LOCUS       NM_152347               3957 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens EF-hand calcium binding domain 13 (EFCAB13),
            transcript variant A, coding, mRNA.
ACCESSION   NM_152347 XM_005257047
VERSION     NM_152347.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3957)
  AUTHORS   Willer,C.J., Schmidt,E.M., Sengupta,S., Peloso,G.M., Gustafsson,S.,
            Kanoni,S., Ganna,A., Chen,J., Buchkovich,M.L., Mora,S.,
            Beckmann,J.S., Bragg-Gresham,J.L., Chang,H.Y., Demirkan,A., Den
            Hertog,H.M., Do,R., Donnelly,L.A., Ehret,G.B., Esko,T.,
            Feitosa,M.F., Ferreira,T., Fischer,K., Fontanillas,P., Fraser,R.M.,
            Freitag,D.F., Gurdasani,D., Heikkila,K., Hypponen,E., Isaacs,A.,
            Jackson,A.U., Johansson,A., Johnson,T., Kaakinen,M., Kettunen,J.,
            Kleber,M.E., Li,X., Luan,J., Lyytikainen,L.P., Magnusson,P.K.E.,
            Mangino,M., Mihailov,E., Montasser,M.E., Muller-Nurasyid,M.,
            Nolte,I.M., O'Connell,J.R., Palmer,C.D., Perola,M., Petersen,A.K.,
            Sanna,S., Saxena,R., Service,S.K., Shah,S., Shungin,D., Sidore,C.,
            Song,C., Strawbridge,R.J., Surakka,I., Tanaka,T., Teslovich,T.M.,
            Thorleifsson,G., Van den Herik,E.G., Voight,B.F., Volcik,K.A.,
            Waite,L.L., Wong,A., Wu,Y., Zhang,W., Absher,D., Asiki,G.,
            Barroso,I., Been,L.F., Bolton,J.L., Bonnycastle,L.L., Brambilla,P.,
            Burnett,M.S., Cesana,G., Dimitriou,M., Doney,A.S.F., Doring,A.,
            Elliott,P., Epstein,S.E., Ingi Eyjolfsson,G., Gigante,B.,
            Goodarzi,M.O., Grallert,H., Gravito,M.L., Groves,C.J., Hallmans,G.,
            Hartikainen,A.L., Hayward,C., Hernandez,D., Hicks,A.A., Holm,H.,
            Hung,Y.J., Illig,T., Jones,M.R., Kaleebu,P., Kastelein,J.J.P.,
            Khaw,K.T., Kim,E., Klopp,N., Komulainen,P., Kumari,M.,
            Langenberg,C., Lehtimaki,T., Lin,S.Y., Lindstrom,J., Loos,R.J.F.,
            Mach,F., McArdle,W.L., Meisinger,C., Mitchell,B.D., Muller,G.,
            Nagaraja,R., Narisu,N., Nieminen,T.V.M., Nsubuga,R.N., Olafsson,I.,
            Ong,K.K., Palotie,A., Papamarkou,T., Pomilla,C., Pouta,A.,
            Rader,D.J., Reilly,M.P., Ridker,P.M., Rivadeneira,F., Rudan,I.,
            Ruokonen,A., Samani,N., Scharnagl,H., Seeley,J., Silander,K.,
            Stancakova,A., Stirrups,K., Swift,A.J., Tiret,L.,
            Uitterlinden,A.G., van Pelt,L.J., Vedantam,S., Wainwright,N.,
            Wijmenga,C., Wild,S.H., Willemsen,G., Wilsgaard,T., Wilson,J.F.,
            Young,E.H., Zhao,J.H., Adair,L.S., Arveiler,D., Assimes,T.L.,
            Bandinelli,S., Bennett,F., Bochud,M., Boehm,B.O., Boomsma,D.I.,
