LOCUS       NM_031308              16005 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens epiplakin 1 (EPPK1), mRNA.
ACCESSION   NM_031308 XM_372063
VERSION     NM_031308.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 16005)
  AUTHORS   Benz,C., Ali,M., Krystkowiak,I., Simonetti,L., Sayadi,A.,
            Mihalic,F., Kliche,J., Andersson,E., Jemth,P., Davey,N.E. and
            Ivarsson,Y.
  TITLE     Proteome-scale mapping of binding sites in the unstructured regions
            of the human proteome
  JOURNAL   Mol Syst Biol 18 (1), e10584 (2022)
   PUBMED   35044719
REFERENCE   2  (bases 1 to 16005)
  AUTHORS   Ma,D., Pan,Z., Chang,Q., Zhang,J.J., Liu,X., Hua,N. and Li,G.H.
  TITLE     KLF5-mediated Eppk1 expression promotes cell proliferation in
            cervical cancer via the p38 signaling pathway
  JOURNAL   BMC Cancer 21 (1), 377 (2021)
   PUBMED   33827480
  REMARK    GeneRIF: KLF5-mediated Eppk1 expression promotes cell proliferation
            in cervical cancer via the p38 signaling pathway.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 16005)
  AUTHORS   Kokado,M., Okada,Y., Miyamoto,T., Yamanaka,O. and Saika,S.
  TITLE     Effects of epiplakin-knockdown in cultured corneal epithelial cells
  JOURNAL   BMC Res Notes 9, 278 (2016)
   PUBMED   27206504
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 16005)
  AUTHORS   Hilger,A., Schramm,C., Pennimpede,T., Wittler,L., Dworschak,G.C.,
            Bartels,E., Engels,H., Zink,A.M., Degenhardt,F., Muller,A.M.,
            Schmiedeke,E., Grasshoff-Derr,S., Marzheuser,S., Hosie,S.,
            Holland-Cunz,S., Wijers,C.H., Marcelis,C.L., van Rooij,I.A.,
            Hildebrandt,F., Herrmann,B.G., Nothen,M.M., Ludwig,M., Reutter,H.
            and Draaken,M.
  TITLE     De novo microduplications at 1q41, 2q37.3, and 8q24.3 in patients
            with VATER/VACTERL association
  JOURNAL   Eur J Hum Genet 21 (12), 1377-1382 (2013)
   PUBMED   23549274
REFERENCE   5  (bases 1 to 16005)
  AUTHORS   Jang,S.I., Kalinin,A., Takahashi,K., Marekov,L.N. and Steinert,P.M.
  TITLE     Characterization of human epiplakin: RNAi-mediated epiplakin
            depletion leads to the disruption of keratin and vimentin IF
            networks
  JOURNAL   J Cell Sci 118 (Pt 4), 781-793 (2005)
   PUBMED   15671067
  REMARK    GeneRIF: Epiplakin may be a cytolinker involved in maintaining the
            integrity of intermediate filaments networks in simple epithelial
            cells.
REFERENCE   6  (bases 1 to 16005)
  AUTHORS   Takeo,N., Wang,W., Matsuo,N., Sumiyoshi,H., Yoshioka,H. and
            Fujiwara,S.
  TITLE     Structure and heterogeneity of the human gene for epiplakin (EPPK1)
  JOURNAL   J Invest Dermatol 121 (5), 1224-1226 (2003)
   PUBMED   14708632
REFERENCE   7  (bases 1 to 16005)
  AUTHORS   Spazierer,D., Fuchs,P., Proll,V., Janda,L., Oehler,S., Fischer,I.,
            Hauptmann,R. and Wiche,G.
  TITLE     Epiplakin gene analysis in mouse reveals a single exon encoding a
            725-kDa protein with expression restricted to epithelial tissues
  JOURNAL   J Biol Chem 278 (34), 31657-31666 (2003)
   PUBMED   12791695
REFERENCE   8  (bases 1 to 16005)
  AUTHORS   Leung,C.L., Green,K.J. and Liem,R.K.
  TITLE     Plakins: a family of versatile cytolinker proteins
  JOURNAL   Trends Cell Biol 12 (1), 37-45 (2002)
   PUBMED   11854008
  REMARK    Review article
REFERENCE   9  (bases 1 to 16005)
  AUTHORS   Fujiwara,S., Takeo,N., Otani,Y., Parry,D.A., Kunimatsu,M., Lu,R.,
            Sasaki,M., Matsuo,N., Khaleduzzaman,M. and Yoshioka,H.
  TITLE     Epiplakin, a novel member of the Plakin family originally
            identified as a 450-kDa human epidermal autoantigen. Structure and
            tissue localization
  JOURNAL   J Biol Chem 276 (16), 13340-13347 (2001)
   PUBMED   11278896
REFERENCE   10 (bases 1 to 16005)
  AUTHORS   Fujiwara,S., Kohno,K., Iwamatsu,A., Naito,I. and Shinkai,H.
  TITLE     Identification of a 450-kDa human epidermal autoantigen as a new
            member of the plectin family
  JOURNAL   J Invest Dermatol 106 (5), 1125-1130 (1996)
   PUBMED   8618051
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC109322.16, BP313273.1,
            AC234917.3 and AL137725.1.
            
            On Aug 31, 2019 this sequence version replaced NM_031308.3.
            
            Summary: The protein encoded by this gene belongs to the plakin
            family of proteins, which play a role in the organization of
            cytoskeletal architecture. This family member is composed of
            several highly homologous plakin repeats. It may function to
            maintain the integrity of keratin intermediate filament networks in
            epithelial cells. Studies of the orthologous mouse protein suggest
            that it accelerates keratinocyte migration during wound healing.
            [provided by RefSeq, Oct 2013].
