LOCUS       XM_047448975            6217 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens erythrocyte membrane protein band 4.1
            (EPB41), transcript variant X16, mRNA.
ACCESSION   XM_047448975
VERSION     XM_047448975.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6217
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..6217
                     /gene="EPB41"
                     /gene_synonym="4.1R; EL1; HE"
                     /note="erythrocyte membrane protein band 4.1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 44 ESTs, 1222 long SRA reads, 4 Proteins, and 97%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 41 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:2035"
                     /db_xref="HGNC:HGNC:3377"
                     /db_xref="MIM:130500"
     CDS             208..2988
                     /gene="EPB41"
                     /gene_synonym="4.1R; EL1; HE"
                     /codon_start=1
                     /product="protein 4.1 isoform X16"
                     /protein_id="XP_047304931.1"
                     /db_xref="GeneID:2035"
                     /db_xref="HGNC:HGNC:3377"
                     /db_xref="MIM:130500"
                     /translation="MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAE
                     GDNWCEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEV
                     ESDKEKGEGGQKEIEFGTSLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQE
                     ELREDPDFEIKEGEGLEECSKIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLD
                     DTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVR
                     GVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQ
                     SELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKK
                     LSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIK
                     IRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKSKFLALGSKFR
                     YSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTSAPAITQ
                     GQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDEPPEQAEPEPTEAWKDLDKSQEEI
                     KKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGSINGIRTE
                     EVAVVTKGPSTNPDSEWEGPKHSVVPSKSQMTTSSESLQSFAFGSLSISSKETEEKEE
                     GAAGYLDIKEMPRGPTGGCIGVEEQASALKFSVTPASCQLQPGVKKAESSEEHVTPGE
                     PPGKQNGSFLDFHVGNQFPTLIRSFQPPLVKTQTVTISDNANAVKSEIPTKDVPIVHT
                     ETKTITYEAAQTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTK
                     VVVHQETEIADE"
ORIGIN      
        1 agagggaagg cgggagggcg cgcgccaggg tcgctcgctc gctccctccc tccgctggtg
       61 cgtttagtca gtcagccagc agcagccggc gggcccgcga gccgcagagg gcccgagcct
      121 cggacgccgg cgcctcctcc tgccattgtt cgtcgggctg cagcagtggc gggcgcagga
      181 gcccggcccc ggagccaccg caacatcatg acaacagaga agagtttagt gactgaggcc
      241 gaaaattcac agcaccaaca gaaggaagag ggtgaggaag ccataaactc aggccaacaa
      301 gaacctcagc aggaggaatc ttgtcaaaca gcagctgaag gagataattg gtgtgaacag
      361 aagctgaaag cttctaatgg agacactcct acacatgaag acttgaccaa gaacaaggag
      421 cggacatcag aaagcagagg actttcacga ctattctcct cgtttctcaa aaggcccaaa
      481 tctcaggtgt ccgaggaaga aggcaaagaa gtagagtcag ataaagaaaa aggtgaagga
      541 ggtcagaaag agatagaatt tggaaccagt cttgatgaag agatcatttt aaaggcccca
      601 attgcagctc ctgaaccgga actcaaaaca gacccatctt tggatcttca ttcattaagc
