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017013890.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16180
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
     gene            1..16180
                     /gene="EPPK1"
                     /gene_synonym="EPIPL; EPIPL1"
                     /note="epiplakin 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 14 ESTs, 183 long
                     SRA reads, 11 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 15 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:83481"
                     /db_xref="HGNC:HGNC:15577"
                     /db_xref="MIM:607553"
     CDS             251..15517
                     /gene="EPPK1"
                     /gene_synonym="EPIPL; EPIPL1"
                     /codon_start=1
                     /product="epiplakin isoform X3"
                     /protein_id="XP_016869379.1"
                     /db_xref="GeneID:83481"
                     /db_xref="HGNC:HGNC:15577"
                     /db_xref="MIM:607553"
                     /translation="MSGHTLPPLPVPGTNSTEQASVPRAMAATLGAGTPPRPQARSIA
                     GVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQG
                     LVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGL
                     VDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLDPNTLERLTYHQLLERC
                     VRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAE
                     VRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITG
                     QRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLAL
                     RLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLSQAGSFSDGTHGGLRYEQ
                     LLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPV
                     SLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAKLSATLEQAAATARVTFSGLRDT
                     VTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASVQRYLQGTGCIAGLLLPGSQERL
                     SIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLL
                     SAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPV
                     DVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPL
                     SSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQ
                     REVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPE
                     ALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGT
                     IMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGL
                     IPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSETFPTPD
                     GQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLWD
                     LLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVP
                     AVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASI
                     AQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQA
                     ERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAA
                     ACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPS
                     DTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGR
                     AAALRQVVSAVTTLVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTT
                     TVKEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAA
                     TGFIIDPVENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQ
                     KDLIVREHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTK
                     GFFDPNTHENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKM
