LOCUS       NM_001135155            2301 bp    mRNA    linear   PRI 21-SEP-2024
DEFINITION  Homo sapiens double PHD fingers 1 (DPF1), transcript variant 1,
            mRNA.
ACCESSION   NM_001135155
VERSION     NM_001135155.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2301)
  AUTHORS   Persson,B.D., Nord,S., Lindqvist,R., Danskog,K., Overby,A.K.,
            Kohl,A., Willison,H.J., Lenman,A. and Arnberg,N.
  TITLE     BAF45b Is Required for Efficient Zika Virus Infection of HAP1 Cells
  JOURNAL   Viruses 13 (10), 2007 (2021)
   PUBMED   34696437
  REMARK    GeneRIF: BAF45b Is Required for Efficient Zika Virus Infection of
            HAP1 Cells.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2301)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 2301)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 2301)
  AUTHORS   Yin,Y., Morgunova,E., Jolma,A., Kaasinen,E., Sahu,B.,
            Khund-Sayeed,S., Das,P.K., Kivioja,T., Dave,K., Zhong,F.,
            Nitta,K.R., Taipale,M., Popov,A., Ginno,P.A., Domcke,S., Yan,J.,
            Schubeler,D., Vinson,C. and Taipale,J.
  TITLE     Impact of cytosine methylation on DNA binding specificities of
            human transcription factors
  JOURNAL   Science 356 (6337) (2017)
   PUBMED   28473536
REFERENCE   5  (bases 1 to 2301)
  AUTHORS   Dykhuizen,E.C., Hargreaves,D.C., Miller,E.L., Cui,K., Korshunov,A.,
            Kool,M., Pfister,S., Cho,Y.J., Zhao,K. and Crabtree,G.R.
  TITLE     BAF complexes facilitate decatenation of DNA by topoisomerase
            IIalpha
  JOURNAL   Nature 497 (7451), 624-627 (2013)
   PUBMED   23698369
REFERENCE   6  (bases 1 to 2301)
  AUTHORS   Battaglioli,E., Andres,M.E., Rose,D.W., Chenoweth,J.G.,
            Rosenfeld,M.G., Anderson,M.E. and Mandel,G.
  TITLE     REST repression of neuronal genes requires components of the
            hSWI.SNF complex
  JOURNAL   J Biol Chem 277 (43), 41038-41045 (2002)
   PUBMED   12192000
REFERENCE   7  (bases 1 to 2301)
  AUTHORS   Klochendler-Yeivin,A., Muchardt,C. and Yaniv,M.
  TITLE     SWI/SNF chromatin remodeling and cancer
  JOURNAL   Curr Opin Genet Dev 12 (1), 73-79 (2002)
   PUBMED   11790558
  REMARK    Review article
REFERENCE   8  (bases 1 to 2301)
  AUTHORS   Zhang,H.S., Gavin,M., Dahiya,A., Postigo,A.A., Ma,D., Luo,R.X.,
            Harbour,J.W. and Dean,D.C.
  TITLE     Exit from G1 and S phase of the cell cycle is regulated by
            repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
  JOURNAL   Cell 101 (1), 79-89 (2000)
   PUBMED   10778858
REFERENCE   9  (bases 1 to 2301)
  AUTHORS   Phelan,M.L., Sif,S., Narlikar,G.J. and Kingston,R.E.
  TITLE     Reconstitution of a core chromatin remodeling complex from SWI/SNF
            subunits
  JOURNAL   Mol Cell 3 (2), 247-253 (1999)
   PUBMED   10078207
REFERENCE   10 (bases 1 to 2301)
  AUTHORS   Chestkov,A.V., Baka,I.D., Kost,M.V., Georgiev,G.P. and Buchman,V.L.
  TITLE     The d4 gene family in the human genome
  JOURNAL   Genomics 36 (1), 174-177 (1996)
   PUBMED   8812431
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC011479.7 and BC125153.1.
            
            On Jun 1, 2020 this sequence version replaced NM_001135155.2.
