LOCUS       XM_017029332            4217 bp    mRNA    linear   PRI 26-AUG-2024
DEFINITION  PREDICTED: Homo sapiens deoxyribonuclease 1 like 1 (DNASE1L1),
            transcript variant X1, mRNA.
ACCESSION   XM_017029332
VERSION     XM_017029332.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000023.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017029332.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4217
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
     gene            1..4217
                     /gene="DNASE1L1"
                     /gene_synonym="DNAS1L1; DNASEX; DNL1L; G4.8; XIB"
                     /note="deoxyribonuclease 1 like 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 5
                     mRNAs, 25 ESTs, 569 long SRA reads, 5 Proteins, and 80%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 15 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:1774"
                     /db_xref="HGNC:HGNC:2957"
                     /db_xref="MIM:300081"
     CDS             1838..2746
                     /gene="DNASE1L1"
                     /gene_synonym="DNAS1L1; DNASEX; DNL1L; G4.8; XIB"
                     /codon_start=1
                     /product="deoxyribonuclease-1-like 1 isoform X1"
                     /protein_id="XP_016884821.1"
                     /db_xref="GeneID:1774"
                     /db_xref="HGNC:HGNC:2957"
                     /db_xref="MIM:300081"
                     /translation="MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLV
                     RILARCDIMVLQEVVDSSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYF
                     YRSHKTQVLSSYVYNDEDDVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNA
                     LYDVFLEVSQHWQSKDVILLGDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTV
                     RASTHCTYDRVVLHGERCRSLLHTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQ
                     AHSVQPLSLTVLLLLSLLSPQLCPAA"
ORIGIN      
        1 aggtggttca tgtactctgg cggggaagga gaagtcaggc gctccgggct cgcccgctag
       61 gtcggggccg cggcgtcccc caccctaagt cccacctccg gccgggcatg ggtacccggg
      121 cgggcctgcc tcggcctggg cccactcact ggtccagaag cagctgtagg tgcccaccaa
      181 gcccatgacg acgctgctgg ccagggtcca ggagtctcgc tctgtcgcca gactggagtg
      241 cagtggcaca atctcggctc actgcaacct ccgcctcccg ggttcaagct attctcctgc
      301 ctcagcctcc tgagtagctg ggactacagg cgcaggtcgc cacgcccggc taattttttt
      361 ttttttttgt attttagtag agatggggtt tcaccatgtt gcccaggttg gtctcgaact
      421 cctgagctca ggcagtccac ccacctcagc ctcccaaagt gctaggatta caggcatggg
      481 ccaccgcacc cggcagtttt ttatttttat ttttatttat ttttattttt gagacagagt
      541 cttgctctgt tgcccaggct ggagtgcagt gacgagatct cagctcattg caacctctgc
      601 ctcccaggtt caagcgattc ttctgtctca gcctcctgag tagctgggat tacaggcgca
      661 agccaccaca cctggctaat ttttgtattt ttagtagagg ctgggtttct tcatgttggt
      721 caagctggtc tcgaactccc ggcctcaggt gatctgtctg cctctcctcc caaagtgtga
      781 gtcatcctac ctggcctgtt ttttattttt aaaccataat ttattgattt ttttttttga
      841 gatggagtct cgcactgtcg cccgggctgg agtgcgagtg cagtggtgtg atctcggctc
      901 actgcaagct ccgccttcca ggctcaagca attctcctgc ctcagcctcc tgagtagctg
      961 ggattacagg cgcccaccac cacgccgggc taattttttg tatttttagt agaaacgggt
     1021 ttcattatgt tggccaggct ggtcttgaac gcctgacctc gtatccaccc gcctcagcct
     1081 cccaaagtgc tgggattaca ggcatgagcc accacgccca gcccataatt tattgatttt
     1141 ttaaaatttg tccagccttc tattaccacg tcgaatccat tagctacagc catcccatga
     1201 gaagctgagt ggattcagcc ccacctcctg ctcacagacc ctgtccgagc acctcatttg
     1261 tcccaacagc attactgcag gacccccagg acgttggact gccagctccc tgggtctcct
