LOCUS       NM_001271785            4314 bp    mRNA    linear   PRI 21-SEP-2024
DEFINITION  Homo sapiens dynein cytoplasmic 1 intermediate chain 2 (DYNC1I2),
            transcript variant 2, mRNA.
ACCESSION   NM_001271785
VERSION     NM_001271785.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4314)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   2  (bases 1 to 4314)
  AUTHORS   Habu,T. and Kim,J.
  TITLE     Dynein intermediate chain 2c (DNCI2c) complex is essential for
            exiting Mad2-dependent spindle assembly checkpoint
  JOURNAL   Biochim Biophys Acta Mol Cell Res 1868 (12), 119120 (2021)
   PUBMED   34400173
  REMARK    GeneRIF: Dynein intermediate chain 2c (DNCI2c) complex is essential
            for exiting Mad2-dependent spindle assembly checkpoint.
REFERENCE   3  (bases 1 to 4314)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (bases 1 to 4314)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 4314)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4314)
  AUTHORS   Palmer,K.J., Hughes,H. and Stephens,D.J.
  TITLE     Specificity of cytoplasmic dynein subunits in discrete
            membrane-trafficking steps
  JOURNAL   Mol Biol Cell 20 (12), 2885-2899 (2009)
   PUBMED   19386764
REFERENCE   7  (bases 1 to 4314)
  AUTHORS   Pfister,K.K., Fisher,E.M., Gibbons,I.R., Hays,T.S., Holzbaur,E.L.,
            McIntosh,J.R., Porter,M.E., Schroer,T.A., Vaughan,K.T.,
            Witman,G.B., King,S.M. and Vallee,R.B.
  TITLE     Cytoplasmic dynein nomenclature
  JOURNAL   J Cell Biol 171 (3), 411-413 (2005)
   PUBMED   16260502
REFERENCE   8  (bases 1 to 4314)
  AUTHORS   Davies,T.H., Ning,Y.M. and Sanchez,E.R.
  TITLE     A new first step in activation of steroid receptors:
            hormone-induced switching of FKBP51 and FKBP52 immunophilins
  JOURNAL   J Biol Chem 277 (7), 4597-4600 (2002)
   PUBMED   11751894
REFERENCE   9  (bases 1 to 4314)
  AUTHORS   Crackower,M.A., Sinasac,D.S., Xia,J., Motoyama,J., Prochazka,M.,
            Rommens,J.M., Scherer,S.W. and Tsui,L.C.
  TITLE     Cloning and characterization of two cytoplasmic dynein intermediate
            chain genes in mouse and human
  JOURNAL   Genomics 55 (3), 257-267 (1999)
   PUBMED   10049579
REFERENCE   10 (bases 1 to 4314)
  AUTHORS   Vaughan,K.T. and Vallee,R.B.
  TITLE     Cytoplasmic dynein binds dynactin through a direct interaction
            between the intermediate chains and p150Glued
  JOURNAL   J Cell Biol 131 (6 Pt 1), 1507-1516 (1995)
   PUBMED   8522607
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK096579.1, AK055491.1 and
            AC068039.6.
            
            On Jun 3, 2019 this sequence version replaced NM_001271785.1.
            
            Summary: This gene encodes a member of the dynein intermediate
            chain family. The encoded protein is a non-catalytic component of
            the cytoplasmic dynein 1 complex, which acts as a retrograde
            microtubule motor to transport organelles and vesicles. A
            pseudogene of this gene is located on chromosome 10. Alternative
            splicing results in multiple transcript variants. [provided by
            RefSeq, Nov 2012].