            
            Transcript Variant: This variant (1) uses an alternate in-frame
            splice site in the 3' coding region, compared to variant 4. The
            encoded protein (isoform a) is shorter, compared to isoform d.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038196.3261988.1, BC125153.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2157437 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000355526.10/ ENSP00000347716.5
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                AC011479.7         95156-95244
            90-1333             BC125153.1         20-1263
            1334-2301           AC011479.7         107405-108372
FEATURES             Location/Qualifiers
     source          1..2301
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.2"
     gene            1..2301
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /note="double PHD fingers 1"
                     /db_xref="GeneID:8193"
                     /db_xref="HGNC:HGNC:20225"
                     /db_xref="MIM:601670"
     exon            1..109
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..1244
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /note="isoform a is encoded by transcript variant 1;
                     neuro-d4 homolog; zinc finger protein neuro-d4;
                     BRG1-associated factor 45B; D4, zinc and double PHD
                     fingers family 1"
                     /codon_start=1
                     /product="zinc finger protein neuro-d4 isoform a"
                     /protein_id="NP_001128627.2"
                     /db_xref="CCDS:CCDS46064.2"
                     /db_xref="GeneID:8193"
                     /db_xref="HGNC:HGNC:20225"
                     /db_xref="MIM:601670"
                     /translation="MATVIPGPLSLGEDFYREAIEHCRSYNARLCAERSLRLPFLDSQ
                     TGVAQNNCYIWMEKTHRGPGLAPGQIYTYPARCWRKKRRLNILEDPRLRPCEYKIDCE
                     APLKKEGGLPEGPVLEALLCAETGEKKIELKEEETIMDCQKQQLLEFPHDLEVEDLED
                     DIPRRKNRAKGKAYGIGGLRKRQDTASLEDRDKPYVCDICGKRYKNRPGLSYHYTHTH
                     LAEEEGEENAERHALPFHRKNNHKQFYKELAWVPEAQRKHTAKKAPDGTVIPNGYCDF
                     CLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTS
                     ENDDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCLRHLKEKASAYITLT"
     exon            110..270
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            271..378
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            379..506
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            507..596
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            597..675
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            676..807
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            808..858
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            859..978
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1091
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1173
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /inference="alignment:Splign:2.1.0"
     exon            1174..2301
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2271..2276
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /note="hexamer: ATTAAA"
     polyA_site      2301
                     /gene="DPF1"
                     /gene_synonym="BAF45b; NEUD4; neuro-d4; SMARCG1"
                     /note="major polyA site"
ORIGIN      
        1 tgggcggcct cagcgcccgc ccgaccgctg ggaggaccga cccggcgggg acctgctggg
       61 ggcaggaccc ggggagcaag atggccactg tcatccctgg ccccctgagc ctaggcgagg
      121 acttctaccg cgaggccatc gagcactgcc gcagttacaa cgcgcgcctg tgcgccgagc
      181 gcagcctgcg actgcccttc ctcgactcgc agaccggcgt ggcccagaac aactgctaca
      241 tctggatgga gaagacccac cgcgggccgg gtttggcccc gggacagatt tacacgtacc
      301 ccgcccgctg ttggaggaag aaacggagac tcaacatcct ggaggacccc agactcaggc
      361 cctgcgagta caagatcgac tgtgaagcac ccctgaagaa ggagggtggc ctcccggaag
      421 ggccggtcct cgaggctcta ctgtgtgcag agacggggga gaagaagatt gagctgaagg
      481 aggaggagac cattatggac tgtcagaaac agcagttgct ggagtttccg catgacctcg
      541 aggtggaaga cttggaggat gacattccca ggaggaagaa cagggccaaa ggaaaggcat
      601 atggcatcgg gggtctccgg aaacgccagg acaccgcttc cctggaggac cgagacaagc
      661 cgtatgtctg tgatatctgt gggaaacggt ataagaaccg gccggggctc agctaccact
      721 acacccacac ccacctggcc gaggaggagg gggaggagaa cgccgaacgc cacgccctgc
      781 ccttccaccg gaaaaacaac cataaacagt tttacaaaga attggcctgg gtccctgagg
      841 cacaaaggaa acacacagcc aagaaggcgc ccgacggcac tgtcatcccc aacggctact
      901 gtgacttctg cctggggggc tccaagaaga cggggtgtcc cgaggacctc atctcctgtg
      961 cggactgtgg gcgatcagga cacccctcgt gtttacaatt cacggtgaac atgacggcag
     1021 ccgtgcggac ctaccgctgg cagtgcatcg agtgcaaatc ctgcagcctg tgcggaacct
     1081 ccgagaacga cgaccagctg ctgttttgtg atgactgcga tcggggttac cacatgtact
     1141 gcctgagtcc ccccatggcg gagcccccgg aagggagctg gagctgtcac ctctgtctcc
     1201 ggcacctgaa ggaaaaggct tctgcttaca tcaccctcac ctaggccggc tcggctcgcc
     1261 gcgactctgg ggtggtgctc gcctacctgc ctctccgagc tcctcaattc tcccccaccc
     1321 tgaacatccc gcagggggag ggggagaggg ggaagccgag agggggctgg gccaccccct
     1381 cccctctgtg caagtggaat gtctgccctg tgggtgggtg ggcccggcca gggcctctcc
     1441 ctccctccct ccctctctgt cccttggcaa atggacacca ggggcttctc ccctcaaagc
     1501 cataccccgc ctctgggcgg gcatgggggg tggtgggtgc cagccagggg catggacaga
     1561 gcctttttct aaagaaaaag acaaaaagtt aaaaaaaaaa aaaagaagaa aagaaaagaa
     1621 gttaatatat acaaagagtc ctccaaggcc tggctgggtg gaggggcgct gctgagagtg
     1681 tccaccgggc acccgcctct gccggccccc cgccgggcgc cccaacccca atttctggag
     1741 ctgcagccgt cccgcgcccc acccaaggtg ggcgccttcc cctcttgtgc ccagggcggt
     1801 gggcgtggtg tccacccgcc cctcctggtg cccacggtgg atactgcatg atgtgaacct
     1861 tggttttgaa ctctgttcct gcccctcccc gaccgcccca gcctgtgccc gccccgtgcc
     1921 tgccgtggct ggtgggtggc ggtggtgggg ccgggtgggc ccccgcccag cgcctgctgg
     1981 aatgagaagc acagactccg ccacggactc cttttctctc cctcctcccg ccccgccagg
     2041 cctggcggcc cccgcccccc tcgctggcca ttttggggga gtgagggggc gtggttgttt
     2101 cttgtggttg tgtgtgtttg ttgttcgggt tttaaaaaag ggaaactgag actgcaggtg
     2161 ggggaggtgg tgggttttgg ggggatgtcc cctaatccag gagtgccccc tcacttgtca
     2221 ccgagtctcc tctattgcct gcctctgctg tgaattaact tgttctgtgt attaaactgg
     2281 gcctgacccc tctgcccacg a
//
