LOCUS       NM_080664               2713 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens D-aminoacyl-tRNA deacylase 2 (DTD2), mRNA.
ACCESSION   NM_080664
VERSION     NM_080664.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2713)
  AUTHORS   Kuncha,S.K., Mazeed,M., Singh,R., Kattula,B., Routh,S.B. and
            Sankaranarayanan,R.
  TITLE     A chiral selectivity relaxed paralog of DTD for proofreading tRNA
            mischarging in Animalia
  JOURNAL   Nat Commun 9 (1), 511 (2018)
   PUBMED   29410408
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2713)
  AUTHORS   Havugimana,P.C., Hart,G.T., Nepusz,T., Yang,H., Turinsky,A.L.,
            Li,Z., Wang,P.I., Boutz,D.R., Fong,V., Phanse,S., Babu,M.,
            Craig,S.A., Hu,P., Wan,C., Vlasblom,J., Dar,V.U., Bezginov,A.,
            Clark,G.W., Wu,G.C., Wodak,S.J., Tillier,E.R., Paccanaro,A.,
            Marcotte,E.M. and Emili,A.
  TITLE     A census of human soluble protein complexes
  JOURNAL   Cell 150 (5), 1068-1081 (2012)
   PUBMED   22939629
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL163973.1, BI553940.1, AK055367.1, AL139353.3 and BU675173.1.
            
            On Nov 22, 2018 this sequence version replaced NM_080664.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.971230.1, AK055367.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2467146, SAMN03267755
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000310850.9/ ENSP00000312224.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                AL163973.1         7094-7125           c
            33-45               BI553940.1         9-21
            46-1162             AK055367.1         1-1117
            1163-2416           AL139353.3         163544-164797       c
            2417-2713           BU675173.1         16-312              c
FEATURES             Location/Qualifiers
     source          1..2713
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q12"
     gene            1..2713
                     /gene="DTD2"
                     /gene_synonym="ATD; C14orf126"
                     /note="D-aminoacyl-tRNA deacylase 2"
                     /db_xref="GeneID:112487"
                     /db_xref="HGNC:HGNC:20277"
     exon            1..224
                     /gene="DTD2"
                     /gene_synonym="ATD; C14orf126"
                     /inference="alignment:Splign:2.1.0"
     CDS             114..620
                     /gene="DTD2"
                     /gene_synonym="ATD; C14orf126"
                     /EC_number="3.1.1.96"
                     /note="probable D-tyrosyl-tRNA(Tyr) deacylase 2; putative
                     D-tyrosyl-tRNA deacylase 2; putative D-tyrosyl-tRNA(Tyr)
                     deacylase 2; L-alanyl-tRNA deacylase; animalia-specifc
                     tRNA deacylase; animalia-specific tRNA deacylase;
                     D-tyrosyl-tRNA deacylase 2 (putative)"
                     /codon_start=1
                     /product="D-aminoacyl-tRNA deacylase 2"
                     /protein_id="NP_542395.1"
                     /db_xref="CCDS:CCDS9643.1"
                     /db_xref="GeneID:112487"
                     /db_xref="HGNC:HGNC:20277"
                     /translation="MAEGSRIPQARALLQQCLHARLQIRPADGDVAAQWVEVQRGLVI
                     YVCFFKGADKELLPKMVNTLLNVKLSETENGKHVSILDLPGNILIIPQATLGGRLKGR
                     NMQYHSNSGKEEGFELYSQFVTLCEKEVAANSKCAEARVVVEHGTYGNRQVLKLDTNG
                     PFTHLIEF"
     exon            225..294
                     /gene="DTD2"
                     /gene_synonym="ATD; C14orf126"
                     /inference="alignment:Splign:2.1.0"
     exon            295..2713
                     /gene="DTD2"
                     /gene_synonym="ATD; C14orf126"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2689..2694
