LOCUS       NM_006360               5047 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens eukaryotic translation initiation factor 3 subunit M
            (EIF3M), transcript variant 1, mRNA.
ACCESSION   NM_006360
VERSION     NM_006360.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5047)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   2  (bases 1 to 5047)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 5047)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 5047)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   5  (bases 1 to 5047)
  AUTHORS   Lee,A.S., Kranzusch,P.J. and Cate,J.H.
  TITLE     eIF3 targets cell-proliferation messenger RNAs for translational
            activation or repression
  JOURNAL   Nature 522 (7554), 111-114 (2015)
   PUBMED   25849773
REFERENCE   6  (bases 1 to 5047)
  AUTHORS   Hinnebusch,A.G.
  TITLE     eIF3: a versatile scaffold for translation initiation complexes
  JOURNAL   Trends Biochem Sci 31 (10), 553-562 (2006)
   PUBMED   16920360
  REMARK    Review article
REFERENCE   7  (bases 1 to 5047)
  AUTHORS   Stelzl,U., Worm,U., Lalowski,M., Haenig,C., Brembeck,F.H.,
            Goehler,H., Stroedicke,M., Zenkner,M., Schoenherr,A., Koeppen,S.,
            Timm,J., Mintzlaff,S., Abraham,C., Bock,N., Kietzmann,S.,
            Goedde,A., Toksoz,E., Droege,A., Krobitsch,S., Korn,B.,
            Birchmeier,W., Lehrach,H. and Wanker,E.E.
  TITLE     A human protein-protein interaction network: a resource for
            annotating the proteome
  JOURNAL   Cell 122 (6), 957-968 (2005)
   PUBMED   16169070
REFERENCE   8  (bases 1 to 5047)
  AUTHORS   Perez-Romero,P. and Fuller,A.O.
  TITLE     The C terminus of the B5 receptor for herpes simplex virus contains
            a functional region important for infection
  JOURNAL   J Virol 79 (12), 7431-7437 (2005)
   PUBMED   15919899
  REMARK    GeneRIF: Concluded that the C terminus of B5 contains a functional
            region that is important for the B5 receptor to mediate events in
            HSV entry.
REFERENCE   9  (bases 1 to 5047)
  AUTHORS   Perez,A., Li,Q.X., Perez-Romero,P., Delassus,G., Lopez,S.R.,
            Sutter,S., McLaren,N. and Fuller,A.O.
  TITLE     A new class of receptor for herpes simplex virus has heptad repeat
            motifs that are common to membrane fusion proteins
  JOURNAL   J Virol 79 (12), 7419-7430 (2005)
   PUBMED   15919898
  REMARK    GeneRIF: Cloned a previously uncharacterized human gene, designated
            hfl-B5, and showed that it encodes a type II cell surface membrane
            protein that can serve as a receptor for entry of HSV.
REFERENCE   10 (bases 1 to 5047)
  AUTHORS   Lehner,B. and Sanderson,C.M.
  TITLE     A protein interaction framework for human mRNA degradation
  JOURNAL   Genome Res 14 (7), 1315-1323 (2004)
   PUBMED   15231747
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB479224.1, BC019103.2, AK304378.1, BE935691.1, CK002866.1 and
            AL078477.5.
            
            On Nov 22, 2018 this sequence version replaced NM_006360.5.