            Borecki,I.B., Bornstein,S.R., Bovet,P., Burnier,M., Campbell,H.,
            Chakravarti,A., Chambers,J.C., Chen,Y.I., Collins,F.S.,
            Cooper,R.S., Danesh,J., Dedoussis,G., de Faire,U., Feranil,A.B.,
            Ferrieres,J., Ferrucci,L., Freimer,N.B., Gieger,C., Groop,L.C.,
            Gudnason,V., Gyllensten,U., Hamsten,A., Harris,T.B., Hingorani,A.,
            Hirschhorn,J.N., Hofman,A., Hovingh,G.K., Hsiung,C.A.,
            Humphries,S.E., Hunt,S.C., Hveem,K., Iribarren,C., Jarvelin,M.R.,
            Jula,A., Kahonen,M., Kaprio,J., Kesaniemi,A., Kivimaki,M.,
            Kooner,J.S., Koudstaal,P.J., Krauss,R.M., Kuh,D., Kuusisto,J.,
            Kyvik,K.O., Laakso,M., Lakka,T.A., Lind,L., Lindgren,C.M.,
            Martin,N.G., Marz,W., McCarthy,M.I., McKenzie,C.A., Meneton,P.,
            Metspalu,A., Moilanen,L., Morris,A.D., Munroe,P.B., Njolstad,I.,
            Pedersen,N.L., Power,C., Pramstaller,P.P., Price,J.F., Psaty,B.M.,
            Quertermous,T., Rauramaa,R., Saleheen,D., Salomaa,V.,
            Sanghera,D.K., Saramies,J., Schwarz,P.E.H., Sheu,W.H.,
            Shuldiner,A.R., Siegbahn,A., Spector,T.D., Stefansson,K.,
            Strachan,D.P., Tayo,B.O., Tremoli,E., Tuomilehto,J., Uusitupa,M.,
            van Duijn,C.M., Vollenweider,P., Wallentin,L., Wareham,N.J.,
            Whitfield,J.B., Wolffenbuttel,B.H.R., Ordovas,J.M., Boerwinkle,E.,
            Palmer,C.N.A., Thorsteinsdottir,U., Chasman,D.I., Rotter,J.I.,
            Franks,P.W., Ripatti,S., Cupples,L.A., Sandhu,M.S., Rich,S.S.,
            Boehnke,M., Deloukas,P., Kathiresan,S., Mohlke,K.L., Ingelsson,E.
            and Abecasis,G.R.
  CONSRTM   Global Lipids Genetics Consortium
  TITLE     Discovery and refinement of loci associated with lipid levels
  JOURNAL   Nat Genet 45 (11), 1274-1283 (2013)
   PUBMED   24097068
REFERENCE   2  (bases 1 to 3957)
  AUTHORS   Teslovich,T.M., Musunuru,K., Smith,A.V., Edmondson,A.C.,
            Stylianou,I.M., Koseki,M., Pirruccello,J.P., Ripatti,S.,
            Chasman,D.I., Willer,C.J., Johansen,C.T., Fouchier,S.W., Isaacs,A.,
            Peloso,G.M., Barbalic,M., Ricketts,S.L., Bis,J.C., Aulchenko,Y.S.,
            Thorleifsson,G., Feitosa,M.F., Chambers,J., Orho-Melander,M.,
            Melander,O., Johnson,T., Li,X., Guo,X., Li,M., Shin Cho,Y., Jin
            Go,M., Jin Kim,Y., Lee,J.Y., Park,T., Kim,K., Sim,X., Twee-Hee
            Ong,R., Croteau-Chonka,D.C., Lange,L.A., Smith,J.D., Song,K., Hua
            Zhao,J., Yuan,X., Luan,J., Lamina,C., Ziegler,A., Zhang,W.,
            Zee,R.Y., Wright,A.F., Witteman,J.C., Wilson,J.F., Willemsen,G.,
            Wichmann,H.E., Whitfield,J.B., Waterworth,D.M., Wareham,N.J.,
