LOCUS       NM_032048               5944 bp    mRNA    linear   PRI 07-FEB-2025
DEFINITION  Homo sapiens elastin microfibril interfacer 2 (EMILIN2), mRNA.
ACCESSION   NM_032048
VERSION     NM_032048.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5944)
  AUTHORS   Broniarczyk,J., Trejo-Cerro,O., Massimi,P., Kavcic,N., Myers,M.P.
            and Banks,L.
  TITLE     HPV-18 E6 enhances the interaction between EMILIN2 and SNX27 to
            promote WNT signaling
  JOURNAL   J Virol 98 (7), e0073524 (2024)
   PUBMED   38874360
  REMARK    GeneRIF: HPV-18 E6 enhances the interaction between EMILIN2 and
            SNX27 to promote WNT signaling.
REFERENCE   2  (bases 1 to 5944)
  AUTHORS   Tang,X. and Li,F.
  TITLE     Decreased EMILIN2 correlates to metabolism phenotype and poor
            prognosis of ovarian cancer
  JOURNAL   J Biochem 172 (2), 89-97 (2022)
   PUBMED   35588228
  REMARK    GeneRIF: Decreased EMILIN2 correlates to metabolism phenotype and
            poor prognosis of ovarian cancer.
REFERENCE   3  (bases 1 to 5944)
  AUTHORS   Wang,L.C., Cui,W.Y., Zhang,Z., Tan,Z.L., Lv,Q.L., Chen,S.H. and
            Shen,X.L.
  TITLE     Expression, methylation and prognostic feature of EMILIN2 in
            Low-Grade-Glioma
  JOURNAL   Brain Res Bull 175, 26-36 (2021)
   PUBMED   34280481
  REMARK    GeneRIF: Expression, methylation and prognostic feature of EMILIN2
            in Low-Grade-Glioma.
REFERENCE   4  (bases 1 to 5944)
  AUTHORS   Andreuzzi,E., Capuano,A., Pellicani,R., Poletto,E., Doliana,R.,
            Maiero,S., Fornasarig,M., Magris,R., Colombatti,A., Cannizzaro,R.,
            Spessotto,P. and Mongiat,M.
  TITLE     Loss of Multimerin-2 and EMILIN-2 Expression in Gastric Cancer
            Associate with Altered Angiogenesis
  JOURNAL   Int J Mol Sci 19 (12), 3983 (2018)
   PUBMED   30544909
  REMARK    GeneRIF: Loss of Multimerin-2 and EMILIN-2 Expression in Gastric
            Cancer Associate with Altered Angiogenesis
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5944)
  AUTHORS   Paulitti,A., Andreuzzi,E., Bizzotto,D., Pellicani,R.,
            Tarticchio,G., Marastoni,S., Pastrello,C., Jurisica,I.,
            Ligresti,G., Bucciotti,F., Doliana,R., Colladel,R., Braghetta,P.,
            Poletto,E., Di Silvestre,A., Bressan,G., Colombatti,A., Bonaldo,P.
            and Mongiat,M.
  TITLE     The ablation of the matricellular protein EMILIN2 causes defective
            vascularization due to impaired EGFR-dependent IL-8 production
            affecting tumor growth
  JOURNAL   Oncogene 37 (25), 3399-3414 (2018)
   PUBMED   29483644
  REMARK    GeneRIF: High EMILIN2 expression is associated with angiogenesis in
            B16 melanoma.
REFERENCE   6  (bases 1 to 5944)
  AUTHORS   Talmud,P.J., Drenos,F., Shah,S., Shah,T., Palmen,J., Verzilli,C.,
            Gaunt,T.R., Pallas,J., Lovering,R., Li,K., Casas,J.P., Sofat,R.,
            Kumari,M., Rodriguez,S., Johnson,T., Newhouse,S.J., Dominiczak,A.,
            Samani,N.J., Caulfield,M., Sever,P., Stanton,A., Shields,D.C.,
            Padmanabhan,S., Melander,O., Hastie,C., Delles,C., Ebrahim,S.,
            Marmot,M.G., Smith,G.D., Lawlor,D.A., Munroe,P.B., Day,I.N.,
            Kivimaki,M., Whittaker,J., Humphries,S.E. and Hingorani,A.D.
