LOCUS       NM_016544               4847 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens DnaJ heat shock protein family (Hsp40) member C27
            (DNAJC27), transcript variant 1, mRNA.
ACCESSION   NM_016544
VERSION     NM_016544.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4847)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 4847)
  AUTHORS   He,M., Xu,M., Zhang,B., Liang,J., Chen,P., Lee,J.Y., Johnson,T.A.,
            Li,H., Yang,X., Dai,J., Liang,L., Gui,L., Qi,Q., Huang,J., Li,Y.,
            Adair,L.S., Aung,T., Cai,Q., Cheng,C.Y., Cho,M.C., Cho,Y.S.,
            Chu,M., Cui,B., Gao,Y.T., Go,M.J., Gu,D., Gu,W., Guo,H., Hao,Y.,
            Hong,J., Hu,Z., Hu,Y., Huang,J., Hwang,J.Y., Ikram,M.K., Jin,G.,
            Kang,D.H., Khor,C.C., Kim,B.J., Kim,H.T., Kubo,M., Lee,J., Lee,J.,
            Lee,N.R., Li,R., Li,J., Liu,J., Longe,J., Lu,W., Lu,X., Miao,X.,
            Okada,Y., Ong,R.T., Qiu,G., Seielstad,M., Sim,X., Song,H.,
            Takeuchi,F., Tanaka,T., Taylor,P.R., Wang,L., Wang,W., Wang,Y.,
            Wu,C., Wu,Y., Xiang,Y.B., Yamamoto,K., Yang,H., Liao,M., Yokota,M.,
            Young,T., Zhang,X., Kato,N., Wang,Q.K., Zheng,W., Hu,F.B., Lin,D.,
            Shen,H., Teo,Y.Y., Mo,Z., Wong,T.Y., Lin,X., Mohlke,K.L., Ning,G.,
            Tsunoda,T., Han,B.G., Shu,X.O., Tai,E.S., Wu,T. and Qi,L.
  TITLE     Meta-analysis of genome-wide association studies of adult height in
            East Asians identifies 17 novel loci
  JOURNAL   Hum Mol Genet 24 (6), 1791-1800 (2015)
   PUBMED   25429064
REFERENCE   3  (bases 1 to 4847)
  AUTHORS   Wen,W., Zheng,W., Okada,Y., Takeuchi,F., Tabara,Y., Hwang,J.Y.,
            Dorajoo,R., Li,H., Tsai,F.J., Yang,X., He,J., Wu,Y., He,M.,
            Zhang,Y., Liang,J., Guo,X., Sheu,W.H., Delahanty,R., Guo,X.,
            Kubo,M., Yamamoto,K., Ohkubo,T., Go,M.J., Liu,J.J., Gan,W.,
            Chen,C.C., Gao,Y., Li,S., Lee,N.R., Wu,C., Zhou,X., Song,H.,
            Yao,J., Lee,I.T., Long,J., Tsunoda,T., Akiyama,K., Takashima,N.,
            Cho,Y.S., Ong,R.T., Lu,L., Chen,C.H., Tan,A., Rice,T.K.,
            Adair,L.S., Gui,L., Allison,M., Lee,W.J., Cai,Q., Isomura,M.,
            Umemura,S., Kim,Y.J., Seielstad,M., Hixson,J., Xiang,Y.B.,
            Isono,M., Kim,B.J., Sim,X., Lu,W., Nabika,T., Lee,J., Lim,W.Y.,
            Gao,Y.T., Takayanagi,R., Kang,D.H., Wong,T.Y., Hsiung,C.A.,
            Wu,I.C., Juang,J.M., Shi,J., Choi,B.Y., Aung,T., Hu,F., Kim,M.K.,
            Lim,W.Y., Wang,T.D., Shin,M.H., Lee,J., Ji,B.T., Lee,Y.H.,
            Young,T.L., Shin,D.H., Chun,B.Y., Cho,M.C., Han,B.G., Hwu,C.M.,
            Assimes,T.L., Absher,D., Yan,X., Kim,E., Kuo,J.Z., Kwon,S.,
            Taylor,K.D., Chen,Y.D., Rotter,J.I., Qi,L., Zhu,D., Wu,T.,
            Mohlke,K.L., Gu,D., Mo,Z., Wu,J.Y., Lin,X., Miki,T., Tai,E.S.,
            Lee,J.Y., Kato,N., Shu,X.O. and Tanaka,T.
