LOCUS       XM_017002677            6342 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens eukaryotic translation initiation factor 4
            gamma 3 (EIF4G3), transcript variant X7, mRNA.
ACCESSION   XM_017002677
VERSION     XM_017002677.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017002677.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6342
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..6342
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /note="eukaryotic translation initiation factor 4 gamma 3;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 70 ESTs, 1435 long SRA reads, 4
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 99 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:8672"
                     /db_xref="HGNC:HGNC:3298"
                     /db_xref="MIM:603929"
     CDS             333..5315
                     /gene="EIF4G3"
                     /gene_synonym="eIF-4G 3; eIF4G 3; eIF4GII"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 4 gamma
                     3 isoform X6"
                     /protein_id="XP_016858166.1"
                     /db_xref="GeneID:8672"
                     /db_xref="HGNC:HGNC:3298"
                     /db_xref="MIM:603929"
                     /translation="MNSQPQTRSPPSRTVPIHCTDNWKRRKVLEQTPVYRSLAGRGWI
                     KYCIFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGP
                     QYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSA
                     PIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTP
                     PQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLV
                     LSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTA
                     IDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTN
                     LINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVP
                     SFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQ
                     NKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTWKKPKDRTRTTEEMLEAELE
                     LKAEEELSIDKVLESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEPVRNGAESVSE
                     GEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACIQKPEG
                     LPPISDVVLDKINQPKLPMRTLDPRILPRGPDFTPAFADFGRQTPGGRGVPICKVQSR
                     HGLPILEQSKAPTCPPLVMSHPPMKSLPLGLLNVGSRRSQPGQRREPRKIITVSVKED
                     VHLKKAENAWKPSQKRDSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLT
                     VDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLN
                     RCQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIG
                     ELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQ
                     MEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRK
                     VQQLMTKEKRRPGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVPKAQ
                     LGSWGKGSSGGAKASETDALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLTSR
                     GSMGREKNDKPLPSATARPNTFMRGGSSKDLLDNQSQEEQRREMLETVKQLTGGVDVE
                     RNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHINDFKEAMQC
                     VEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFFKGFSETL
                     ELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILH
                     LLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEALSKK
                     ELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIA
                     DSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCL
                     YDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN"
ORIGIN      
        1 caatcccaca gagtattgat gaggaaactg aagtttggag cgatcacatc attttcccaa
       61 gaattcctag aggacctgtg caacaacctc ttgaggatcg aatcttcact cccgctgtct
      121 cagcagtcta cagcacggta acacaagtgg caagacagcc gggaacccct accccatccc