                     RVGRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQN
                     QGIKVAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSGCIA
                     GVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVG
                     LVNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGV
                     IDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRP
                     QEDTGWLLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVT
                     EEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSA
                     IITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQA
                     MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERA
                     VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR
                     RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGS
                     AVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTL
                     TVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWD
                     VLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPR
                     EPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAAAARRQEQTLRDATMEVQRGQFQG
                     RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRG
                     LRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAK
                     DQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVV
                     GGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVID
                     PVHSHRVPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDP
                     DTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSED
                     RRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEV
                     KVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAP
                     GARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAARRQEQTLRDATM
                     EVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEE
                     RLSKVSFRGLRCQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSC
                     IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSV
                     EEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA
                     QIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQ
                     LLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWEL
                     LFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPRE
                     ALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTA
                     IIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAA
                     RRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLV
                     AVLTRVIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEM
                     DSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGF
                     VIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDL
                     IVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFF
                     DPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSG
                     ALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAE
                     AEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGT
                     LDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEG
                     ETQEAAAATAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQ
                     HAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLA
                     QGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGHQEKMSIYQAMWKGVLRPGTA
                     LVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQ
                     QISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRV
                     LAHPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRC
                     ALRDARVMPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTS
                     LLAQAQAQARAEAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSG
                     AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGD
                     GDSGRSQREGQGEGETQEAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYL
                     SEAHRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSG
                     ILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQA
                     MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERA
                     VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR
                     RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSLQ"
ORIGIN      
        1 tactcccagg gtgacaggga acattctctg tgcccaggtg gaggagccag accggggggt
       61 gaggcctggc actgctccag gcaggacatc ccagctctta caacgtcatg ggggcagggg
      121 ggcctgccaa ggagagcctt gaagacccct ggacccagca gacacacgac gtgaagcagc
      181 gtccccagga agctgagcag acaaggacag aggtggacct cagcaggctc tgcataacca
      241 gccgtgtgtg atgagtggcc acaccttgcc tcctcttccc gtcccaggca ccaacagcac
      301 agagcaggcc agtgtaccca gagccatggc agccacgctg ggagccggca cgccccccag
      361 gccccaggcc aggagcatag ctggggtgta tgtggaggcc tcgggccagg cccagagtgt
      421 ctacgccgcc atggagcagg gcctcctgcc tgctgggctc gggcaggctc tgctagaggc
      481 ccaggcagcc actgggggcc tggtggacct cgcccggggc cagctgctcc ctgtgtccaa
      541 ggccctgcag cagggtctgg tggggctgga gctgaaggag aagctgctgg ccgctgagcg
      601 tgccactacg ggctatcctg acccctacgg cggtgagaag ctggccctct ttcaggccat
      661 cgggaaggag gttgtggaca gggccctggg gcagagctgg ctggaggtcc aactggccac
      721 tgggggcctg gtggaccccg cccagggagt gctcgtggcc cctgagccag cctgccacca
      781 gggcctcctg gaccgggaga catggcacaa gctgtcagag cttgagcctg gcacaggtga
      841 cctgcgcttc ctcgacccca acacgctgga gcggctgaca taccaccagc tgctggaaag
      901 gtgtgtgcgt gcccccggct cggggctagc cttgctgccc ctcaagatca ccttccgctc
      961 catgggcggg gcggtgagtg cagctgagct gctggaggtg ggcatcctgg acgagcaggc
     1021 tgtgcagggt ctgcgggagg gcaggctggc cgcagtggac gtgagtgcac gtgccgaggt
     1081 gcggcgctac ctggagggta ccggcagcgt ggccggggtt gtcctgctgc ccgaaggcca
     1141 caagaagagc tttttccagg ctgccaccga gcacctgctc ccaatgggca ccgcgctgcc
     1201 actcctagag gcccaggctg ccacccacac cctggtggac cccatcacag gccagcggct
     1261 gtgggtagac gaggcagtca gggcgggcct ggtcagccca gagctccatg agcagctcct
     1321 ggtggccgag caggccgtga cagggcacca cgaccccttc agtggctccc aaatccccct
     1381 tttccaggcc atgaagaagg ggctagtgga caggccactg gcactgcggc tcttggatgc
     1441 ccagctggcc acaggcgggc tggtctgtcc agcacgcagg ctccggctgc ccctggaggc
     1501 cgccctgcgc tgcggctgcc tggatgaaga cactcagcgg cagctctcgc aggctggcag
     1561 cttctcagac ggcacgcacg gcggcctgcg ctatgaacag ctgctggccc tctgtgtcac
     1621 cgacccagag accgggcttg ccttcctgcc actctcaggg ggaccccggg gaggggagcc
     1681 ccagggaccc ccattcatca agtacagcac tcggcaggcc ctgagcacgg ccacagccac
     1741 cgtctctgtg gggaagttcc ggggccggcc cgtgtccctc tgggagctgc tcttctctga
     1801 ggccatctcc tcagagcaga gggcgatgct ggcccagcag taccaggaag ggaccctctc
     1861 cgtggagaag ctggccgcta agctgagcgc caccctcgag caggctgcag ccactgccag
     1921 ggtcaccttt tctgggctga gggacaccgt gacaccagga gagctgctga aagccgagat