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803617.224175.1,
                                           SRR1803611.130167.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145743, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-232               AK096579.1         1-232
            233-633             AK055491.1         270-670
            634-2234            AK096579.1         635-2235
            2235-4314           AC068039.6         43438-45517
FEATURES             Location/Qualifiers
     source          1..4314
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q31.1"
     gene            1..4314
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /note="dynein cytoplasmic 1 intermediate chain 2"
                     /db_xref="GeneID:1781"
                     /db_xref="HGNC:HGNC:2964"
                     /db_xref="MIM:603331"
     exon            1..119
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            120..236
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..2045
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /note="isoform 1 is encoded by transcript variant 2;
                     dynein, cytoplasmic, intermediate polypeptide 2; DH IC-2;
                     dynein intermediate chain 2, cytosolic; testis tissue
                     sperm-binding protein Li 66n"
                     /codon_start=1
                     /product="cytoplasmic dynein 1 intermediate chain 2
                     isoform 1"
                     /protein_id="NP_001258714.1"
                     /db_xref="CCDS:CCDS46450.1"
                     /db_xref="GeneID:1781"
                     /db_xref="HGNC:HGNC:2964"
                     /db_xref="MIM:603331"
                     /translation="MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAV
                     APVQEESDLEKKRREAEALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQ
                     DSGDGAVGSRTLHWDTDPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKET
                     QTPVMAQPKEDEEEDDDVVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILH
                     SEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERW
                     SKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSA
                     VMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGT
                     QNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVG
                     SEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKL
                     WTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASIS
                     VEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINAN
                     RADAEEEAATRIPA"
     exon            237..354
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            355..372
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            373..463
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            464..523
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            524..639
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            640..735
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            736..898
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            899..998
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1124
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            1125..1271
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            1272..1385
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1519
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            1520..1664
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            1665..1805
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            1806..1931
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     exon            1932..4314
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2546..2551
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /note="hexamer: AATAAA"
     regulatory      2552..2557
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /note="hexamer: AACAAA"
     polyA_site      2567
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /note="major polyA site"
     polyA_site      2576
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /note="major polyA site"
     regulatory      3837..3842
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /note="hexamer: AATAAA"
     polyA_site      3859
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
     regulatory      4294..4299
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
                     /note="hexamer: AATAAA"
     polyA_site      4314
                     /gene="DYNC1I2"
                     /gene_synonym="DIC74; DNCI2; IC2; NEDMIBA"
ORIGIN      
        1 gtgtgctttg gaaagccgcg gagctggtgg tggctacagt tggtgttggg ggcttaggcg
       61 agggacgtta ccgggaagtt gcaggcggga ggactcttcc ccatccagtc acctgacagg
      121 tcacaaacat gtcagacaaa agtgaattaa aggctgagtt ggaacgtaag aagcagcgac
      181 tggcccaaat cagagaggaa aagaagagaa aagaagaaga aaggaaaaaa aaagaaacag
      241 accagaagaa ggaagctgtt gctcctgtgc aagaagaatc agatcttgaa aaaaaaagga
