LOCUS       NM_001280542           11413 bp    mRNA    linear   PRI 06-AUG-2024
DEFINITION  Homo sapiens double PHD fingers 3 (DPF3), transcript variant 2,
            mRNA.
ACCESSION   NM_001280542
VERSION     NM_001280542.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 11413)
  AUTHORS   Liu,C., Chen,M., Xu,J., Yi,F., Li,X., Zhang,H., Wang,Y., He,S. and
            Jin,T.
  TITLE     DPF3 polymorphisms increased the risk of pulmonary tuberculosis in
            the Northwest Chinese Han population
  JOURNAL   Gene 927, 148617 (2024)
   PUBMED   38795855
  REMARK    GeneRIF: DPF3 polymorphisms increased the risk of pulmonary
            tuberculosis in the Northwest Chinese Han population.
REFERENCE   2  (bases 1 to 11413)
  AUTHORS   Verrillo,G., Obeid,A.M., Genco,A., Scrofani,J., Orange,F.,
            Hanache,S., Mignon,J., Leyder,T., Michaux,C., Kempeneers,C.,
            Bricmont,N., Herkenne,S., Vernos,I., Martin,M. and Mottet,D.
  TITLE     Non-canonical role for the BAF complex subunit DPF3 in mitosis and
            ciliogenesis
  JOURNAL   J Cell Sci 137 (9) (2024)
   PUBMED   38661008
  REMARK    GeneRIF: Non-canonical role for the BAF complex subunit DPF3 in
            mitosis and ciliogenesis.
REFERENCE   3  (bases 1 to 11413)
  AUTHORS   Cui,H., Yi,H., Bao,H., Tan,Y., Tian,C., Shi,X., Gan,D., Zhang,B.,
            Liang,W., Chen,R., Zhu,Q., Fang,L., Gao,X., Huang,H., Tian,R.,
            Sperling,S.R., Hu,Y. and Chen,W.
  TITLE     The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis
            of ccRCC by modulating TGF-beta signaling
  JOURNAL   Nat Commun 13 (1), 4680 (2022)
   PUBMED   35945219
  REMARK    GeneRIF: The SWI/SNF chromatin remodeling factor DPF3 regulates
            metastasis of ccRCC by modulating TGF-beta signaling.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 11413)
  AUTHORS   Protze,J., Naas,S., Kruger,R., Stohr,C., Kraus,A., Grampp,S.,
            Wiesener,M., Schiffer,M., Hartmann,A., Wullich,B. and Schodel,J.
  TITLE     The renal cancer risk allele at 14q24.2 activates a novel
            hypoxia-inducible transcription factor-binding enhancer of DPF3
            expression
  JOURNAL   J Biol Chem 298 (3), 101699 (2022)
   PUBMED   35148991
  REMARK    GeneRIF: The renal cancer risk allele at 14q24.2 activates a novel
            hypoxia-inducible transcription factor-binding enhancer of DPF3
            expression.
REFERENCE   5  (bases 1 to 11413)
  AUTHORS   Colli,L.M., Jessop,L., Myers,T.A., Camp,S.Y., Machiela,M.J.,
            Choi,J., Cunha,R., Onabajo,O., Mills,G.C., Schmid,V., Brodie,S.A.,
            Delattre,O., Mole,D.R., Purdue,M.P., Yu,K., Brown,K.M. and
            Chanock,S.J.
  TITLE     Altered regulation of DPF3, a member of the SWI/SNF complexes,
            underlies the 14q24 renal cancer susceptibility locus
  JOURNAL   Am J Hum Genet 108 (9), 1590-1610 (2021)
   PUBMED   34390653
  REMARK    GeneRIF: Altered regulation of DPF3, a member of the SWI/SNF
            complexes, underlies the 14q24 renal cancer susceptibility locus.
REFERENCE   6  (bases 1 to 11413)
  AUTHORS   Lange,M., Kaynak,B., Forster,U.B., Tonjes,M., Fischer,J.J.,
            Grimm,C., Schlesinger,J., Just,S., Dunkel,I., Krueger,T., Mebus,S.,
            Lehrach,H., Lurz,R., Gobom,J., Rottbauer,W., Abdelilah-Seyfried,S.
            and Sperling,S.