     1321 cctctctggg gcagatcctc agtcctccct tgacttcacg actgtggcca gatcatgtgt
     1381 ggactgtccc tctctttggg tctccagagc gcttgcatca aacaccccta actcagaagt
     1441 gtgcagccac actgggactc agaacccaac aacagggaca gaagactcac gcccttgggg
     1501 tgcccggtct cgtggcatca ggcatgactt ccagctcctg cgccttcccc agcaactgct
     1561 gactggggac ccagaccggg agctgagcga cgggcctggc gagcgaagct cggggtctca
     1621 ctcaggcacc agcccctcct tgccccaggc ttgagtgact cacagcccta ttcaggcagg
     1681 agctgctctt ctggggtatc gcgatccact taaggatgag gcagacttgg tgacaagctg
     1741 gtctgagcag cgcttccaga gccagaactg agcccagtga gagcgcaccc tggggcagcc
     1801 tggattcctg gggtgtcccc ggcagccaca cacagccatg cactacccaa ctgcactcct
     1861 cttcctcatc ctggccaatg gggcccaggc ctttcgcatc tgcgccttca atgcccagcg
     1921 gctgacactg gccaaggtgg ccagggagca ggtgatggac accttagttc ggatactggc
     1981 tcgctgtgac atcatggtgc tgcaggaggt ggtggactct tccggcagcg ccatcccgct
     2041 cctgcttcga gaactcaatc gatttgatgg ctctgggccc tacagcaccc tgagcagccc
     2101 ccagctgggg cgcagcacct acatggagac gtatgtgtac ttctatcggt cacacaaaac
     2161 acaggtcctg agttcctacg tgtacaacga tgaggatgac gtctttgccc gggagccatt
     2221 tgtggcccag ttctctttgc ccagcaatgt ccttcccagc ctggtgttgg tcccgctgca
     2281 caccactcct aaggccgtag agaaggagct gaacgccctc tacgatgtgt ttctggaggt
     2341 ctcccagcac tggcagagca aggacgtgat cctgcttggg gacttcaatg ctgactgcgc
     2401 ttcactgacc aaaaagcgcc tggacaagct ggagctgcgg actgagccag gcttccactg
     2461 ggtgattgcc gatggggagg acaccacagt gcgggccagc acccactgca cctatgaccg
     2521 cgtcgtgctg cacggggagc gctgccggag tctgctgcac actgcggctg cctttgactt
     2581 ccccacgagc ttccagctca ccgaggagga ggccctcaac atcagtgacc actaccccgt
     2641 ggaggtggag ctgaagctga gccaggcgca cagcgtccag cctctcagcc tcactgttct
     2701 gttgctgcta tcactcctgt cccctcagct gtgccctgct gcctgagcgt ccccctaccc
     2761 ccccagggcc tgctgccttt tgggacttaa accccagcct cccccgtcca tccagccctg
     2821 gggctggggg gcttcaacta tagttgccct gtgactgtag tccacccctg cctgccttgt
     2881 ttgatttggc tcttgttctt tggttgggct tgtgcctaga ttaggagagg aagccagggg
     2941 ccctgcactc atgccacctg ccaggtagtg tagtatcagg agtggagaca aagtgggctc
     3001 tgggttgggg taggggaagg gagggttcag aaagaggaat gaagatgttg tatgacaaga
     3061 aggaaagtta ctgagaacaa aaacccagat tggtgagata ggacacttgt gcagcagata
     3121 tgccaatggg ccatgtttat tgtggattgg taagaatcac caggaaacca ttaagcccca
     3181 atagctacaa ggagggtggt taatctgcta tatcaaactc cttccctgaa accagcaaac
     3241 accgggaaac attttggctc attataatcc ggtgaacaat gcagtcaggc ctgttataac
     3301 cgctgagcag ccacactcgc acctcctggg tgctgtagtc tgtgttggta caggcttctg
     3361 catgcctggt aaagtccagc caaggctggt caaggcaaca tctccacaca gaaaatctgc
     3421 accagttatg taagctaaaa agctgtgtga acccaggtgt cccggaaagg ggctgcagga
     3481 cacagcaaaa tgccagcagc atgccggacc cctcccttcc atcctcctct ccaaagaaga
     3541 gaggtcagga aaaacactgg ctgggacgct agaagggtca tgtgttaact ataatcacat
     3601 ttatggtttg gaaccatcac cccaaggtaa aaaaaaaata aaaggtattc ccaggtatgt
     3661 ttggcaaaat aaaataaagg taattaaaaa cctaagaaat ggctgtaaac tgagattaca
     3721 aaaaaccaga ggccttttgg gagccacagg ctgggggctg gggccaacat accccagctc
     3781 tgggaccaaa agcctttgga gtcctgtccc tggatacaga tgctcaggcc acccacctag
     3841 cactcctctc atttttgctg ctcccccaaa agccagcgct gttctacaat agttcaggtc
     3901 agacatctaa gatccccagg ccaaaccatg ccacacacgt gtctgttccg aggtcttgtt
     3961 acaaatgacc aaaggttagc ctagaccttt ggtcaggtgg tgaaggccct gggaatgcag
     4021 gttctagaag gggtgggggc atggggccca ggaggttgct agagatagga aatggggcaa
     4081 atcgcaggtg acctcagcag tacctggatg attcccacca aggaggaatg gccaaaccag
     4141 atgggtgaga acaagcccaa tgtgatgcac acctaccctt gctaaataaa cgctgctggt
     4201 cagcctctag cccacaa
//