      181 cttattcagc acatgaaata aacaaggggc atccaaatct tgcggcaacg cccccgggac
      241 atgcatcgtc ccctggactc tctcaaaccc cttatccctc tggacagaat gcaggtccaa
      301 ccacgctggt ataccctcaa acccctcaga caatgaattc acaacctcaa acccgttctc
      361 cgcccagcag aacagtgcca atacattgca cagacaactg gaagaggagg aaggttttgg
      421 aacagactcc cgtttacagg tccttggctg gaagaggctg gataaaatac tgcatttttt
      481 tccagaggcc tcaaatacag cctcctagag ctaccatccc gaacagcagt ccttccattc
      541 gtcctggtgc acagacaccc actgcagtgt accaggctaa tcagcacatc atgatggtta
      601 accatctgcc catgccgtac ccagtgcccc aggggcctca gtactgtata ccacagtacc
      661 gtcatagtgg ccctccttat gttgggcccc cccaacaata tccagttcaa ccaccggggc
      721 caggtccttt ttatcctgga ccaggacctg gggacttccc caatgcttat ggaacgcctt
      781 tttacccaag tcagccggtg tatcagtcag cacctatcat agtgcctacg cagcaacagc
      841 cgcctccagc caagagagag aaaaaaacta taagaattcg ggatccaaac cagggaggta
      901 aagacataac agaggagatt atgtctggag gtggcagcag aaatcctact ccacccatag
      961 gaagacccac gtccacacct actcctcctc agcagctgcc cagccaggtc cccgagcaca
     1021 gccctgtggt ttatgggact gtggagagcg ctcatcttgc tgccagcacc cctgtcactg
     1081 cagctagcga ccagaagcaa gaggagaagc caaaaccaga tccagtgtta aagtctcctt
     1141 ccccagtcct taggctagtc ctcagtggag agaagaaaga acaagaaggc cagacatctg
     1201 aaactactgc aatagtatcc atagcagagc ttcctctgcc tccatcacct accactgttt
     1261 cttctgttgc tcgaagtaca attgcagccc ccacctcttc tgctcttagt agccaaccaa
     1321 tattcaccac tgctatagat gacagatgtg aactctcatc cccaagagaa gacacaattc
     1381 ctatacccag cctcacatct tgcacagaaa catcagaccc tttaccaaca aatgaaaatg
     1441 atgatgatat atgcaagaaa ccctgtagtg tagcacctaa tgatattcca ctggtttcta
     1501 gtactaacct aattaatgaa ataaatggag ttagcgaaaa attatcagcc acggagagca
     1561 ttgtggaaat agtaaaacag gaagtattgc cattgactct tgaattggag attctcgaaa
     1621 atcccccaga agaaatgaaa ctggagtgta tcccagctcc catcacccct tccacagttc
     1681 cttcctttcc tccaactcct ccaactcctc cagcttctcc tcctcacact ccagtcattg
     1741 ttcctgctgc tgccactact gttagttctc cgagtgctgc catcacagtc cagagagtcc
     1801 tagaggagga cgagagcata agaacttgcc ttagtgaaga tgcaaaagag attcagaaca
     1861 aaatagaggt agaagcagat gggcaaacag aagagatttt ggattctcaa aacttaaatt
     1921 caagaaggag ccctgtccca gctcaaatag ctataactgt accaaagaca tggaagaaac
     1981 caaaagatcg gacccgaacc actgaagaga tgttagaggc agaattggag cttaaagctg
     2041 aagaggagct ttccattgac aaagtacttg aatctgaaca agataaaatg agccaggggt
     2101 ttcatcctga aagagacccc tctgacctaa aaaaagtgaa agctgtggaa gaaaatggag
     2161 aagaagctga gccagtacgt aatggtgctg agagtgtttc tgagggtgaa ggaatagatg
     2221 ctaattcagg ctccacagat agttctggtg atggggttac atttccattt aaaccagaat
     2281 cctggaagcc tactgatact gaaggtaaga agcagtatga cagggagttt ctgctggact
     2341 tccagttcat gcctgcctgt atacaaaaac cagagggcct gcctcctatc agtgatgtgg
     2401 ttcttgacaa gatcaaccaa cccaaattgc caatgcgaac tctggatcct cgaattttgc
     2461 ctcgaggacc agactttaca ccagcctttg ctgattttgg aaggcagaca cctggtggaa
     2521 gaggcgtacc tatttgcaaa gtgcagagca ggcatggatt gccaattctg gaacagagca
     2581 aagccccaac ttgccctcca ctggtgatgt cacacccacc catgaagagc ctgcctctag
     2641 ggttgttgaa tgttgggtca cgaagatctc aacctggcca aagaagagaa cccagaaaga
     2701 tcatcacagt ttctgtaaaa gaagatgtac acctgaaaaa ggcagaaaat gcctggaagc
     2761 caagccaaaa acgagacagc caagccgatg atcccgaaaa cattaaaacc caggagcttt
     2821 ttagaaaagt tcgaagtatc ttaaataaat tgacaccaca gatgttcaat caactgatga
     2881 agcaagtgtc aggacttact gttgacacag aggagcggct gaaaggagtt attgacctgg
     2941 tctttgagaa ggctattgat gaacccagtt tctctgtggc ttacgcaaac atgtgtcgat
     3001 gtctagtaac gctgaaagta cccatggcag acaagcctgg taacacagtg aatttccgga
     3061 agctgctact gaaccgttgc cagaaggagt ttgaaaaaga taaagcagat gatgatgtct
     3121 ttgagaagaa gcagaaagaa cttgaggctg ccagtgctcc agaggagagg acaaggcttc
     3181 atgatgaact ggaagaagcc aaggacaaag cccggcggag atccattggc aacatcaagt