  CONSRTM   ASCOT investigators; NORDIL investigators; BRIGHT Consortium
  TITLE     Gene-centric association signals for lipids and apolipoproteins
            identified via the HumanCVD BeadChip
  JOURNAL   Am J Hum Genet 85 (5), 628-642 (2009)
   PUBMED   19913121
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 5944)
  AUTHORS   Doliana,R., Veljkovic,V., Prljic,J., Veljkovic,N., De Lorenzo,E.,
            Mongiat,M., Ligresti,G., Marastoni,S. and Colombatti,A.
  TITLE     EMILINs interact with anthrax protective antigen and inhibit toxin
            action in vitro
  JOURNAL   Matrix Biol 27 (2), 96-106 (2008)
   PUBMED   17988845
  REMARK    GeneRIF: EMILIN1 interacts with anthrax protective antigen and
            inhibits toxin action in vitro. EMILIN1 may be a potential target
            and/or a protein useful for countermeasures against B. anthracis
            toxin lethality.
REFERENCE   8  (bases 1 to 5944)
  AUTHORS   Mongiat,M., Ligresti,G., Marastoni,S., Lorenzon,E., Doliana,R. and
            Colombatti,A.
  TITLE     Regulation of the extrinsic apoptotic pathway by the extracellular
            matrix glycoprotein EMILIN2
  JOURNAL   Mol Cell Biol 27 (20), 7176-7187 (2007)
   PUBMED   17698584
  REMARK    GeneRIF: Results suggest that the expression of EMILIN2 triggers
            the apoptosis of different cell lines by activation of death
            receptors.
REFERENCE   9  (bases 1 to 5944)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   10 (bases 1 to 5944)
  AUTHORS   Doliana,R., Bot,S., Mungiguerra,G., Canton,A., Cilli,S.P. and
            Colombatti,A.
  TITLE     Isolation and characterization of EMILIN-2, a new component of the
            growing EMILINs family and a member of the EMI domain-containing
            superfamily
  JOURNAL   J Biol Chem 276 (15), 12003-12011 (2001)
   PUBMED   11278945
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP001011.6, AF270513.1, AI356740.1, AL552384.3, BX398832.2,
            AK090519.1 and AP000919.6.
            
            On Nov 24, 2018 this sequence version replaced NM_032048.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF270513.1, BC136541.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000254528.4/ ENSP00000254528.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-24                AP001011.6         204213-204236
            25-64               AF270513.1         1-40
            65-291              AI356740.1         32-258
            292-596             AF270513.1         268-572
            597-616             AL552384.3         343-362
            617-1815            AF270513.1         593-1791
            1816-1882           BX398832.2         1-67                c
            1883-2889           AF270513.1         1859-2865
            2890-4016           AK090519.1         961-2087
            4017-4033           AF270513.1         3993-4009
            4034-5944           AP000919.6         95377-97287
FEATURES             Location/Qualifiers
     source          1..5944
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
                     /map="18p11.32-p11.31"
     gene            1..5944
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /note="elastin microfibril interfacer 2"
                     /db_xref="GeneID:84034"
                     /db_xref="HGNC:HGNC:19881"
                     /db_xref="MIM:608928"
     exon            1..317
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /inference="alignment:Splign:2.1.0"