     1981 catcgaccag gacctgtacg agcggctgga gcatggacag gccacagcca aggatgtggg
     2041 cagcctggcc tcggtgcaga ggtacctgca gggtacgggc tgcattgctg gcctgctgct
     2101 ccctggctcc caggaacgcc tgagcatcta tgaggcccga tgcaaggggc tcctccggcc
     2161 cggcactgcc ctcatccttc tggaggcaca agctgccaca ggcttcatca tcgacccaaa
     2221 agcaaacaag gggcactccg ttgaggaggc actgagggct gctgtcattg ggcctgatgt
     2281 gttcgcgaag ctgctgtcgg ctgagcgcgc tgtcactggc tacactgacc cctacaccgg
     2341 gcagcagatc tccctcttcc aggccatgca gaagggcctc atcgtccggg agcacggcat
     2401 ccgcctgctg gaggcccaga tcgccacggg cggcgtcatc gaccccgtgc acagccaccg
     2461 cgtgcccgtg gacgtggcct accggcgcgg ctacttcgat cagatgctga acttgatcct
     2521 gttggaccct tctgacgaca ccaagggctt cttcgacccc aacacgcacg agaacctcac
     2581 gtacctgcag cttctggagc gctgtgtgcg tgaccccgag acgggcctgt acctcctgcc
     2641 actcagcagc acgcagtccc cgctggtgga cagtgccacc cagcaggcct tccagaacct
     2701 gctgctctcc gtgaagtatg gacggtttca ggggcagagg gtctccgcgt gggagctgat
     2761 caactctgag tacttcagcg agggccgcag gaggcagctg ctgcgtcgct accggcagcg
     2821 cgaggtcacg ctggggcagg tggcaaagct gctggaggcg gagacgcaga gacaggcgga
     2881 catcatgctg cccgcactgc ggagccgggt caccgtccac cagctcctgg aggccggtat
     2941 cattgaccag cagctgttgg accaagtgct ggccgggaca atcagcccgg aggccctcct
     3001 actcatggac ggcgtccgca ggtacctgtg cggcctggga gctgtgggcg gtgtgcggct
     3061 gctgccctct ggccagcggc tcagcctcta ccaggccatg aggcagaagc tgctggggcc
     3121 cagggtggcc ctggccctgc tggaggccca ggcggccacc ggaaccatca tggaccctca
     3181 cagcccagag agcctctcgg tggatgaggc cgtgcgcagg ggtgtggtgg ggccggagct
     3241 gtatggcagg ctgaagcggg ctgagggtgc cattgctggc ttcagagacc ccttctctgg
     3301 gaagcaggtg tctgtgttcc aggccatgaa gaaaggtctc atcccttggg agcaagctgc
     3361 ccgcctcctg gaggctcaag tggccacagg agggatcatt gaccccacca gccaccacca
     3421 cctccccatg ccagtggcca ttcagcgtgg ctatgttgac caggagatgg agacagcctt
     3481 gtccagctcc tccgaaacct tccccacacc ggacggccag gggcgcacga gctatgccca
     3541 gctcctggag gagtgcccca gggatgagac ttctggcctt cacctcctgc ccctgccaga
     3601 aagtgctcct gccctcccca ccgaggagca ggtccagagg agcctgcagg ccgtgccggg
     3661 ggccaaggat ggcacatccc tctgggacct gctcagctcc tgccacttca ccgaggagca
     3721 acggaggggc ctgctggagg acgtgcagga ggggaggacc actgtgccac agctgctagc
     3781 ctctgtgcag aggtgggtac aggagaccaa gctcctggcc caggcccgcg tcatggtgcc
     3841 cggcccacgg ggtgaggtac ccgctgtctg gctgctggat gctggcatca tcacccagga
     3901 gacccttgag gccctggctc agggcacgca gtcgcccgcc caggtcgccg agcagccggc
     3961 ggtgaaggcc tgcctgtggg gcacaggctg cgtggccggt gtgctgctac agccctctgg
     4021 ggccaaggcc agcatcgccc aggccgtgag ggatggcctc ctgcccacag gcctgggcca
     4081 gaggctgctg gaagcccagg tggcatctgg cttccttgtt gaccccctga acaaccagag
     4141 actgtcagtg gaggacgcgg ttaaggtcgg cctggtgggc agggagctga gtgagcagct
     4201 cgggcaggcc gagagggcgg cggccgggta cccagatccc tactctaggg cctccctctc
     4261 tctgtggcag gccatggaga aggggctcgt gccacagaac gagggcttgc ccctcctgca
     4321 ggtgcagctg gccacagggg gtgtggtgga ccctgtccac ggggtgcacc tgccccaggc
     4381 ggcagcctgc agactcggcc ttctggacac acagacgagc caggtgctga ctgcagttga
     4441 caaggacaac aagttcttct ttgaccccag tgcgcgggac caggtgacct accagcagct
     4501 cagggagcgc tgcgtgtgcg actccgagac cggattgttg ctgttgccac tgccctcaga
     4561 cacagtgctt gaggtggacg accacaccgc ggtggctctg agggccatga aggtgcccgt
     4621 cagcacaggg aggtttaagg ggtgtagcgt gtcactctgg gacctgctgc tctccgaata
     4681 cgttggcgct gacaagcggc gggagctggt ggcactctgt cggtctggga gggctgcggc
     4741 cctgcggcag gtggtcagcg cagtcaccac cctggtcgag gctgcagaga ggcagcccct
