LOCUS       NM_015190               2295 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens DnaJ heat shock protein family (Hsp40) member C9
            (DNAJC9), mRNA.
ACCESSION   NM_015190
VERSION     NM_015190.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2295)
  AUTHORS   Hammond,C.M., Bao,H., Hendriks,I.A., Carraro,M., Garcia-Nieto,A.,
            Liu,Y., Reveron-Gomez,N., Spanos,C., Chen,L., Rappsilber,J.,
            Nielsen,M.L., Patel,D.J., Huang,H. and Groth,A.
  TITLE     DNAJC9 integrates heat shock molecular chaperones into the histone
            chaperone network
  JOURNAL   Mol Cell 81 (12), 2533-2548 (2021)
   PUBMED   33857403
  REMARK    GeneRIF: DNAJC9 integrates heat shock molecular chaperones into the
            histone chaperone network.
REFERENCE   2  (bases 1 to 2295)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 2295)
  AUTHORS   Liu,X., Salokas,K., Tamene,F., Jiu,Y., Weldatsadik,R.G., Ohman,T.
            and Varjosalo,M.
  TITLE     An AP-MS- and BioID-compatible MAC-tag enables comprehensive
            mapping of protein interactions and subcellular localizations
  JOURNAL   Nat Commun 9 (1), 1188 (2018)
   PUBMED   29568061
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2295)
  AUTHORS   Lambert,J.P., Tucholska,M., Go,C., Knight,J.D. and Gingras,A.C.
  TITLE     Proximity biotinylation and affinity purification are complementary
            approaches for the interactome mapping of chromatin-associated
            protein complexes
  JOURNAL   J Proteomics 118, 81-94 (2015)
   PUBMED   25281560
REFERENCE   5  (bases 1 to 2295)
  AUTHORS   Liu,C.M., Fann,C.S., Chen,C.Y., Liu,Y.L., Oyang,Y.J., Yang,W.C.,
            Chang,C.C., Wen,C.C., Chen,W.J., Hwang,T.J., Hsieh,M.H., Liu,C.C.,
            Faraone,S.V., Tsuang,M.T. and Hwu,H.G.
  TITLE     ANXA7, PPP3CB, DNAJC9, and ZMYND17 genes at chromosome 10q22
            associated with the subgroup of schizophrenia with deficits in
            attention and executive function
  JOURNAL   Biol Psychiatry 70 (1), 51-58 (2011)
   PUBMED   21531385
  REMARK    GeneRIF: ANXA7, PPP3CB, DNAJC9, and ZMYND17 genes are potential
            candidate genes for schizophrenia, especially in patients with
            deficits in sustained attention and executive function.
REFERENCE   6  (bases 1 to 2295)
  AUTHORS   Foltz,D.R., Jansen,L.E., Bailey,A.O., Yates,J.R. 3rd, Bassett,E.A.,
            Wood,S., Black,B.E. and Cleveland,D.W.
  TITLE     Centromere-specific assembly of CENP-a nucleosomes is mediated by
            HJURP
  JOURNAL   Cell 137 (3), 472-484 (2009)
   PUBMED   19410544
REFERENCE   7  (bases 1 to 2295)
  AUTHORS   Han,C., Chen,T., Li,N., Yang,M., Wan,T. and Cao,X.
  TITLE     HDJC9, a novel human type C DnaJ/HSP40 member interacts with and
            cochaperones HSP70 through the J domain
  JOURNAL   Biochem Biophys Res Commun 353 (2), 280-285 (2007)
   PUBMED   17182002
REFERENCE   8  (bases 1 to 2295)
  AUTHORS   Takamura,Y., Yagi,H., Hase,K., Yoneda,T., Maeda,M., Akagi,Y. and
            Sato,M.
  TITLE     JDD1, a novel member of the DnaJ family, is expressed in the
            germinal zone of the rat brain
  JOURNAL   Biochem Biophys Res Commun 285 (2), 387-392 (2001)
   PUBMED   11444854
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX646217.1, BC136507.1, BQ954888.1, DA819115.1 and BQ002383.1.