     CDS             184..3345
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /note="extracellular glycoprotein EMILIN-2; elastin
                     microfibril interface-located protein 2"
                     /codon_start=1
                     /product="EMILIN-2 precursor"
                     /protein_id="NP_114437.2"
                     /db_xref="CCDS:CCDS11828.1"
                     /db_xref="GeneID:84034"
                     /db_xref="HGNC:HGNC:19881"
                     /db_xref="MIM:608928"
                     /translation="MWQPRRPWPRVPWRWALALLALVGAGLCHAGPQPGYPARPSARN
                     KNWCAYIVNKNVSCSVLEGSESFIQAQYNCAWNQMPCPSALVYRVNFRPRYVTRYKTV
                     TQLEWRCCPGFRGGDCQEGPKDPVKTLRPTPARPRNSLKKATDNEPSQFSEPRKTLSP
                     TGTAQPSWGVDPKEGPQELQEKKIQVLEEKVLRLTRTVLDLQSSLAGVSENLKHATQD
                     DASRTRAPGLSSQHPKPDTTVSGDTETGQSPGVFNTKESGMKDIKSELAEVKDTLKNK
                     SDKLEELDGKVKGYEGQLRQLQEAAQGPTVTMTTNELYQAYVDSKIDALREELMEGMD
                     RKLADLKNSCEYKLTGLQQQCDDYGSSYLGVIELIGEKETSLRKEINNLRARLQEPSA
                     QANCCDSEKNGDIGQQIKTLDQKIERVAEATRMLNGRLDNEFDRLIVPEPDVDFDAKW
                     NELDARINVTEKNAEEHCFYIEETLRGAINGEVGDLKQLVDQKIQSLEDRLGSVLLQM
                     TNNTGAELSPPGAAALPGVSGSGDERVMMELNHLKDKVQVVEDICLLNIQGKPHGMEG
                     ALPNREDRAVRDSLHLLKSLNDTMHRKFQETEQTIQKLQQDFSFLYSQLNHTENDVTH
                     LQKEMSNCRAGENAGMGRFTKVGEQERTVDTLPSPQHPVAHCCSQLEERWQRLQSQVI
                     SELDACKECTQGVQREVSMVEGRVSHMEKTCSKLDSISGNLQRIKEGLNKHVSSLWNC
                     VRQMNGTLRSHSRDISGLKNSVQQFYSHVFQISTDLQDLVKFQPSAKAPSPPPPAEAP
                     KEPLQPEPAPPRPSGPATAEDPGRRPVLPQRPPEERPPQPPGSTGVIAETGQAGPPAG
                     AGVSGRGLPRGVDGQTGSGTVPGAEGFAGAPGYPKSPPVASPGAPVPSLVSFSAGLTQ
                     KPFPSDGGVVLFNKVLVNDGDVYNPSTGVFTAPYDGRYLITATLTPERDAYVEAVLSV
                     SNASVAQLHTAGYRREFLEYHRPPGALHTCGGPGAFHLIVHLKAGDAVNVVVTGGKLA
                     HTDFDEMYSTFSGVFLYPFLSHL"
     exon            318..440
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            441..616
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            617..2542
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2543..2845
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2846..2878
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            2879..3007
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /inference="alignment:Splign:2.1.0"
     exon            3008..5944
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3990..3995
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /note="hexamer: AATAAA"
     polyA_site      4018
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /note="major polyA site"
     regulatory      5911..5916
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
                     /note="hexamer: AATAAA"
     polyA_site      5944
                     /gene="EMILIN2"
                     /gene_synonym="EMILIN-2; FOAP-10"
ORIGIN      
        1 agaaggagaa gtaggaacga gaagccggag ggggcggccg cggagcactg gttggagcgc
       61 cgcgaagcgc ccgagcctct tgccttcgcg ggcggcgccc tggccgccgg cagccttgtg
      121 gccggtgccc cgatccgccg cgctccggac ccgggcaggc ggggcgcgcc cgctgcgcgc
      181 gggatgtggc agcccagacg gccctggccc cgcgtgccct ggcgctgggc gctggcgctg
      241 ctggccctgg ttggcgcggg gctgtgccac gccggcccgc agcccgggta tcccgcgcgg
      301 cccagcgcca ggaacaagaa ctggtgcgcc tacatcgtga acaagaatgt gagctgctcc
      361 gtgctggagg gaagtgagag ttttattcag gctcagtaca actgtgcctg gaaccagatg