            
            Summary: This gene encodes a protein that is part of the
            eurkaryotic translation initiation factor 3 complete (eIF-3)
            required for protein synthesis. Elevated levels of the encoded
            protein are present in cancer cell lines. Inactivation of the
            encoded protein has been shown to interfere with translation of
            herpes virus mRNAs by preventing the association of mRNAs with the
            ribosomes. A pseudogene of this gene is located on the X
            chromosome. [provided by RefSeq, Dec 2011].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803617.234014.1,
                                           SRR1803611.13609.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000531120.6/ ENSP00000436049.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-14                DB479224.1         65-78
            15-1256             BC019103.2         1-1242
            1257-1606           AK304378.1         861-1210
            1607-1638           BE935691.1         1-32                c
            1639-1651           CK002866.1         645-657
            1652-5047           AL078477.5         58973-62368         c
FEATURES             Location/Qualifiers
     source          1..5047
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p13"
     gene            1..5047
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /note="eukaryotic translation initiation factor 3 subunit
                     M"
                     /db_xref="GeneID:10480"
                     /db_xref="HGNC:HGNC:24460"
                     /db_xref="MIM:609641"
     exon            1..99
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..1182
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /EC_number="3.6.5.3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     dendritic cell protein; PCI domain containing 1
                     (herpesvirus entry mediator); fetal lung protein B5; B5
                     receptor; PCI domain-containing protein 1; transport and
                     golgi organization 7 homolog"
                     /codon_start=1
                     /product="eukaryotic translation initiation factor 3
                     subunit M isoform 1"
                     /protein_id="NP_006351.2"
                     /db_xref="CCDS:CCDS7880.1"
                     /db_xref="GeneID:10480"
                     /db_xref="HGNC:HGNC:24460"
                     /db_xref="MIM:609641"
                     /translation="MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQ
                     IIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLR
                     LQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEK
                     KHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAF
                     LFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAK
                     MRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVV
                     SHSTHRTFGKQQWQQLYDTLNAWKQNLNKVKNSLLSLSDT"
     exon            100..232
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /inference="alignment:Splign:2.1.0"
     exon            233..371
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /inference="alignment:Splign:2.1.0"
     exon            372..495
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /inference="alignment:Splign:2.1.0"
     exon            496..590
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /inference="alignment:Splign:2.1.0"
     exon            591..674
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /inference="alignment:Splign:2.1.0"
     exon            675..774
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /inference="alignment:Splign:2.1.0"
     exon            775..856
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /inference="alignment:Splign:2.1.0"