            
            Sequence Note: The 5'-most translation start codon is selected for
            this RefSeq due to conservation in other species. The use of an
            alternative downstream start codon, which has a stronger Kozak
            signal, would result in a protein that is 25 aa shorter at the
            N-terminus. Due to leaky scanning by ribosomes, it is possible that
            both start codons are used. The use of the downstream start codon
            is assumed in the literature (e.g., PMID:11278896), but there is no
            experimental evidence indicating which start codon is
            preferentially used in vivo. This RefSeq was created from
            transcript and genomic sequence data to make the sequence
            consistent with the GRCh38 reference genome assembly.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11853562.31365.1,
                                           SRR14038192.2460855.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968189, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000615648.2/ ENSP00000484472.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC109322.16        193428-193430
            4-510               BP313273.1         1-507
            511-4576            AC109322.16        199077-203142
            4577-14213          AC234917.3         1-9637
            14214-15420         AL137725.1         1-1207
            15421-15432         AC234917.3         10845-10856
            15433-16005         AL137725.1         1229-1801
FEATURES             Location/Qualifiers
     source          1..16005
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.3"
     gene            1..16005
                     /gene="EPPK1"
                     /gene_synonym="EPIPL; EPIPL1"
                     /note="epiplakin 1"
                     /db_xref="GeneID:83481"
                     /db_xref="HGNC:HGNC:15577"
                     /db_xref="MIM:607553"
     exon            1..30
                     /gene="EPPK1"
                     /gene_synonym="EPIPL; EPIPL1"
                     /inference="alignment:Splign:2.1.0"
     exon            31..16005
                     /gene="EPPK1"
                     /gene_synonym="EPIPL; EPIPL1"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..15342
                     /gene="EPPK1"
                     /gene_synonym="EPIPL; EPIPL1"
                     /note="epidermal autoantigen 450K; 450 kDa epidermal
                     antigen"
                     /codon_start=1
                     /product="epiplakin"
                     /protein_id="NP_112598.3"
                     /db_xref="CCDS:CCDS75800.1"
                     /db_xref="GeneID:83481"
                     /db_xref="HGNC:HGNC:15577"
                     /db_xref="MIM:607553"
                     /translation="MSGHTLPPLPVPGTNSTEQASVPRAMAATLGAGTPPRPQARSIA
                     GVYVEASGQAQSVYAAMEQGLLPAGLGQALLEAQAATGGLVDLARGQLLPVSKALQQG
                     LVGLELKEKLLAAERATTGYPDPYGGEKLALFQAIGKEVVDRALGQSWLEVQLATGGL
                     VDPAQGVLVAPEPACHQGLLDRETWHKLSELEPGTGDLRFLDPNTLERLTYHQLLERC
                     VRAPGSGLALLPLKITFRSMGGAVSAAELLEVGILDEQAVQGLREGRLAAVDVSARAE
                     VRRYLEGTGSVAGVVLLPEGHKKSFFQAATEHLLPMGTALPLLEAQAATHTLVDPITG
                     QRLWVDEAVRAGLVSPELHEQLLVAEQAVTGHHDPFSGSQIPLFQAMKKGLVDRPLAL
                     RLLDAQLATGGLVCPARRLRLPLEAALRCGCLDEDTQRQLSQAGSFSDGTHGGLRYEQ
                     LLALCVTDPETGLAFLPLSGGPRGGEPQGPPFIKYSTRQALSTATATVSVGKFRGRPV
                     SLWELLFSEAISSEQRAMLAQQYQEGTLSVEKLAAKLSATLEQAAATARVTFSGLRDT
                     VTPGELLKAEIIDQDLYERLEHGQATAKDVGSLASVQRYLQGTGCIAGLLLPGSQERL
                     SIYEARCKGLLRPGTALILLEAQAATGFIIDPKANKGHSVEEALRAAVIGPDVFAKLL
                     SAERAVTGYTDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPV
                     DVAYRRGYFDQMLNLILLDPSDDTKGFFDPNTHENLTYLQLLERCVRDPETGLYLLPL
                     SSTQSPLVDSATQQAFQNLLLSVKYGRFQGQRVSAWELINSEYFSEGRRRQLLRRYRQ
                     REVTLGQVAKLLEAETQRQADIMLPALRSRVTVHQLLEAGIIDQQLLDQVLAGTISPE
                     ALLLMDGVRRYLCGLGAVGGVRLLPSGQRLSLYQAMRQKLLGPRVALALLEAQAATGT
                     IMDPHSPESLSVDEAVRRGVVGPELYGRLKRAEGAIAGFRDPFSGKQVSVFQAMKKGL
                     IPWEQAARLLEAQVATGGIIDPTSHHHLPMPVAIQRGYVDQEMETALSSSSETFPTPD
                     GQGRTSYAQLLEECPRDETSGLHLLPLPESAPALPTEEQVQRSLQAVPGAKDGTSLWD