     4801 gcaggccacc ttcagagggc tccggaagca ggtgtcagcc agggacctgt tcagggcgca
     4861 gctgatcagc aggaagacgc tggacgagct gagccagggg acaacgactg tgaaggaggt
     4921 ggcggagatg gacagcgtga agcggtccct ggagggaggc aacttcattg ccggggtcct
     4981 tatccagggc acccaggaga ggatgagcat cccagaggcc ctgaggaggc acatcctgcg
     5041 gcctggcaca gccctggtgc tgctggaggc acaggcagct accggcttca tcatcgaccc
     5101 cgtggagaac cggaagctga ccgtggagga ggcgttcaaa gcaggaatgt tcgggaaaga
     5161 aacctacgtg aagctgctgt cggccgagcg cgccgtcacc ggctacaccg acccctatac
     5221 cgggcagcag atctccctct tccaggccat gcagaaggac ctcatcgtcc gggagcacgg
     5281 catccgcctg ctggaggccc agatcgccac gggcggcatc atcgaccccg tgcacagcca
     5341 ccgcgtgccc gtggacgtgg cctaccgctg cggctacttc gacgaggaga tgaaccgcat
     5401 cctggcggac cccagcgacg acaccaaggg cttcttcgac cccaacacgc acgagaacct
     5461 cacgtacctg cagcttctgg agcgctgtgt ggaggacccc gagacgggcc tgtacctgct
     5521 acaaatcata aagaaaggag aaaactacgt gtacatcaat gaggccacga gacacgtgtt
     5581 gcaatccaga actgcaaaaa tgcgcgtggg gaggtttgct gaccaggtgg tctctttctg
     5641 ggacctgctg tcctctccat acttcacaga ggacaggaag cgggagctca tccaggagta
     5701 tggagcccag agtgggggcc tggagaaatt gctggaaatc atcaccacga caattgaaga
     5761 aacagagacg caaaaccaag gcatcaaagt ggcggccatc agaggggagg tgacagctgc
     5821 agacctgttc aactccaggg tcatcgatca gaagaccctg cacacacttc gtgtggggag
     5881 gactggggga caggcactca gcacgctgga gtgtgtgaag ccctatctgg aaggcagcgg
     5941 ctgcattgcg ggggtcacgg tgccctccac cagggaggtc atgagcctcc atgaggccag
     6001 caggaaggag ctcatccctg cagcatttgc gacttggctg ctggaggcgc aggccgccac
     6061 cgggttcctc ctggacccct gcacccgcca gaagctctct gtggatgagg ctgtggatgt
     6121 gggcctggtg aacgaggagc tgcgggagag gctcctgaag gctgaaagag ctgccacggg
     6181 ctacagggat ccggccacag gagacacgat cccgctgttc caggccatgc agaagcagct
     6241 catcgagaag gcggaggcac tgaggctgct ggaggtgcag gtggccacgg ggggtgtcat
     6301 cgacccacag caccaccacc ggctcccact ggaaacagcc tacagacggg gctgtctgca
     6361 caaggacatc tatgcgctca tttccgacca gaagcacatg aggaaacggt ttgtggaccc
     6421 gaacacgcaa gagaaggtct cgtaccgaga gctgcaggag aggtgccgcc cacaagagga
     6481 cacgggctgg ctgctgttcc cagtgaacaa ggctgcacgg gactccgagc acatcgatga
     6541 cgagacgaga agggccctgg aggcagagca agtggaaatc acagtgggaa ggttcagagg
     6601 ccagaaacca acactgtggg cactactgaa ttccgaatac gtgacagagg agaagaagct
     6661 ccagctggtg aggatgtata gaacacacac cagacgggca ctgcagacgg tagcgcagct
     6721 catcttagag ttgatcgaga agcaggaaac cagcaacaaa cacctgtggt tccaaggaat
     6781 tagacgacag atcacagctt ctgaactcct cagctcagcc ataatcacgg aggaaatgct
     6841 ccaggacctg gaaacgggac ggagcacgac gcaagagctc atggaggacg accgcgtcaa
     6901 gcgctacctg gagggcacca gctgcatcgc gggcgtcctg gtgcccgcca aggaccagcc
     6961 cggccgccag gagaagatga gcatctacca ggccatgtgg aagggcgtgc tgcggcccgg
     7021 cacggccctg gtgctgctgg aggcgcaggc ggccaccggc ttcgtcatcg accccgtgcg
     7081 caacctgagg ctgtcggtgg aggaggccgt ggccgcgggc gtggtgggcg gcgagatcca
     7141 ggagaagctg ctgtcggccg agcgcgccgt caccggctac accgacccct acaccgggca
     7201 gcagatctcc ctcttccagg ccatgcagaa ggacctcatc gtccgggagc acggcatccg
     7261 cctgctggag gcccagatcg ccacgggcgg cgtcatcgac cccgtgcaca gccaccgcgt
     7321 gcccgtggac gtggcctacc ggcgcggcta cttcgacgag gagatgaacc gtgtcctggc
     7381 cgaccccagc gacgacacca agggcttctt cgaccccaac acgcacgaga acctcacgta
     7441 cgtgcagctg ctgcgccgct gcgtgcccga cccggacacc gggctctaca tgctgcagct
     7501 ggcaggccgg ggctccgccg tgcaccagct gagcgaggag ctgcgctgtg ccctgcgcga
     7561 cgcccgcgtg acgccaggct cgggcgccct ccagggccag agcgtctccg tctgggagct
     7621 cctcttctac cgcgaggtgt ccgaggaccg gcgccaggac ctgctgagca gataccgggc