  TITLE     Regulation of muscle development by DPF3, a novel histone
            acetylation and methylation reader of the BAF chromatin remodeling
            complex
  JOURNAL   Genes Dev 22 (17), 2370-2384 (2008)
   PUBMED   18765789
  REMARK    GeneRIF: DPF3 adds a further layer of complexity to the BAF complex
            by representing a tissue-specific anchor between histone
            acetylations as well as methylations and chromatin remodeling.
REFERENCE   7  (bases 1 to 11413)
  AUTHORS   Zhang,H.S., Gavin,M., Dahiya,A., Postigo,A.A., Ma,D., Luo,R.X.,
            Harbour,J.W. and Dean,D.C.
  TITLE     Exit from G1 and S phase of the cell cycle is regulated by
            repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
  JOURNAL   Cell 101 (1), 79-89 (2000)
   PUBMED   10778858
REFERENCE   8  (bases 1 to 11413)
  AUTHORS   Phelan,M.L., Sif,S., Narlikar,G.J. and Kingston,R.E.
  TITLE     Reconstitution of a core chromatin remodeling complex from SWI/SNF
            subunits
  JOURNAL   Mol Cell 3 (2), 247-253 (1999)
   PUBMED   10078207
REFERENCE   9  (bases 1 to 11413)
  AUTHORS   Wang,W., Xue,Y., Zhou,S., Kuo,A., Cairns,B.R. and Crabtree,G.R.
  TITLE     Diversity and specialization of mammalian SWI/SNF complexes
  JOURNAL   Genes Dev 10 (17), 2117-2130 (1996)
   PUBMED   8804307
REFERENCE   10 (bases 1 to 11413)
  AUTHORS   Chestkov,A.V., Baka,I.D., Kost,M.V., Georgiev,G.P. and Buchman,V.L.
  TITLE     The d4 gene family in the human genome
  JOURNAL   Genomics 36 (1), 174-177 (1996)
   PUBMED   8812431
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC007160.3, AC006360.2,
            AL392024.3 and AC004828.2.
            
            On Oct 19, 2020 this sequence version replaced NM_001280542.2.
            
            Summary: This gene encodes a member of the D4 protein family. The
            encoded protein is a transcription regulator that binds acetylated
            histones and is a component of the BAF chromatin remodeling
            complex. Alternate splicing results in multiple transcript variants
            encoding different isoforms. [provided by RefSeq, Jul 2013].
            
            Transcript Variant: This variant (2) differs in the 3' CDS and the
            3' UTR compared to variant 1. The encoded isoform (2, also known as
            DPF3b) has a distinct C-terminus and is longer than isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038197.1921676.1,
                                           SRR14038193.109214.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000556509.6/ ENSP00000450518.1
            RefSeq Select criteria :: based on manual assertion, conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-45                AC007160.3         48475-48519
            46-206              AC006360.2         83283-83443
            207-314             AC006360.2         101805-101912
            315-442             AC006360.2         123242-123369