     exon            857..1000
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1061
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..5047
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1242..1247
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /note="hexamer: TATAAA"
     polyA_site      1256
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /note="major polyA site"
     regulatory      2390..2395
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /note="hexamer: ATTAAA"
     polyA_site      2418
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
     regulatory      3281..3286
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /note="hexamer: ATTAAA"
     polyA_site      3299
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
     regulatory      3552..3557
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /note="hexamer: ATTAAA"
     polyA_site      3582
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
     regulatory      5023..5028
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
                     /note="hexamer: AATAAA"
     polyA_site      5047
                     /gene="EIF3M"
                     /gene_synonym="B5; GA17; hfl-B5; PCID1; TANGO7"
ORIGIN      
        1 cttttccggt cggcgtggtc ttgcgagtgg agtgtccgct gtgcccgggc ctgcaccatg
       61 agcgtcccgg ccttcatcga catcagtgaa gaagatcagg ctgctgagct tcgtgcttat
      121 ctgaaatcta aaggagctga gatttcagaa gagaactcgg aaggtggact tcatgttgat
      181 ttagctcaaa ttattgaagc ctgtgatgtg tgtctgaagg aggatgataa agatgttgaa
      241 agtgtgatga acagtgtggt atccctactc ttgatcctgg aaccagacaa gcaagaagct
      301 ttgattgaaa gcctatgtga aaagctggtc aaatttcgcg aaggtgaacg cccgtctctg
      361 agactgcagt tgttaagcaa ccttttccac gggatggata agaatactcc tgtaagatac
      421 acagtgtatt gcagccttat taaagtggca gcatcttgtg gggccatcca gtacatccca
      481 actgagctgg atcaagttag aaaatggatt tctgactgga atctcaccac tgaaaaaaag
      541 cacacccttt taagactact ttatgaggca cttgtggatt gtaagaagag tgatgctgct
      601 tcaaaagtca tggtggaatt gctcggaagt tacacagagg acaatgcttc ccaggctcga
      661 gttgatgccc acaggtgtat tgtacgagca ttgaaagatc caaatgcatt tctttttgac
      721 caccttctta ctttaaaacc agtcaagttt ttggaaggcg agcttattca tgatctttta
      781 accatttttg tgagtgctaa attggcatca tatgtcaagt tttatcagaa taataaagac
      841 ttcattgatt cacttggcct gttacatgaa cagaatatgg caaaaatgag actacttact
      901 tttatgggaa tggcagtaga aaataaggaa atttcttttg acacaatgca gcaagaactt
      961 cagattggag ctgatgatgt tgaagcattt gttattgacg ccgtaagaac taaaatggtc
     1021 tactgcaaaa ttgatcagac ccagagaaaa gtagttgtca gtcatagcac acatcggaca
     1081 tttggaaaac agcagtggca acaactgtat gacacactta atgcctggaa acaaaatctg
     1141 aacaaagtga aaaacagcct tttgagtctt tctgatacct gagtttttat gcttataatt
     1201 tttgttcttt gaaaaaaaag ccctaaatca tagtaaaaca ttataaacta aaaaaatttg
     1261 cctagtctgg acagttattg tctcaaattt atactaaaat cacaaactcc agaggatatg
     1321 aagtaataaa ttacaagggg tcacaatgtc tgtcatacaa tacataaatt ctgttcttta
     1381 aaaaaggata ttgaagaagc aatgagcact ttaaagaaag gataatatac agagagaaga
     1441 cagaagtaga gtaatacaat ttcttcacat tagaaaaact tggaaaagca aagacaaact
     1501 gtagagcttt aaatacaaca gtcattttat tctagtaaaa actataccag aatttcagtt
     1561 acataatttc actactgaaa gcacttatct acattatttt aatctgttgt ttttttccaa
     1621 cgtctcttct gcttttcttt tctttggctg gttgtcattt tctaaactta gtaaattttc
     1681 acttttattt agttgattcg taatgaggct ctgccagtca tcatcaccag aagtattttt
     1741 agtcgtcttg attgcctgca aatggctttg tagtggagtt gatatcagag gctttgtttt
     1801 cacctgggaa agataaacta attttacctt cgaaattatt atacaaaaga ttttaaagag
     1861 tctgtaaagc ctctgcagtt atgagtatgt ggtaaaacca ccatctcttg gctgatttcc
     1921 actaccttag tagttctggc accagaaaag tatacaatgt gaatgtgtag gcttatgtag
     1981 tagatcttca aaatctctaa tatataactg aagtaaagtg tacaaaaact gccttttact