     7681 gggcacgctg accgtggagg agctgggcgc caccctcacc tcgctgctgg cccaggccca
     7741 ggcccaggcc cgggccgagg ccgaggccgg gagcccgcgc ccagaccccc gggaggccct
     7801 gcgtgcggcc accatggagg tcaaggtggg ccgcctccgg gggcgcgcgg tgcccgtgtg
     7861 ggacgtgctg gcgtccggct acgtgagcag ggccgcccgg gaggagctgc tggccgagtt
     7921 tggctcgggg accctggact tgcccgcgct gacccgccgg ctgaccgcca tcatcgagga
     7981 ggccgaggag gcccccgggg cccggccgca gctccaggac gcctggcgcg gcccgcggga
     8041 gccagggcca gccgggcgag gggacggcga ctcggggcgc tcccagcgag agggccaggg
     8101 ggagggcgag acccaggagg ccgccgccgc cgccgccgcc gccgccgccc gccgccagga
     8161 gcagaccctg cgtgatgcca ccatggaggt gcagcgcggg cagttccagg ggcggccggt
     8221 ctccgtgtgg gacgtcctct tctcctcgta cctgagcgag gcccgccgag acgagctcct
     8281 ggcccagcac gcggccggcg ccctgggcct gcccgacctc gtcgccgtcc tcacccgggt
     8341 catcgaggag accgaggagc ggctcagcaa ggtgtccttc cgcggcctga ggcgccaggt
     8401 gtccgcctcc gagctgcaca cgtccgggat cctgggcccc gagaccctgc gggacctggc
     8461 ccagggcact aagacgctgc aggaggtgac ggagatggac tcggtcaagc gctacctgga
     8521 gggcaccagc tgcatcgcgg gcgtcctggt gcccgccaag gaccagcccg gccgccagga
     8581 gaagatgagc atctaccagg ccatgtggaa gggcgtgctg cggcccggca cggccctggt
     8641 gctgctggag gcgcaggcgg ccaccggctt cgtcatcgac cccgtgcgca acctgaggct
     8701 gtcggtggag gaggccgtgg ccgcgggcgt ggtgggcggc gagatccagg agaagctgct
     8761 gtcggccgag cgcgccgtca ccggctacac cgacccctac accgggcagc agatctccct
     8821 cttccaggcc atgcagaagg acctcatcgt ccgggagcac ggcatccgcc tgctggaggc
     8881 ccagatcgcc acgggcggcg tcatcgaccc cgtgcacagc caccgcgtgc ccgtggacgt
     8941 ggcctaccag cgcggctact tcgacgagga gatgaaccgt gtcctggccg accccagcga
     9001 cgacaccaag ggcttcttcg accccaacac gcacgagaac ctcacgtacg tgcagctgct
     9061 gcgccgctgc gtgcccgacc cggacaccgg gctctacatg ctgcagctgg caggccgggg
     9121 ctccgccgtg caccagctga gcgaggagct gcgctgtgcc ctgcgcgacg cccgcgtgac
     9181 gccaggctcg ggcgccctcc agggccagag cgtctccgtc tgggagctcc tcttctaccg
     9241 cgaggtgtcc gaggaccggc gccaggacct gctgagcaga taccgggcgg gcacgctgac
     9301 cgtggaagag ctgggcgcca ccctcacctc gctgctggcc caggcccagg cccaggcccg
     9361 ggccgaggcc gaggccggga gcccgcgccc agacccccgg gaggccctgc gtgcggccac
     9421 catggaggtc aaggtgggcc gcctccgggg gcgcgcggtg cccgtgtggg acgtgctggc
     9481 gtccggctac gtgagcaggg ccgcccggga ggagctgctg gccgagtttg gctcggggac
     9541 cctggacttg cccgcgctga cccgccggct gaccgccatc atcgaggagg ccgaggaggc
     9601 ccccggggcc cggccgcagc tccaggacgc ctggcgcggc ccgcgggagc cagggccagc
     9661 cgggcgaggg gacggcgact cggggcgctc ccagcgagag ggccaggggg agggcgagac
     9721 ccaggaggcc gccgccgccg cccgccgcca ggagcagacc ctgcgtgatg ccaccatgga
     9781 ggtgcagcgc gggcagttcc aggggcggcc ggtctccgtg tgggacgtcc tcttctcctc
     9841 gtacctgagc gaggcccgcc gagacgagct cctggcccag cacgcggccg gcgccctggg
     9901 cctgcccgac ctcgtcgccg tcctcacccg ggtcatcgag gagacggagg agcggctcag
     9961 caaggtgtcc ttccgcggcc tgaggtgcca ggtgtccgcc tccgagctgc acacgtccgg
    10021 gatcctgggc cccgagaccc tgcgggacct ggcccagggc actaagacgc tgcaggaggt
    10081 gacggagatg gactcggtca agcgctacct ggagggcacc agctgcatcg cgggcgtcct
    10141 ggtgcccgcc aaggaccagc ccggccgcca ggagaagatg agcatctacc aggccatgtg
    10201 gaagggcgtg ctgcggcccg gcacggccct ggtgctgctg gaggcgcagg cggccaccgg
    10261 cttcgtcatc gaccccgtgc gcaacctgag gctgtcggtg gaggaggccg tggccgcggg
    10321 cgtggtgggc ggcgagatcc aggagaagct gctgtcggcc gagcgcgccg tcaccggcta
    10381 caccgacccc tacaccgggc agcagatctc cctcttccag gccatgcaga aggacctcat
    10441 cgtccgggag cacggcatcc gcctgctgga ggcccagatc gccacgggcg gcgtcatcga