            443-538             AC006360.2         131448-131543
            539-617             AL392024.3         135538-135616       c
            618-755             AL392024.3         114191-114328       c
            756-884             AC004828.2         15610-15738
            885-997             AC004828.2         60242-60354
            998-1079            AC004828.2         69994-70075
            1080-11413          AC004828.2         70611-80944
FEATURES             Location/Qualifiers
     source          1..11413
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q24.2"
     gene            1..11413
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /note="double PHD fingers 3"
                     /db_xref="GeneID:8110"
                     /db_xref="HGNC:HGNC:17427"
                     /db_xref="MIM:601672"
     exon            1..45
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /inference="alignment:Splign:2.1.0"
     CDS             14..1150
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /note="isoform 2 is encoded by transcript variant 2; D4,
                     zinc and double PHD fingers, family 3; zinc finger protein
                     DPF3; BRG1-associated factor 45C; zinc finger protein
                     cer-d4"
                     /codon_start=1
                     /product="zinc finger protein DPF3 isoform 2"
                     /protein_id="NP_001267471.1"
                     /db_xref="CCDS:CCDS61497.1"
                     /db_xref="GeneID:8110"
                     /db_xref="HGNC:HGNC:17427"
                     /db_xref="MIM:601672"
                     /translation="MATVIHNPLKALGDQFYKEAIEHCRSYNSRLCAERSVRLPFLDS
                     QTGVAQNNCYIWMEKRHRGPGLAPGQLYTYPARCWRKKRRLHPPEDPKLRLLEIKPEV
                     ELPLKKDGFTSESTTLEALLRGEGVEKKVDAREEESIQEIQRVLENDENVEEGNEEED
                     LEEDIPKRKNRTRGRARGSAGGRRRHDAASQEDHDKPYVCDICGKRYKNRPGLSYHYA
                     HTHLASEEGDEAQDQETRSPPNHRNENHRPQKGPDGTVIPNNYCDFCLGGSNMNKKSG
                     RPEELVSCADCGRSGHPTCLQFTLNMTEAVKTYKWQCIECKSCILCGTSENDDQLLFC
                     DDCDRGYHMYCLNPPVAEPPEGSWSCHLCWELLKEKASAFGCQA"
     exon            46..206
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /inference="alignment:Splign:2.1.0"
     exon            207..314
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /inference="alignment:Splign:2.1.0"
     exon            315..442
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /inference="alignment:Splign:2.1.0"
     exon            443..538
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /inference="alignment:Splign:2.1.0"
     exon            539..617
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /inference="alignment:Splign:2.1.0"
     exon            618..755
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /inference="alignment:Splign:2.1.0"
     exon            756..884
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /inference="alignment:Splign:2.1.0"
