LOCUS       NM_001366683            7631 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens dedicator of cytokinesis 9 (DOCK9), transcript variant
            13, mRNA.
ACCESSION   NM_001366683 XM_017020516
VERSION     NM_001366683.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7631)
  AUTHORS   Eijsbouts,C., Zheng,T., Kennedy,N.A., Bonfiglio,F., Anderson,C.A.,
            Moutsianas,L., Holliday,J., Shi,J., Shringarpure,S., Voda,A.I.,
            Farrugia,G., Franke,A., Hubenthal,M., Abecasis,G., Zawistowski,M.,
            Skogholt,A.H., Ness-Jensen,E., Hveem,K., Esko,T., Teder-Laving,M.,
            Zhernakova,A., Camilleri,M., Boeckxstaens,G., Whorwell,P.J.,
            Spiller,R., McVean,G., D'Amato,M., Jostins,L. and Parkes,M.
  CONSRTM   23andMe Research Team; Bellygenes Initiative
  TITLE     Genome-wide analysis of 53,400 people with irritable bowel syndrome
            highlights shared genetic pathways with mood and anxiety disorders
  JOURNAL   Nat Genet 53 (11), 1543-1552 (2021)
   PUBMED   34741163
  REMARK    GeneRIF: Genome-wide analysis of 53,400 people with irritable bowel
            syndrome highlights shared genetic pathways with mood and anxiety
            disorders.
REFERENCE   2  (bases 1 to 7631)
  AUTHORS   Karolak,J.A., Rydzanicz,M., Ginter-Matuszewska,B., Pitarque,J.A.,
            Molinari,A., Bejjani,B.A. and Gajecka,M.
  TITLE     Variant c.2262A>C in DOCK9 Leads to Exon Skipping in Keratoconus
            Family
  JOURNAL   Invest Ophthalmol Vis Sci 56 (13), 7687-7690 (2015)
   PUBMED   26641546
  REMARK    GeneRIF: c.2262A>C substitution in DOCK9 leads to a splicing
            aberration. However, because the mutation effect was observed in
            vitro, a definitive relationship between DOCK9 and KTCN phenotype
            could not be established.
REFERENCE   3  (bases 1 to 7631)
  AUTHORS   Blandin,G., Marchand,S., Charton,K., Daniele,N., Gicquel,E.,
            Boucheteil,J.B., Bentaib,A., Barrault,L., Stockholm,D., Bartoli,M.
            and Richard,I.
  TITLE     A human skeletal muscle interactome centered on proteins involved
            in muscular dystrophies: LGMD interactome
  JOURNAL   Skelet Muscle 3 (1), 3 (2013)
   PUBMED   23414517
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7631)
  AUTHORS   Rittinger,K.
  TITLE     Snapshots form a big picture of guanine nucleotide exchange
  JOURNAL   Sci Signal 2 (91), pe63 (2009)
   PUBMED   19809089
  REMARK    GeneRIF: Studies indicate that that many of the mechanistic
            principles of the exchange process are conserved in the
            DOCK9-catalyzed reaction.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7631)
  AUTHORS   Yang,J., Zhang,Z., Roe,S.M., Marshall,C.J. and Barford,D.
  TITLE     Activation of Rho GTPases by DOCK exchange factors is mediated by a
            nucleotide sensor
  JOURNAL   Science 325 (5946), 1398-1402 (2009)
   PUBMED   19745154
  REMARK    GeneRIF: through structural analysis of DOCK9-Cdc42 complexes, we
            identify a nucleotide sensor within the alpha10 helix of the DHR2
            domain that contributes to release of guanine diphosphate (GDP) and
            then to discharge of the activated GTP-bound Cdc42
REFERENCE   6  (bases 1 to 7631)
  AUTHORS   Meller,N., Westbrook,M.J., Shannon,J.D., Guda,C. and Schwartz,M.A.