      421 ccctgtccgt cggcgctggt gtatcgagtg aacttcagac ctagatatgt cactaggtat
      481 aagacagtga cacagttgga atggaggtgc tgtcctggct ttagaggggg agattgccaa
      541 gaaggtccca aagaccccgt gaagaccctc cgccccacgc cggctcggcc tcgaaacagc
      601 ttgaagaaag ccacagataa tgaacccagc caattctcag agcccaggaa gactttgtcc
      661 ccaactggta cagcacaacc aagctggggg gtagatccaa aagaggggcc tcaggaactt
      721 caggaaaaga agatacaggt gctagaggag aaggttcttc gactcacaag gacggttctt
      781 gacctccagt cttcccttgc tggagtgagt gaaaatctca aacatgccac tcaggatgat
      841 gccagtagaa cacgggcacc agggctcagc agccagcacc ccaagcctga caccactgtt
      901 agtggagaca cagaaacggg ccagagtcct ggtgtcttca acactaagga atctggcatg
      961 aaggacatca agtctgaatt ggctgaagtc aaagatactc taaagaacaa aagtgacaag
     1021 ctggaagagc tggatggaaa agtgaagggc tacgaagggc agctcagaca gctccaggaa
     1081 gcagctcagg gcccgacggt gaccatgaca accaacgaac tctaccaagc ctatgtggac
     1141 agtaagatcg acgccctgag agaggagctc atggagggca tggacagaaa gctggctgac
     1201 ctgaaaaact catgtgagta caagctcact ggcctccagc agcagtgtga tgactatggg
     1261 agcagctacc tgggagtgat agagctcata ggggagaagg aaacaagcct gagaaaagaa
     1321 ataaataacc tccgagcccg gctacaggag ccttcagccc aggcaaattg ctgcgacagt
     1381 gaaaagaatg gtgacattgg tcaacagatc aagacattgg accagaaaat cgagagagtt
     1441 gctgaagcca ccagaatgct gaatggaaga ctggacaatg agtttgaccg ccttatagtt
     1501 ccagagccag atgtggattt tgatgcaaaa tggaatgaac tcgatgcaag gatcaatgtg
     1561 acggagaaga acgctgaaga acattgcttt tacattgagg aaacccttcg gggcgccatt
     1621 aatggagagg tgggtgactt gaagcagctt gttgatcaga aaatacagtc tctggaagac
     1681 cgtctgggga gcgttctcct acagatgacc aataacactg gtgcagagct cagtccccca
     1741 ggggcagcag ccctgccagg agtgtcaggg tcaggagatg aacgggtcat gatggaatta
     1801 aaccacctga aggacaaagt tcaagttgtt gaagacattt gcctgctgaa catccaggga
     1861 aagcctcatg ggatggaagg tgccttgcca aacagggaag accgcgcagt acgcgacagc
     1921 ctgcaccttt tgaaatctct caacgacacg atgcacagga agtttcaaga aaccgaacaa
     1981 accatccaga aacttcaaca ggattttagt tttctttatt ctcaattaaa ccacacagaa
     2041 aatgatgtga ctcatcttca aaaggaaatg agcaattgta gagcaggtga aaacgctggc
     2101 atgggtaggt tcactaaggt gggtgagcaa gaaaggacag tggacaccct gccgtccccc
     2161 cagcaccccg tggctcattg ctgcagtcag ctggaggaga ggtggcagag gttgcagagc
     2221 caggtcatct cggagctgga tgcttgtaag gaatgcacgc agggggtcca gagggaggtc
     2281 tccatggtgg agggcagggt gtctcatatg gagaaaactt gcagcaagct ggactctatc
     2341 tcaggaaatc ttcagaggat caaggagggg ctcaacaagc atgtcagcag cctgtggaac
     2401 tgtgtcaggc agatgaacgg aacgctcagg tcgcattcca gagacatttc tggcctgaag
     2461 aattcagtcc agcagttcta cagccacgtc ttccagattt ctactgattt gcaagatctg
     2521 gtcaaatttc agccatcagc aaaggcgccc tcgcccccgc cgcccgcaga ggccccgaag
     2581 gagccgctgc agcccgagcc cgccccgccg aggcccagcg gccccgcaac cgcagaggac
     2641 cctgggcgac ggcccgtcct gccccagcgg ccccccgagg agaggccgcc ccagccgcca
     2701 ggctccaccg gggtcatcgc ggagacgggc caggccgggc cccccgcagg cgcaggcgtg
     2761 tctgggcggg gtctgccgcg gggcgtggac ggccagaccg ggagcggcac cgtccccggc
     2821 gcagaaggct tcgcgggcgc accaggatac ccgaagtcac ctcctgtagc ttccccagga
     2881 gctccggtgc cttctctggt gtctttttct gcggggctca cccagaagcc tttccccagt
     2941 gatgggggcg ttgtcctctt taacaaagtg ctggtgaacg acggggatgt ttacaacccc
     3001 agcaccgggg tcttcacggc tccttatgat gggcgctacc tgatcacggc caccctcacc
     3061 cccgagagag acgcctacgt ggaagcagtg ctgtcggtct ccaacgccag cgtggcccag
     3121 ctgcataccg ctgggtacag gagagagttc ctggaatacc accgccctcc aggagctttg
