LOCUS       NM_173650               2065 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens DnaJ heat shock protein family (Hsp40) member C5 gamma
            (DNAJC5G), transcript variant 1, mRNA.
ACCESSION   NM_173650 XM_005264270
VERSION     NM_173650.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2065)
  AUTHORS   Gerhard,D.S., Wagner,L., Feingold,E.A., Shenmen,C.M., Grouse,L.H.,
            Schuler,G., Klein,S.L., Old,S., Rasooly,R., Good,P., Guyer,M.,
            Peck,A.M., Derge,J.G., Lipman,D., Collins,F.S., Jang,W., Sherry,S.,
            Feolo,M., Misquitta,L., Lee,E., Rotmistrovsky,K., Greenhut,S.F.,
            Schaefer,C.F., Buetow,K., Bonner,T.I., Haussler,D., Kent,J.,
            Kiekhaus,M., Furey,T., Brent,M., Prange,C., Schreiber,K.,
            Shapiro,N., Bhat,N.K., Hopkins,R.F., Hsie,F., Driscoll,T.,
            Soares,M.B., Casavant,T.L., Scheetz,T.E., Brown-stein,M.J.,
            Usdin,T.B., Toshiyuki,S., Carninci,P., Piao,Y., Dudekula,D.B.,
            Ko,M.S., Kawakami,K., Suzuki,Y., Sugano,S., Gruber,C.E.,
            Smith,M.R., Simmons,B., Moore,T., Waterman,R., Johnson,S.L.,
            Ruan,Y., Wei,C.L., Mathavan,S., Gunaratne,P.H., Wu,J., Garcia,A.M.,
            Hulyk,S.W., Fuh,E., Yuan,Y., Sneed,A., Kowis,C., Hodgson,A.,
            Muzny,D.M., McPherson,J., Gibbs,R.A., Fahey,J., Helton,E.,
            Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M.,
            Madari,A., Young,A.C., Wetherby,K.D., Granite,S.J., Kwong,P.N.,
            Brinkley,C.P., Pearson,R.L., Bouffard,G.G., Blakesly,R.W.,
            Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J.,
            Myers,R.M., Butterfield,Y.S., Griffith,M., Griffith,O.L.,
            Krzywinski,M.I., Liao,N., Morin,R., Palmquist,D., Petrescu,A.S.,
            Skalska,U., Smailus,D.E., Stott,J.M., Schnerch,A., Schein,J.E.,
            Jones,S.J., Holt,R.A., Baross,A., Marra,M.A., Clifton,S.,
            Makowski,K.A., Bosak,S. and Malek,J.
  CONSRTM   MGC Project Team
  TITLE     The status, quality, and expansion of the NIH full-length cDNA
            project: the Mammalian Gene Collection (MGC)
  JOURNAL   Genome Res 14 (10B), 2121-2127 (2004)
   PUBMED   15489334
  REMARK    Erratum:[Genome Res. 2006 Jun;16(6):804. Morrin, Ryan [corrected to
            Morin, Ryan]]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK097736.1, AF368277.1, AI183575.1, BC035194.2 and AC013413.6.
            
            On May 17, 2019 this sequence version replaced NM_173650.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK097736.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000296097.8/ ENSP00000296097.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-822               AK097736.1         13-834
            823-823             AF368277.1         249-249
            824-1676            AK097736.1         836-1688
            1677-1957           AI183575.1         42-322              c
            1958-1996           BC035194.2         1867-1905
            1997-2065           AC013413.6         64424-64492
FEATURES             Location/Qualifiers
     source          1..2065
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p23.3"
     gene            1..2065
                     /gene="DNAJC5G"
                     /gene_synonym="CSP-gamma"
                     /note="DnaJ heat shock protein family (Hsp40) member C5
                     gamma"
                     /db_xref="GeneID:285126"
                     /db_xref="HGNC:HGNC:24844"
                     /db_xref="MIM:613946"
     exon            1..121
                     /gene="DNAJC5G"
                     /gene_synonym="CSP-gamma"
                     /inference="alignment:Splign:2.1.0"
     exon            122..403
                     /gene="DNAJC5G"
                     /gene_synonym="CSP-gamma"
                     /inference="alignment:Splign:2.1.0"
     exon            404..519
                     /gene="DNAJC5G"
                     /gene_synonym="CSP-gamma"
                     /inference="alignment:Splign:2.1.0"
     CDS             407..976
                     /gene="DNAJC5G"
                     /gene_synonym="CSP-gamma"
                     /note="isoform 1 is encoded by transcript variant 1;
                     gamma-CSP; dnaJ homolog subfamily C member 5G;
                     gamma-cysteine string protein; cysteine string