  TITLE     Function of the N-terminus of zizimin1: autoinhibition and membrane
            targeting
  JOURNAL   Biochem J 409 (2), 525-533 (2008)
   PUBMED   17935486
  REMARK    GeneRIF: novel functions for the N-terminal region of zizimin1.
REFERENCE   7  (bases 1 to 7631)
  AUTHORS   Detera-Wadleigh,S.D., Liu,C.Y., Maheshwari,M., Cardona,I.,
            Corona,W., Akula,N., Steele,C.J., Badner,J.A., Kundu,M., Kassem,L.,
            Potash,J.B., Gibbs,R., Gershon,E.S. and McMahon,F.J.
  CONSRTM   NIMH Genetics Initiative for Bipolar Disorder Consortium
  TITLE     Sequence variation in DOCK9 and heterogeneity in bipolar disorder
  JOURNAL   Psychiatr Genet 17 (5), 274-286 (2007)
   PUBMED   17728666
  REMARK    GeneRIF: DOCK9 contributes to both risk and increased illness
            severity in bipolar disorder.
            GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   8  (bases 1 to 7631)
  AUTHORS   Cote,J.F. and Vuori,K.
  TITLE     Identification of an evolutionarily conserved superfamily of
            DOCK180-related proteins with guanine nucleotide exchange activity
  JOURNAL   J Cell Sci 115 (Pt 24), 4901-4913 (2002)
   PUBMED   12432077
REFERENCE   9  (bases 1 to 7631)
  AUTHORS   Meller,N., Irani-Tehrani,M., Kiosses,W.B., Del Pozo,M.A. and
            Schwartz,M.A.
  TITLE     Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho
            proteins
  JOURNAL   Nat Cell Biol 4 (9), 639-647 (2002)
   PUBMED   12172552
  REMARK    GeneRIF: Sequence comparison combined with mutational analysis
            identified a new domain, which we named CZH2, that mediates direct
            interaction with Cdc42
REFERENCE   10 (bases 1 to 7631)
  AUTHORS   Christian,S.L., McDonough,J., Liu Cy,C.Y., Shaikh,S., Vlamakis,V.,
            Badner,J.A., Chakravarti,A. and Gershon,E.S.
  TITLE     An evaluation of the assembly of an approximately 15-Mb region on
            human chromosome 13q32-q33 linked to bipolar disorder and
            schizophrenia
  JOURNAL   Genomics 79 (5), 635-656 (2002)
   PUBMED   11991713
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL139084.9 and AL161420.10.
            
            On Jun 2, 2019 this sequence version replaced NM_001366683.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR18074969.819836.1,
                                           SRR14038191.2812172.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000682017.1/ ENSP00000507034.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-281               AL139084.9         37561-37841         c
            282-398             AL139084.9         15212-15328         c
            399-488             AL161420.10        153161-153250       c
            489-571             AL161420.10        148830-148912       c
            572-641             AL161420.10        146295-146364       c
            642-737             AL161420.10        145044-145139       c
            738-872             AL161420.10        143947-144081       c
            873-1047            AL161420.10        138322-138496       c
            1048-1115           AL161420.10        137321-137388       c
            1116-1190           AL161420.10        127625-127699       c
            1191-1331           AL161420.10        125965-126105       c
            1332-1535           AL161420.10        125281-125484       c
            1536-1658           AL161420.10        124771-124893       c
            1659-1741           AL161420.10        121172-121254       c
            1742-1864           AL161420.10        120481-120603       c
            1865-1944           AL161420.10        111625-111704       c
            1945-2132           AL161420.10        111353-111540       c
            2133-2198           AL161420.10        111151-111216       c
            2199-2291           AL161420.10        109525-109617       c
            2292-2415           AL161420.10        108701-108824       c
            2416-2537           AL161420.10        107964-108085       c
