LOCUS       XM_047444932            7174 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens dedicator of cytokinesis 10 (DOCK10),
            transcript variant X17, mRNA.
ACCESSION   XM_047444932
VERSION     XM_047444932.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7174
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..7174
                     /gene="DOCK10"
                     /gene_synonym="DRIP2; Nbla10300; ZIZ3"
                     /note="dedicator of cytokinesis 10; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 41 ESTs, 315 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 8 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:55619"
                     /db_xref="HGNC:HGNC:23479"
                     /db_xref="MIM:611518"
     CDS             99..6488
                     /gene="DOCK10"
                     /gene_synonym="DRIP2; Nbla10300; ZIZ3"
                     /codon_start=1
                     /product="dedicator of cytokinesis protein 10 isoform X17"
                     /protein_id="XP_047300888.1"
                     /db_xref="GeneID:55619"
                     /db_xref="HGNC:HGNC:23479"
                     /db_xref="MIM:611518"
                     /translation="MSFRGKVFKREPSEFWKKRRTVRRVNQEEIHRFSSQEKPRLLEP
                     LDYETVIEELEKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLL
                     VKEACKFYSSQWHVVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTT
                     SHSSSKGGGGAGGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMN
                     FYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWI
                     HTLNRILQISPEGPLQGRRSTELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKY
                     LTETEDTVKTTRNMERLNLFSLDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIIC
                     KALNSNLQGCVTENENDPITNIEPFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLL
                     GASVALENGNIDTITPRQSEEPHIKGLPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKV
                     LMGNIASGAEPYIKNPDSNKYAQKILKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNV
                     DRDSRFSPLFRQESSKISTEDLVKLVSDYRRADRISKMQTIPGSLDIAVDNVPLEHPN
                     CVTSSFIPVKPFNMMAQTEPTVEVEEFVYDSTKYCRPYRVYKNQIYIYPKHLKYDSQK
                     CFNKARNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTSAAYTAVLHHSQNPDFSDEV
                     KIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALETSVGYAWLPLMKHDQIASQE
                     YNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNA
                     FFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIMSFLPIILNQLFKVLVQNEEDE
                     ITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFKTRACKERTVHEELAKNVTGLLKSN
                     DSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQRCFTFMDRGYVFKMVNNYISMFSS
                     GDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHASDMPEYSV
                     TNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREPRKQAQI
                     ASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHANSVD
                     TSFSKDVLNSIAVNHADSRASLASLDSNPSTNEKSSEKTDNCEKIPRPLSLIGSTLRF
                     DKLDQAETRSLLMCFLHIMKTISYETLIAYWQRAPSPEVSDFFSILDVCLQNFRYLGK
                     RNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHSTSSHEGHKQHRSQTLP
                     IIRGKNALSNPKLLQMLDNTMTSNSNEIDIVHHVDTEANIATEVCLTILDLLSLFTQT
                     HQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATALKHVFASLRLFVCKFPSAFFQGPA
                     DLCGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKNFEFNKQKSIVRSHLQLIKAVSQ
                     LIADAGIGGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLMATAQMKEH
                     EKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHIAALIAE
                     YLKRKGYWKVEKICTASLLSEDTHPCDSNSLLTTPSGGSMFSMGWPAFLSITPNIKEE
                     GAMKEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKK
                     LSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGL
                     SEISQRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDR
                     KTDFEMHHNINRFVFETPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVISQS
                     STELNPIEVAIDEMSKKVSELNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAF
                     LEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDML
                     SELSTVMNEQLCRGPCLYSFCSSVSSISLSTVSKSDYGQGRPVKARSGPNLHSSN"
ORIGIN      
        1 agaagaaaga tttgttcagc ctggtgacgc ttcagaagag aagagtttaa cgacattgat
       61 attttgaaat attttgtgac tcaaattata gcaatacgat gagttttcga gggaaggttt
      121 ttaaacggga gcccagtgaa ttttggaaga agagacgaac tgtgaggaga gtaaaccaag
      181 aagaaatcca cagatttagt tctcaagaaa agcctaggct tctcgagcct ttggattatg
      241 agactgtcat tgaagaactt gaaaagacct accggaatga tcctcttcaa gatctcttgt
      301 tcttccccag tgatgacttt tcagcagcca cagtttcctg ggatatccgc acgttgtact
      361 caacagtacc tgaagatgca gagcacaagg cagaaaattt actggttaag gaggcttgta
      421 aattttatag ttcccagtgg catgtggtaa actacaaata tgaacaatat tctggagaca
      481 ttcgacagct accccgagca gaatacaaac cagagaagct tccttcacat tcctttgaga
      541 ttgaccatga agatgctgat aaggatgaag ataccacttc ccactcgtct tccaaggggg
      601 gtggaggagc gggaggaact ggtgttttca agtccggctg gctctacaag gggaatttta
      661 acagcaccgt gaacaacacc gttactgttc ggtcattcaa aaagcgctac ttccagctga
      721 ctcagttacc agataactcc tacattatga acttttacaa agatgagaaa atatccaaag
      781 aacccaaagg atgcatcttt ttggattcct gtacaggagt ggtgcagaat aacagactaa
      841 gaaaatatgc ctttgaattg aaaatgaatg atctgaccta ttttgtgctg gcagctgaaa
      901 cagagtcaga tatggatgaa tggatccaca ccctcaaccg cattctgcaa atcagtcctg
      961 aggggcccct ccaagggagg aggagcacag agctcactga tctgggtctg gattcgctgg
     1021 ataattctgt aacttgtgaa tgcacgccag aggaaacaga ttcttcagag aacaacctac
     1081 acgcagactt tgcaaagtac ctcacagaaa cagaagatac tgtaaaaaca actcgaaaca
     1141 tggagaggct aaatctgttc tctctagatc cagacataga taccttgaaa cttcaaaaaa
     1201 aagatctctt ggaacctgag tctgtgatca aaccatttga agaaaaagct gccaagagaa
     1261 tcatgatcat ctgtaaagcc ctcaactcaa atcttcaggg atgtgttacg gagaatgaaa
     1321 atgatccgat aacgaatatt gagccttttt ttgtgagtgt ggcactttat gacctcagag
     1381 acagcaggaa gatttctgct gattttcatg tggatctaaa ccatgctgct gtcagacaga
     1441 tgctcttggg ggcttctgtg gctttggaaa atggcaacat cgacaccatc actccaagac
     1501 aatcagaaga acctcacatc aagggacttc cagaggaatg gctaaaattt ccaaagcagg
     1561 ctgtattttc tgtaagcaat ccacattctg aaattgtttt ggtggccaaa atcgaaaaag
     1621 tcttgatggg aaacattgca agtggtgccg aaccttatat taagaaccca gactccaaca
     1681 agtatgcaca aaagatacta aaatccaaca gacaattctg cagcaaattg ggaaaatacc
     1741 gtatgccttt tgcttgggca gtaagatcag tatttaagga caaccaggga aatgtggaca