                     LLSSCHFTEEQRRGLLEDVQEGRTTVPQLLASVQRWVQETKLLAQARVMVPGPRGEVP
                     AVWLLDAGIITQETLEALAQGTQSPAQVAEQPAVKACLWGTGCVAGVLLQPSGAKASI
                     AQAVRDGLLPTGLGQRLLEAQVASGFLVDPLNNQRLSVEDAVKVGLVGRELSEQLGQA
                     ERAAAGYPDPYSRASLSLWQAMEKGLVPQNEGLPLLQVQLATGGVVDPVHGVHLPQAA
                     ACRLGLLDTQTSQVLTAVDKDNKFFFDPSARDQVTYQQLRERCVCDSETGLLLLPLPS
                     DTVLEVDDHTAVALRAMKVPVSTGRFKGCSVSLWDLLLSEYVGADKRRELVALCRSGR
                     AAALRQVVSAVTTLVEAAERQPLQATFRGLRKQVSARDLFRAQLISRKTLDELSQGTT
                     TVKEVAEMDSVKRSLEGGNFIAGVLIQGTQERMSIPEALRRHILRPGTALVLLEAQAA
                     TGFIIDPVENRKLTVEEAFKAGMFGKETYVKLLSAERAVTGYTDPYTGQQISLFQAMQ
                     KDLIVREHGIRLLEAQIATGGIIDPVHSHRVPVDVAYRCGYFDEEMNRILADPSDDTK
                     GFFDPNTHENLTYLQLLERCVEDPETGLYLLQIIKKGENYVYINEATRHVLQSRTAKM
                     RVGRFADQVVSFWDLLSSPYFTEDRKRELIQEYGAQSGGLEKLLEIITTTIEETETQN
                     QGIKVAAIRGEVTAADLFNSRVIDQKTLHTLRVGRTGGQALSTLECVKPYLEGSGCIA
                     GVTVPSTREVMSLHEASRKELIPAAFATWLLEAQAATGFLLDPCTRQKLSVDEAVDVG
                     LVNEELRERLLKAERAATGYRDPATGDTIPLFQAMQKQLIEKAEALRLLEVQVATGGV
                     IDPQHHHRLPLETAYRRGCLHKDIYALISDQKHMRKRFVDPNTQEKVSYRELQERCRP
                     QEDTGWLLFPVNKAARDSEHIDDETRRALEAEQVEITVGRFRGQKPTLWALLNSEYVT
                     EEKKLQLVRMYRTHTRRALQTVAQLILELIEKQETSNKHLWFQGIRRQITASELLSSA
                     IITEEMLQDLETGRSTTQELMEDDRVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQA
                     MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERA
                     VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR
                     RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGS
                     AVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTL
                     TVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWD
                     VLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPR
                     EPGPAGRGDGDSGRSQREGQGEGETQEAAAAAAAAAARRQEQTLRDATMEVQRGQFQG
                     RPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRG
                     LRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAK
                     DQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVV
                     GGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVID
                     PVHSHRVPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQLLRRCVPDP
                     DTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWELLFYREVSED
                     RRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPREALRAATMEV
                     KVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAP
                     GARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAAARRQEQTLRDATM
                     EVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLVAVLTRVIEETEE
                     RLSKVSFRGLRCQVSASELHTSGILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSC
                     IAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSV
                     EEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEA
                     QIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYVQ
                     LLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSGALQGQSVSVWEL
                     LFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAEAEAGSPRPDPRE
                     ALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGTLDLPALTRRLTA
                     IIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEGETQEAAAATAAA
                     RRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQHAAGALGLPDLV
                     AVLTRVIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLAQGTKTLQEVTEM
                     DSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQAMWKGVLRPGTALVLLEAQAATGF
                     VIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQQISLFQAMQKDL
                     IVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFF
                     DPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRCALRDARVTPGSG
                     ALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTSLLAQAQAQARAE
                     AEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSRAAREELLAEFGSGT
                     LDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGDGDSGRSQREGQGEG
                     ETQEAAAATAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYLSEARRDELLAQ
                     HAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSGILGPETLRDLA
                     QGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGHQEKMSIYQAMWKGVLRPGTA
                     LVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERAVTGYTDPYTGQ
                     QISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRV
                     LAHPSDDTKGFFDPNTHENLTYVQLLRRCVPDPDTGLYMLQLAGRGSAVHQLSEELRC
                     ALRDARVMPGSGALQGQSVSVWELLFYREVSEDRRQDLLSRYRAGTLTVEELGATLTS
                     LLAQAQAQARAEAEAEAGSPRPDPREALRAATMEVKVGRLRGRAVPVWDVLASGYVSG
                     AAREELLAEFGSGTLDLPALTRRLTAIIEEAEEAPGARPQLQDAWRGPREPGPAGRGD
                     GDSGRSQREGQGEGETQEAAAAARRQEQTLRDATMEVQRGQFQGRPVSVWDVLFSSYL
                     SEAHRDELLAQHAAGALGLPDLVAVLTRVIEETEERLSKVSFRGLRRQVSASELHTSG
                     ILGPETLRDLAQGTKTLQEVTEMDSVKRYLEGTSCIAGVLVPAKDQPGRQEKMSIYQA
                     MWKGVLRPGTALVLLEAQAATGFVIDPVRNLRLSVEEAVAAGVVGGEIQEKLLSAERA
                     VTGYTDPYTGQQISLFQAMQKDLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYR
                     RGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLQRATLDPETGLLFLSLSLQ"
     regulatory      15716..15721
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EPPK1"
                     /gene_synonym="EPIPL; EPIPL1"
                     /note="hexamer: ATTACA"
     polyA_site      15738
                     /gene="EPPK1"
                     /gene_synonym="EPIPL; EPIPL1"
                     /note="major polyA site"
     regulatory      15988..15993
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EPPK1"
                     /gene_synonym="EPIPL; EPIPL1"
                     /note="hexamer: AGTAAA"
     polyA_site      16005
                     /gene="EPPK1"
                     /gene_synonym="EPIPL; EPIPL1"
ORIGIN      
        1 gacactgcgg accgagcggc gagcgggcag gacagaggtg gacctcagca ggctctgcat
       61 aaccagccgt gtgtgatgag tggccacacc ttgcctcctc ttcccgtccc aggcaccaac
      121 agcacagagc aggccagtgt acccagagcc atggcagcca cgctgggagc cggcacgccc
      181 cccaggcccc aggccaggag catagctggg gtgtatgtgg aggcctcggg ccaggcccag
      241 agtgtctacg ccgccatgga gcagggcctc ctgcctgctg ggctcgggca ggctctgcta
      301 gaggcccagg cagccactgg gggcctggtg gacctcgccc ggggccagct gctccctgtg
      361 tccaaggccc tgcagcaggg tctggtgggg ctggagctga aggagaagct gctggccgct
      421 gagcgtgcca ctacgggcta tcctgacccc tacggcggtg agaagctggc cctctttcag
      481 gccatcggga aggaggttgt ggacagggcc ctggggcaga gctggctgga ggtccaactg
      541 gccactgggg gcctggtgga ccccgcccag ggagtgctcg tggcccctga gccagcctgc
      601 caccagggcc tcctggaccg ggagacatgg cacaagctgt cagagcttga gcctggcaca
      661 ggtgacctgc gcttcctcga ccccaacacg ctggagcggc tgacatacca ccagctgctg
      721 gaaaggtgtg tgcgtgcccc cggctcgggg ctagccttgc tgcccctcaa gatcaccttc
      781 cgctccatgg gcggggcggt gagtgcagct gagctgctgg aggtgggcat cctggacgag
      841 caggctgtgc agggtctgcg ggagggcagg ctggccgcag tggacgtgag tgcacgtgcc
      901 gaggtgcggc gctacctgga gggtaccggc agcgtggccg gggttgtcct gctgcccgaa
      961 ggccacaaga agagcttttt ccaggctgcc accgagcacc tgctcccaat gggcaccgcg
     1021 ctgccactcc tagaggccca ggctgccacc cacaccctgg tggaccccat cacaggccag
     1081 cggctgtggg tagacgaggc agtcagggcg ggcctggtca gcccagagct ccatgagcag
     1141 ctcctggtgg ccgagcaggc cgtgacaggg caccacgacc ccttcagtgg ctcccaaatc
     1201 ccccttttcc aggccatgaa gaaggggcta gtggacaggc cactggcact gcggctcttg
     1261 gatgcccagc tggccacagg cgggctggtc tgtccagcac gcaggctccg gctgcccctg
     1321 gaggccgccc tgcgctgcgg ctgcctggat gaagacactc agcggcagct ctcgcaggct
     1381 ggcagcttct cagacggcac gcacggcggc ctgcgctatg aacagctgct ggccctctgt
     1441 gtcaccgacc cagagaccgg gcttgccttc ctgccactct cagggggacc ccggggaggg
     1501 gagccccagg gacccccatt catcaagtac agcactcggc aggccctgag cacggccaca
     1561 gccaccgtct ctgtggggaa gttccggggc cggcccgtgt ccctctggga gctgctcttc
     1621 tctgaggcca tctcctcaga gcagagggcg atgctggccc agcagtacca ggaagggacc
     1681 ctctccgtgg agaagctggc cgctaagctg agcgccaccc tcgagcaggc tgcagccact
     1741 gccagggtca ccttttctgg gctgagggac accgtgacac caggagagct gctgaaagcc
     1801 gagatcatcg accaggacct gtacgagcgg ctggagcatg gacaggccac agccaaggat
     1861 gtgggcagcc tggcctcggt gcagaggtac ctgcagggta cgggctgcat tgctggcctg
     1921 ctgctccctg gctcccagga acgcctgagc atctatgagg cccgatgcaa ggggctcctc