     exon            885..997
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1079
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..11413
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      11394..11399
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /note="hexamer: AATAAA"
     polyA_site      11413
                     /gene="DPF3"
                     /gene_synonym="BAF45C; CERD4; SMARCG3"
                     /note="major polyA site"
ORIGIN      
        1 acattgtagc aaaatggcga ctgtcattca caaccccctg aaagcgctcg gggaccagtt
       61 ctacaaggaa gccattgagc actgccggag ttacaactca cggctgtgtg cagagcgcag
      121 cgtgcgtctt cccttcctgg actcacagac tggggtggcc cagaacaact gctacatctg
      181 gatggagaag aggcaccgag gcccaggcct tgccccgggc cagctgtata cataccctgc
      241 ccgctgctgg cgcaagaaga gacgattgca cccacctgaa gatccaaaac tgcggctgct
      301 ggagataaaa cctgaagtgg agcttcccct gaagaaggat gggttcacct cagagagcac
      361 cacgctggaa gccttgctcc gtggcgaggg ggttgagaag aaggtggatg ccagggagga
      421 ggaaagcatc caggaaatac agagggtttt ggaaaatgat gaaaatgtag aagaagggaa
      481 tgaagaagag gatttggaag aggatattcc caagcgaaag aacaggacta gaggacgggc
      541 tcgcggctct gcagggggca ggaggaggca cgacgccgcc tctcaggaag accacgacaa
      601 accttacgtc tgtgacatct gtggcaagcg ctacaagaac cgaccggggc tcagctacca
      661 ctatgctcac actcacctgg ccagcgagga gggggatgaa gctcaagacc aggagactcg
      721 gtccccaccc aaccacagaa atgagaacca caggccccag aaaggaccgg atggaacagt
      781 cattcccaat aactactgtg acttctgctt ggggggctcc aacatgaaca agaagagtgg
      841 gcggcctgaa gagctggtgt cctgcgcaga ctgtggacgc tctggtcacc caacctgcct
      901 gcagtttacc ctgaacatga ccgaggctgt caagacctac aagtggcagt gcatagagtg
      961 caaatcctgt atcctctgtg ggacctcaga gaatgatgac cagctactct tctgcgatga
     1021 ctgtgaccga ggctatcaca tgtactgttt aaatcccccg gtggctgagc ccccagaagg
     1081 aagctggagc tgccacttat gctgggaact gctcaaagag aaagcctcag cctttggctg
     1141 ccaggcctag ggccccaggt cacagaatgt gactcgctgc tggagatcct aaagcagagc
     1201 ccagttcaaa ccagaacgcg ccctcctccc acatatccag ccagaccaac tgcaaggaaa
     1261 agaaatagtc ccagaggggc agggacacat ggaacgaaga gggtgaggca tctcctgacc
     1321 tcccccgata tgtacggaac ttcagccagc acctccttgt ctctaccgga aggaagttgc
     1381 actttgggag aacacctccg gccccagccc tgtggaaccc ctctcacttt taccctagca
     1441 ccgaggccct ctcattggtt cccattttaa gggaagccat ttcctgacca ctcatccatt
     1501 acttgtgtgt agtgtggtgt ttttttatct attgtgttcc aagaaatctt ggcacagccc
     1561 ccgtgccccc agcttagggt ctgcatcctg aaattctcac ctgaggaaca aagggctgtg
     1621 gagaagttgt cgtttatggc aagcctcact ggaaacttct agacttgggg tcttgaaacc
     1681 ctttcttgtt ccttggtgtc tgtggagaca aagagttgcc ttctagaacc ccagcagtgg
     1741 catccacagc cagcctggtc ttgagccact gcttaaagtt actagatggg ggcggggagg
     1801 gagggagacg cgcagagaca tgggaggaaa cattgtggaa atggtgccaa ggccccgcca
     1861 tagccagtca gtacttgtta tccatcggga gagactttgc aagaggccag gctggttcct
     1921 tgaccttcag agctggggca tcctttaggt gagaccagtc atggcctatg gacagaggaa
