LOCUS       XM_047433291            6225 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens eukaryotic translation initiation factor 4
            gamma 3 (EIF4G3), transcript variant X23, mRNA.
ACCESSION   XM_047433291
VERSION     XM_047433291.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6225
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..6225
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /note="eukaryotic translation initiation factor 4 gamma 3;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 68 ESTs, 1455 long SRA reads, 4
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 110 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:8672"
                     /db_xref="HGNC:HGNC:3298"
                     /db_xref="MIM:603929"
     CDS             333..5198
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 4 gamma
                     3 isoform X22"
                     /protein_id="XP_047289247.1"
                     /db_xref="GeneID:8672"
                     /db_xref="HGNC:HGNC:3298"
                     /db_xref="MIM:603929"
                     /translation="MNSQPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQA
                     NQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPG
                     DFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMS
                     GGGSRNPTPPIGRPTSTPTPPQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQE
                     EKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARS
                     TIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDI
                     CKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENP
                     PEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRV
                     LEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTW
                     KKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLKKVKAV
                     EENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQYD
                     REFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPRGPDFTPAFAD
                     FGRQTPGGRGVPICKVQSRHGLPILEQSKAPTCPPLVMSHPPMKSLPLGLLNVGSRRS
                     QPGQRREPRKIITVSVKEDVHLKKAENAWKPSQKRDSQADDPENIKTQELFRKVRSIL
                     NKLTPQMFNQLMKQVSGLTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLK
                     VPMADKPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDEL
                     EEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTI
                     GKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPK
                     TIEQIHKEAKIEEQEEQRKVQQLMTKEKRRPGVQRVDEGGWNTVQGAKNSRVLDPSKF
                     LKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASETDALRSSASSLNRFSALQPPAPS
                     GSTPSTPVEFDSRRTLTSRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLDNQSQEE
                     QRREMLETVKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKS
                     KSIIDEFLHINDFKEAMQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQL
                     VQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEF
                     SKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQ
                     KLDFIESDSPCSSEALSKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMS
                     SPTFLRALMTAVCKAAIIADSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQA
                     SIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTW
                     LREAEEESEDN"
ORIGIN      
        1 caatcccaca gagtattgat gaggaaactg aagtttggag cgatcacatc attttcccaa
       61 gaattcctag aggacctgtg caacaacctc ttgaggatcg aatcttcact cccgctgtct
      121 cagcagtcta cagcacggta acacaagtgg caagacagcc gggaacccct accccatccc
      181 cttattcagc acatgaaata aacaaggggc atccaaatct tgcggcaacg cccccgggac
