LOCUS       XM_047439960            1874 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens DNA methyltransferase 3 beta (DNMT3B),
            transcript variant X17, mRNA.
ACCESSION   XM_047439960
VERSION     XM_047439960.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000020.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 1% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1874
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
     gene            1..1874
                     /gene="DNMT3B"
                     /gene_synonym="FSHD4; ICF; ICF1; M.HsaIIIB"
                     /note="DNA methyltransferase 3 beta; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 6
                     ESTs, 11 long SRA reads, 1 Protein, and 98% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 2 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:1789"
                     /db_xref="HGNC:HGNC:2979"
                     /db_xref="MIM:602900"
     CDS             265..1737
                     /gene="DNMT3B"
                     /gene_synonym="FSHD4; ICF; ICF1; M.HsaIIIB"
                     /codon_start=1
                     /product="DNA (cytosine-5)-methyltransferase 3B isoform
                     X17"
                     /protein_id="XP_047295916.1"
                     /db_xref="GeneID:1789"
                     /db_xref="HGNC:HGNC:2979"
                     /db_xref="MIM:602900"
                     /translation="MEPSPEPPSLESMKGDTRHLNGEEDAGGREDSILVNGACSDQSS
                     DSPPILEAIRTPEIRGRRSSSRLSKREVSSLLSYTQDLTGDGDGEDGDGSDTPVMPKL
                     FRETRTRSESPASLRRRATASAGTPWPSPPSSYLTIDLTDDTEDTHGTPQSSSTPYAR
                     LAQDSQQGGMESPQVEADSGDGDSSEYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKA
                     TSKRQAMSGMRWVQWFGDGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHAL
                     ERTRLEDAQLTTQPPLTTAPHPSASRQIAITTAKTEGMKIRAENKWLQMLPTTRAAWK
                     MAVCLVAGKTPCPSTLSLRGGSVRHAGIASLSCFTCMMTMAISLTALCAARAESCCFA
                     ATRAAAGVSVWSAWRCWWAQAQRPRPSFRSPGAVTCVSRSAVMASCGAGRTGTCACRP
                     SSPVTRGLNMKPPSCTLPFPQPEGGPFESCHCLMASRQAT"
ORIGIN      
        1 gaagggagag agcaaacaaa ggggtcagga gggaaaataa tgcactggct tcctgagccc
       61 ctgcagaggc tgagcaggga gagggggcca gggccagagg ggacagaggc tggcggcaga
      121 cgggccggga caggcaggtc ctaaatggca ttgtttgaag gggccggcta attgcacaga
      181 gcagtctgag cctgagaccc cagccctggc ctccccactc tgtcctgggt gctggcgtct
      241 gagccttcgg gacagcctgt ccacatggaa ccaagtcctg agcctccaag cttggaaagc
      301 atgaagggag acaccaggca tctcaatgga gaggaggacg ccggcgggag ggaagactcg
      361 atcctcgtca acggggcctg cagcgaccag tcctccgact cgcccccaat cctggaggct
      421 atccgcaccc cggagatcag aggccgaaga tcaagctcgc gactctccaa gagggaggtg
      481 tccagtctgc taagctacac acaggacttg acaggcgatg gcgacgggga agatggggat
      541 ggctctgaca ccccagtcat gccaaagctc ttccgggaaa ccaggactcg ttcagaaagc
      601 ccagcttccc tgagacggcg ggcaacagca tcggcaggaa cgccatggcc gtcccctccc
      661 agctcttacc ttaccatcga cctcacagac gacacagagg acacacatgg gacgccccag
      721 agcagcagta ccccctacgc ccgcctagcc caggacagcc agcagggggg catggagtcc
      781 ccgcaggtgg aggcagacag tggagatgga gacagttcag agtatcagga tgggaaggag
      841 tttggaatag gggacctcgt gtggggaaag atcaagggct tctcctggtg gcccgccatg
      901 gtggtgtctt ggaaggccac ctccaagcga caggctatgt ctggcatgcg gtgggtccag
      961 tggtttggcg atggcaagtt ctccgaggtc tctgcagaca aactggtggc actggggctg
     1021 ttcagccagc actttaattt ggccaccttc aataagctcg tctcctatcg aaaagccatg
     1081 taccatgctc tggagagaac aagactcgaa gacgcacagc tgacgactca gccacctctg
     1141 actactgccc cgcacccaag cgcctcaaga caaattgcta taacaacggc aaagaccgag
     1201 gggatgaaga tcagagccga gaacaaatgg cttcagatgt tgccaacaac aagagcagcc
     1261 tggaagatgg ctgtttgtct tgtggcagga aaaaccccgt gtccttccac cctctctttg
     1321 agggggggct ctgtcagaca tgccgggatc gcttccttga gctgttttac atgtatgatg
     1381 acgatggcta tcagtcttac tgcactgtgt gctgcgaggg ccgagagctg ctgctttgca
     1441 gcaacacgag ctgctgccgg tgtttctgtg tggagtgcct ggaggtgctg gtgggcacag
     1501 gcacagcggc cgaggccaag cttcaggagc cctggagctg ttacatgtgt ctcccgcagc
     1561 gctgtcatgg cgtcctgcgg cgccggaagg actggaacgt gcgcctgcag gccttcttca
     1621 ccagtgacac ggggcttgaa tatgaagccc ccaagctgta ccctgccatt cccgcagccc
     1681 gaaggcggcc cattcgagtc ctgtcattgt ttgatggcat cgcgacaggc tacctagtcc
     1741 tcaaagagtt gggcataaag gtaggaaagt acgtcgcttc tgaagtgtgt gaggagtcca
     1801 ttgctgttgg aaccgtgaag cacgagggga atatcaaata cgtgaacgac gtgaggaaca
     1861 tcacaaagaa aaat
//