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DTD2"
                     /gene_synonym="ATD; C14orf126"
                     /note="hexamer: AATAAA"
     polyA_site      2713
                     /gene="DTD2"
                     /gene_synonym="ATD; C14orf126"
                     /note="major polyA site"
ORIGIN      
        1 aatcggcgca ggcccttcgt cgtgccccgc ctcgtctgcc ccgccagcgc gtcgagggag
       61 gggccagcga cacatggcct agtaactgtc cggccgcggc gctggcttaa gccatggctg
      121 agggtagccg gattcctcag gcccgggcgc tcctacagca gtgcctgcac gcccggctgc
      181 aaattcgccc agccgatggg gacgtcgcgg cccagtgggt ggaggtccaa agaggactgg
      241 tgatctacgt gtgctttttc aagggagctg ataaagaact tcttcccaaa atggttaata
      301 cactgttaaa tgtgaaatta agtgagacag aaaatggcaa gcatgtctct atattggatc
      361 tacctggcaa cattcttatt atccctcaag ctacccttgg aggaagacta aaaggaagaa
      421 acatgcaata tcactctaac tctggaaaag aagaagggtt tgaactttac tctcaatttg
      481 tgactctatg tgaaaaagaa gtagctgcta atagcaagtg tgctgaagct agggttgtag
      541 tggaacatgg cacttatggg aacaggcagg tgttaaagct ggacaccaac ggaccattca
      601 cacacttaat tgagttttga aaatgaaaaa ctagtttcta tagctgtttt ctggtatgaa
      661 atgatctaaa gtataattag attttcttcc ccttaatctt gaatatacta atcttcagca
      721 tttttagaca ggaaaatctt gggtttcata tataactctg cacctgctaa ttggatgact
      781 ttgccaagtc acctaaactc tggatctcag tcaccttttg tcctacattc ctctaccctt
      841 ctacttgaaa atttgaaata tgctgtctat tcacttcata gtcattaagg aaatgttctt
      901 aattgttttt ttgtttttgt tttttttttg agatggagtc ttgctctgtc gccagactgg
      961 agtgcagtgg cgcaatctcg gctcactgca acctccacct cctggattca agcgattctc
     1021 ctgcctcagc ctcccaagta gctgggatta caggcgcatg ccaccatgcc cagctaattt
     1081 ttttgtattt ttagtagaga tggggtttca ccgtgctggc caggatggtc tcgatctcct
     1141 gacctcgtga tccgcccacc tcggcctccc aaagtgctgg gactacaggc atgagccacc
     1201 gtgcccggcc tcttagttgt tttttaaaaa ttatgtacat tttaagtatt ttgcaatgaa
     1261 gaaattcatg caaacaagaa aaacacattt cttataccat caaatttgtg tagcatgtaa
     1321 taaaaataac tatttgtatt aaaattaggt aaacttcagc acaacccaat tataactttg
     1381 ttaattttgt ttactatttc agttttctgt atttccatat gtaagtcacc atttctttta
     1441 ataatatgca tgaaaatgta atatagggcc aaatgtggtg gctcatgcct ataatcccag
     1501 cactttggga ggccgaggtg ggaggatcac ttgagcccag gagtttgcga ccagcctggg
     1561 cagaatagca agacccagtc tctaacatat acatatacat atagatatat atgtaatata
     1621 gaagggttat tgtgtgttat attactttcc agggacattc aaatgtttta cattacttta
     1681 agaatcttta cttgatataa gaacaaagta taagggttta aaagttgttt ttattaaaca
     1741 tactatataa atgggttaat ggtctatttt tcagttttta ccaaaatcat gtgtctcact
     1801 ttttgtcttc gctttttaaa gaactggttc atgaaattag tgttagttca taaattgttt
     1861 aagaagttcc ttttccattg aattagattg ctgtaaaagg gagaaaaagg gaagcttccc
     1921 ataagaatag tttgaaaaca aattgacttg ttcatttcca tattatctgc ttgatgatat
     1981 ggagccagtg tcaatttttc tgttagtgaa tgttttggac tagatgttcc cgtccccaaa
     2041 atttatatgt tgaagccctt attaatgtga tggtatctgg agatggggct cctccaacca
     2101 tcccatcctg gaacatataa gccagaaaga aagtagtctc cagaaacaga ccatgctgac
     2161 accttgagtt tgaacttcta atcaccagaa ctgtgaggaa ataaatttct ggtgtttaaa
     2221 ccacccagtc ctatggtatt ttgttagggc agtctgagct acgacagtga tataagatag
     2281 acagctagta aggtaaactt ttcaaaggca agagaggaag atatacaaga aattgaaaga
     2341 ataattaagt cagtaagagg taatattcag ttttggcaaa ctcctctgac ttgagttgaa
     2401 aatacttttt ttttttaaga gtaaaaacca aataactaat tctaattggc aaaaaaaggt
     2461 aaataaataa acatcctaag tagctgctga aatttccgtt gtgtcttata gtttctttag
     2521 gtctgtgttc ctaagatgct taaaattttt atcatgaaaa atcctatttt ctctataccc
     2581 ttcctgtact gttctatttt ggaaccagag aatcaataac tggcttggta atgagctcat
     2641 tgtccttaac ttttgcttta ttgattcaca atacacttac tgaaatgtaa taaactattc
     2701 ataaacttgc aaa
//
