LOCUS       XM_047444919            7263 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens dedicator of cytokinesis 10 (DOCK10),
            transcript variant X4, mRNA.
ACCESSION   XM_047444919
VERSION     XM_047444919.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7263
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..7263
                     /gene="DOCK10"
                     /gene_synonym="DRIP2; Nbla10300; ZIZ3"
                     /note="dedicator of cytokinesis 10; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 6
                     mRNAs, 41 ESTs, 456 long SRA reads, 4 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 50 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:55619"
                     /db_xref="HGNC:HGNC:23479"
                     /db_xref="MIM:611518"
     CDS             60..6632
                     /gene="DOCK10"
                     /gene_synonym="DRIP2; Nbla10300; ZIZ3"
                     /codon_start=1
                     /product="dedicator of cytokinesis protein 10 isoform X4"
                     /protein_id="XP_047300875.1"
                     /db_xref="GeneID:55619"
                     /db_xref="HGNC:HGNC:23479"
                     /db_xref="MIM:611518"
                     /translation="MGCTASIVLLQAFRSVVQRSCPHICRRRQEEPSHEILPLESDDE
                     MNRPRTLIIMQEKPRLLEPLDYETVIEELEKTYRNDPLQDLLFFPSDDFSAATVSWDI
                     RTLYSTVPEDAEHKAENLLVKEACKFYSSQWHVVNYKYEQYSGDIRQLPRAEYKPEKL
                     PSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGTGVFKSGWLYKGNFNSTVNNTVTVRS
                     FKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMN
                     DLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGRRSTELTDLGLDSLDNSVTCEC
                     TPEETDSSENNLHADFAKYLTETEDTVKTTRNMERLNLFSLDPDIDTLKLQKKDLLEP
                     ESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNIEPFFVSVALYDLRDSRK
                     ISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHIKGLPEEWLKFPKQAV
                     FSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKILKSNRQFCSKLGKY
                     RMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVSDYRRADRISKMQ
                     TIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVYDSTKYCRPYR
                     VYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTS
                     AAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALET
                     SVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGGKPLF
                     KVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIMSF
                     LPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFKTRACK
                     ERTVHEELAKNVTGLLKSNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPRPQ
                     RFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKM
                     VNNYISMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQEL
                     HASDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDR
                     YREPRKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQ
                     TAIKHANSVDTSFSKDVLNSIAVNHADSRASLASLDSNPSTNEKSSEKTDNCEKIPRP
                     LSLIGSTLRFDKLDQAETRSLLMCFLHIMKTISYETLIAYWQRAPSPEVSDFFSILDV
                     CLQNFRYLGKRNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHSTSSHEG
                     HKQHRSQTLPIIRGKNALSNPKLLQMLDNTMTSNSNEIDIVHHVDTEANIATEVCLTI