     1981 cggcccggca ctgccctcat ccttctggag gcacaagctg ccacaggctt catcatcgac
     2041 ccaaaagcaa acaaggggca ctccgttgag gaggcactga gggctgctgt cattgggcct
     2101 gatgtgttcg cgaagctgct gtcggctgag cgcgctgtca ctggctacac tgacccctac
     2161 accgggcagc agatctccct cttccaggcc atgcagaagg gcctcatcgt ccgggagcac
     2221 ggcatccgcc tgctggaggc ccagatcgcc acgggcggcg tcatcgaccc cgtgcacagc
     2281 caccgcgtgc ccgtggacgt ggcctaccgg cgcggctact tcgatcagat gctgaacttg
     2341 atcctgttgg acccttctga cgacaccaag ggcttcttcg accccaacac gcacgagaac
     2401 ctcacgtacc tgcagcttct ggagcgctgt gtgcgtgacc ccgagacggg cctgtacctc
     2461 ctgccactca gcagcacgca gtccccgctg gtggacagtg ccacccagca ggccttccag
     2521 aacctgctgc tctccgtgaa gtatggacgg tttcaggggc agagggtctc cgcgtgggag
     2581 ctgatcaact ctgagtactt cagcgagggc cgcaggaggc agctgctgcg tcgctaccgg
     2641 cagcgcgagg tcacgctggg gcaggtggca aagctgctgg aggcggagac gcagagacag
     2701 gcggacatca tgctgcccgc actgcggagc cgggtcaccg tccaccagct cctggaggcc
     2761 ggtatcattg accagcagct gttggaccaa gtgctggccg ggacaatcag cccggaggcc
     2821 ctcctactca tggacggcgt ccgcaggtac ctgtgcggcc tgggagctgt gggcggtgtg
     2881 cggctgctgc cctctggcca gcggctcagc ctctaccagg ccatgaggca gaagctgctg
     2941 gggcccaggg tggccctggc cctgctggag gcccaggcgg ccaccggaac catcatggac
     3001 cctcacagcc cagagagcct ctcggtggat gaggccgtgc gcaggggtgt ggtggggccg
     3061 gagctgtatg gcaggctgaa gcgggctgag ggtgccattg ctggcttcag agaccccttc
     3121 tctgggaagc aggtgtctgt gttccaggcc atgaagaaag gtctcatccc ttgggagcaa
     3181 gctgcccgcc tcctggaggc tcaagtggcc acaggaggga tcattgaccc caccagccac
     3241 caccacctcc ccatgccagt ggccattcag cgtggctatg ttgaccagga gatggagaca
     3301 gccttgtcca gctcctccga aaccttcccc acaccggacg gccaggggcg cacgagctat
     3361 gcccagctcc tggaggagtg ccccagggat gagacttctg gccttcacct cctgcccctg
     3421 ccagaaagtg ctcctgccct ccccaccgag gagcaggtcc agaggagcct gcaggccgtg
     3481 ccgggggcca aggatggcac atccctctgg gacctgctca gctcctgcca cttcaccgag
     3541 gagcaacgga ggggcctgct ggaggacgtg caggagggga ggaccactgt gccacagctg
     3601 ctagcctctg tgcagaggtg ggtacaggag accaagctcc tggcccaggc ccgcgtcatg
     3661 gtgcccggcc cacggggtga ggtacccgct gtctggctgc tggatgctgg catcatcacc
     3721 caggagaccc ttgaggccct ggctcagggc acgcagtcgc ccgcccaggt cgccgagcag
     3781 ccggcggtga aggcctgcct gtggggcaca ggctgcgtgg ccggtgtgct gctacagccc
     3841 tctggggcca aggccagcat cgcccaggcc gtgagggatg gcctcctgcc cacaggcctg
     3901 ggccagaggc tgctggaagc ccaggtggca tctggcttcc ttgttgaccc cctgaacaac
     3961 cagagactgt cagtggagga cgcggttaag gtcggcctgg tgggcaggga gctgagtgag
     4021 cagctcgggc aggccgagag ggcggcggcc gggtacccag atccctactc tagggcctcc
     4081 ctctctctgt ggcaggccat ggagaagggg ctcgtgccac agaacgaggg cttgcccctc
     4141 ctgcaggtgc agctggccac agggggtgtg gtggaccctg tccacggggt gcacctgccc
     4201 caggcggcag cctgcagact cggccttctg gacacacaga cgagccaggt gctgactgca
     4261 gttgacaagg acaacaagtt cttctttgac cccagtgcgc gggaccaggt gacctaccag
     4321 cagctcaggg agcgctgcgt gtgcgactcc gagaccggat tgttgctgtt gccactgccc
     4381 tcagacacag tgcttgaggt ggacgaccac accgcggtgg ctctgagggc catgaaggtg
     4441 cccgtcagca cagggaggtt taaggggtgt agcgtgtcac tctgggacct gctgctctcc
     4501 gaatacgttg gcgctgacaa gcggcgggag ctggtggcac tctgtcggtc tgggagggct
     4561 gcggccctgc ggcaggtggt cagcgcagtc accaccctgg tcgaggctgc agagaggcag
     4621 cccctgcagg ccaccttcag agggctccgg aagcaggtgt cagccaggga cctgttcagg
     4681 gcgcagctga tcagcaggaa gacgctggac gagctgagcc aggggacaac gactgtgaag
     4741 gaggtggcgg agatggacag cgtgaagcgg tccctggagg gaggcaactt cattgccggg
     4801 gtccttatcc agggcaccca ggagaggatg agcatcccag aggccctgag gaggcacatc
     4861 ctgcggcctg gcacagccct ggtgctgctg gaggcacagg cagctaccgg cttcatcatc
     4921 gaccccgtgg agaaccggaa gctgaccgtg gaggaggcgt tcaaagcagg aatgttcggg
     4981 aaagaaacct acgtgaagct gctgtcggcc gagcgcgccg tcaccggcta caccgacccc
     5041 tataccgggc agcagatctc cctcttccag gccatgcaga aggacctcat cgtccgggag
     5101 cacggcatcc gcctgctgga ggcccagatc gccacgggcg gcatcatcga ccccgtgcac
     5161 agccaccgcg tgcccgtgga cgtggcctac cgctgcggct acttcgacga ggagatgaac
     5221 cgcatcctgg cggaccccag cgacgacacc aagggcttct tcgaccccaa cacgcacgag
     5281 aacctcacgt acctgcagct tctggagcgc tgtgtggagg accccgagac gggcctgtac
     5341 ctgctacaaa tcataaagaa aggagaaaac tacgtgtaca tcaatgaggc cacgagacac
     5401 gtgttgcaat ccagaactgc aaaaatgcgc gtggggaggt ttgctgacca ggtggtctct