     1801 gagactcaag attttcacca ttgtttagac aagaaagtag caagatttca actgaggacc
     1861 tagttaaact agtatcagat tatagaaggg ccgacagaat aagcaaaatg cagaccattc
     1921 ctggaagcct ggatattgct gttgacaacg ttcccttgga gcatccaaat tgtgtaacat
     1981 cgtcctttat ccctgtcaag cctttcaaca tgatggctca aacagaaccc acagtggagg
     2041 tggaagaatt tgtttacgat tcaacaaagt attgtcggcc ttacagagta tataaaaatc
     2101 aaatttatat ttaccccaaa cacctcaagt atgatagcca gaaatgcttc aacaaggcac
     2161 ggaatataac tgtgtgcatt gaattcaaaa attcagatga agaaagtgcc aagcccctga
     2221 agtgtattta tggaaaacct ggagggcccc tcttcacctc agccgcctac acagcagttc
     2281 tgcaccactc tcagaatccg gatttctcag atgaggtgaa aattgagcta ccaacacaac
     2341 tccatgagaa acaccatatt ttgttttctt tttatcacgt cacctgtgac atcaatgcaa
     2401 aagctaatgc caaaaagaag gaggctctgg aaacgtcagt tggatatgct tggcttcctc
     2461 tgatgaaaca cgatcagata gcttctcaag agtacaacat cccaatagca acaagtctgc
     2521 ctcctaatta tttaagcttt caagattctg caagtggaaa gcatggtggg agtgacatta
     2581 aatgggttga tggtggcaaa ccacttttca aagtgtcgac atttgttgta tcaacagtaa
     2641 atactcagga tccacatgtg aatgcatttt tccaagagtg ccaaaaaaga gagaaagata
     2701 tgtctcagtc acctacctca aatttcatcc gctcttgtaa gaacttattg aatgtggaaa
     2761 agattcatgc aatcatgagt tttctgccta taattttgaa tcagctcttc aaagttctgg
     2821 tacagaatga ggaagatgaa ataactacaa ctgtcaccag ggttctgacc gacattgtgg
     2881 ccaagtgcca tgaggagcag ctggatcatt ctgtccagtc atatattaag ttcgtgttca
     2941 agaccagggc atgcaaggag aggactgtac atgaggaact ggctaaaaat gtgactggtc
     3001 ttttgaaatc aaatgactca acaacagtaa agcatgtcct aaagcattcc tggttcttct
     3061 ttgcaattat cctaaaatcg atggcacagc acttgattga cacaaataaa atccagcgct
     3121 gctttacatt tatggaccga gggtatgtgt ttaagatggt caacaattac atcagcatgt
     3181 tctcctccgg tgaccttaag accttgtgcc agtataaatt tgattttctt caagaagtat
     3241 gtcaacatga acactttatc cctttgtgtc tgcccataag atcagcaaac attccagatc
     3301 ctttgacacc ttcagaatcg actcaagagt tacatgcatc agatatgcct gaatattcag
     3361 tcacaaatga attttgtcgc aaacacttct taatcggaat tctgctccga gaagttggct
     3421 ttgccctgca ggaagaccaa gatgtcagac acttagcttt agctgtccta aaaaatctaa
     3481 tggctaagca ttcatttgat gatcgataca gagagccaag aaagcaggcc cagatagcaa
     3541 gtttatacat gcccctgtac ggcatgctcc tggacaatat gccaaggatt tatctgaagg
     3601 acctgtatcc ttttactgtc aatacatcta atcaggggtc tagagatgat ctaagcacca
     3661 atggaggatt tcaaagccag acagctatca aacatgcaaa ctctgtggat acatcatttt
     3721 ctaaagatgt tttaaattcc atagcagtaa accatgctga ctccagagca tctttagcaa
     3781 gtcttgactc caatccaagt accaatgaga agagcagtga gaagacggac aactgtgaaa
     3841 agatcccaag acccttgtct ttgattggct caactcttcg atttgacaag ttagatcaag
     3901 cagaaaccag gagtctcctg atgtgttttc ttcacattat gaaaacgatt tcgtacgaga
     3961 ctctgattgc ctactggcag agagctccca gcccagaggt gtccgacttc ttcagcatct
     4021 tggacgtttg tcttcaaaat ttcagatacc taggaaaacg caacataata agaaaaattg
     4081 ctgctgcatt taaatttgtg cagtccaccc agaacaatgg aactctcaaa ggatccaatc
     4141 cttcctgcca gacatcaggt ctcttgtcac aatggatgca ctccacttcc agtcatgaag
     4201 gccataagca gcacagatca caaactttac ctataattcg aggcaaaaat gcactttcta
     4261 accccaaact cttacagatg ttagacaata ccatgaccag caactccaat gaaatagaca
     4321 tcgtgcatca tgtagacact gaggccaata tagctacgga ggtttgcctc actattctgg
     4381 acctgttatc cctcttcaca cagactcatc agagacaact ccaacaatgt gactgtcaaa
     4441 attcattgat gaaaagggtc tttgatacct acatgctctt tttccaagtc aatcagtcag