      301 gagaagctga agcattgctt caaagcatgg ggctaactcc agaatccccc attgtttttt
      361 ctgaatactg ggtccctcct cctatgtctc catcctccaa atctgtgagc actccaagtg
      421 aagctggaag ccaagactct ggagatggcg ccgtgggatc taggacgctg cattgggata
      481 cagatccatc agttcttcag cttcactcag attccgattt gggacgagga cctattaaac
      541 ttggaatggc taaaatcacg caagtcgact ttcctcctcg agaaattgtc acgtatacaa
      601 aggaaactca gactccagtt atggctcaac ccaaagaaga tgaagaggaa gatgatgatg
      661 tagtggctcc taaaccacct attgaacctg aagaagagaa aactttaaag aaagatgagg
      721 aaaatgatag taaagctccc cctcatgagc tgactgaaga agaaaagcaa caaatcttgc
      781 actctgagga atttttaagt ttctttgacc attctacaag aattgtagaa agagctcttt
      841 ctgagcagat taacatcttc tttgactata gtgggagaga tttggaagac aaagaaggag
      901 agattcaagc aggtgctaaa ctgtcattaa atcgacaatt ttttgacgaa cgttggtcaa
      961 agcatcgggt ggttagttgt ttggattggt catctcagta tccggagtta ctcgtggctt
     1021 cctataacaa caatgaagat gcccctcatg agcctgatgg tgtggccctt gtatggaata
     1081 tgaaatacaa aaaaactacc ccagagtatg tgtttcactg ccagtcagct gtgatgtctg
     1141 ccacatttgc aaaatttcat ccaaatcttg ttgttggtgg tacatattca ggccaaattg
     1201 tgctttggga taaccgtagc aataaaagaa ctccagtgca aagaactcca ctgtcagcag
     1261 ctgcacacac acaccctgta tattgtgtaa atgttgttgg aacacaaaat gctcacaatc
     1321 tgattagcat ctctactgat ggaaaaattt gttcatggag tctggacatg ctttcccatc
     1381 cacaggatag catggagttg gttcataaac agtcaaaagc agtagctgtg acatctatgt
     1441 ccttccctgt tggagatgtc aacaactttg ttgttgggag tgaagaaggt tctgtgtaca
     1501 cagcatgccg ccatggcagc aaagctggaa tcagtgagat gtttgagggg catcaaggac
     1561 caatcactgg catccattgt catgcagctg ttggagcagt agacttctca catctttttg
     1621 tcacttcatc gtttgactgg acagtaaagc tttggacaac taagaataac aagcctttgt
     1681 attcatttga agataatgca gactatgttt atgatgttat gtggtcacct acccacccag
     1741 ccctgtttgc ctgtgtggat ggcatgggga gattggattt gtggaatctc aataatgaca
     1801 cagaggtacc aactgccagc atttctgtgg agggtaatcc tgctcttaat cgtgtgagat
     1861 ggacccattc tggcagagag attgctgtgg gtgattctga aggacagatt gttatatacg
     1921 atgtgggaga gcagattgct gttccccgca atgatgaatg ggcacggttt ggccgaacac
     1981 ttgcagaaat taatgcaaac cgagctgatg cagaggagga agcagctacc cgaatacctg
     2041 cttagttcct gaaaagggga gtgtaactag tggatttggg aaaggttctt aagtagatcc
     2101 tgagactatt tgcatgcttc tgtctaaatg ataattaaaa ggaaatttca tggattaaac
     2161 catgggttta atgcagcaag gaaacttaca atgtcccttt atatataaca tgcatcttgt
     2221 tttggatttg tgtcattttt taatatagct gattgacttc acagaaagca gcttttttga
     2281 attctaatac ataggtgtat atttggtatt agttattttg agttcttttc aacttataac
     2341 actgtataca gttatttcta aagcacagat gaaataagtt ctgcatattt ttaaataatc
     2401 acagttccct gttatacaga taatgttctc actacccata atatgtagga acattgtttc
     2461 tccttagccg tagtatgcat acacctatcc atgttcattc tgacatcctt tgttgtcttt
     2521 ataattcatg tggtagttac ctataaataa aaacaaatat gcgttaactt ttcaaatttt
     2581 catttttact ccttacaact tgaatttttc catcttttat aaaatatatt ttttccatat
     2641 ctttctttaa gctcctgctg tgagcagcca tctcaaatcc tatagagctg tgtaccctaa
     2701 atataccatg tggtatatac tatagatctc ccagtgcatt atgaattgat gtctagataa
     2761 tctgttggtg aaaaaatttc ccctaggtta acttttgctt tactacttta tattctttcc
     2821 atctaagaca tatttccttt aaaggataaa tagaaagctg cctataattt tcactgatta
     2881 agaactatgt atgtgacctc actgagagta aaatctttga gagaaattga tttcatgatt
     2941 tcagtagcca taaaggcaaa gtgctcaaat ggacccatac tttggcatta aaatctacat
     3001 cttgagatct gttgccacag cattgtctac aagtccgaaa ggtaggtgac aaatatctaa
     3061 gaatcagtat tgaaatcagt gaatttcagg aatagaggaa aggactatga tcagatcttg
     3121 attttatcta ctttaaattg tctatttatt tgatcccaac cttttgtact tctgaagtgt
     3181 aactgtcttt tattcaacag aacatgaact aggaagagag attagaaaac agaatgtgaa
     3241 catttttctt ttaataattg taacaaagat ttgttgggag agaaatttcc aaataatgag
     3301 tagtgtatag tgtaaggaat aattgacctg gaattattgg ccccaaactc tgattcttgc
     3361 tgaagcatct atgagaagtg tgattttagc caagtctgtg ccgcattctt tatatgtagg
     3421 aattaagttt tgatttaatg atttctgaat tttctttcag ctctactcaa ttaaggggta
     3481 tcagtatgtg aaatggaata tagaaaagta ggcaattctt tacttttcta tattcagttt
     3541 cataaattaa taccccataa ttgcccatta tataccaaag acaatatctc aagttatctc
     3601 attgtagcag tgtctgtgag tcaaaacttc aattttagta gagtcacact ttctttatat
     3661 agaaaaattc atgtactcac tactcatgta gttactgtat ctttaccttc agtttgtaaa
     3721 aatgactaaa agtagggaaa acaagtgtta aaacataatg gataagaaaa ggttggaaat
     3781 catatggcaa atcacatgtt cctcagcctc aaggtgtgtt tagttgtgaa agaaagaata
     3841 aaattgttta aatatttcac tttttgggaa tgacttctcc cctactcccc cagaaaatgc
     3901 gatgtatacc tttgcccatt caactttagt ccatattttt aggaacacac aaatttactt
     3961 taaggaatta cctttaaagt tgactatata atagcaaaag agaaagtatt gagactgtca
     4021 gtgttgataa agcttctagc aagattaggt tgactagaag tgcatcacag ttctttatac
     4081 ttttagaact aaaagcctta taattttgaa aaatatccag ttacagaaat tgtaccttat
     4141 cagttatact ttttttctga gtaagaaaac aagctatagc tttctggtta atttcttatt
     4201 tttcgttgtt tggtttttgt ctttttgagt ggaacgttaa agtttattac cttcatgtta
     4261 aggaatatcc agcttcacag acaattaact tgcaataaat ctctgaaata atca
//