     5461 ttctgggacc tgctgtcctc tccatacttc acagaggaca ggaagcggga gctcatccag
     5521 gagtatggag cccagagtgg gggcctggag aaattgctgg aaatcatcac cacgacaatt
     5581 gaagaaacag agacgcaaaa ccaaggcatc aaagtggcgg ccatcagagg ggaggtgaca
     5641 gctgcagacc tgttcaactc cagggtcatc gatcagaaga ccctgcacac acttcgtgtg
     5701 gggaggactg ggggacaggc actcagcacg ctggagtgtg tgaagcccta tctggaaggc
     5761 agcggctgca ttgcgggggt cacggtgccc tccaccaggg aggtcatgag cctccatgag
     5821 gccagcagga aggagctcat ccctgcagca tttgcgactt ggctgctgga ggcgcaggcc
     5881 gccaccgggt tcctcctgga cccctgcacc cgccagaagc tctctgtgga tgaggctgtg
     5941 gatgtgggcc tggtgaacga ggagctgcgg gagaggctcc tgaaggctga aagagctgcc
     6001 acgggctaca gggatccggc cacaggagac acgatcccgc tgttccaggc catgcagaag
     6061 cagctcatcg agaaggcgga ggcactgagg ctgctggagg tgcaggtggc cacggggggt
     6121 gtcatcgacc cacagcacca ccaccggctc ccactggaaa cagcctacag acggggctgt
     6181 ctgcacaagg acatctatgc gctcatttcc gaccagaagc acatgaggaa acggtttgtg
     6241 gacccgaaca cgcaagagaa ggtctcgtac cgagagctgc aggagaggtg ccgcccacaa
     6301 gaggacacgg gctggctgct gttcccagtg aacaaggctg cacgggactc cgagcacatc
     6361 gatgacgaga cgagaagggc cctggaggca gagcaagtgg aaatcacagt gggaaggttc
     6421 agaggccaga aaccaacact gtgggcacta ctgaattccg aatacgtgac agaggagaag
     6481 aagctccagc tggtgaggat gtatagaaca cacaccagac gggcactgca gacggtagcg
     6541 cagctcatct tagagttgat cgagaagcag gaaaccagca acaaacacct gtggttccaa
     6601 ggaattagac gacagatcac agcttctgaa ctcctcagct cagccataat cacggaggaa
     6661 atgctccagg acctggaaac gggacggagc acgacgcaag agctcatgga ggacgaccgc
     6721 gtcaagcgct acctggaggg caccagctgc atcgcgggcg tcctggtgcc cgccaaggac
     6781 cagcccggcc gccaggagaa gatgagcatc taccaggcca tgtggaaggg cgtgctgcgg
     6841 cccggcacgg ccctggtgct gctggaggcg caggcggcca ccggcttcgt catcgacccc
     6901 gtgcgcaacc tgaggctgtc ggtggaggag gccgtggccg cgggcgtggt gggcggcgag
     6961 atccaggaga agctgctgtc ggccgagcgc gccgtcaccg gctacaccga cccctacacc
     7021 gggcagcaga tctccctctt ccaggccatg cagaaggacc tcatcgtccg ggagcacggc
     7081 atccgcctgc tggaggccca gatcgccacg ggcggcgtca tcgaccccgt gcacagccac
     7141 cgcgtgcccg tggacgtggc ctaccggcgc ggctacttcg acgaggagat gaaccgtgtc
     7201 ctggccgacc ccagcgacga caccaagggc ttcttcgacc ccaacacgca cgagaacctc
     7261 acgtacgtgc agctgctgcg ccgctgcgtg cccgacccgg acaccgggct ctacatgctg
     7321 cagctggcag gccggggctc cgccgtgcac cagctgagcg aggagctgcg ctgtgccctg
     7381 cgcgacgccc gcgtgacgcc aggctcgggc gccctccagg gccagagcgt ctccgtctgg
     7441 gagctcctct tctaccgcga ggtgtccgag gaccggcgcc aggacctgct gagcagatac
     7501 cgggcgggca cgctgaccgt ggaggagctg ggcgccaccc tcacctcgct gctggcccag
     7561 gcccaggccc aggcccgggc cgaggccgag gccgggagcc cgcgcccaga cccccgggag
     7621 gccctgcgtg cggccaccat ggaggtcaag gtgggccgcc tccgggggcg cgcggtgccc
     7681 gtgtgggacg tgctggcgtc cggctacgtg agcagggccg cccgggagga gctgctggcc
     7741 gagtttggct cggggaccct ggacttgccc gcgctgaccc gccggctgac cgccatcatc
     7801 gaggaggccg aggaggcccc cggggcccgg ccgcagctcc aggacgcctg gcgcggcccg
     7861 cgggagccag ggccagccgg gcgaggggac ggcgactcgg ggcgctccca gcgagagggc
     7921 cagggggagg gcgagaccca ggaggccgcc gccgccgccg ccgccgccgc cgcccgccgc
     7981 caggagcaga ccctgcgtga tgccaccatg gaggtgcagc gcgggcagtt ccaggggcgg
     8041 ccggtctccg tgtgggacgt cctcttctcc tcgtacctga gcgaggcccg ccgagacgag
     8101 ctcctggccc agcacgcggc cggcgccctg ggcctgcccg acctcgtcgc cgtcctcacc
     8161 cgggtcatcg aggagaccga ggagcggctc agcaaggtgt ccttccgcgg cctgaggcgc
     8221 caggtgtccg cctccgagct gcacacgtcc gggatcctgg gccccgagac cctgcgggac
     8281 ctggcccagg gcactaagac gctgcaggag gtgacggaga tggactcggt caagcgctac
     8341 ctggagggca ccagctgcat cgcgggcgtc ctggtgcccg ccaaggacca gcccggccgc
     8401 caggagaaga tgagcatcta ccaggccatg tggaagggcg tgctgcggcc cggcacggcc
     8461 ctggtgctgc tggaggcgca ggcggccacc ggcttcgtca tcgaccccgt gcgcaacctg
     8521 aggctgtcgg tggaggaggc cgtggccgcg ggcgtggtgg gcggcgagat ccaggagaag
     8581 ctgctgtcgg ccgagcgcgc cgtcaccggc tacaccgacc cctacaccgg gcagcagatc
     8641 tccctcttcc aggccatgca gaaggacctc atcgtccggg agcacggcat ccgcctgctg
     8701 gaggcccaga tcgccacggg cggcgtcatc gaccccgtgc acagccaccg cgtgcccgtg
     8761 gacgtggcct accagcgcgg ctacttcgac gaggagatga accgtgtcct ggccgacccc
     8821 agcgacgaca ccaagggctt cttcgacccc aacacgcacg agaacctcac gtacgtgcag
     8881 ctgctgcgcc gctgcgtgcc cgacccggac accgggctct acatgctgca gctggcaggc
     8941 cggggctccg ccgtgcacca gctgagcgag gagctgcgct gtgccctgcg cgacgcccgc