      661 agtgcagaaa cacagcctgc tcaggaagaa ctcagagaag atccagattt tgaaattaag
      721 gaaggagaag gacttgaaga gtgctccaaa atagaagtaa aagaagaaag ccctcaatca
      781 aaagcagaaa cagaattaaa agcttcccaa aaaccaatca gaaaacacag gaacatgcac
      841 tgcaaggttt ctttgttgga tgacacagtt tatgaatgtg ttgtggagaa acatgctaag
      901 ggacaagatt tgcttaaacg agtatgtgag catctcaatc ttttggaaga agactatttt
      961 ggtctagcca tttgggataa cgcaacctct aagacatggc tggattccgc caaagaaata
     1021 aaaaagcagg ttcgtggtgt cccttggaat tttacattta atgtaaagtt ttatccacct
     1081 gacccagcac agttaacaga agacataaca agatattatt tatgtcttca gcttcggcag
     1141 gacatagttg caggacgtct gccctgttcc tttgcaacct tagcattatt aggttcttac
     1201 accatccagt ctgaactggg agactacgac ccagaactcc atggcgtgga ttatgttagt
     1261 gattttaaac tggccccgaa tcagaccaag gaacttgaag agaaggtcat ggaactgcat
     1321 aagtcataca ggtccatgac tccagctcag gctgacttgg agtttcttga gaatgccaaa
     1381 aagttgtcta tgtatggagt tgatcttcat aaagcaaagg acttggaagg agtagatatc
     1441 atcctaggtg tctgctctag tggccttctg gtttacaaag ataagctgag aattaaccgc
     1501 ttcccttggc ccaaagtgct gaagatttct tataaacgta gtagcttttt catcaagatt
     1561 cggcctggag agcaagagca gtatgaaagt accatcggat tcaaacttcc cagttaccga
     1621 gcagctaaga aattatggaa agtctgtgta gaacatcaca cgtttttcag attgacatct
     1681 acagacacca ttcccaaaag caaatttctt gcgctaggat ccaaatttcg atacagtggc
     1741 cggactcaag ctcagaccag gcaagctagt gctctaattg acaggcctgc cccacacttc
     1801 gagcgtacag caagtaaacg ggcgtcccgg agcctcgatg gagcagcagc tgtcgattcg
     1861 gcagaccgaa gtcctcggcc cacttctgca cctgccatta ctcagggtca ggttgcagaa
     1921 ggtggcgtcc tagatgcctc tgctaaaaaa acagtggtcc ctaaagcaca gaaggaaaca
     1981 gtgaaggctg aagtgaaaaa ggaagacgag ccacctgagc aagctgagcc agagcccaca
     2041 gaagcatgga aggatttaga caagagtcaa gaggagatca aaaaacatca tgccagcatc
     2101 agtgagctga aaaagaactt catggagtct gtaccagaac cacggcctag tgaatgggat
     2161 aaacgcttat ccactcactc acccttccga actcttaaca tcaatgggca aatccccaca
     2221 ggagaaggaa gtataaatgg cattcgcaca gaggaggtgg ctgtcgtgac aaaggggcca
     2281 tctactaacc ctgactctga atgggagggt cccaagcatt cggtagttcc tagtaaaagc
     2341 cagatgacca cctcgtcgga gtctctgcaa agctttgcct ttggctccct ctccataagc
     2401 agcaaggaga cagaagagaa ggaggagggg gcagctggct atcttgatat taaggagatg
     2461 ccaagaggcc caactggggg atgtatagga gtggaggaac aggccagtgc cttaaagttc
     2521 tcagtaacac cagcttcctg tcagctgcaa cctggtgtaa aaaaggcaga gagtagtgaa
     2581 gaacatgtta caccaggaga gccacctgga aaacaaaatg gatcatttct tgactttcat
     2641 gtgggtaacc agttccccac cctcattcga agtttccagc ctcccctggt gaagacacaa
     2701 actgtcacca tctcagataa tgccaatgct gtgaaaagtg aaatcccaac caaagacgtc
     2761 cctattgtcc acactgagac caagaccatc acttatgagg ctgcccagac tgtaaaaggt
     2821 gggatttcag agacacgtat tgaaaagaga attgtgatca caggagatgc tgatattgac
     2881 catgatcagg tccttgtaca agccatcaag gaggcaaagg agcagcaccc agacatgtca
     2941 gtgaccaagg tggtcgtcca ccaggagacc gagattgctg atgagtgagc tcaggaacta
     3001 acctacccca actctgccct tctcccatcc aagagaaacc agcaaaatga taaagaagct
     3061 aacctgccat agtcagactt cagactttca agattattct aaatcaccag aaaattaatt
     3121 tcagtttcta ttgggagttt ataccaagag attcttctag atctcattga tccttttgaa
     3181 gagctttttc tatattagga tatcagaatt gttcaacttt tcactctata gactgtttta
     3241 agagttttgg ggttttttta attgggtggt ttgtaacccc ttcagcctag cctctctgcc
     3301 catttatttc caaccccaac agacactgac agggtccatg gaattcttcg ggaaatcctc
     3361 caaggactct tgtcagctgt gttggaagcc aaagccagct tagtgggact tccgcgtctc
     3421 tccctagtct tatccccttt ggatgatggc agaaacttca tgaaccagcc ctttctcaga