                     LDLLSLFTQTHQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATALKHVFASLRLFVCK
                     FPSAFFQGPADLCGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKNFEFNKQKSIVRS
                     HLQLIKAVSQLIADAGIGGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTV
                     LMATAQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMC
                     YIHIAALIAEYLKRKGYWKVEKICTASLLSEDTHPCDSNSLLTTPSGGSMFSMGWPAF
                     LSITPNIKEEGAMKEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIA
                     VFEKQRDFKKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEY
                     IYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTP
                     FFEEKEIEDRKTDFEMHHNINRFVFETPFTLSGKKHGGVAEQCKRRTILTTSHLFPYV
                     KKRIQVISQSSTELNPIEVAIDEMSKKVSELNQLCTMEEVDMIRLQLKLQGSVSVKVN
                     AGPMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQE
                     ELRSHYKDMLSELSTVMNEQITGRDDLSKRGVDQTCTRVISKATPALPTVSISSSAEV
                     "
ORIGIN      
        1 actgttttgc aaacatagca tcaacataga agttattttg taggctccag gatgcagcga
       61 tgggctgcac tgccagcatt gttctgcttc aagcttttcg ttctgtggtc cagaggagct
      121 gtccacacat ttgtagacga cgccaagagg aaccatccca cgaaattttg cctctggaaa
      181 gtgacgatga aatgaataga cccagaaccc tcatcataat gcaagaaaag cctaggcttc
      241 tcgagccttt ggattatgag actgtcattg aagaacttga aaagacctac cggaatgatc
      301 ctcttcaaga tctcttgttc ttccccagtg atgacttttc agcagccaca gtttcctggg
      361 atatccgcac gttgtactca acagtacctg aagatgcaga gcacaaggca gaaaatttac
      421 tggttaagga ggcttgtaaa ttttatagtt cccagtggca tgtggtaaac tacaaatatg
      481 aacaatattc tggagacatt cgacagctac cccgagcaga atacaaacca gagaagcttc
      541 cttcacattc ctttgagatt gaccatgaag atgctgataa ggatgaagat accacttccc
      601 actcgtcttc caaggggggt ggaggagcgg gaggaactgg tgttttcaag tccggctggc
      661 tctacaaggg gaattttaac agcaccgtga acaacaccgt tactgttcgg tcattcaaaa
      721 agcgctactt ccagctgact cagttaccag ataactccta cattatgaac ttttacaaag
      781 atgagaaaat atccaaagaa cccaaaggat gcatcttttt ggattcctgt acaggagtgg
      841 tgcagaataa cagactaaga aaatatgcct ttgaattgaa aatgaatgat ctgacctatt
      901 ttgtgctggc agctgaaaca gagtcagata tggatgaatg gatccacacc ctcaaccgca
      961 ttctgcaaat cagtcctgag gggcccctcc aagggaggag gagcacagag ctcactgatc
     1021 tgggtctgga ttcgctggat aattctgtaa cttgtgaatg cacgccagag gaaacagatt
     1081 cttcagagaa caacctacac gcagactttg caaagtacct cacagaaaca gaagatactg
     1141 taaaaacaac tcgaaacatg gagaggctaa atctgttctc tctagatcca gacatagata
     1201 ccttgaaact tcaaaaaaaa gatctcttgg aacctgagtc tgtgatcaaa ccatttgaag
     1261 aaaaagctgc caagagaatc atgatcatct gtaaagccct caactcaaat cttcagggat
     1321 gtgttacgga gaatgaaaat gatccgataa cgaatattga gccttttttt gtgagtgtgg
     1381 cactttatga cctcagagac agcaggaaga tttctgctga ttttcatgtg gatctaaacc
     1441 atgctgctgt cagacagatg ctcttggggg cttctgtggc tttggaaaat ggcaacatcg
     1501 acaccatcac tccaagacaa tcagaagaac ctcacatcaa gggacttcca gaggaatggc
     1561 taaaatttcc aaagcaggct gtattttctg taagcaatcc acattctgaa attgttttgg
     1621 tggccaaaat cgaaaaagtc ttgatgggaa acattgcaag tggtgccgaa ccttatatta
     1681 agaacccaga ctccaacaag tatgcacaaa agatactaaa atccaacaga caattctgca
     1741 gcaaattggg aaaataccgt atgccttttg cttgggcagt aagatcagta tttaaggaca
     1801 accagggaaa tgtggacaga gactcaagat tttcaccatt gtttagacaa gaaagtagca