     1981 gacggtcaag cctctgcctc tcagcccacc tggttctgga gacctggttc agcttctcct
     2041 ggtgggactg aagaaccagg aaggggagcg aaggctgccc aatcatgtgt ccgaatgctg
     2101 gatacagggg gctgcagctt tgagaaacct tcagtattga tgcgacgctc tgaattcctt
     2161 tttccaagta atttcttcct tccacgtagt gtttgttcgc tattgtctac tgagacctga
     2221 ctgggaattt taggatgggg gagagaagat tgttatctaa acaaataatt agggtgacat
     2281 ggtcattatt cacgaccagg gtggccacat tttagaactc tcagtgcggg ggctgctctt
     2341 gtctcctaag ctccccaaac atgcaggact cttgttttca aaaaaaaatg tgtctagaag
     2401 aaagaggtgg ggaggctgag cttccgagaa ctctgtgtgt tggaagatag ccccgagggc
     2461 tggagcggat tgggctgact ttgaatcgca gcagcagcac aataactgac atatttctgg
     2521 aaaaatcatt tgcccaaagg gcaggtctcg gtgagcggaa ccctcgcgca tgcttggctt
     2581 ctctgaaatc agctccatct ctgtggtctg gctgctcaca acaaaggccc aggttatttt
     2641 tagttcttca gctcctgagg acgctcccgg agactcgggc tagttgggcc acctctgccc
     2701 ggccgcagta tttgtgctgt ccctcggcag gagtgctcct ctctaggcta attgctcttg
     2761 gccagtggac ccagggcagc ctggcatgaa accaagcagt gtgggtctcc cccacgcttc
     2821 agcagagtga cctgtggcaa gcgatggggg tcactctcct gcaggggcct gtggcctcag
     2881 agggaatcac acacatacat aatggtctca tttaaagggc ccccgaccgg atggaatttt
     2941 catcttcctc ataagtaatt tccttccgcc tgctggtcgg tgagcttgtc tgaatcctga
     3001 aggcccaggg agggataggg agggtgacat tccatcagag gggcacattt tttctcctga
     3061 ctactccagc tctctctctt cccacaaaac ccaaagcagg ctgtctccaa aggctaataa
     3121 ttggttttga gcgtcatttt aatttaaatt tagaaaaaaa agttccccaa atgttcccaa
     3181 gtgccacaat agcttaaaag tttaaaaagc aagtccgaaa ccccaaactg tggctctaca
     3241 acttcacacg tcctcttcag agtatgtgca aatttgtttt ccacagaagt gcaggtgata
     3301 gggcagccct gttcgatctc agccccatgt ctgctctgcc tacacaagct gagcctcagc
     3361 tgggtctccc aggccaaggc agggcactgg aacttgcctg cactggtgag ggtcagggct
     3421 ctggagtgac gttaggatgg ccccggagtt cccctctcag cttcattact ccctgaagaa
     3481 tgggcccaac ccattcttca tctttggagg cctcagtttc cccatctgga aagcggggat
     3541 agcaagccag cttgtgggct ggcactgtca gggtactaca agcagacaaa agtctccgtg
     3601 gtcacattta tcacctctgt gttcaaaaga ggacggggtt ggtaaacttt aaattggtct
     3661 cttttttttg aaccccagag aatgagatag aatcatagga tgcatgtgaa ggatcagagt
     3721 ttttgtgttg cctctgccat ggagtagctg tgtgacactg ggcaagtcac ctaacctccc
     3781 tgaacctcaa ttgcccacct ggaaagtgga gatagtaaca cttgccctgc ctattccaga
     3841 gtgacactgg gactcttaag catcatgtta cataaacaag cactgcagag ccatgcttgt
     3901 ctgggaagaa ctccggatgt tttccatgtc cgccttcttg tgtgcattag ccaatgttag
     3961 acgtcttctt caaatctccc ttgtgaccaa agggagttta tattgccagg gctgggctgc
     4021 gaccaaggaa atcatgactt gcatgggctg tggggtggag gtgagggatg tacatggggt
     4081 tggggacttt aaaatgaagg tactcaggat actccttcta taagattaat gcagttgaga
     4141 atggaaaggt gacttttaga gagggctatg atttgtttca gttcatgggt aacgctcact
     4201 ttccgaccaa cactgccact ttctagctga ctgaccttgg gccaatgact tcaactctct
     4261 gagcctcatt tcacatgtct gtaaggtggg gaaacatggc ctatccagca tggtctttgc