     4501 ccacagcgct gaagcatgtg tttgcctcct tgagactgtt tgtatgcaag tttccttcag
     4561 cgttctttca agggcctgct gacctctgtg gatcattctg ttacgaagtc ctaaaatgct
     4621 gtaaccacag gtcacggtca actcagacag aagcctcagc ccttctgtac tttttcatga
     4681 ggaagaattt tgaatttaac aagcagaagt caattgtccg gtcccactta caactcatca
     4741 aagctgtgag ccagttaata gccgatgctg ggattggagg ctctcggttt caacattcgc
     4801 ttgcaattac caataatttc gccaatggag ataagcaaat gaaaaacagc aatttcccag
     4861 cagaggtgaa ggacctgact aagcgtataa ggactgtttt gatggccaca gctcagatga
     4921 aggagcacga gaaggacccc gagatgctgg tggatctcca gtacagcctg gcaaactcct
     4981 acgcaagcac tcctgaacta cgcaggacct ggctggaaag tatggccaag attcatgcca
     5041 gaaacggaga tttatctgag gctgccatgt gttacatcca tattgctgct ctcattgcag
     5101 agtatctgaa aagaaagggt tactggaaag tggaaaagat ttgcacagca tccctgctct
     5161 cggaggatac ccacccctgt gatagcaact cattactaac aactcccagt ggaggaagca
     5221 tgttctctat gggatggcca gcttttttga gcattacacc aaacattaag gaagaaggag
     5281 cgatgaaaga ggattctgga atgcaagata caccatacaa tgagaatatc ctggtggagc
     5341 agctatacat gtgtgtggag tttctctgga agtctgagcg atatgaactc attgctgatg
     5401 tcaacaagcc catcattgct gtctttgaga aacaacgaga cttcaaaaaa ttgtcagatc
     5461 tctactacga cattcatcgg tcatatctga aagtggcaga ggtggtgaat tcggagaagc
     5521 ggctgtttgg tcgctactat cgtgtggcat tttatgggca gggctttttt gaagaagaag
     5581 aaggtaaaga gtatatttat aaagagccta agctgacagg tctgtccgag atttcccaaa
     5641 gattactcaa gctctatgca gataaatttg gagcagacaa tgtgaagata atccaggatt
     5701 ccaacaaggt aaaccccaag gatttggacc ccaaatatgc ctacatccag gtgacctatg
     5761 tgacgccgtt ctttgaggaa aaggaaatcg aagaccggaa gacagatttc gaaatgcacc
     5821 acaacatcaa ccgctttgtc ttcgagacac ccttcacgct gtcgggcaag aagcacggtg
     5881 gggtggcgga gcagtgcaag cggcggacga tcctgacaac gagtcacctg ttcccctacg
     5941 tgaagaagag aatacaagta attagccaat cgagcacaga actgaatcca attgaagtgg
     6001 caattgacga gatgtccaag aaggtttctg agcttaatca gctttgcaca atggaagaag
     6061 tggacatgat cagactgcag ctcaaactgc aaggaagtgt cagcgtgaag gttaatgctg
     6121 ggccaatggc ctatgcacga gcttttcttg aagaaaccaa tgcaaagaag taccctgaca
     6181 accaagtaaa gcttttgaag gagatcttca ggcaatttgc agatgcatgt gggcaggccc
     6241 ttgacgtgaa tgagcgcctc atcaaagagg accagctgga gtaccaggaa gaactgaggt
     6301 cccactacaa ggacatgctc agcgaactct ccacagtcat gaatgagcag ctctgtcgag
     6361 gtccgtgttt atacagcttc tgttcctctg tgtctagtat ttccctcagt actgtaagca
     6421 aaagtgatta cgggcaggga cgacctgtca aagcgcggag tggaccaaac ctgcactcga
     6481 gtaattagca aagcaactcc ggccctaccc acggtctcca tctcatctag tgctgaagtc
     6541 tgagggctct gcagcatcag acccacctct aagagaactt tctgaatttg cagctaatct
     6601 cggggaagag aaagataggt ttaatttatt tgaagttttc atggtgttaa tatttttgtt
     6661 tacctcgcta gcttcagaat tttgccaacc tctgaatttg cacattttgt ataatttttt
     6721 tttctttgag cagtgttgat caagccaggt tgaatatttg ccatgaaatt ccagtgaatg
     6781 tgtagctcaa atgcaaaccc taagtttgct gtcagttatt gtatggtcag taccccagtc
     6841 ctagtacaca tattttaaag gttaaagtga atgtttttgt aacatttaag catatttcag
     6901 atgtaaataa aagattgtaa aatatacggt ttttaccaaa tttaaaagat cctttttagt
     6961 taatactatg acagtactaa aaatatatga ataacatttc agataccatt atattaaaat
     7021 atttgtgtat gtgtacaaaa gcgttgataa atactaatct ttaaagtttg tggagttcct
     7081 ttatttgtaa tatatgtgct cttaaaagca atgggatgtg aaattatgaa agtattttat
     7141 tgttcataga aataaaaaac acagttactt tgca
//