            Waeber,G., Vollenweider,P., Voight,B.F., Vitart,V.,
            Uitterlinden,A.G., Uda,M., Tuomilehto,J., Thompson,J.R., Tanaka,T.,
            Surakka,I., Stringham,H.M., Spector,T.D., Soranzo,N., Smit,J.H.,
            Sinisalo,J., Silander,K., Sijbrands,E.J., Scuteri,A., Scott,J.,
            Schlessinger,D., Sanna,S., Salomaa,V., Saharinen,J., Sabatti,C.,
            Ruokonen,A., Rudan,I., Rose,L.M., Roberts,R., Rieder,M.,
            Psaty,B.M., Pramstaller,P.P., Pichler,I., Perola,M., Penninx,B.W.,
            Pedersen,N.L., Pattaro,C., Parker,A.N., Pare,G., Oostra,B.A.,
            O'Donnell,C.J., Nieminen,M.S., Nickerson,D.A., Montgomery,G.W.,
            Meitinger,T., McPherson,R., McCarthy,M.I., McArdle,W., Masson,D.,
            Martin,N.G., Marroni,F., Mangino,M., Magnusson,P.K., Lucas,G.,
            Luben,R., Loos,R.J., Lokki,M.L., Lettre,G., Langenberg,C.,
            Launer,L.J., Lakatta,E.G., Laaksonen,R., Kyvik,K.O., Kronenberg,F.,
            Konig,I.R., Khaw,K.T., Kaprio,J., Kaplan,L.M., Johansson,A.,
            Jarvelin,M.R., Janssens,A.C., Ingelsson,E., Igl,W., Kees
            Hovingh,G., Hottenga,J.J., Hofman,A., Hicks,A.A., Hengstenberg,C.,
            Heid,I.M., Hayward,C., Havulinna,A.S., Hastie,N.D., Harris,T.B.,
            Haritunians,T., Hall,A.S., Gyllensten,U., Guiducci,C., Groop,L.C.,
            Gonzalez,E., Gieger,C., Freimer,N.B., Ferrucci,L., Erdmann,J.,
            Elliott,P., Ejebe,K.G., Doring,A., Dominiczak,A.F., Demissie,S.,
            Deloukas,P., de Geus,E.J., de Faire,U., Crawford,G., Collins,F.S.,
            Chen,Y.D., Caulfield,M.J., Campbell,H., Burtt,N.P.,
            Bonnycastle,L.L., Boomsma,D.I., Boekholdt,S.M., Bergman,R.N.,
            Barroso,I., Bandinelli,S., Ballantyne,C.M., Assimes,T.L.,
            Quertermous,T., Altshuler,D., Seielstad,M., Wong,T.Y., Tai,E.S.,
            Feranil,A.B., Kuzawa,C.W., Adair,L.S., Taylor,H.A. Jr.,
            Borecki,I.B., Gabriel,S.B., Wilson,J.G., Holm,H.,
            Thorsteinsdottir,U., Gudnason,V., Krauss,R.M., Mohlke,K.L.,
            Ordovas,J.M., Munroe,P.B., Kooner,J.S., Tall,A.R., Hegele,R.A.,
            Kastelein,J.J., Schadt,E.E., Rotter,J.I., Boerwinkle,E.,
            Strachan,D.P., Mooser,V., Stefansson,K., Reilly,M.P., Samani,N.J.,
            Schunkert,H., Cupples,L.A., Sandhu,M.S., Ridker,P.M., Rader,D.J.,
            van Duijn,C.M., Peltonen,L., Abecasis,G.R., Boehnke,M. and
            Kathiresan,S.
  TITLE     Biological, clinical and population relevance of 95 loci for blood
            lipids
  JOURNAL   Nature 466 (7307), 707-713 (2010)
   PUBMED   20686565
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC068234.8, BX471329.1, BC036407.2 and AC040934.15.