            
            On Nov 22, 2018 this sequence version replaced NM_015190.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11853560.3651.1,
                                           ERR4643830.1063615.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000372950.6/ ENSP00000362041.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                BX646217.1         77-86
            11-911              BC136507.1         14-914
            912-1407            BQ954888.1         273-768
            1408-1618           DA819115.1         256-466
            1619-2295           BQ002383.1         15-691              c
FEATURES             Location/Qualifiers
     source          1..2295
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q22.2"
     gene            1..2295
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
                     /note="DnaJ heat shock protein family (Hsp40) member C9"
                     /db_xref="GeneID:23234"
                     /db_xref="HGNC:HGNC:19123"
                     /db_xref="MIM:611206"
     exon            1..246
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..849
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
                     /note="DnaJ protein SB73; DnaJ (Hsp40) homolog, subfamily
                     C, member 9"
                     /codon_start=1
                     /product="dnaJ homolog subfamily C member 9"
                     /protein_id="NP_056005.1"
                     /db_xref="CCDS:CCDS7322.1"
                     /db_xref="GeneID:23234"
                     /db_xref="HGNC:HGNC:19123"
                     /db_xref="MIM:611206"
                     /translation="MGLLDLCEEVFGTADLYRVLGVRREASDGEVRRGYHKVSLQVHP
                     DRVGEGDKEDATRRFQILGKVYSVLSDREQRAVYDEQGTVDEDSPVLTQDRDWEAYWR
                     LLFKKISLEDIQAFEKTYKGSEEELADIKQAYLDFKGDMDQIMESVLCVQYTEEPRIR
                     NIIQQAIDAGEVPSYNAFVKESKQKMNARKRRAQEEAKEAEMSRKELGLDEGVDSLKA
                     AIQSRQKDRQKEMDNFLAQMEAKYCKSSKGGGKKSALKKEKK"
     exon            247..387
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
                     /inference="alignment:Splign:2.1.0"
     exon            388..642
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
                     /inference="alignment:Splign:2.1.0"
     exon            643..729
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
                     /inference="alignment:Splign:2.1.0"
     exon            730..2295
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1398..1403
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
                     /note="hexamer: AATAAA"
     polyA_site      1418
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
                     /note="major polyA site"
     regulatory      2093..2098
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
                     /note="hexamer: ATTAAA"
     polyA_site      2114
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
     regulatory      2166..2171
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
                     /note="hexamer: AATAAA"
     polyA_site      2183
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
     regulatory      2272..2277
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
                     /note="hexamer: AATAAA"
     polyA_site      2295
                     /gene="DNAJC9"
                     /gene_synonym="HDJC9; JDD1; SB73"
ORIGIN      
        1 agtcctgggt tgtacccggc gcagctggga gcggctgctt cctccggggt cgtatctccg
       61 cccggcatgg ggctgctgga cctttgcgag gaagtgttcg gcaccgccga cctttaccgg
      121 gtgctgggcg tgcgacgcga ggcctccgac ggcgaggtcc gacgaggcta ccacaaggtg
      181 tccctgcagg tacacccgga ccgggtgggt gagggcgaca aggaggacgc cacccgccgc
      241 ttccagatcc tgggaaaagt ctattccgtt ctcagtgaca gagaacagag agcagtgtac
      301 gatgagcagg gaacagtgga cgaggactct cctgtgctca cccaagaccg agactgggag
      361 gcgtattggc ggctactctt taaaaagata tctttagagg acattcaagc ttttgaaaag
      421 acatacaaag gttcggaaga agagctggct gatattaagc aggcctatct ggacttcaag
      481 ggtgacatgg atcagatcat ggagtctgtg ctttgcgtgc agtacacaga ggaacccagg
      541 ataaggaata tcattcagca agctattgac gccggagagg tcccatccta taatgccttt
      601 gtcaaagaat cgaaacaaaa gatgaatgca aggaaaagga gggctcagga agaggccaaa
      661 gaagcagaaa tgagcagaaa ggagttgggg cttgatgaag gcgtggatag cctgaaggca
      721 gccattcaga gcagacaaaa ggatcggcaa aaggaaatgg acaattttct ggctcagatg
      781 gaagcaaagt actgcaaatc ttccaaagga ggagggaaaa aatctgctct caagaaagaa
      841 aagaaataat ggaatttttc tcttcaaagg tccttaggtg taaattgatg ccatcgtagg
      901 caaggtgcag gcaggatttg aaggcaaaag tcaattcagc tcttgagaaa aggtgtcttt
      961 ccagcctgaa tttttcagat tgactagacc aagcagaatc tctcaacctg atcttagtat
     1021 ttcctagaaa gcacttgaca ttgtgtgagg tctcacctga aggaacttgg tggtgacatt
     1081 tgggagggtg gagggaggca gtgtccttcc tgacagcact tgcctccatg gatcttctgt
     1141 acacagaact cttatctagg atgtggttct gttcatgctg ctttctgcga tgtgcgtgtc
     1201 tgttagaata ggctctctac ccagctagaa caccttccag acacttgctg gacagctatc
     1261 ttccacatac ttcccagttt acatttggtc ttaatgatct tgaatagatc ctctcttcat
     1321 tttactcagc caggttttgt actgatgtac aggtgttaaa ttacttcaag catttttgta
     1381 agaggtgtat ataattcaat aaaaaaggta aaacatgatg attaagttct gggggctttg
     1441 taaatgatcc cactaaaatg tgacctagga aaaatatgaa tggtgtttag gatgagagaa
     1501 aaggggaaaa caatagccct ggtcagcttt ataatagaga gcctggtttc cctagcatga
     1561 agagatgtat gttgtagtcc tgccactgat tactgaagtc ctgccattaa ttgctgaatg
     1621 tcttcagttg ggccactgag cttgtctgaa tctgttccct tttataaaag agttactaca
     1681 tcaaaacaaa gagtgaaatc caaatttgtc aaactgtatg tattaaacat gtccagtttt
     1741 ttggttaaaa aaaaattgca ctggctttga gggaaaacac acagggtgag ggaattgggc
     1801 taaatgactt cttacaggcc cctttctgat tctttaactt tgaaaggcaa gccatattga
     1861 tccagttgtt atagtgaact catggtaatg gtttgtgaga acaatagaga ttttcatttc
     1921 tatgtagatg agttggtatg agaatatatg gaatttttaa gggactgttt aaatctttga
     1981 tttgtagact attaaatata ccgtatgcat aaagtaagcc tttagctcta aggtaaagac
     2041 gacacgtttt cggtttgtga ctacaaatag gttaaaaata gattttaatt ttattaaaaa
     2101 tataatttaa tgcaggttgt ttgaagcatc tgtcttcata tgatggcatt agaacacctt
     2161 ggtataataa aaagttaccg taatttatga ttatttgaat ttatccattc tgaaaattaa
     2221 taagatctaa aactggcatg acaatcaaga tttgtattta gtgaaattta aaataaatgt
     2281 aagccatagt taaaa
//