      241 atgcatcgtc ccctggactc tctcaaaccc cttatccctc tggacagaat gcaggtccaa
      301 ccacgctggt ataccctcaa acccctcaga caatgaattc acaacctcaa acccgttctc
      361 cgtttttcca gaggcctcaa atacagcctc ctagagctac catcccgaac agcagtcctt
      421 ccattcgtcc tggtgcacag acacccactg cagtgtacca ggctaatcag cacatcatga
      481 tggttaacca tctgcccatg ccgtacccag tgccccaggg gcctcagtac tgtataccac
      541 agtaccgtca tagtggccct ccttatgttg ggccccccca acaatatcca gttcaaccac
      601 cggggccagg tcctttttat cctggaccag gacctgggga cttccccaat gcttatggaa
      661 cgccttttta cccaagtcag ccggtgtatc agtcagcacc tatcatagtg cctacgcagc
      721 aacagccgcc tccagccaag agagagaaaa aaactataag aattcgggat ccaaaccagg
      781 gaggtaaaga cataacagag gagattatgt ctggaggtgg cagcagaaat cctactccac
      841 ccataggaag acccacgtcc acacctactc ctcctcagct gcccagccag gtccccgagc
      901 acagccctgt ggtttatggg actgtggaga gcgctcatct tgctgccagc acccctgtca
      961 ctgcagctag cgaccagaag caagaggaga agccaaaacc agatccagtg ttaaagtctc
     1021 cttccccagt ccttaggcta gtcctcagtg gagagaagaa agaacaagaa ggccagacat
     1081 ctgaaactac tgcaatagta tccatagcag agcttcctct gcctccatca cctaccactg
     1141 tttcttctgt tgctcgaagt acaattgcag cccccacctc ttctgctctt agtagccaac
     1201 caatattcac cactgctata gatgacagat gtgaactctc atccccaaga gaagacacaa
     1261 ttcctatacc cagcctcaca tcttgcacag aaacatcaga ccctttacca acaaatgaaa
     1321 atgatgatga tatatgcaag aaaccctgta gtgtagcacc taatgatatt ccactggttt
     1381 ctagtactaa cctaattaat gaaataaatg gagttagcga aaaattatca gccacggaga
     1441 gcattgtgga aatagtaaaa caggaagtat tgccattgac tcttgaattg gagattctcg
     1501 aaaatccccc agaagaaatg aaactggagt gtatcccagc tcccatcacc ccttccacag
     1561 ttccttcctt tcctccaact cctccaactc ctccagcttc tcctcctcac actccagtca
     1621 ttgttcctgc tgctgccact actgttagtt ctccgagtgc tgccatcaca gtccagagag
     1681 tcctagagga ggacgagagc ataagaactt gccttagtga agatgcaaaa gagattcaga
     1741 acaaaataga ggtagaagca gatgggcaaa cagaagagat tttggattct caaaacttaa
     1801 attcaagaag gagccctgtc ccagctcaaa tagctataac tgtaccaaag acatggaaga
     1861 aaccaaaaga tcggacccga accactgaag agatgttaga ggcagaattg gagcttaaag
     1921 ctgaagagga gctttccatt gacaaagtac ttgaatctga acaagataaa atgagccagg
     1981 ggtttcatcc tgaaagagac ccctctgacc taaaaaaagt gaaagctgtg gaagaaaatg
     2041 gagaagaagc tgagccagta cgtaatggtg ctgagagtgt ttctgagggt gaaggaatag
     2101 atgctaattc aggctccaca gatagttctg gtgatggggt tacatttcca tttaaaccag
     2161 aatcctggaa gcctactgat actgaaggta agaagcagta tgacagggag tttctgctgg
     2221 acttccagtt catgcctgcc tgtatacaaa aaccagaggg cctgcctcct atcagtgatg
     2281 tggttcttga caagatcaac caacccaaat tgccaatgcg aactctggat cctcgaattt
     2341 tgcctcgagg accagacttt acaccagcct ttgctgattt tggaaggcag acacctggtg
     2401 gaagaggcgt acctatttgc aaagtgcaga gcaggcatgg attgccaatt ctggaacaga
     2461 gcaaagcccc aacttgccct ccactggtga tgtcacaccc acccatgaag agcctgcctc
     2521 tagggttgtt gaatgttggg tcacgaagat ctcaacctgg ccaaagaaga gaacccagaa
     2581 agatcatcac agtttctgta aaagaagatg tacacctgaa aaaggcagaa aatgcctgga
     2641 agccaagcca aaaacgagac agccaagccg atgatcccga aaacattaaa acccaggagc
     2701 tttttagaaa agttcgaagt atcttaaata aattgacacc acagatgttc aatcaactga
     2761 tgaagcaagt gtcaggactt actgttgaca cagaggagcg gctgaaagga gttattgacc
     2821 tggtctttga gaaggctatt gatgaaccca gtttctctgt ggcttacgca aacatgtgtc
     2881 gatgtctagt aacgctgaaa gtacccatgg cagacaagcc tggtaacaca gtgaatttcc
     2941 ggaagctgct actgaaccgt tgccagaagg agtttgaaaa agataaagca gatgatgatg
     3001 tctttgagaa gaagcagaaa gaacttgagg ctgccagtgc tccagaggag aggacaaggc
     3061 ttcatgatga actggaagaa gccaaggaca aagcccggcg gagatccatt ggcaacatca
     3121 agtttattgg agaactcttt aaactcaaaa tgctgactga agccatcatg catgactgtg
     3181 tggtgaagct gctaaagaac catgatgaag aatccctgga gtgcctgtgt cgcctgctca