     3181 catacctgcg ggggcccggg ggcattccac ctcatcgtgc acctgaaggc gggagatgca
     3241 gtcaacgtcg tggtgactgg gggcaagctg gctcacacag actttgatga aatgtactcc
     3301 acatttagtg gggttttctt atatcctttc ctttcccacc tctaaggtgg ctggggagat
     3361 gtcaggggaa agatagatag ttgtaaaaac tctaaagctt taatatattc ggtttgtatg
     3421 taatggaagc acggggctag agtttccaca taggccccaa cataaaggcc ttccctcgct
     3481 gttgaggcca ccatgcctta ctgcatccag ccaggctgca gggagtgagg cacacggtga
     3541 acatggccac tgacttttct gccactctaa ctggacaact ggaagacttg gaaaggcctc
     3601 cacctgtatc tacactctga gggccctgga ctgggcctga gcttgccaca gaggctccgt
     3661 ctgactgtgg gctgggagga gggaggcagg ggagagccgg tcacggtggc tggtctttac
     3721 tgcagggcag cactgtggcc agctgtctgt ctttacactg catgcagaag tttaaacact
     3781 gaagtgccga agtggcccgt gccgccgcac agagaccccg actttagttt gggctgttcc
     3841 acgcttggct caccattgcc gcctgggact taacctgctc aggcgggcct tcgcccagct
     3901 gcaaataggg atgcgttaga gactgttccc aaagcttgtt gggctcctta aatggcatgt
     3961 acaatttaag tgcaaagaca gggagtgtca ataaagatgg aaagccattt ccagttaact
     4021 tttgttaatt taagtgtggt cccttacaga tcgggagttg ttgctaaaaa gcaaactgaa
     4081 gaaatgtttt gtttcaaaaa gggctacaga aagtaacctt gagtaaaatt aatctcagct
     4141 acaaaactgt tacccctccg catccaagct atacacttgg gttttgtttc tggcttgtga
     4201 agacggacca gatgtgcacg gaggtcaagg ccccatgtca tctgcagctg gagcggctcc
     4261 tctggggatg ctgcactcag atcccacagc agctgcccag gctaacttga tccctgctgc
     4321 ttcactgcac caatctccag cagacacagc tcgccgagct cttgggtttc taagcagcag
     4381 gaagctcaac ctaacgctgg ccacacgctg acagctgagc ccatctgaga acacggcatc
     4441 ttcacacagc gagacgcctc cactgagggg aggcccggga gtatcaatct gtcaccagtg
     4501 gccacggaga cctctcagca cccttagttc aaggtagtct ctgtggatca ggttggtaac
     4561 acctactggt taatcaagtc ccactgggga aaggtttgga cggtagaatc aagagctgca
     4621 gtttccttgg cccacaagat gctcttatgc tgtaaaaaaa atgctttaag aattgtttgc
     4681 aaatgaattt acagggtggc cactggacac ttcagagttc cttatttact ccccccgcca
     4741 cagctaggaa gaccagcaag aactaaaggt ttgccgtttt actatttaaa atgtggacct
     4801 ctttgtccag gagcgggagg gagaatggca tctcacccca ttacaacagc tggggaactg
     4861 gctaaagaga gctgtcagag agtatccttg gctgtcctag gaatgactca tggaaagcgc
     4921 cccagtgcag cagtgttttc aggaaaaccc agtgggcacg cgccatcgcc ctctcctctc
     4981 ctctcacgct ccttttgaaa agaccgcact cggcgcccaa ggggacgtgc tcaagagctg
     5041 caggggcagg gcccaggcaa aaggtgggtg atgactacct gctgctttcc ctactccgta
     5101 gatgggtctg gaacatcggg taaaacccag tcctcctctc agtgcatctc tactcaccaa
     5161 caatggtgaa tctcagctct gtgtattcaa gacaggcaaa acagaatatg cctcattatg
     5221 gctggagcgt gcctctactt tgagataaag ctggatgaca ggtggatcct ggcccactta
     5281 ggagacatct ttagaaaggg aaaggctgtc tttttgtaca ggtagtagaa caacaaggtc
     5341 agctgagctt aaggctgtgg ggttcgaagc agcccttcaa gaagtcatca cccctgaagt
     5401 agtgcctgcg agtcagtcag aggcatacca aaccctgaga cagaatcagg cacaagttca
     5461 caactttttt ttttttttgg ggggagacag tcctactctg tcgcccaggc tggagtgcag
     5521 tagcgcgatc tcagctcact gcaacctccg cctcccgggt tcaagcaatt ctcctacctc
     5581 agcctcccga gtagcgggga ctacaggtgc atgccgccac gcccggttaa ttttttgtat
     5641 tttagtagag atggggtttc accgtgttgc ccaggctggt cgcgaactcc tgagctcagc
     5701 caatccgccc acctcggcct cccaaagtgc tgggattaca ggtatgagcc accacgccca
     5761 gccaagttca caacttctga tatcaagttg ttgctgagaa aaggtcagga cacttcttaa
     5821 gtagagaagg actgtgacat cccctccaaa cctccatgta acactaacaa atggcctcat
     5881 ttacacgatt aaaaacaaaa tggtatcgtc aataaatgca aaccttaaac tgcatttgaa
     5941 atta
//