     3481 gccagtgatg tgagtgtatc agaatgccag ggagggcacc agccctgatc cacagacctc
     3541 ggaaagatgc ccctgttcct ttgttgcggg tggttttggt aaggcagagc cctctgctga
     3601 gaatgtagta ttgtttttcc cctctccctc ctgctttctt tttggagctt ctttgggtca
     3661 aagacatgga agttgcttca gatatctgat actgtgaatg tttgaacata tccgtggcct
     3721 tcacctctcc agctaccctt ttacctcatc agaagcagtg gctcagctaa gtgctccccc
     3781 tagctcccat ctcaggagac caaatctcac agaaaaatag gcactttggg ccaaaagctc
     3841 taatggaaca tttttagtgg tgatttgggg aaggaaagtt aatgaggttt ttaaaataag
     3901 gttttctagt tttgagagtg tgcacttcac acaggggaat ggggttactt ctgtctgatc
     3961 ctgggccttt ctttcatccc aaatgacaag gaatgtggct cagagaaggg tttttctttt
     4021 ttgacctttc ttctctcaac aggaacctgc ctgaggacac ccttctagag caaggaattg
     4081 acttttagga gccgttctcc ccacaagaca ccacatgaca aggggtataa gccccagccc
     4141 tgctcattcc cactcaccag ctgaggtctg tcaggttttg aaggcttgat tttgtggtgg
     4201 gtttggggct tagttttcct ttttttcatt ttgatttttg aaagtgaaga tgatgcccta
     4261 attcctggta aggatttggg gcatagtttt ttgttttttt gagacggagt ttcgctcttg
     4321 ttgcccaagc tggagtgcag tggcgcgatc tcggctcact gcaacctccg cctcctgggt
     4381 tcaagcagtt ctcttgcctc agcctcccaa gtagctggga tgacaggcgc acaccaccac
     4441 gcccagcaaa ttttttgtat ttttagtaga aacgggattt caccttgtta ggctggtctc
     4501 gaactcctga cctcaggtga tccacccacc ttggcctccc aaagtgctgg gattacaggt
     4561 gtgagccacc acgcccggcc gatttggggc atttttattt aacagaactt ctctaacctt
     4621 ccaactgctt cccacaaaca cattggcctc aaggctcctt agaatcccag ttccagcttc
     4681 ctaaaataga cagtgggtat cgggcagcag tcactggggc tcaagggcag tgagcaagag
     4741 aaatgtctaa agctgcttct cccaacaccg tccaaagtct ccactgcctg agttttgttt
     4801 cggctggttt gaactcattt cgggtgtgtg catttttctt ttggtaccca tgtgagacat
     4861 gaacaacagg agggagggaa agagcccagg tgggacgtgg gacaggctta ggggaaagag
     4921 cttgtcctat ctcaggaaca aaattatagg ctgtgggcag agggtctgaa aggtgggctt
     4981 tggggtagtg cccaagcctg gtcgtgttgc caggagtggt gacaagaaat gcagcttaca
     5041 tcaaacgaac atgtagtgca tgcccactgc ctgatggcca gatggcctgt aggaagagct
     5101 accagggctt ccagacctgt ggaacgaaga ggatggggaa aaggcagagg gcactgagtg
     5161 tccctttaaa aactaaccca ctgaatattc cgtgtgatct agaacagtgt ggcagctttc
     5221 acagcacagg accgttcatc gggggcctaa acgtttccct cagctctgtc accaactcac
     5281 ttctctcggc ttcgttgtct gtaaattgga tgaaaagagc tctaatgcct ttcaggctct
     5341 tagaagccat agatttggac aagcccagca agatgggtgt ccttccaggc ctcttcccct
     5401 ttcctccatc tctggcaaca gttcttgggg tttggcaatt gtttggattt tttttctttc
     5461 tgcagttgtg tgtatgtgtg tttgtgtgaa gaaaaacaga ctctgtccag gtagaaatgg
     5521 tgaggagggg gaagagaatt acatttccag ggtcagaaac ttggcaacag ttttcctaga
     5581 gtgactcaga cacaccacag taacaactct cgctgcaatt ttattttaat ttgagaaata
     5641 aagatttcct ccaagccaca tgaggactct ggcacccacc cacaaagcaa gacctgtatt
     5701 tataagccga gggctcaggg agcctaactg cgggacccgt cagggccccg tgacccatcc
     5761 ccgtccccac ccccccctcc accgctgggc ccatcagtgt gtgttggggg gatgcttggc
     5821 agctgggggt gaggagacaa caaacctcgg gaactggagc cagagctgcg gcctgactga
     5881 cgccttttga tgctcacggg aaatttctgc ccaggatctc agccccaggc tggttgtttc
     5941 tacaaatctc tctcaaatgt attattttgg tgacaaaaat gaaggagctt tgtaaatttt
     6001 ttttaaaatt atgaatcata tcaagtagtt gtttacattt cttgaaaaaa taggaactcg
     6061 ggcagcagaa tcagattggc agaatcttta gactacacag gcaataatca agtctgctgt
     6121 tttggccttt cgtagtagaa gtggttgtag tgtttagata tctgtttggt cttgcttctt
     6181 gtattgcatt tttttcaata aacaacaaca aaaagaa
//