            
            On Nov 22, 2018 this sequence version replaced NM_152347.4.
            
            Transcript Variant: This variant (A) represents the longer
            transcript and encodes the longer isoform (A).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC036407.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2145313
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000331493.7/ ENSP00000332111.2
            RefSeq Select criteria :: based on longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 AC068234.8         66482-66487         c
            7-29                BX471329.1         3-25
            30-2285             BC036407.2         4-2259
            2286-2286           AC040934.15        69983-69983
            2287-3957           BC036407.2         2261-3931
FEATURES             Location/Qualifiers
     source          1..3957
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.32"
     gene            1..3957
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /note="EF-hand calcium binding domain 13"
                     /db_xref="GeneID:124989"
                     /db_xref="HGNC:HGNC:26864"
     exon            1..120
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            121..190
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            191..352
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            353..467
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     CDS             438..3359
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /note="isoform A is encoded by transcript variant A,
                     coding; EF-hand domain-containing protein C17orf57;
                     EF-hand calcium-binding domain-containing protein 13"
                     /codon_start=1
                     /product="EF-hand calcium-binding domain-containing
                     protein 13 isoform A"
                     /protein_id="NP_689560.3"
                     /db_xref="CCDS:CCDS11512.1"
                     /db_xref="GeneID:124989"
                     /db_xref="HGNC:HGNC:26864"
                     /translation="METKVHLFCQAEENIDLLDDGSNSFATDLSSGTINHKKYIKFSK
                     TIEKEISPEIRSLSPEYKKIFETSIIFCGEEKSSDFSGEKKVGRKSLQVQQHSKRTEI
                     IPPFLKLSKEKVTRKENSLCKLPNQYSVHKTSSPLCTSSAITREKEMLSNLYMTLYDE
                     VTHGYLHSKELSALHKACKIFSKIRSGKIYVNDLPVILCILRISISDLEMRQALKTVD
                     IDAFQDALKIFCRIKGGRVSTDDVFAVLDSMGIPINREILEEVTKHTYIDSNHMVDIG
                     DIIFTLNELQEQYEDVSITEGSPLNEITSDRKLSSVAGCYLKYKKKNSLSSKLPEPSI
                     SKKLNKKSNQYYSKIMENDDLESKRPKNTWQIRKFLGGVGSSNVGVQEPYSKNGINFK
                     KHSEKGEIHDSKSKPQSLKSSTSLSKSLDKSDISSIPKLQKPAVRKHSSLQKQVSSTE
                     KTAISTLENFCEAISKLQENYIAAEELQSILPSTGINLLDEEFQKIVTDTSRNENGMV
                     ELDDFVNALAKERSFPECNALPGVIKAIDKIKDKNVDYEDLNTCLQNFGIYLSKPEFK
                     KITELTEAGETKKVNFKEFIDTMMSNTECFSEKLVLPDAIETLDDLRKETMSVSDLWN
                     TLSSLNSNLKKDEFLAALELVTVDEGDKVQFEEFAKVVRNMRDAARLEELQEVVLAAD
                     LLEGDMIAGKNLEDFLRNVGIKSPKEEVEKILQSDFVSEDNMVNIKDCMRALRDTQKF
                     SNYIDFRKEASNLKLPKVNEIKEAANILSHVDNGKIGIPDLEHALKCLNVNLTEEDFN
                     EALNCCNVSDNMEVDLKDFLMKMKESPHFQKSKATQILLATTQILQNDLVDVSDLKTL
                     LMDKDLHTANAILTVMLRHVPEHESGKVSIQEFMTKLSDILTIPKAAGKFYLICTYCP