    10501 ccccgtgcac agccaccgcg tgcccgtgga cgtggcctac cggcgcggct acttcgacga
    10561 ggagatgaac cgtgtcctgg ccgaccccag cgacgacacc aagggcttct tcgaccccaa
    10621 cacgcacgag aacctcacgt acgtgcagct gctgcgccgc tgcgtgcccg acccggacac
    10681 cgggctctac atgctgcagc tggcaggccg gggctccgcc gtgcaccagc tgagcgagga
    10741 gctgcgctgt gccctgcgcg acgcccgcgt gacgccaggc tcgggcgccc tccagggcca
    10801 gagcgtctcc gtctgggagc tcctcttcta ccgcgaggtg tccgaggacc ggcgccagga
    10861 cctgctgagc agataccggg cgggcacgct gaccgtggag gagctgggcg ccaccctcac
    10921 ctcgctgctg gcccaggccc aggcccaggc ccgggccgag gccgaggccg ggagcccgcg
    10981 cccagacccc cgggaggccc tgcgtgcggc caccatggag gtcaaggtgg gccgcctccg
    11041 ggggcgcgcg gtgcccgtgt gggacgtgct ggcgtccggc tacgtgagca gggccgcccg
    11101 ggaggagctg ctggccgagt ttggctcggg gaccctggac ttgcccgcgc tgacccgccg
    11161 gctgaccgcc atcatcgagg aggccgagga ggcccccggg gcccggccgc agctccagga
    11221 cgcctggcgc ggcccgcggg agccagggcc agccgggcga ggggacggcg actcggggcg
    11281 ctcccagcga gagggccagg gggagggcga gacccaggag gccgccgccg ccaccgccgc
    11341 cgcccgccgc caggagcaga ccctgcgtga tgccaccatg gaggtgcagc gcgggcagtt
    11401 ccaggggcgg ccggtctccg tgtgggacgt cctcttctcc tcgtacctga gcgaggcccg
    11461 ccgagacgag ctcctggccc agcacgcggc cggcgccctg ggcctgcccg acctcgtcgc
    11521 cgtcctcacc cgggtcatcg aggagacgga ggagcggctc agcaaggtgt ccttccgcgg
    11581 cctgaggcgc caggtgtccg cctccgagct gcacacgtcc gggatcctgg gccccgagac
    11641 cctgcgggac ctggcccagg gcactaagac gctgcaggag gtgacggaga tggactcggt
    11701 caagcgctac ctggagggca ccagctgcat cgcgggcgtc ctggtgcccg ccaaggacca
    11761 gcccggccgc caggagaaga tgagcatcta ccaggccatg tggaagggcg tgctgcggcc
    11821 cggcacggcc ctggtgctgc tggaggcgca ggcggccacc ggcttcgtca tcgaccccgt
    11881 gcgcaacctg aggctgtcgg tggaggaggc cgtggccgcg ggcgtggtgg gcggcgagat
    11941 ccaggagaag ctgctgtcgg ccgagcgcgc cgtcaccggc tacaccgacc cctacaccgg
    12001 gcagcagatc tccctcttcc aggccatgca gaaggacctc atcgtccggg agcacggcat
    12061 ccgcctgctg gaggcccaga tcgccacggg cggcgtcatc gaccccgtgc acagccaccg
    12121 cgtgcccgtg gacgtggcct accggcgcgg ctacttcgac gaggagatga accgtgtcct
    12181 ggccgacccc agcgacgaca ccaagggctt cttcgacccc aacacgcacg agaacctcac
    12241 gtacgtgcag ctgctgcgcc gctgcgtgcc cgacccggac accgggctct acatgctgca
    12301 gctggcaggc cggggctccg ccgtgcacca gctgagcgag gagctgcgct gtgccctgcg
    12361 cgacgcccgc gtgacgccag gctcgggcgc cctccagggc cagagcgtct ccgtctggga
    12421 gctcctcttc taccgcgagg tgtccgagga ccggcgccag gacctgctga gcagataccg
    12481 ggcgggcacg ctgaccgtgg aggagctggg cgccaccctc acctcgctgc tggcccaggc
    12541 ccaggcccag gcccgggccg aggccgaggc cgggagcccg cgcccagacc cccgggaggc
    12601 cctgcgtgcg gccaccatgg aggtcaaggt gggccgcctc cgggggcgcg cggtgcccgt
    12661 gtgggacgtg ctggcgtccg gctacgtgag cagggccgcc cgggaggagc tgctggccga
    12721 gtttggctcg gggaccctgg acttgcccgc gctgacccgc cggctgaccg ccatcatcga
    12781 ggaggccgag gaggcccccg gggcccggcc gcagctccag gacgcctggc gcggcccgcg
    12841 ggagccaggg ccagccgggc gaggggacgg cgactcgggg cgctcccagc gagagggcca
    12901 gggggagggc gagacccagg aggccgccgc cgccaccgcc gccgcccgcc gccaggagca
    12961 gaccctgcgt gatgccacca tggaggtgca gcgcgggcag ttccaggggc ggccggtctc
    13021 cgtgtgggac gtcctcttct cctcgtacct gagcgaggcc cgccgagacg agctcctggc
    13081 ccagcacgcg gccggcgccc tgggcctgcc cgacctcgtc gccgtcctca cccgggtcat
    13141 cgaggagacg gaggagcggc tcagcaaggt gtccttccgc ggcctgaggc gccaggtgtc
    13201 cgcctccgag ctgcacacgt ccgggatcct gggccccgag accctgcggg acctggccca
    13261 gggcactaag acgctgcagg aggtgacgga gatggactcg gtcaagcgct acctggaggg