     1861 agatttcaac tgaggaccta gttaaactag tatcagatta tagaagggcc gacagaataa
     1921 gcaaaatgca gaccattcct ggaagcctgg atattgctgt tgacaacgtt cccttggagc
     1981 atccaaattg tgtaacatcg tcctttatcc ctgtcaagcc tttcaacatg atggctcaaa
     2041 cagaacccac agtggaggtg gaagaatttg tttacgattc aacaaagtat tgtcggcctt
     2101 acagagtata taaaaatcaa atttatattt accccaaaca cctcaagtat gatagccaga
     2161 aatgcttcaa caaggcacgg aatataactg tgtgcattga attcaaaaat tcagatgaag
     2221 aaagtgccaa gcccctgaag tgtatttatg gaaaacctgg agggcccctc ttcacctcag
     2281 ccgcctacac agcagttctg caccactctc agaatccgga tttctcagat gaggtgaaaa
     2341 ttgagctacc aacacaactc catgagaaac accatatttt gttttctttt tatcacgtca
     2401 cctgtgacat caatgcaaaa gctaatgcca aaaagaagga ggctctggaa acgtcagttg
     2461 gatatgcttg gcttcctctg atgaaacacg atcagatagc ttctcaagag tacaacatcc
     2521 caatagcaac aagtctgcct cctaattatt taagctttca agattctgca agtggaaagc
     2581 atggtgggag tgacattaaa tgggttgatg gtggcaaacc acttttcaaa gtgtcgacat
     2641 ttgttgtatc aacagtaaat actcaggatc cacatgtgaa tgcatttttc caagagtgcc
     2701 aaaaaagaga gaaagatatg tctcagtcac ctacctcaaa tttcatccgc tcttgtaaga
     2761 acttattgaa tgtggaaaag attcatgcaa tcatgagttt tctgcctata attttgaatc
     2821 agctcttcaa agttctggta cagaatgagg aagatgaaat aactacaact gtcaccaggg
     2881 ttctgaccga cattgtggcc aagtgccatg aggagcagct ggatcattct gtccagtcat
     2941 atattaagtt cgtgttcaag accagggcat gcaaggagag gactgtacat gaggaactgg
     3001 ctaaaaatgt gactggtctt ttgaaatcaa atgactcaac aacagtaaag catgtcctaa
     3061 agcattcctg gttcttcttt gcaattatcc taaaatcgat ggcacagcac ttgattgaca
     3121 caaataaaat ccagcttccc cggcctcaga gatttcctga atcttaccaa aatgaattgg
     3181 acaatcttgt catggtccta tccgaccatg tgatttggaa atacaaggat gcacttgaag
     3241 aaacaagaag ggcaaaccac agcgttgcca gatttctcaa gcgctgcttt acatttatgg
     3301 accgagggta tgtgtttaag atggtcaaca attacatcag catgttctcc tccggtgacc
     3361 ttaagacctt gtgccagtat aaatttgatt ttcttcaaga agtatgtcaa catgaacact
     3421 ttatcccttt gtgtctgccc ataagatcag caaacattcc agatcctttg acaccttcag
     3481 aatcgactca agagttacat gcatcagata tgcctgaata ttcagtcaca aatgaatttt
     3541 gtcgcaaaca cttcttaatc ggaattctgc tccgagaagt tggctttgcc ctgcaggaag
     3601 accaagatgt cagacactta gctttagctg tcctaaaaaa tctaatggct aagcattcat
     3661 ttgatgatcg atacagagag ccaagaaagc aggcccagat agcaagttta tacatgcccc
     3721 tgtacggcat gctcctggac aatatgccaa ggatttatct gaaggacctg tatcctttta
     3781 ctgtcaatac atctaatcag gggtctagag atgatctaag caccaatgga ggatttcaaa
     3841 gccagacagc tatcaaacat gcaaactctg tggatacatc attttctaaa gatgttttaa
     3901 attccatagc agtaaaccat gctgactcca gagcatcttt agcaagtctt gactccaatc
     3961 caagtaccaa tgagaagagc agtgagaaga cggacaactg tgaaaagatc ccaagaccct
     4021 tgtctttgat tggctcaact cttcgatttg acaagttaga tcaagcagaa accaggagtc
     4081 tcctgatgtg ttttcttcac attatgaaaa cgatttcgta cgagactctg attgcctact
     4141 ggcagagagc tcccagccca gaggtgtccg acttcttcag catcttggac gtttgtcttc
     4201 aaaatttcag atacctagga aaacgcaaca taataagaaa aattgctgct gcatttaaat
     4261 ttgtgcagtc cacccagaac aatggaactc tcaaaggatc caatccttcc tgccagacat
     4321 caggtctctt gtcacaatgg atgcactcca cttccagtca tgaaggccat aagcagcaca
     4381 gatcacaaac tttacctata attcgaggca aaaatgcact ttctaacccc aaactcttac
     4441 agatgttaga caataccatg accagcaact ccaatgaaat agacatcgtg catcatgtag
     4501 acactgaggc caatatagct acggaggttt gcctcactat tctggacctg ttatccctct