                     DLERQAVVYMLKTIQDSIVKAQVSKKQYNMNIKQHKISLHNFCLNSKANIAKLNPNSK
                     F"
     exon            468..628
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            629..740
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            741..871
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            872..954
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            955..1098
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..1242
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            1243..1314
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            1315..1809
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..1947
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            1948..2019
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2020..2163
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2164..2238
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2239..2382
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2383..2454
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2455..2598
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2599..2670
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2671..2715
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2716..2859
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2860..2931
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2932..3075
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            3076..3957
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3930..3935
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /note="hexamer: AATAAA"
     polyA_site      3957
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /note="major polyA site"
ORIGIN      
        1 gcggcgcggg atcctgggaa ggctgcagag ctagagcagc gccgcccgag gggcggcagg
       61 ggctgaccac agagagcgcg ggggcctcca gccgagagga agggagggca gctcgggccg
      121 aagtcgttgg cttcgtaaga gcagggtcta tgggaagcct cctcagcgtg ggttcttgga
      181 agaggtggag tttggagagg cttatgcggt acctgattca tccagcaaat taagacctgc
      241 caactttttg ataatctcgt caataaatta cagaacaatt gttcctttca agatttattc
      301 aaaacgtgtc aactctgctt aattaagcac tttgatgatt taagaaatct tggaaatcct
      361 tttgtactat tgctcattca tacttgttca tcaaagcctg gagtccttaa ggacagaatt
      421 tacctctaaa cagaaagatg gaaactaaag tacatttatt ctgccaggca gaggaaaata
      481 ttgacttatt agatgatggc tctaattctt ttgcaactga cttgtcatca ggaactatta
      541 accacaagaa atacatcaag ttttctaaaa caatagagaa ggaaatttca ccggaaatta
      601 ggagtttgag cccagaatat aaaaaaatat ttgaaacatc aataatcttt tgtggagaag
      661 aaaagtcctc tgatttttca ggagaaaaaa aagttgggag aaagagttta caagtacaac
      721 agcacagtaa aagaactgag attatccctc cttttctgaa gctgtcaaag gagaaggtga
      781 caaggaaaga aaactcttta tgcaagttgc cgaatcagta cagcgttcac aagacttcat
      841 cacctctttg tacatcttct gcaattactc gggaaaagga aatgctgtct aacctctaca
      901 tgacattata tgatgaagta acccatggat atttacactc aaaagaatta agtgcacttc
      961 ataaagcctg taaaattttt agtaaaattc gaagtggtaa gatttatgtg aatgatcttc
     1021 cagtgatcct ttgcatcttg agaatttcta taagtgattt agaaatgcga caggcactaa
     1081 agactgttga tattgatgca ttccaggatg ccttgaagat tttctgtagg ataaaaggtg
     1141 gtcgagtttc aactgatgac gtgtttgctg ttttggatag catgggtatc cctataaacc
     1201 gtgaaatttt agaagaagtg acaaaacata cctatattga cagtaaccac atggtggata
     1261 ttggggatat tatatttact ttgaatgagc tacaggaaca gtatgaggat gtttcaatta