     3241 ccaccattgg caaagacttg gactttgaaa aagcaaagcc acgtatggac cagtacttta
     3301 atcagatgga gaaaattgtg aaagaaagaa aaacctcatc taggattcgg ttcatgcttc
     3361 aagatgttat agacctaagg ctgtgcaatt gggtatctcg aagagcagat caagggccta
     3421 aaactatcga acagattcac aaagaggcta aaatagaaga acaagaagag caaaggaagg
     3481 tccagcaact catgaccaaa gagaagagaa gaccaggtgt ccagagagtg gacgaaggtg
     3541 ggtggaacac tgtacaaggg gccaagaaca gtcgggtact ggacccctca aaattcctaa
     3601 aaatcactaa gcctacaatt gatgaaaaaa ttcagctggt acctaaagca cagctaggca
     3661 gctggggaaa aggcagcagt ggtggagcaa aggcaagtga gactgatgcc ttacggtcaa
     3721 gtgcttccag tttaaacaga ttctctgccc tgcaacctcc agcaccctca gggtccacgc
     3781 catccacgcc tgtagagttt gattcccgaa ggaccttaac tagtcgtgga agtatgggca
     3841 gggagaagaa tgacaagccc cttccatctg caacagctcg gccaaatact ttcatgaggg
     3901 gtggcagcag taaagacctg ctagacaatc agtctcaaga agagcagcgg agagagatgc
     3961 tggagaccgt gaagcagctc acaggaggtg tggatgtgga gaggaacagc actgaggctg
     4021 agcgaaataa aacaagggag tcagcaaaac cagaaatttc agcaatgtca gctcatgaca
     4081 aggctgcatt atcagaagag gaactggaga ggaagtcgaa atctatcatt gatgaatttc
     4141 tacacattaa tgattttaag gaagccatgc agtgtgtgga agagctgaat gcccagggcc
     4201 tactacatgt ttttgtgaga gtgggagtgg agtccaccct ggaaaggagc cagatcacca
     4261 gggatcacat gggccaatta ctctatcagc tggtacagtc agaaaaactc agcaaacagg
     4321 actttttcaa aggtttttca gaaactttgg aattggcaga tgacatggcc attgatattc
     4381 cccatatttg gttgtacctt gctgaactgg tgacccccat gttaaaagaa ggtggaatct
     4441 ccatgagaga acttaccata gaatttagca aacctttact tcctgttgga agagctgggg
     4501 tcttgctatc tgaaatattg cacctactat gcaaacaaat gagccataag aaagtgggag
     4561 ccttatggag ggaggctgac ctcagctgga aggacttttt accagaagga gaagatgtac
     4621 ataattttct tttggagcag aagttggact tcatagagtc tgacagtccc tgttcctctg
     4681 aagcactttc aaagaaagaa ctgtctgccg aagagctgta taagcgactc gagaaactca
     4741 ttattgagga caaagcgaat gatgaacaga tctttgactg ggtagaggct aatctagacg
     4801 aaatccagat gagttcacct acattcctta gagctttaat gactgctgtt tgtaaagcag
     4861 ctattatagc cgactcttct accttcagag tggacactgc tgttatcaag cagagagtgc
     4921 cgatcttact caagtaccta gactcagata cagagaagga actgcaagca ctttatgcac
     4981 tacaagcatc gatagtaaaa cttgatcaac ctgccaattt gctgcggatg ttttttgatt
     5041 gtctatatga cgaggaggtg atctccgagg atgccttcta caaatgggag agcagcaagg
     5101 accctgcaga gcagaatggg aagggcgtgg ctctgaaatc tgtcacggca ttcttcacgt
     5161 ggctgcggga agcagaagag gagtctgagg ataactaaaa cttcaaatac acaaaatgaa
     5221 acaaaagaaa caatttaagt atttttttaa aaagtttcac gtcttcgcca atcacagtgc
     5281 agcaaggcca attctcgcag aaacccccac gtgtgcacga gtgggagagg ggaaagagaa
     5341 aaaaaggtga tcatggagga aaaaggtact ggataaaagt aaacttcaaa ccttagggcg
     5401 ggagcactaa aaccaaaata catgtattat ttatagaaaa tattttctgt tttaatcttt
     5461 tctttttaaa caaggactca tacttaaaaa aatgtttagc aaaaaaaaaa aaagttgaga
     5521 acttttaatt tattttaagg actgcaaatg ccagtgtaat tttttaattt gcagtttctg
     5581 taaacaactt gtataataga aaagcagaga aataaatttc cctccccttc aagatgcacc
     5641 tcatgtttgt tttaaggtat agcatttagt ccagatttga gaaagtttgg ggtgaacaag
     5701 gtaagaaaga tttttttttt tttggcatca aatctttctg cctgcctctc agcttgcttc
     5761 agaaaattta aaaaatcaca atagtaatca aaacatacat aacattgaaa cagaaggaaa
     5821 tgctgtggac cacagaactc caagaattgt ttaaaaaaaa aaaagtgcta ccctgagaaa
     5881 agtactctta atactcttga aatctttaga gcaactttaa ggcttgtaaa tacatagaac
     5941 aaatatttaa aaaaacaaaa agaaattgac tcagtactat ttcttttcac tttgaaaata
     6001 taaagaacaa aataaagaca aacattgcaa gtttaaaaga aagtaaagtg acttctcctt
     6061 tggacagctg ctgcatgtgt gcccattcct gggggtgctg tctggctatt tattgtctaa
     6121 ttcaaatcac tcctgagggg agagagataa aacgagagag agtgagagag tgtgtgtatg
     6181 tgcgtgtatg cgcacgtatg tgcatgcaca tgtatgtatg tatat
//