     3241 ttattggaga actctttaaa ctcaaaatgc tgactgaagc catcatgcat gactgtgtgg
     3301 tgaagctgct aaagaaccat gatgaagaat ccctggagtg cctgtgtcgc ctgctcacca
     3361 ccattggcaa agacttggac tttgaaaaag caaagccacg tatggaccag tactttaatc
     3421 agatggagaa aattgtgaaa gaaagaaaaa cctcatctag gattcggttc atgcttcaag
     3481 atgttataga cctaaggctg tgcaattggg tatctcgaag agcagatcaa gggcctaaaa
     3541 ctatcgaaca gattcacaaa gaggctaaaa tagaagaaca agaagagcaa aggaaggtcc
     3601 agcaactcat gaccaaagag aagagaagac caggtgtcca gagagtggac gaaggtgggt
     3661 ggaacactgt acaaggggcc aagaacagtc gggtactgga cccctcaaaa ttcctaaaaa
     3721 tcactaagcc tacaattgat gaaaaaattc agctggtacc taaagcacag ctaggcagct
     3781 ggggaaaagg cagcagtggt ggagcaaagg caagtgagac tgatgcctta cggtcaagtg
     3841 cttccagttt aaacagattc tctgccctgc aacctccagc accctcaggg tccacgccat
     3901 ccacgcctgt agagtttgat tcccgaagga ccttaactag tcgtggaagt atgggcaggg
     3961 agaagaatga caagcccctt ccatctgcaa cagctcggcc aaatactttc atgaggggtg
     4021 gcagcagtaa agacctgcta gacaatcagt ctcaagaaga gcagcggaga gagatgctgg
     4081 agaccgtgaa gcagctcaca ggaggtgtgg atgtggagag gaacagcact gaggctgagc
     4141 gaaataaaac aagggagtca gcaaaaccag aaatttcagc aatgtcagct catgacaagg
     4201 ctgcattatc agaagaggaa ctggagagga agtcgaaatc tatcattgat gaatttctac
     4261 acattaatga ttttaaggaa gccatgcagt gtgtggaaga gctgaatgcc cagggcctac
     4321 tacatgtttt tgtgagagtg ggagtggagt ccaccctgga aaggagccag atcaccaggg
     4381 atcacatggg ccaattactc tatcagctgg tacagtcaga aaaactcagc aaacaggact
     4441 ttttcaaagg tttttcagaa actttggaat tggcagatga catggccatt gatattcccc
     4501 atatttggtt gtaccttgct gaactggtga cccccatgtt aaaagaaggt ggaatctcca
     4561 tgagagaact taccatagaa tttagcaaac ctttacttcc tgttggaaga gctggggtct
     4621 tgctatctga aatattgcac ctactatgca aacaaatgag ccataagaaa gtgggagcct
     4681 tatggaggga ggctgacctc agctggaagg actttttacc agaaggagaa gatgtacata
     4741 attttctttt ggagcagaag ttggacttca tagagtctga cagtccctgt tcctctgaag
     4801 cactttcaaa gaaagaactg tctgccgaag agctgtataa gcgactcgag aaactcatta
     4861 ttgaggacaa agcgaatgat gaacagatct ttgactgggt agaggctaat ctagacgaaa
     4921 tccagatgag ttcacctaca ttccttagag ctttaatgac tgctgtttgt aaagcagcta
     4981 ttatagccga ctcttctacc ttcagagtgg acactgctgt tatcaagcag agagtgccga
     5041 tcttactcaa gtacctagac tcagatacag agaaggaact gcaagcactt tatgcactac
     5101 aagcatcgat agtaaaactt gatcaacctg ccaatttgct gcggatgttt tttgattgtc
     5161 tatatgacga ggaggtgatc tccgaggatg ccttctacaa atgggagagc agcaaggacc
     5221 ctgcagagca gaatgggaag ggcgtggctc tgaaatctgt cacggcattc ttcacgtggc
     5281 tgcgggaagc agaagaggag tctgaggata actaaaactt caaatacaca aaatgaaaca
     5341 aaagaaacaa tttaagtatt tttttaaaaa gtttcacgtc ttcgccaatc acagtgcagc
     5401 aaggccaatt ctcgcagaaa cccccacgtg tgcacgagtg ggagagggga aagagaaaaa
     5461 aaggtgatca tggaggaaaa aggtactgga taaaagtaaa cttcaaacct tagggcggga
     5521 gcactaaaac caaaatacat gtattattta tagaaaatat tttctgtttt aatcttttct
     5581 ttttaaacaa ggactcatac ttaaaaaaat gtttagcaaa aaaaaaaaaa gttgagaact
     5641 tttaatttat tttaaggact gcaaatgcca gtgtaatttt ttaatttgca gtttctgtaa
     5701 acaacttgta taatagaaaa gcagagaaat aaatttccct ccccttcaag atgcacctca
     5761 tgtttgtttt aaggtatagc atttagtcca gatttgagaa agtttggggt gaacaaggta
     5821 agaaagattt tttttttttt ggcatcaaat ctttctgcct gcctctcagc ttgcttcaga
     5881 aaatttaaaa aatcacaata gtaatcaaaa catacataac attgaaacag aaggaaatgc
     5941 tgtggaccac agaactccaa gaattgttta aaaaaaaaaa agtgctaccc tgagaaaagt
     6001 actcttaata ctcttgaaat ctttagagca actttaaggc ttgtaaatac atagaacaaa
     6061 tatttaaaaa aacaaaaaga aattgactca gtactatttc ttttcacttt gaaaatataa
     6121 agaacaaaat aaagacaaac attgcaagtt taaaagaaag taaagtgact tctcctttgg
     6181 acagctgctg catgtgtgcc cattcctggg ggtgctgtct ggctatttat tgtctaattc
     6241 aaatcactcc tgaggggaga gagataaaac gagagagagt gagagagtgt gtgtatgtgc
     6301 gtgtatgcgc acgtatgtgc atgcacatgt atgtatgtat at
//