            2538-2624           AL161420.10        106806-106892       c
            2625-2714           AL161420.10        106035-106124       c
            2715-2830           AL161420.10        104885-105000       c
            2831-2900           AL161420.10        104551-104620       c
            2901-3026           AL161420.10        103540-103665       c
            3027-3098           AL161420.10        102891-102962       c
            3099-3245           AL161420.10        91224-91370         c
            3246-3329           AL161420.10        90921-91004         c
            3330-3441           AL161420.10        90418-90529         c
            3442-3620           AL161420.10        86363-86541         c
            3621-3734           AL161420.10        86012-86125         c
            3735-3852           AL161420.10        83398-83515         c
            3853-3986           AL161420.10        78891-79024         c
            3987-4101           AL161420.10        76401-76515         c
            4102-4168           AL161420.10        73040-73106         c
            4169-4216           AL161420.10        71585-71632         c
            4217-4353           AL161420.10        68917-69053         c
            4354-4469           AL161420.10        60487-60602         c
            4470-4607           AL161420.10        54642-54779         c
            4608-4790           AL161420.10        54341-54523         c
            4791-4904           AL161420.10        52636-52749         c
            4905-5120           AL161420.10        52300-52515         c
            5121-5178           AL161420.10        49823-49880         c
            5179-5285           AL161420.10        47391-47497         c
            5286-5408           AL161420.10        33162-33284         c
            5409-5522           AL161420.10        32345-32458         c
            5523-5669           AL161420.10        30654-30800         c
            5670-5880           AL161420.10        27992-28202         c
            5881-6071           AL161420.10        23281-23471         c
            6072-6172           AL161420.10        20382-20482         c
            6173-6311           AL161420.10        20108-20246         c
            6312-7631           AL161420.10        16422-17741         c
FEATURES             Location/Qualifiers
     source          1..7631
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q32.3"
     gene            1..7631
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /note="dedicator of cytokinesis 9"
                     /db_xref="GeneID:23348"
                     /db_xref="HGNC:HGNC:14132"
                     /db_xref="MIM:607325"
     exon            1..281
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     CDS             156..6434
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /note="isoform 13 is encoded by transcript variant 13;
                     dedicator of cytokinesis protein 9; cdc42 guanine
                     nucleotide exchange factor zizimin-1"
                     /codon_start=1
                     /product="dedicator of cytokinesis protein 9 isoform 13"
                     /protein_id="NP_001353612.1"
                     /db_xref="CCDS:CCDS91828.1"
                     /db_xref="GeneID:23348"
                     /db_xref="HGNC:HGNC:14132"
                     /db_xref="MIM:607325"
                     /translation="MQADKCRTSSRSVKKELVIESPLQYKDAAQGEVEAESPGPVPAK
                     PKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE
                     EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDK
                     DEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKD
                     EKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILN
                     KILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESR
                     VKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTN
                     VEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGIL
                     HEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLK
                     NAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLA
                     DFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEF
                     VPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKC
                     IYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSS
                     KGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGP
                     EIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLH
                     AMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYV
                     KYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQ
                     HLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIK
                     RCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLPMPFGK
                     GRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLKNLLIKH
                     SFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDESLALPA
                     VNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRGSLISTDSGN
                     SLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALFT
                     YWNKASTSELMDFFTISEVCLHQFQYMGKRYIARNQEGLGPIVHDRKSQTLPVSRNRT
                     GMMHARLQQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLSLFTLA
                     FKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRA
                     DMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQ
                     LIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKE
                     HENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVA
                     EYLTRKGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWK
                     AERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRV
                     AFFGQGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPK
                     DLDSKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQ
                     CKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDM
                     IKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQAL
                     AVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQICPLEEKTSVLPNSLHIFNAIS
                     GTPTSTMVHGMTSSSSVV"
     exon            282..398
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            399..488
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            489..571
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            572..641
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            642..737
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            738..872
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            873..1047
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1115
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            1116..1190
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1331
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            1332..1535
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            1536..1658
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            1659..1741
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            1742..1864
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            1865..1944
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            1945..2132
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            2133..2198
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            2199..2291
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            2292..2415
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            2416..2537
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            2538..2624
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            2625..2714
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            2715..2830
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            2831..2900