     9001 gtgacgccag gctcgggcgc cctccagggc cagagcgtct ccgtctggga gctcctcttc
     9061 taccgcgagg tgtccgagga ccggcgccag gacctgctga gcagataccg ggcgggcacg
     9121 ctgaccgtgg aagagctggg cgccaccctc acctcgctgc tggcccaggc ccaggcccag
     9181 gcccgggccg aggccgaggc cgggagcccg cgcccagacc cccgggaggc cctgcgtgcg
     9241 gccaccatgg aggtcaaggt gggccgcctc cgggggcgcg cggtgcccgt gtgggacgtg
     9301 ctggcgtccg gctacgtgag cagggccgcc cgggaggagc tgctggccga gtttggctcg
     9361 gggaccctgg acttgcccgc gctgacccgc cggctgaccg ccatcatcga ggaggccgag
     9421 gaggcccccg gggcccggcc gcagctccag gacgcctggc gcggcccgcg ggagccaggg
     9481 ccagccgggc gaggggacgg cgactcgggg cgctcccagc gagagggcca gggggagggc
     9541 gagacccagg aggccgccgc cgccgcccgc cgccaggagc agaccctgcg tgatgccacc
     9601 atggaggtgc agcgcgggca gttccagggg cggccggtct ccgtgtggga cgtcctcttc
     9661 tcctcgtacc tgagcgaggc ccgccgagac gagctcctgg cccagcacgc ggccggcgcc
     9721 ctgggcctgc ccgacctcgt cgccgtcctc acccgggtca tcgaggagac ggaggagcgg
     9781 ctcagcaagg tgtccttccg cggcctgagg tgccaggtgt ccgcctccga gctgcacacg
     9841 tccgggatcc tgggccccga gaccctgcgg gacctggccc agggcactaa gacgctgcag
     9901 gaggtgacgg agatggactc ggtcaagcgc tacctggagg gcaccagctg catcgcgggc
     9961 gtcctggtgc ccgccaagga ccagcccggc cgccaggaga agatgagcat ctaccaggcc
    10021 atgtggaagg gcgtgctgcg gcccggcacg gccctggtgc tgctggaggc gcaggcggcc
    10081 accggcttcg tcatcgaccc cgtgcgcaac ctgaggctgt cggtggagga ggccgtggcc
    10141 gcgggcgtgg tgggcggcga gatccaggag aagctgctgt cggccgagcg cgccgtcacc
    10201 ggctacaccg acccctacac cgggcagcag atctccctct tccaggccat gcagaaggac
    10261 ctcatcgtcc gggagcacgg catccgcctg ctggaggccc agatcgccac gggcggcgtc
    10321 atcgaccccg tgcacagcca ccgcgtgccc gtggacgtgg cctaccggcg cggctacttc
    10381 gacgaggaga tgaaccgtgt cctggccgac cccagcgacg acaccaaggg cttcttcgac
    10441 cccaacacgc acgagaacct cacgtacgtg cagctgctgc gccgctgcgt gcccgacccg
    10501 gacaccgggc tctacatgct gcagctggca ggccggggct ccgccgtgca ccagctgagc
    10561 gaggagctgc gctgtgccct gcgcgacgcc cgcgtgacgc caggctcggg cgccctccag
    10621 ggccagagcg tctccgtctg ggagctcctc ttctaccgcg aggtgtccga ggaccggcgc
    10681 caggacctgc tgagcagata ccgggcgggc acgctgaccg tggaggagct gggcgccacc
    10741 ctcacctcgc tgctggccca ggcccaggcc caggcccggg ccgaggccga ggccgggagc
    10801 ccgcgcccag acccccggga ggccctgcgt gcggccacca tggaggtcaa ggtgggccgc
    10861 ctccgggggc gcgcggtgcc cgtgtgggac gtgctggcgt ccggctacgt gagcagggcc
    10921 gcccgggagg agctgctggc cgagtttggc tcggggaccc tggacttgcc cgcgctgacc
    10981 cgccggctga ccgccatcat cgaggaggcc gaggaggccc ccggggcccg gccgcagctc
    11041 caggacgcct ggcgcggccc gcgggagcca gggccagccg ggcgagggga cggcgactcg
    11101 gggcgctccc agcgagaggg ccagggggag ggcgagaccc aggaggccgc cgccgccacc
    11161 gccgccgccc gccgccagga gcagaccctg cgtgatgcca ccatggaggt gcagcgcggg
    11221 cagttccagg ggcggccggt ctccgtgtgg gacgtcctct tctcctcgta cctgagcgag
    11281 gcccgccgag acgagctcct ggcccagcac gcggccggcg ccctgggcct gcccgacctc
    11341 gtcgccgtcc tcacccgggt catcgaggag acggaggagc ggctcagcaa ggtgtccttc
    11401 cgcggcctga ggcgccaggt gtccgcctcc gagctgcaca cgtccgggat cctgggcccc
    11461 gagaccctgc gggacctggc ccagggcact aagacgctgc aggaggtgac ggagatggac
    11521 tcggtcaagc gctacctgga gggcaccagc tgcatcgcgg gcgtcctggt gcccgccaag
    11581 gaccagcccg gccgccagga gaagatgagc atctaccagg ccatgtggaa gggcgtgctg
    11641 cggcccggca cggccctggt gctgctggag gcgcaggcgg ccaccggctt cgtcatcgac
    11701 cccgtgcgca acctgaggct gtcggtggag gaggccgtgg ccgcgggcgt ggtgggcggc
    11761 gagatccagg agaagctgct gtcggccgag cgcgccgtca ccggctacac cgacccctac
    11821 accgggcagc agatctccct cttccaggcc atgcagaagg acctcatcgt ccgggagcac
    11881 ggcatccgcc tgctggaggc ccagatcgcc acgggcggcg tcatcgaccc cgtgcacagc
    11941 caccgcgtgc ccgtggacgt ggcctaccgg cgcggctact tcgacgagga gatgaaccgt
    12001 gtcctggccg accccagcga cgacaccaag ggcttcttcg accccaacac gcacgagaac
    12061 ctcacgtacg tgcagctgct gcgccgctgc gtgcccgacc cggacaccgg gctctacatg
    12121 ctgcagctgg caggccgggg ctccgccgtg caccagctga gcgaggagct gcgctgtgcc
    12181 ctgcgcgacg cccgcgtgac gccaggctcg ggcgccctcc agggccagag cgtctccgtc
    12241 tgggagctcc tcttctaccg cgaggtgtcc gaggaccggc gccaggacct gctgagcaga
    12301 taccgggcgg gcacgctgac cgtggaggag ctgggcgcca ccctcacctc gctgctggcc
    12361 caggcccagg cccaggcccg ggccgaggcc gaggccggga gcccgcgccc agacccccgg
    12421 gaggccctgc gtgcggccac catggaggtc aaggtgggcc gcctccgggg gcgcgcggtg