     4321 aggtattcaa ggtgacattg gtaaagatcc tggcccgggt ctggcatgat gatggtcccc
     4381 actccatggt agctattgtc attttctgca gaggccacca aatggagata atgatgtggt
     4441 tgtcttccgg ctcaaatgct gggaacagcc aggagaactt tgctgggctt cacccctctg
     4501 tactgtggct ccagcaaacc agagaggtga ggctgccaga cccaaccgga agtggaaatc
     4561 ctgtttcctg taggcatttt tgaaaccctg ctttttggat ctgtagcaaa tccagtgcag
     4621 gcaacattat gtggaaatag aaacagggct cctgctagga gattgacatt ctggctttcc
     4681 tttggaaccc ctcactgact catcgcccct gaagcaggag ccagcaggtc ccaaggctcc
     4741 cctgctcctg tccctgcccc agggcgaggt aggaagccgg aagcctgggc aggctgagcc
     4801 cagccgactg gaaccaggga agagcctgtg ggtgggtgga agggagggaa ggaggccaga
     4861 ttcctccaga actggggaag agaacaggtt ttgaagttgg gggagggttt gggtttcaca
     4921 gtgatggttt catgataccc tggagggttg cacactcctg gtgcattttt gtattcgtgc
     4981 tttgaataca gcccgcttcc tttcaaccct ccgcttaaaa agttttgatg ttttaaggaa
     5041 gaaaaatgag atgattgtta ttacttttcc tttcggggca agtggaggag acctgtgctc
     5101 ttttatgccg ctgaagaaag gttgctggca acctcaggcc tcaggactca aagaagaggg
     5161 gcttatagtc tcctctttgg gtctgtgtgt gaggaggtag ggggtgttgc gccgcccgtg
     5221 gcccagggcg ggccctgagg accacatccc tgccccccag gctggttttt agcctgtcgt
     5281 ggaagtgctg ggacagaagc agccccttct tctctcactc cccggctgcc cctcctagcc
     5341 cctcttcagg gggtccccat gtctcagccc gagggagaag ttggctctgg ccagagccac
     5401 gctcacactc ccacaggatg ccgcaagtcc caggcctggc tcctggtagc agtggtgact
     5461 tggtgtccct tttagcaggc ttccattcct ggggagggag aaagacaggg gtgcctgggg
     5521 aagggagggt gggagggcat ttgggagggg tgaggatctc tggtggaaaa aggcagagag
     5581 ctggatgtcc tcagggagaa atcctcgagc taaggagctg gagggcagca ggtgggagtg
     5641 aacagtgatt gtaactcttt tttttttttc tgaggcttgt gatcctgggc aacagattat
     5701 tattattatt attttgtaaa aaggccaaac ctctgcccag ttctgaacac tgattcagct
     5761 ccctctttct tgaggccgcc cgttggttgt gtggggtttc agggatgctt ctgagggcaa
     5821 agtaagcccc tcacccagct ggggagagaa ggcagtgagg gagggctgga tcatgcctgc
     5881 agccttgggg agtgaagcat ttccaggcac tgctaccaga ggggtcaggc ccccaggccc
     5941 ctgtccccca agcccaggac accagtagct gggaagggaa gagggggact ggccatcctg
     6001 ctcctctccc ctctgcaaag tggacagagc tcctcctctt cctgctgtgt gttgcccgtt
     6061 ttgaaatctt actcccatcc ccaaagtatg cttttggata ccaggtgaag gggaaggatg
     6121 gtgatggtgg ggaacagctg ttttaatttg cctcaggcct atgaatctcc ctacctgaac
     6181 cccagcttgc catagagtct aactggtccg tggtcagaag gtgggctcca tagctgtctg
     6241 ggggttgggg ctccctcccc catttctgag cattcccagg gtttgggagt ctgcttatga
     6301 ttctctgcca gaggccacgg ccaccagccc tgagtgtgga aacaatggga cagatgggtt
     6361 ggttcaaggc ctttgggcag ctggtggtgg gtcttggaga gctgggaacc ccttcctagg
     6421 gaggctggag accctctggt ctgtgagtgg acagctgaga gtggggcagg gggaaggagg
     6481 ggagaggaag atgggggtgc ttcctgctgg gcacccggga tgtgggagga tagacaacct
     6541 cccaggcaga gcgagtggga actgccttag agcctctcag cagctgtccc cggggaggcc
     6601 tggctgtgcg gcgggcgccc cctccatgtg cgcagcccag gcagctagaa gagaggccca
     6661 aaggaagagc tgtcaggaaa ctctgaggag gaggggtccg ggcttgccag ttccgtacca