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            2901..3026
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            3027..3098
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            3099..3245
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            3246..3329
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            3330..3441
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            3442..3620
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            3621..3734
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            3735..3852
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            3853..3986
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            3987..4101
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            4102..4168
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            4169..4216
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            4217..4353
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            4354..4469
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            4470..4607
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            4608..4790
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            4791..4904
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            4905..5120
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            5121..5178
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            5179..5285
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            5286..5408
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            5409..5522
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            5523..5669
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            5670..5880
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            5881..6071
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            6072..6172
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            6173..6311
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            6312..7631
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7550..7555
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /note="hexamer: ATTAAA"
     polyA_site      7571
                     /gene="DOCK9"
                     /gene_synonym="ZIZ1; ZIZIMIN1"
                     /note="major polyA site"
ORIGIN      
        1 aggctctgca gacccagcca gcggggctga ccacttgtgc ctgggaagcc agtttccttt
       61 ccttccttgg accactggca tgcctgtgcc ttgcacggcc agggactcgc agctgttcca
      121 gttgcagact ttctgacttg cgttttcagc cgagaatgca ggctgataaa tgcaggacaa
      181 gtagtagaag tgtcaaaaag gaactggtga ttgagtcccc cctgcaatac aaggatgcag
      241 ctcagggcga agtggaagca gagagcccgg gccctgtgcc ggcaaagcca aagctaattg
      301 agccactcga ctatgaaaat gtcatcgtcc agaagaagac tcagatcctg aacgactgtt
      361 tacgggagat gctgctcttc ccttacgatg actttcagac ggccatcctg agacgacagg
      421 gtcgatacat atgctcaaca gtgcctgcga aggcggaaga ggaagcacag agcttgtttg
      481 ttacagagtg catcaaaacc tataactctg actggcatct tgtgaactat aaatatgaag
      541 attactcagg agagtttcga cagcttccga acaaagtggt caagttggat aaacttccag
      601 ttcatgtcta tgaagttgac gaggaggtcg acaaagatga ggatgctgcc tcccttggtt
      661 cccagaaggg tgggatcacc aagcatggct ggctgtacaa aggcaacatg aacagtgcca
      721 tcagcgtgac catgaggtca tttaagagac gatttttcca cctgattcaa cttggcgatg
      781 gatcctataa tttgaatttt tataaagatg aaaagatctc caaagaacca aaaggatcaa
      841 tatttctgga ttcctgtatg ggtgtcgttc agaacaacaa agtcaggcgt tttgcttttg
      901 agctcaagat gcaggacaaa agtagttatc tcttggcagc agacagtgaa gtggaaatgg
      961 aagaatggat cacaattcta aataagatcc tccagctcaa ctttgaagct gcaatgcaag
     1021 aaaagcgaaa tggcgactct cacgaagatg atgaacaaag caaattggaa ggttctggtt
     1081 ccggtttaga tagctacctg ccggaacttg ccaagagtgc aagagaagca gaaatcaaac
     1141 tgaaaagtga aagcagagtc aaactttttt atttggaccc agatgcccag aagcttgact
     1201 tctcatcagc tgagccagaa gtgaagtcat ttgaagagaa gtttggaaaa aggatccttg