    13321 caccagctgc atcgcgggcg tcctggtgcc cgccaaggac cagcccggcc accaggagaa
    13381 gatgagcatc taccaggcca tgtggaaggg cgtgctgcgg cccggcacgg ccctggtgct
    13441 gctggaggcg caggcggcca ccggcttcgt catcgacccc gtgcgcaacc tgaggctgtc
    13501 ggtggaggag gccgtggccg cgggcgtggt gggcggcgag atccaggaga agctgctgtc
    13561 ggccgagcgc gccgtcaccg gctacaccga cccctacacc gggcagcaga tctccctctt
    13621 ccaggccatg cagaaggacc tcatcgtccg ggagcacggc atccgcctgc tggaggccca
    13681 gatcgccacg ggcggcgtca tcgaccccgt gcacagccac cgcgtgcccg tggacgtggc
    13741 ctaccggcgc ggctacttcg acgaggagat gaaccgtgtc ctggcccacc ccagcgacga
    13801 caccaagggc ttcttcgacc ccaacacgca cgagaacctc acgtacgtgc agctgctgcg
    13861 ccgctgcgtg cccgacccgg acaccgggct ctacatgctg cagctggcag gccggggctc
    13921 cgccgtgcac cagctgagcg aggagctgcg ctgtgccctg cgcgacgccc gcgtgatgcc
    13981 aggctcgggc gccctccagg gccagagcgt ctccgtctgg gagctcctct tctaccgcga
    14041 ggtgtccgag gaccggcgcc aggacctgct gagcagatac cgggcgggca cgctgaccgt
    14101 ggaggagctg ggcgccaccc tcacctcgct gctggcccag gcccaggccc aggcccgggc
    14161 cgaggccgag gccgaggccg ggagcccgcg cccagacccc cgggaggccc tgcgtgcggc
    14221 caccatggag gtcaaggtgg gccgcctccg ggggcgcgcg gtgcccgtgt gggacgtgct
    14281 ggcgtccggc tacgtgagcg gggccgcccg ggaggagctg ctggccgagt ttggctcggg
    14341 gaccctggac ttgcccgcgc tgacccgccg gctgaccgcc atcatcgagg aggccgagga
    14401 ggcccccggg gcccggccgc agctccagga cgcctggcgc ggcccgcggg agccagggcc
    14461 agccgggcga ggggacggcg actcggggcg ctcccagcga gagggccagg gggagggcga
    14521 gacccaggag gccgccgccg ccgcccgccg ccaggagcag accctgcgtg atgccaccat
    14581 ggaggtgcag cgcgggcagt tccaggggcg gccggtctcc gtgtgggacg tcctcttctc
    14641 ctcgtacctg agcgaggccc accgagacga gctcctggcc cagcacgcgg ccggcgccct
    14701 gggcctgccc gacctcgtcg ccgtcctcac ccgggtcatc gaggagacgg aggagcggct
    14761 cagcaaggtg tccttccgcg gcctgaggcg ccaggtgtcc gcctccgagc tgcacacgtc
    14821 cgggatcctg ggccccgaga ccctgcggga cctggcccag ggcactaaga cgctgcagga
    14881 ggtgacggag atggactcgg tcaagcgcta cctggagggc accagctgca tcgcgggcgt
    14941 cctggtgccc gccaaggacc agcccggccg ccaggagaag atgagcatct accaggccat
    15001 gtggaagggc gtgctgcggc ccggcacggc cctggtgctg ctggaggcgc aggcggccac
    15061 cggcttcgtc atcgaccccg tgcgcaacct gaggctgtcg gtggaggagg ccgtggccgc
    15121 gggcgtggtg ggcggcgaga tccaggagaa gctgctgtcg gccgagcgcg ccgtcaccgg
    15181 ctacaccgac ccctacaccg ggcagcagat ctccctcttc caggccatgc agaaggacct
    15241 catcgtccgg gagcacggca tccgcctgct ggaggcccag atcgccacgg gcggcgtcat
    15301 cgaccccgtg cacagccacc gcgtgcccgt ggacgtggcc taccggcgcg gctacttcga
    15361 cgaggagatg aaccgcgtcc tggccgaccc cagcgacgac accaagggct tcttcgaccc
    15421 caacacgcac gagaacctca cgtacctgca gcttctgcag agggccaccc tggaccctga
    15481 gacggggctc ctatttcttt ctctctctct acagtgactg ggcttcctcc gtgcagtttt
    15541 ctgcaactct ggagaagtgg aggcatactt gtgtgtctgg gttgtttttt tttttttttt
    15601 tttttttgtc attctttaat tttgttgttt tacccattcg ttatctgtgg aaaacgtttt
    15661 aagttgtcat gtgacagaaa cttttccttt gtccatcgag gtgtttcata agttttttgg
    15721 tgtgttttct gggtcgtcta tgtgtcatat ggttttactt ttctctcctt tttcgttttc
    15781 agaacatttt tctgtctgtt ttggattcac tgcttccatt ttacagaatg tcactcttta
    15841 gactctcagt ccatcatgcc atcgggtact cttgttgcag tgtaattttt attacatgcg
    15901 gttatttccc taacgatgtg ctattcacgt tcatcttcaa actcattttc catcagccag
    15961 tgtctactat ttagtgccct ggctctattt cggtcctcct ccccgggctt tccctggctg
    16021 ctgtgctggc caaaagcatg ggctttattc tctccattgg ctgctgctcc accttagagg
    16081 tgtgacctca ctagcgttga ctgagcgagt ctgttgtgga gaagaacttt ttgtagtaat
    16141 ttactaggaa aaattctgaa caagtaaaat atgaaggaaa
//