     6721 tgggttttct agaaggaaca gggaactccc tgcatgaggg gaaagatttg gaagtgagtg
     6781 ggttcctggg aacaggctct ctctgggttc tgagtgagcc ctggctgtga gggggtcctg
     6841 aggtgactcc ccagggccct ttgttccagc ttctgtcccc actccttccc tttctctgct
     6901 ccagtgccaa cctcaggtca tagggcaggt ggccttgaga gagggacctt ccacagttcc
     6961 ccttctttgg ctccaccagg agaagggagt attttgctga tggcgacatt tcccagggca
     7021 ggccagagga aggcaggaac caggactggc aggcagccag aaccctcttg gacagagata
     7081 taattactta tcatgacctc tagcccaggc attgagcaaa atggccctgt aggctggcac
     7141 caaccctgtc tagcaaataa acgcggccat ggtggggacg ggagggcagg taagtgggcc
     7201 ttgtaggaaa tggcagaggc ctgtgagccc ctggggccta tatattccct cagcaacaca
     7261 accctacaga ctcccaggtt atattttcac tcactgcatc ccatttgctc atttgctcgc
     7321 ctctctgcat ctctgttctt catttcaatg ttatgaatat tgatgatgag aacaggaatg
     7381 cccatgtgca tgcgcgtgcg tgcacgcacg cacatacaca cacacacaca cacacacaca
     7441 cacacacaca cacgccctac ttaatgaacc aaagggaaac tttgatgttg ctccaggaca
     7501 agagggagag ccaggggctg ccaggcaagg tgcatctttc ctgaagtctt ctccagtcct
     7561 gctcctccag ctctcagcct ctgcacagcc accagggttg caaagggagc cttgtgcttg
     7621 gaaagctact ggctccgcga cctctctcct tctcttccct tcgttcacct atgcttcttt
     7681 tcatgaaaga tatttggcaa tagttgggta cttcaaaagt ctcaattctg ctatcaaagg
     7741 gatgcaaagc ttttatggct agaatggggt ttgtggttta tacggacttg gtttgccctt
     7801 ccatgtctac tccccactga gaccctgatt ctcctcctgc cctctccctt ccctgcactg
     7861 tttcctccct tccctctgcc gtgatagatg ctaaggagtg gggtggaggt gggaagtggg
     7921 aagcaacagt ggcgtatagg aaaaagaaaa tataccccgt gcacattttc aacatgtagt
     7981 tgaagaagcc taaattaggt actagaaaaa aaaaaaggac agaaacactg cctgatatgt
     8041 gagcaagagc atgaaaatat agaatgatta tctcagagca gaggaggtgg ggagcaggtg
     8101 gctggagaga ggcggggtag gtaggcaggg cgtccctggc tcaccaatgc gtctggtcca
     8161 catggcattt gggaaagcag atgggtcatg cttttgcaat gaatggtcag atgcttaggg
     8221 ggcatttgtg ctcctctggc caggaaaggg aacagagtcc atccaagctg ccccccactc
     8281 atctgccatg gttgtccacc ctgggggttt ttcctctgaa ggaaaatgaa cccatctttt
     8341 gcctgccatg aatcattgca gggcaggctg ttactggcta aattaaaacc cttggcaggg
     8401 catcgactgt gtgcgaggca atgctctagg tcctgtaggg gctggaaaat aaaccgcatg
     8461 ctggcctagc cttcaagttg cttttcagcc atgaaattaa gctctgccaa gcaatcgtga
     8521 ttgtaggtca agtatcgcgc catcacggaa ggtgtaagta tatgtaggtt tctctgttga
     8581 ggatgcgtgt tcctcagtag aagacaagca ggtggaggca tccagtgatt tctaccctgt
     8641 ggaggctgag gggtcggggg aagaaaacag atgacctcag cctagttgct ttaatctgct
     8701 tttccaagca ctggatgccc ttggatgaca gcatcctcag cattaaaact ggtgaactga
     8761 tgaagtcacc tggcctggag tgtgttgggc agccagtgtc cccagagctg cttgtgggtt
     8821 tctggggtgg aaggcaggga ggtgcaactg gcagggcctg atcagaggca gaaaatgacc
     8881 cccacagtgg tcttttccct gctagagaaa gcagagagcg ggactggggg ggtgggggct
     8941 tcaagtacag attgggcaca ctccaccaga ccccagcaag gtcagctgcc ccacgcctgt
     9001 atctggcact gctggtgtgt gcagggatga aacccagcat cagagaggtt ttcagcaaac