     1261 tcaagtgcaa tgatttatct ttcaatttgc aatgctgtgt tgccgaaaat gaagaaggac
     1321 ccactacaaa tgttgaacct ttctttgtta ctctatccct gtttgacata aaatacaacc
     1381 ggaagatttc tgccgatttc cacgtagacc tgaaccattt ctcagtgagg caaatgctcg
     1441 ccaccacgtc cccggcgctg atgaatggca gtgggcagag cccatctgtc ctcaagggca
     1501 tccttcatga agccgccatg cagtatccga agcagggaat attttcagtc acttgtcctc
     1561 atccagatat atttcttgtg gccagaattg aaaaagtcct tcaggggagc atcacacatt
     1621 gcgctgagcc atatatgaaa agttcagact cttctaaggt ggcccagaag gtgctgaaga
     1681 atgccaagca ggcatgccaa agactaggac agtatagaat gccatttgct tgggcagcaa
     1741 ggacattgtt taaggatgca tctggaaatc ttgacaaaaa tgccagattt tctgccatct
     1801 acaggcaaga cagcaataag ctatccaatg atgacatgct caagttactt gcagactttc
     1861 ggaaacctga gaagatggct aagctcccag tgattttagg caatctagac attacaattg
     1921 ataatgtttc ctcagacttc cctaattatg ttaattcatc atacattccc acaaaacaat
     1981 ttgaaacctg cagtaaaact cccatcacgt ttgaagtgga ggaatttgtg ccctgcatac
     2041 caaaacacac tcagccttac accatctaca ccaatcacct ttacgtttat cctaagtact
     2101 tgaaatacga cagtcagaag tcttttgcca aggctagaaa tattgcgatt tgcattgaat
     2161 tcaaagattc agatgaggaa gactctcagc cccttaagtg catttatggc agacctggtg
     2221 ggccagtttt cacaagaagc gcctttgctg cagttttaca ccatcaccaa aacccagaat
     2281 tttatgatga gattaaaata gagttgccca ctcagctgca tgaaaagcac cacctgttgc
     2341 tcacattctt ccatgtcagc tgtgacaact caagtaaagg aagcacgaag aagagggatg
     2401 tcgttgaaac ccaagttggc tactcctggc ttcccctcct gaaagacgga agggtggtga
     2461 caagcgagca gcacatcccg gtctcggcga accttccttc gggctatctt ggctaccagg
     2521 agcttgggat gggcaggcat tatggtccgg aaattaaatg ggtagatgga ggcaagccac
     2581 tgctgaaaat ttccactcat ctggtttcta cagtgtatac tcaggatcag catttacata
     2641 attttttcca gtactgtcag aaaaccgaat ctggagccca agccttagga aacgaacttg
     2701 taaagtacct taagagtctg catgcgatgg aaggccacgt gatgatcgcc ttcttgccca
     2761 ctatcctaaa ccagctgttc cgagtcctca ccagagccac acaggaagaa gtcgcggtta
     2821 acgtgactcg ggtcattatt catgtggttg cccagtgcca tgaggaagga ttggagagcc
     2881 acttgaggtc atatgttaag tacgcgtata aggctgagcc atatgttgcc tctgaataca
     2941 agacagtgca tgaagaactg accaaatcca tgaccacgat tctcaagcct tctgccgatt
     3001 tcctcaccag caacaaacta ctgaagtact catggttttt ctttgatgta ctgatcaaat
     3061 ctatggctca gcatttgata gagaactcca aagttaagtt gctgcgaaac cagagatttc
     3121 ctgcatccta tcatcatgca gtggaaaccg ttgtaaatat gctgatgcca cacatcactc
     3181 agaagtttcg agataatcca gaggcatcta agaacgcgaa tcatagcctt gctgtcttca
     3241 tcaagagatg tttcaccttc atggacaggg gctttgtctt caagcagatc aacaactaca
     3301 ttagctgttt tgctcctgga gacccaaaga ccctctttga atacaagttt gaatttctcc
     3361 gtgtagtgtg caaccatgaa cattatattc cgttgaactt accaatgcca tttggaaaag
     3421 gcaggattca aagataccaa gacctccagc ttgactactc attaacagat gagttctgca
     3481 gaaaccactt cttggtggga ctgttactga gggaggtggg gacagccctc caggagttcc
     3541 gggaggtccg tctgatcgcc atcagtgtgc tcaagaacct gctgataaag cattcttttg
     3601 atgacagata tgcttcaagg agccatcagg caaggatagc caccctctac ctgcctctgt
     3661 ttggtctgct gattgaaaac gtccagcgga tcaatgtgag ggatgtgtca cccttccctg
     3721 tgaacgcggg catgactgtg aaggatgaat ccctggctct accagctgtg aatccgctgg
     3781 tgacgccgca gaagggaagc accctggaca acagcctgca caaggacctg ctgggcgcca
     3841 tctccggcat tgcttctcca tatacaacct caactccaaa catcaacagt gtgagaaatg
     3901 ctgattcgag aggatctctc ataagcacag attcgggtaa cagccttcca gaaaggaata
     3961 gtgagaagag caattccctg gataagcacc aacaaagtag cacattggga aattccgtgg
     4021 ttcgctgtga taaacttgac cagtctgaga ttaagagcct actgatgtgt ttcctctaca
     4081 tcttaaagag catgtctgat gatgctttgt ttacatattg gaacaaggct tcaacatctg
     4141 aacttatgga tttttttaca atatctgaag tctgcctgca ccagttccag tacatgggga
     4201 agcgatacat agccaggaac caggaggggt tgggacccat agttcatgat cgaaagtctc
     4261 agacattgcc tgtttcccgt aacagaacag gaatgatgca tgccagattg cagcagctgg
     4321 gcagcctgga taactctctc acttttaacc acagctatgg ccactcggac gcagatgttc
     4381 tgcaccagtc attacttgaa gccaacattg ctactgaggt ttgcctgaca gctctggaca
