LOCUS       NM_001355526             737 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens EF-hand calcium binding domain 10 (EFCAB10),
            transcript variant 1, mRNA.
ACCESSION   NM_001355526 NR_027068 XM_001719448 XM_001719450 XM_001723041
            XM_001723043 XM_001725526 XM_001725527 XM_001725807 XM_001725809
VERSION     NM_001355526.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 737)
  AUTHORS   Winham,S.J., Cuellar-Barboza,A.B., Oliveros,A., McElroy,S.L.,
            Crow,S., Colby,C., Choi,D.S., Chauhan,M., Frye,M. and
            Biernacka,J.M.
  TITLE     Genome-wide association study of bipolar disorder accounting for
            effect of body mass index identifies a new risk allele in TCF7L2
  JOURNAL   Mol Psychiatry 19 (9), 1010-1016 (2014)
   PUBMED   24322204
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC105284.1 and BE502251.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001355526.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC105284.1, SRR5189667.362273.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2161674 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000480514.6/ ENSP00000418678.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-725               BC105284.1         12-736
            726-737             BE502251.1         17-28               c
FEATURES             Location/Qualifiers
     source          1..737
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q22.3"
     gene            1..737
                     /gene="EFCAB10"
                     /note="EF-hand calcium binding domain 10"
                     /db_xref="GeneID:100130771"
                     /db_xref="HGNC:HGNC:34531"
     exon            1..136
                     /gene="EFCAB10"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..414
                     /gene="EFCAB10"
                     /note="isoform 1 is encoded by transcript variant 1;
                     EF-hand domain-containing protein; eF-hand calcium-binding
                     domain-containing protein 10"
                     /codon_start=1
                     /product="EF-hand calcium-binding domain-containing
                     protein 10 isoform 1"
                     /protein_id="NP_001342455.1"
                     /db_xref="CCDS:CCDS87537.1"
                     /db_xref="GeneID:100130771"
                     /db_xref="HGNC:HGNC:34531"
                     /translation="METSSRELQAAEYLEKHQIKEVVSYLTSALLFFRPEKPKEYLIS
                     LLERLRIAKVTGVAFPFFMDNSNIVAMFEMMDSSGRGTISFVQYKEALKTLGLCTEDE
                     DLQDDGHKITLDKFKEEVNKRMKEI"
     exon            137..301
                     /gene="EFCAB10"
                     /inference="alignment:Splign:2.1.0"
     exon            302..389
                     /gene="EFCAB10"
                     /inference="alignment:Splign:2.1.0"
     exon            390..413
                     /gene="EFCAB10"
                     /inference="alignment:Splign:2.1.0"
     exon            414..737
                     /gene="EFCAB10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      698..703
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EFCAB10"
                     /note="hexamer: AATATA"
     polyA_site      728
                     /gene="EFCAB10"
     regulatory      732..737
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EFCAB10"
                     /note="hexamer: AATAAA"
     polyA_site      737
                     /gene="EFCAB10"
                     /note="major polyA site"
ORIGIN      
        1 agtcgcctag caacagcggg acgcggagcg atggagacca gcagcaggga gctccaagcc
       61 gcggagtatt tggaaaagca tcagatcaag gaggtggtta gctacctcac cagcgccctc
      121 cttttctttc ggccggaaaa accaaaagaa tatttaatat ctctattgga acgactgaga
      181 attgcaaaag taacaggcgt ggcgtttcct ttctttatgg ataactctaa cattgtggct
      241 atgtttgaga tgatggactc ctcaggcaga ggcaccatat catttgtgca gtataaagaa
      301 gccctaaaaa ccctgggtct atgcactgaa gatgaagatt tacaagatga tggacataaa
      361 ataactttgg ataaattcaa ggaggaagtg aacaagagga tgaaggaaat atgatgtata
      421 catccagctt ctctacaagc atttgccaga aaattttaaa taaggagaaa caaagctgct
      481 gctccaactg aagtaaatgg tctcgtaacg tcagcagcaa cgggcaagcc gaactggaca
      541 gggacatcac tgcctgctct gactgagatg gcaaggacaa ccatctggaa aaaacacatt
      601 tttaccaaaa aattttcatc agtttctatt tttcaagttt ttaaatcatt ttaaatttga
      661 ggaagtgttc tgtcctaggg cattttggat aagaaaaaat atacagccta acattaaaag
      721 ctctatcaga aaataaa
//