     9061 cttccatgct cacctttggc caggtgcttg tcagatccta gcttcgtgct ggcttagact
     9121 ctcagttgtt tgtgttgaca gcattaggaa taaaccgttt gtttcatctt tccttttctc
     9181 cacacgtgtc acagccagat ttcagctttg agttattccc tgaagaagcc acaccaacct
     9241 tgctttcaag caaaatgcct gggcttgggg gaaggtgtgt atctgtccat gtgtggatgt
     9301 tggctcagag ctatagcttc tctgtggggg gtggcccaag ggaaggctcc tctggggccc
     9361 tggatggcac atgactccca gtgaggagaa ttctggtgat ctctgtggag gtagtcaggg
     9421 acacaaggct tggctgtgag tctggtttta aagtgcgtga cagcctgaaa agcatgcagg
     9481 ggtttggtcc actcacctac ttgaaagcct gtgggcaacg ttcttttgag ccaagacttc
     9541 tctgaatggc cctgctggtg gaaggggtga ggcaaaggcc tctgacttgg accctttcca
     9601 caccagactg gcagcacttc ccccaggcag ccagtggtgg gccctgagcc ctcaggtccc
     9661 cagctccttg agggatgaac ctgggagccc aagagccagt ggctgagctc tgagaaggct
     9721 ccatctccca cctgcccttg agcgcgctct caggctgaga acacggtctc atcaggcgcc
     9781 ttcctggcct gatgctgtgc tgtctacgtc acacggtcga ttcacaaaag ccagaactag
     9841 acctcaacca ggtcatctcc ccgttgccaa gtgggttcag ggtgagggca atttgtaagc
     9901 tcaatttctc tgacagccaa gacatggagc atctctgcta agaagccaaa agaaattggt
     9961 tttcttcttc tcattgctga agcccctctg tgtctcttct cagggacagg ctggtccagt
    10021 ggctttggtg agggcgcctc catttgtgaa cgctgggatt cctctgggtg ggctttggca
    10081 ggtggctcct atggtaggaa ggatgaccag gtccctggga atgagctgcc tacctgctgc
    10141 tccacgagga agctcaggcc tgcacaggct ccaccaggcc ttggatgccc tctagttgag
    10201 tcagagaccc tggaaacaca ctgagatctc caattgctgc ctccattgat gtctctagac
    10261 ctgcagatac gaagcaaacc tgggattgct tcttccaggt atgggcacca gagagggaag
    10321 ccactgcaac attttatccc catcattcca aaatgcttgc ttgtctcttt tacctcacac
    10381 tcacaactcc ttctgagact ctcagtcata aaggaatgac caagagagtg ggtctccagt
    10441 gagagaaatg cctatgaaag agggtttccc tttttgctct tttgaacacc ctccccactg
    10501 atccttggga cccaacgccg cattgcctct tgcagatgag gttttgcctt gggctgcttt
    10561 ggtacttcag accaggactg agtctgacac agctttcatg aggttacaga aaagggctac
    10621 agatttggga agctgtgtgt aatggtcttg agacaatatc tccatttggc ccaccctggc
    10681 ttctctaaaa agcaacgaca gcaacagaca aacaaaaagc tcccacctcc caccccgtta
    10741 gctgtcctcc tccttcactg tgatgtggtt gcggtctctg taggtgtgtg tgccaccctt
    10801 gtcctctgtc ctctggggat gtgcccttcc cacgtgtgtc aggttcccac tctttcgtgg
    10861 ttcctaacgt gaagtgctgt gatgtttctg ccctgcctaa ggaacgtatc aagctctctc
    10921 agtgtttcag tgttggagat tgaggctgtg ccacatcttc tgccatccta aggggacatg
    10981 atggttctgt gattcccaga gagctggcag attgtgacaa tctccaggag aacctacaga
    11041 ttggaagcag cccacacctg atgtggactc ctgacccggg actcactctt cattcagaag
    11101 actggtggcc cacgtgccag gaccacccca cctctcttgc tgccttttct cctgtcctga
    11161 tggggttctg ggagggagac ctgtcgctga tgagatgaag aatgtgggga tcgagcagcc
    11221 ttcttctttg ggacccctcg atatcccatg gaatgctcgc acgttctcaa agactgagtc
    11281 acaagcccct accccttcct tgctgtggtt agtatcttgt tctgtgattg gttagcaatg
    11341 ttgactaccc acgtagtgaa tcttttgtct gcaatttaga gaatgtgtaa acaaataaaa
    11401 ggctttaaaa ctc
//