     4441 cgctttctct atttacattg gcgtttaaga accagctcct ggccgaccat ggacataatc
     4501 ctctcatgaa aaaagttttt gatgtctacc tgtgttttct tcaaaaacat cagtctgaaa
     4561 cggctttaaa aaatgtcttc actgccttaa ggtccttaat ttataagttt ccctcaacat
     4621 tctatgaagg gagagcggac atgtgtgcgg ctctgtgtta cgagattctc aagtgctgta
     4681 actccaagct gagctccatc aggacggagg cctcccagct gctctacttc ctgatgagga
     4741 acaactttga ttacactgga aagaagtcct ttgtccggac acatttgcaa gtcatcatat
     4801 ctgtcagcca gctgatagca gacgttgttg gcattggggg aaccagattc cagcagtccc
     4861 tgtccatcat caacaactgt gccaacagtg accggcttat taagcacacc agcttctcct
     4921 ctgatgtgaa ggacttaacc aaaaggatac gcacggtgct aatggccacc gcccagatga
     4981 aggagcatga gaacgaccca gagatgctgg tggacctcca gtacagcctg gccaaatcct
     5041 atgccagcac gcccgagctc aggaagacgt ggctcgacag catggccagg atccatgtca
     5101 aaaatggcga tctctcagag gcagcaatgt gctatgtcca cgtaacagcc ctagtggcag
     5161 aatatctcac acggaaaggc gtgtttagac aaggatgcac cgccttcagg gtcattaccc
     5221 caaacatcga cgaggaggcc tccatgatgg aagacgtggg gatgcaggat gtccatttca
     5281 acgaggatgt gctgatggag ctccttgagc agtgcgcaga tggactctgg aaagccgagc
     5341 gctacgagct catcgccgac atctacaaac ttatcatccc catttatgag aagcggaggg
     5401 attttgagag gctggcccat ctgtatgaca cgctgcaccg ggcctacagc aaagtgaccg
     5461 aggtcatgca ctcgggccgc aggcttctgg ggacctactt ccgggtagcc ttcttcgggc
     5521 agggattctt tgaagatgaa gatggaaagg agtatattta caaggaaccc aaactcacac
     5581 cgctgtcgga aatttctcag agactcctta aactgtactc ggataaattt ggttctgaaa
     5641 atgtcaaaat gatacaggat tctggcaagg tcaaccctaa ggatctggat tctaagtatg
     5701 catacatcca ggtgactcac gtcatcccct tctttgacga aaaagagttg caagaaagga
     5761 aaacagagtt tgagagatcc cacaacatcc gccgcttcat gtttgagatg ccatttacgc
     5821 agaccgggaa gaggcagggc ggggtggaag agcagtgcaa acggcgcacc atcctgacag
     5881 ccatacactg cttcccttat gtgaagaagc gcatccctgt catgtaccag caccacactg
     5941 acctgaaccc catcgaggtg gccattgacg agatgagtaa gaaggtggcg gagctccggc
     6001 agctgtgctc ctcggccgag gtggacatga tcaaactgca gctcaaactc cagggcagcg
     6061 tgagtgttca ggtcaatgct ggcccactag catatgcgcg agctttctta gatgatacaa
     6121 acacaaagcg atatcctgac aataaagtga agctgcttaa ggaagttttc aggcaatttg
     6181 tggaagcttg cggtcaagcc ttagcggtaa acgaacgtct gattaaagaa gaccagctcg
     6241 agtatcagga agaaatgaaa gccaactaca gggaaatggc gaaggagctt tctgaaatca
     6301 tgcatgagca gatctgcccc ctggaggaga agacgagcgt cttaccgaat tcccttcaca
     6361 tcttcaacgc catcagtggg actccaacaa gcacaatggt tcacgggatg accagctcgt
     6421 cttcggtcgt gtgattacat ctcatggccc gtgtgtgggg acttgctttg tcatttgcaa
     6481 actcaggatg ctttccaaag ccaatcactg gggagaccga gcacagggag gaccaagggg
     6541 aaggggagag aaaggaaata aagaacaacg ttatttctta acagactttc tataggagtt
     6601 gtaagaaggt gcacatattt ttttaaatct cactggcaat attcaaagtt ttcattgtgt
     6661 cttaacaaag gtgtggtaga cactcttgag ctggacttag attttattct tccttgcaga
     6721 gtagtgttag aatagatggc ctacagaaaa aaaaggttct gggatctaca tggcagggag
     6781 ggctgcactg acattgatgc ctgggggacc ttttgcctcg aggctgagct ggaaaatctt
     6841 gaaaatattt tttttttcct gtggcacatt caggttgaat acaagaacta tttttgtgac
     6901 tagtttttga tgacctaagg gaactgacca ttgtaatttt tgtaccagtg aaccaggaga
     6961 tttagtgctt ttatattcat ttccttgcat ttaagaaaat atgaaagctt aaggaattat
     7021 gtgagcttaa aactagtcaa gcagtttaga accaaaggcc tatattaata accgcaacta
     7081 tgctgaaaag tacaaagtag tacagtatat tgttatgtac atatcattgt taatacagtc
     7141 ctggcattct gtacatatat gtattacatt tctacatttt taatactcac atgggcttat
     7201 gcattaagtt taattgtgat aaatttgtgc tgttccagta tatgcaatac actttaatgt
     7261 tttattcttg tacataaaaa tgtgcaatat ggagatgtat acagtcttta ctatattagg
     7321 tttataaaca gttttaagaa tttcatcctt ttgccaaaat ggtggagtat gtaattggta
     7381 aatcataaat cctgtggtga atggtggtgt actttaaagc tgtcaccatg ttatattttc
     7441 ttttaagact ttaatttagt aattttatat ttgggaaaat aaaggttttt aattttattt
     7501 aactggaatc actgccctgc tgtaattaaa cattctgtac cacatctgta ttaaaaagac
     7561 attgctgacc atttggggtg gctgctgggt gtttattgtt cagcagtcct aagggaacag
     7621 gataccaaaa t
//