     1321 cagaaggatc acctttgaat gaaattactt cagacagaaa gttatcaagt gtagcaggat
     1381 gctatctaaa atataagaag aaaaatagtt tgtcttccaa actccctgaa ccttcaatat
     1441 ccaaaaagtt aaataaaaaa agcaaccaat attatagcaa aattatggag aatgatgacc
     1501 ttgaatctaa aagaccaaaa aatacttggc aaataagaaa atttctgggt ggggttggca
     1561 gcagtaatgt aggagtccaa gaaccatatt caaagaatgg cataaacttt aaaaaacatt
     1621 cagagaaggg tgaaattcat gactcaaagt ctaaaccaca aagcttgaag agtagtacaa
     1681 gcctcagtaa gtctctggat aaaagtgata tttctagtat cccaaaactt cagaagccag
     1741 ctgtaagaaa gcattccagt ctccaaaaac aggtttcgtc tacggaaaaa actgcaatta
     1801 gtactctgga aaacttctgt gaagctatca gtaaacttca agaaaattac attgcagcag
     1861 aagaacttca gtctattttg ccttcaacag gaattaattt attagatgaa gaattccaga
     1921 agattgtgac agacactagt agaaatgaga atggaatggt ggagttagat gactttgtaa
     1981 atgctctcgc caaggagcga agttttcctg aatgcaatgc gttgcctggt gtcattaaag
     2041 ccattgataa aattaaagat aaaaatgtgg attatgagga tctaaatact tgtcttcaaa
     2101 attttggtat ttacctttct aagccagaat ttaagaagat cacagaactg actgaagctg
     2161 gtgaaacaaa aaaagtgaat tttaaagaat tcattgatac tatgatgagc aacacggaat
     2221 gcttctctga aaaattagta ttgcctgatg ctattgaaac cctcgacgat ctcagaaagg
     2281 agacgatgag tgtttctgac ctgtggaata ctctgtctag tttgaatagt aatttaaaaa
     2341 aggatgaatt tctagctgca ttggaactag tgacagttga tgaaggtgac aaagtacaat
     2401 ttgaagaatt tgcaaaagta gtaaggaata tgcgtgatgc tgccaggtta gaagagttac
     2461 aggaagttgt cttagctgct gatttgctgg aaggtgacat gatagctggg aagaacttgg
     2521 aagactttct aagaaatgtt gggattaagt cacctaaaga agaggtagag aaaattcttc
     2581 aatcagattt tgtttctgaa gataacatgg tgaacattaa agactgtatg agggctttga
     2641 gggacaccca gaaattttcc aattatattg atttcaggaa agaggcttca aatctaaaat
     2701 taccaaaggt aaacgagatt aaagaagctg ctaacatctt gtcacatgtc gataatggca
     2761 agattggtat acctgatttg gagcatgcct tgaaatgttt gaatgttaat ttaactgagg
     2821 aggacttcaa tgaagccctt aactgttgta acgtcagtga taatatggag gtggatttaa
     2881 aagatttctt aatgaaaatg aaagaaagtc cacatttcca aaagtccaag gctacacaga
     2941 tactcttagc tactacccaa attctccaga atgatctagt tgatgtctct gacctcaaga
     3001 cattattgat ggacaaggac cttcatacag ctaatgctat acttactgta atgttaagac
     3061 atgtacctga acatgaaagt ggcaaggtta gcattcaaga atttatgact aaattatccg
     3121 atatattgac aattcctaaa gctgcaggta agttttattt aatatgtact tattgcccag
     3181 atctagaaag gcaagcagtg gtttacatgt taaaaacaat acaggattcg atagttaaag
     3241 cacaggtaag taagaagcaa tacaatatga atataaaaca acacaagatt agtttacata
     3301 acttctgttt gaattctaag gcaaatattg ctaagcttaa cccaaactca aaattttagg
     3361 tagtcttact tgatagtgct agaaaattac tagattatat attattcagt atgcatattt
     3421 gacttctgaa attattagaa aataattttt aaaacttttg acaaatccag tagaattttt
     3481 atcactatct gttatgttct catgtatctt cagcgactct cttgatcaca ctttttaaac
     3541 attcatgctt tttgaggtat aatgtacata tggcaaaatt cactcttttt aggtatacag
     3601 ttctttggat tcttaaaaat aatgtaatgt aacccttact atacacaaca tatagactat
     3661 attatccccc agaagtctct tatgcccttt tggtaatcca tttcttcctc taccctgagc
     3721 ccctggcaac tactgattca ttctttgtcc ctctagtttt gccttttgtg gaatatcatg
     3781 taaatgatta aatatgaagt ggtttgagtt tggcagtcat tgcatgcata taccttgaat
     3841 ttactttgtt tatactctca tttatactac caaccctccc tagaaaaaat ggattctgat
     3901 tggttctggt tgcagtatta caaattccaa ataaagcttt atttgaggac ccccaaa
//