     2041 acttcatgtt tcctcccatg cttcagaaca ccattgttga agaaacagga agggcagtga
     2101 gatatttgga agttggcatg ttttcaagac actgtattgg gtaattttaa aaatagtgtg
     2161 ttaaataact ttttcatttt aaggttcttt tctgatgtta aaatacttac tggaaattta
     2221 gaaaatagag taaagtagaa agaaactaaa aatcattagt aatcccttat ccagagaggc
     2281 ttgttgacat tttggtatta tttgctgcta gcgttttttt ctatttttag cctatttgat
     2341 cattctatag aattttatgt attttcctct gtgagcagtt tcttaggtca ttaaaaacaa
     2401 ttgtctatgg ctgcaaaata ctccctttta tggatgtttg atatatctcc tactactgaa
     2461 tgtttgtttc cagtttatcc ctaccaaaaa ttaattcgag ttaatttcat gcaaaacaat
     2521 ctttgatgtt tttgagagat tcccagataa aattttctct tcaaaaggaa tactgggcca
     2581 ggcactgtga ctcatacctg taatcccagc actttgggaa actgaggcga gtggattgca
     2641 tgagctcagg agtcgaaaac tagcctgagc aacatggcaa aaccccatct ctaccaaaaa
     2701 ttagctgggc atggtggcat gcaactgtag tcccagctcc tcggagggct gaggtgcaag
     2761 gatcatttga gcccaggagg tgaaggttgc aatgagccaa gatcatgcca ttgcactcca
     2821 gcctggacaa cagagtgaga ccctctctca aaaataaata atagataaaa caaaaggaat
     2881 actgaattgt tttcaaaata acaattatgg tgggctttct tttaagatag ggtctcaccc
     2941 tgtcacctag gctggagtgc agtggcacaa tcacagctca ttgcagcctt gacctccctg
     3001 gattcaggtg atcctcccac cttcacctcc tgagtacctt ggactacagg catgtgccac
     3061 cacacccagg taatttttgt attttttgcc atgttgccca ggctggtctc tcttaactct
     3121 tgggctcaag tgatctgacc atctcggtct cccaaagttc taggattaca ggagtgagcc
     3181 atactgtgtt gtgttttagt tgaaagggat atacacgtgt attttagaaa tatgaaacag
     3241 gataagaatt acattaaaat cacccaagat cccaaccacc attaaagagt ttgtgtaaat
     3301 cttctggtct cttttctgta tacacttttt aaatactggg gtcatatttt tattggttta
     3361 tatgctatgt taaacatttt tagcatttcc tcctgttctt aagtctgtta agaggatagc
     3421 tccatcatat tctgtgttct gcaaattatt tctggacatt taaattgtaa gaaaatggtc
     3481 actgttaact aggctgcagt gattatcatt tgttcataaa tctttgtgaa gatctttggg
     3541 tactgcctta cattaaaatc tttttcaatt tgaccagtaa aagtggcatg ttagtaacat
     3601 tgtcattttc agtgttagat tatgtagtac taagtttatt ttattttatt tttgagacag
     3661 agtcttgcac tgtcgcccag gctggagtgc agtggcgcca tctcagctca ctgcaacctc
     3721 cacctcccag gttcaagcga ttcttctgcc tcagcctccc gagtagctgg gattacaggc
     3781 acccaccacg atgcccagct aattttttgt atttttagta gagacagggt ttcactatgt
     3841 tgtccaggct ggtctcgaac gcctgacctc atgatccacc tgcctcggcc tcccaaagtg
     3901 ttgggattac aggcatgagc caccctgccc gacctagtaa tacttttttt tttttttttt
     3961 tttaatgaac ttaaatgttt agaatggtaa gttcacggct ccctaaggag tgttcctttt
     4021 ggattgctct gtttggctcc ctccctgaaa tcctatagtc agccactggt cccctcagag
     4081 agttttacct ctgatctttg gggtgattct ttgttcatat ttatctgatt ggctttgttc
     4141 ttccaaaagt gtctgcacag gactgctaag agaacctagg caagtcattt aatttttctg
     4201 ggcttcagtt tactcattag cttcttttag ttcccagatg ctattactgg aaagaataac
     4261 tagtaatgga taaaaaccta cataaatatt tcctattttg ccatcaaagt gctgggttca
     4321 ttttggtgta tttggcatcc aagtacaaat taacagtttc ccaaaatcct gattctttga
     4381 cttttttatc ttgatgatgg aaaggaagga cacgtttact tgctttagtt tctttcccct
     4441 taactaccca cttgctgaga ggggtaggag cagggattgg ctttagagaa acaagataca
     4501 gtgtagatta gctaatgttt gcgcttaaca aaacttgtcc tgtttaactt acctgagggt
     4561 tctgcagcct accgcagtaa ttttagttct agctgttttc agatatattg ccttgtatct
     4621 tcgttctttc gtctcctatc ctttttagaa atttatcacc tgtttctctt tcagcctgac
     4681 ttacaaaatc taatttttgg cctaaaaatt tcccctagct tggtactagt ccttttattt
     4741 ctgcctgtga ttatatttta aaattaaact taaatgaatc taattcattg gatatataaa
     4801 aaaaaaagta agtggcttgc tttgcttact ctggttttcc atcctcattc ctggatataa
     4861 tcaagattgc agtaggctaa caatctaatg ctgaaaacaa gaatgaaaaa cataccatct
     4921 tttcaagtta ctttggaccc atagagagaa agtggattgg tacttaatac cttccctgaa
     4981 tttaacagaa ttgatgtgga ctgtacataa aatatgttga aaaataaaac tatttttttg
     5041 gctataa
//