    12481 cccgtgtggg acgtgctggc gtccggctac gtgagcaggg ccgcccggga ggagctgctg
    12541 gccgagtttg gctcggggac cctggacttg cccgcgctga cccgccggct gaccgccatc
    12601 atcgaggagg ccgaggaggc ccccggggcc cggccgcagc tccaggacgc ctggcgcggc
    12661 ccgcgggagc cagggccagc cgggcgaggg gacggcgact cggggcgctc ccagcgagag
    12721 ggccaggggg agggcgagac ccaggaggcc gccgccgcca ccgccgccgc ccgccgccag
    12781 gagcagaccc tgcgtgatgc caccatggag gtgcagcgcg ggcagttcca ggggcggccg
    12841 gtctccgtgt gggacgtcct cttctcctcg tacctgagcg aggcccgccg agacgagctc
    12901 ctggcccagc acgcggccgg cgccctgggc ctgcccgacc tcgtcgccgt cctcacccgg
    12961 gtcatcgagg agacggagga gcggctcagc aaggtgtcct tccgcggcct gaggcgccag
    13021 gtgtccgcct ccgagctgca cacgtccggg atcctgggcc ccgagaccct gcgggacctg
    13081 gcccagggca ctaagacgct gcaggaggtg acggagatgg actcggtcaa gcgctacctg
    13141 gagggcacca gctgcatcgc gggcgtcctg gtgcccgcca aggaccagcc cggccaccag
    13201 gagaagatga gcatctacca ggccatgtgg aagggcgtgc tgcggcccgg cacggccctg
    13261 gtgctgctgg aggcgcaggc ggccaccggc ttcgtcatcg accccgtgcg caacctgagg
    13321 ctgtcggtgg aggaggccgt ggccgcgggc gtggtgggcg gcgagatcca ggagaagctg
    13381 ctgtcggccg agcgcgccgt caccggctac accgacccct acaccgggca gcagatctcc
    13441 ctcttccagg ccatgcagaa ggacctcatc gtccgggagc acggcatccg cctgctggag
    13501 gcccagatcg ccacgggcgg cgtcatcgac cccgtgcaca gccaccgcgt gcccgtggac
    13561 gtggcctacc ggcgcggcta cttcgacgag gagatgaacc gtgtcctggc ccaccccagc
    13621 gacgacacca agggcttctt cgaccccaac acgcacgaga acctcacgta cgtgcagctg
    13681 ctgcgccgct gcgtgcccga cccggacacc gggctctaca tgctgcagct ggcaggccgg
    13741 ggctccgccg tgcaccagct gagcgaggag ctgcgctgtg ccctgcgcga cgcccgcgtg
    13801 atgccaggct cgggcgccct ccagggccag agcgtctccg tctgggagct cctcttctac
    13861 cgcgaggtgt ccgaggaccg gcgccaggac ctgctgagca gataccgggc gggcacgctg
    13921 accgtggagg agctgggcgc caccctcacc tcgctgctgg cccaggccca ggcccaggcc
    13981 cgggccgagg ccgaggccga ggccgggagc ccgcgcccag acccccggga ggccctgcgt
    14041 gcggccacca tggaggtcaa ggtgggccgc ctccgggggc gcgcggtgcc cgtgtgggac
    14101 gtgctggcgt ccggctacgt gagcggggcc gcccgggagg agctgctggc cgagtttggc
    14161 tcggggaccc tggacttgcc cgcgctgacc cgccggctga ccgccatcat cgaggaggcc
    14221 gaggaggccc ccggggcccg gccgcagctc caggacgcct ggcgcggccc gcgggagcca
    14281 gggccagccg ggcgagggga cggcgactcg gggcgctccc agcgagaggg ccagggggag
    14341 ggcgagaccc aggaggccgc cgccgccgcc cgccgccagg agcagaccct gcgtgatgcc
    14401 accatggagg tgcagcgcgg gcagttccag gggcggccgg tctccgtgtg ggacgtcctc
    14461 ttctcctcgt acctgagcga ggcccaccga gacgagctcc tggcccagca cgcggccggc
    14521 gccctgggcc tgcccgacct cgtcgccgtc ctcacccggg tcatcgagga gacggaggag
    14581 cggctcagca aggtgtcctt ccgcggcctg aggcgccagg tgtccgcctc cgagctgcac
    14641 acgtccggga tcctgggccc cgagaccctg cgggacctgg cccagggcac taagacgctg
    14701 caggaggtga cggagatgga ctcggtcaag cgctacctgg agggcaccag ctgcatcgcg
    14761 ggcgtcctgg tgcccgccaa ggaccagccc ggccgccagg agaagatgag catctaccag
    14821 gccatgtgga agggcgtgct gcggcccggc acggccctgg tgctgctgga ggcgcaggcg
    14881 gccaccggct tcgtcatcga ccccgtgcgc aacctgaggc tgtcggtgga ggaggccgtg
    14941 gccgcgggcg tggtgggcgg cgagatccag gagaagctgc tgtcggccga gcgcgccgtc
    15001 accggctaca ccgaccccta caccgggcag cagatctccc tcttccaggc catgcagaag
    15061 gacctcatcg tccgggagca cggcatccgc ctgctggagg cccagatcgc cacgggcggc
    15121 gtcatcgacc ccgtgcacag ccaccgcgtg cccgtggacg tggcctaccg gcgcggctac
    15181 ttcgacgagg agatgaaccg cgtcctggcc gaccccagcg acgacaccaa gggcttcttc
    15241 gaccccaaca cgcacgagaa cctcacgtac ctgcagcttc tgcagagggc caccctggac
    15301 cctgagacgg ggctcctatt tctttctctc tctctacagt gactgggctt cctccgtgca
    15361 gttttctgca actctggaga agtggaggca tacttgtgtg tctgggttgt tttttttttt
    15421 tttttttttt ttgtcattct ttaattttgt tgttttaccc attcgttatc tgtggaaaac
    15481 gttttaagtt gtcatgtgac agaaactttt cctttgtcca tcgaggtgtt tcataagttt
    15541 tttggtgtgt tttctgggtc gtctatgtgt catatggttt tacttttctc tcctttttcg
    15601 ttttcagaac atttttctgt ctgttttgga ttcactgctt ccattttaca gaatgtcact
    15661 ctttagactc tcagtccatc atgccatcgg gtactcttgt tgcagtgtaa tttttattac
    15721 atgcggttat ttccctaacg atgtgctatt cacgttcatc ttcaaactca ttttccatca
    15781 gccagtgtct actatttagt gccctggctc tatttcggtc ctcctccccg ggctttccct
    15841 ggctgctgtg ctggccaaaa gcatgggctt tattctctcc attggctgct gctccacctt
    15901 agaggtgtga cctcactagc gttgactgag cgagtctgtt gtggagaaga actttttgta
    15961 gtaatttact aggaaaaatt ctgaacaagt aaaatatgaa ggaaa
//