                     protein-gamma; DnaJ (Hsp40) homolog, subfamily C, member 5
                     gamma"
                     /codon_start=1
                     /product="dnaJ homolog subfamily C member 5G isoform 1"
                     /protein_id="NP_775921.1"
                     /db_xref="CCDS:CCDS1744.1"
                     /db_xref="GeneID:285126"
                     /db_xref="HGNC:HGNC:24844"
                     /db_xref="MIM:613946"
                     /translation="MSTVKEAAHRLSKSEMSLYAVLDLKKGASPEDFKKSYSHSALLP
                     HPPFEYHLGRKLALRYHPDKNPGNAQAAEIFKEINAAHAILSDSKKRKIYDQHGSLGI
                     YLYDHFGEEGVRYYFILNSCWFKTLVILCTLLTCCCFCCCCCFCCGALKPPPEQDSGR
                     KYQQNVQSQPPRSGAKCDFRSEENSEDDF"
     exon            520..781
                     /gene="DNAJC5G"
                     /gene_synonym="CSP-gamma"
                     /inference="alignment:Splign:2.1.0"
     exon            782..926
                     /gene="DNAJC5G"
                     /gene_synonym="CSP-gamma"
                     /inference="alignment:Splign:2.1.0"
     exon            927..994
                     /gene="DNAJC5G"
                     /gene_synonym="CSP-gamma"
                     /inference="alignment:Splign:2.1.0"
     exon            995..2065
                     /gene="DNAJC5G"
                     /gene_synonym="CSP-gamma"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1976..1981
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAJC5G"
                     /gene_synonym="CSP-gamma"
                     /note="hexamer: AATAAA"
     polyA_site      1996
                     /gene="DNAJC5G"
                     /gene_synonym="CSP-gamma"
                     /note="major polyA site"
ORIGIN      
        1 gcccagaccc tcagcgtcga cgctgcgcac aagcgcagtc aactgctgga cccggccggt
       61 gtgaagtttc acacccaaaa ggatgaaggg cacccacctg gcttaagaga acgactccca
      121 gaaaattagc cgggcgtggt ggcgtgcacc tgtaatctca gctactcggg aggctgaggc
      181 aggaaaatcg cttgcaccca ggaggtggag gttgcagtga gccgagatcg cgccattaca
      241 cttcagcctg ggcaacaaga gcaaaaaact ccgtcaaaaa aaaaaaaaag aagaagaagt
      301 tgtggagctg tctgattcct gatcctgtcc gttcaggctg gggccgccct ggtctttcaa
      361 acccagcagt gagcttggac agacccagag gtgtttactc cagatcatgt ctactgtgaa
      421 ggaagcagca caccggctgt ccaaaagtga gatgagcctc tatgcagtgc tggatcttaa
      481 gaagggcgcc tcacctgaag acttcaaaaa atcctacagc cattccgcat tgcttcccca
      541 ccctcctttt gagtatcacc tgggtaggaa actggccttg cggtatcatc ccgacaagaa
      601 tccagggaat gctcaagcag cagaaatatt caaagagatc aacgcagctc atgccatact
      661 gagcgactct aagaagcgga aaatttacga ccagcatggc tcattgggaa tatatctgta
      721 tgatcacttt ggtgaagaag gcgtcagata ctattttatt ctgaatagtt gttggttcaa
      781 gacacttgtc atcctgtgta ctctgctcac ttgttgctgt ttctgttgtt gctgctgttt
      841 ttgctgtgga gcacttaaac caccacctga gcaggatagt gggagaaaat atcagcagaa
      901 tgtccagagt cagcctccaa ggtcaggagc caaatgtgat tttagaagcg aggaaaatag
      961 cgaagatgat ttttaagaga tgaagaagga tgaggtgctg acccagtgag ggtgccttct
     1021 gctgcccagt cccctggaca cattgaagag aggagcaagt agccctgtcc tgacattgac
     1081 cctgatttga cccctcttct tataaggatc tcaagaatct cttcagaagc actgatgacg
     1141 ttgatcccag taaggacatc acctctaccc ttggtaccac aactctgtat ggggttgccc
     1201 agctactctt cctttcagtt gcagtcccaa ttttactccg tcagaaagca gccctcccct
     1261 ccctcccctt atgaggtctc aggcagtggt ggcagatttt tcctgaagag tctttttcct
     1321 gtgtctgcct tgttattgga accaatgcca gctggtagga tccctgagcc ccttgcgata
     1381 tcaccaccaa gagcctgata actgagcagg gtggatcctg tccctggagc tgctgcaccc
     1441 attaattctc ccttgttgca actctgtgta ccaagaaccc ctagcatcag cctcattcct
     1501 aagccaataa cgcctgtatg gagttggttt catcttctgg tgcccacggc cattggcatt
     1561 gccagcctca ttccatgcca ctatgagtca actcaggaaa actgcgagtg catttgaggc
     1621 ttaggggtag tcattccatc tttagattat ccttggactt cagctaccag cacagcatgc
     1681 attagccttg gtcctgtagg ttaactgaag ttcaaacatc agtgccagct tgcctccatc
     1741 cttttcacat attatgcagg ccaattgaca tataatttgt tcttaaaaat aggggcatga
     1801 aatatgtgat ctggaaaaga ttgtactttc tggactcttt tcccactctt gcctctttgt
     1861 gctgctgttt cgtatcctcc tcacaccgtg tatttcccac ccactcaggg tcacagccta
     1921 ctaattcctc aaacttctct ccctggacta ggagaaaggc taaagaatgt cagtaaataa
     1981 aagagctttc atccaatccc aaggcatata ttatgcccaa aaaagacaaa ttgtgtctgg
     2041 ggtagagaaa aaaggcctaa agaaa
//