     4561 tcacacagac tcatcagaga caactccaac aatgtgactg tcaaaattca ttgatgaaaa
     4621 gggtctttga tacctacatg ctctttttcc aagtcaatca gtcagccaca gcgctgaagc
     4681 atgtgtttgc ctccttgaga ctgtttgtat gcaagtttcc ttcagcgttc tttcaagggc
     4741 ctgctgacct ctgtggatca ttctgttacg aagtcctaaa atgctgtaac cacaggtcac
     4801 ggtcaactca gacagaagcc tcagcccttc tgtacttttt catgaggaag aattttgaat
     4861 ttaacaagca gaagtcaatt gtccggtccc acttacaact catcaaagct gtgagccagt
     4921 taatagccga tgctgggatt ggaggctctc ggtttcaaca ttcgcttgca attaccaata
     4981 atttcgccaa tggagataag caaatgaaaa acagcaattt cccagcagag gtgaaggacc
     5041 tgactaagcg tataaggact gttttgatgg ccacagctca gatgaaggag cacgagaagg
     5101 accccgagat gctggtggat ctccagtaca gcctggcaaa ctcctacgca agcactcctg
     5161 aactacgcag gacctggctg gaaagtatgg ccaagattca tgccagaaac ggagatttat
     5221 ctgaggctgc catgtgttac atccatattg ctgctctcat tgcagagtat ctgaaaagaa
     5281 agggttactg gaaagtggaa aagatttgca cagcatccct gctctcggag gatacccacc
     5341 cctgtgatag caactcatta ctaacaactc ccagtggagg aagcatgttc tctatgggat
     5401 ggccagcttt tttgagcatt acaccaaaca ttaaggaaga aggagcgatg aaagaggatt
     5461 ctggaatgca agatacacca tacaatgaga atatcctggt ggagcagcta tacatgtgtg
     5521 tggagtttct ctggaagtct gagcgatatg aactcattgc tgatgtcaac aagcccatca
     5581 ttgctgtctt tgagaaacaa cgagacttca aaaaattgtc agatctctac tacgacattc
     5641 atcggtcata tctgaaagtg gcagaggtgg tgaattcgga gaagcggctg tttggtcgct
     5701 actatcgtgt ggcattttat gggcagggct tttttgaaga agaagaaggt aaagagtata
     5761 tttataaaga gcctaagctg acaggtctgt ccgagatttc ccaaagatta ctcaagctct
     5821 atgcagataa atttggagca gacaatgtga agataatcca ggattccaac aaggtaaacc
     5881 ccaaggattt ggaccccaaa tatgcctaca tccaggtgac ctatgtgacg ccgttctttg
     5941 aggaaaagga aatcgaagac cggaagacag atttcgaaat gcaccacaac atcaaccgct
     6001 ttgtcttcga gacacccttc acgctgtcgg gcaagaagca cggtggggtg gcggagcagt
     6061 gcaagcggcg gacgatcctg acaacgagtc acctgttccc ctacgtgaag aagagaatac
     6121 aagtaattag ccaatcgagc acagaactga atccaattga agtggcaatt gacgagatgt
     6181 ccaagaaggt ttctgagctt aatcagcttt gcacaatgga agaagtggac atgatcagac
     6241 tgcagctcaa actgcaagga agtgtcagcg tgaaggttaa tgctgggcca atggcctatg
     6301 cacgagcttt tcttgaagaa accaatgcaa agaagtaccc tgacaaccaa gtaaagcttt
     6361 tgaaggagat cttcaggcaa tttgcagatg catgtgggca ggcccttgac gtgaatgagc
     6421 gcctcatcaa agaggaccag ctggagtacc aggaagaact gaggtcccac tacaaggaca
     6481 tgctcagcga actctccaca gtcatgaatg agcagattac gggcagggac gacctgtcaa
     6541 agcgcggagt ggaccaaacc tgcactcgag taattagcaa agcaactccg gccctaccca
     6601 cggtctccat ctcatctagt gctgaagtct gagggctctg cagcatcaga cccacctcta
     6661 agagaacttt ctgaatttgc agctaatctc ggggaagaga aagataggtt taatttattt
     6721 gaagttttca tggtgttaat atttttgttt acctcgctag cttcagaatt ttgccaacct
     6781 ctgaatttgc acattttgta taattttttt ttctttgagc agtgttgatc aagccaggtt
     6841 gaatatttgc catgaaattc cagtgaatgt gtagctcaaa tgcaaaccct aagtttgctg
     6901 tcagttattg tatggtcagt accccagtcc tagtacacat attttaaagg ttaaagtgaa
     6961 tgtttttgta acatttaagc atatttcaga tgtaaataaa agattgtaaa atatacggtt
     7021 tttaccaaat ttaaaagatc ctttttagtt aatactatga cagtactaaa aatatatgaa
     7081 taacatttca gataccatta tattaaaata tttgtgtatg tgtacaaaag cgttgataaa
     7141 tactaatctt taaagtttgt ggagttcctt tatttgtaat atatgtgctc ttaaaagcaa
     7201 tgggatgtga aattatgaaa gtattttatt gttcatagaa ataaaaaaca cagttacttt
     7261 gca
//