  TITLE     Meta-analysis of genome-wide association studies in East
            Asian-ancestry populations identifies four new loci for body mass
            index
  JOURNAL   Hum Mol Genet 23 (20), 5492-5504 (2014)
   PUBMED   24861553
REFERENCE   4  (bases 1 to 4847)
  AUTHORS   Chen,T., Yang,M., Yu,Z., Tang,S., Wang,C., Zhu,X., Guo,J., Li,N.,
            Zhang,W., Hou,J., Liu,H., Han,C., Liu,Q., Gu,Y., Qian,C., Wan,T.,
            Cui,L., Zhu,M., Zheng,W. and Cao,X.
  TITLE     Small GTPase RBJ mediates nuclear entrapment of MEK1/MEK2 in tumor
            progression
  JOURNAL   Cancer Cell 25 (5), 682-696 (2014)
   PUBMED   24746703
  REMARK    GeneRIF: these data suggest that RBJ may be an oncogenic
            Ras-related small GTPase mediating nuclear accumulation of active
            MEK1/MEK2 in tumor progression.
            Erratum:[Cancer Cell. 2021 Mar 8;39(3):438-440. doi:
            10.1016/j.ccell.2021.02.010.. PMID: 33689704]
REFERENCE   5  (bases 1 to 4847)
  AUTHORS   Cousminer,D.L., Berry,D.J., Timpson,N.J., Ang,W., Thiering,E.,
            Byrne,E.M., Taal,H.R., Huikari,V., Bradfield,J.P., Kerkhof,M.,
            Groen-Blokhuis,M.M., Kreiner-Moller,E., Marinelli,M., Holst,C.,
            Leinonen,J.T., Perry,J.R., Surakka,I., Pietilainen,O., Kettunen,J.,
            Anttila,V., Kaakinen,M., Sovio,U., Pouta,A., Das,S., Lagou,V.,
            Power,C., Prokopenko,I., Evans,D.M., Kemp,J.P., St Pourcain,B.,
            Ring,S., Palotie,A., Kajantie,E., Osmond,C., Lehtimaki,T.,
            Viikari,J.S., Kahonen,M., Warrington,N.M., Lye,S.J., Palmer,L.J.,
            Tiesler,C.M., Flexeder,C., Montgomery,G.W., Medland,S.E.,
            Hofman,A., Hakonarson,H., Guxens,M., Bartels,M., Salomaa,V.,
            Murabito,J.M., Kaprio,J., Sorensen,T.I., Ballester,F., Bisgaard,H.,
            Boomsma,D.I., Koppelman,G.H., Grant,S.F., Jaddoe,V.W., Martin,N.G.,
            Heinrich,J., Pennell,C.E., Raitakari,O.T., Eriksson,J.G.,
            Smith,G.D., Hypponen,E., Jarvelin,M.R., McCarthy,M.I., Ripatti,S.
            and Widen,E.
  CONSRTM   ReproGen Consortium; Early Growth Genetics (EGG) Consortium
  TITLE     Genome-wide association and longitudinal analyses reveal genetic
            loci linking pubertal height growth, pubertal timing and childhood
            adiposity
  JOURNAL   Hum Mol Genet 22 (13), 2735-2747 (2013)
   PUBMED   23449627
REFERENCE   6  (bases 1 to 4847)
  AUTHORS   Speliotes,E.K., Willer,C.J., Berndt,S.I., Monda,K.L.,
            Thorleifsson,G., Jackson,A.U., Lango Allen,H., Lindgren,C.M.,
            Luan,J., Magi,R., Randall,J.C., Vedantam,S., Winkler,T.W., Qi,L.,
            Workalemahu,T., Heid,I.M., Steinthorsdottir,V., Stringham,H.M.,
            Weedon,M.N., Wheeler,E., Wood,A.R., Ferreira,T., Weyant,R.J.,
            Segre,A.V., Estrada,K., Liang,L., Nemesh,J., Park,J.H.,
            Gustafsson,S., Kilpelainen,T.O., Yang,J., Bouatia-Naji,N., Esko,T.,
            Feitosa,M.F., Kutalik,Z., Mangino,M., Raychaudhuri,S., Scherag,A.,
            Smith,A.V., Welch,R., Zhao,J.H., Aben,K.K., Absher,D.M., Amin,N.,
            Dixon,A.L., Fisher,E., Glazer,N.L., Goddard,M.E., Heard-Costa,N.L.,
            Hoesel,V., Hottenga,J.J., Johansson,A., Johnson,T., Ketkar,S.,
            Lamina,C., Li,S., Moffatt,M.F., Myers,R.H., Narisu,N., Perry,J.R.,
            Peters,M.J., Preuss,M., Ripatti,S., Rivadeneira,F., Sandholt,C.,
            Scott,L.J., Timpson,N.J., Tyrer,J.P., van Wingerden,S.,
            Watanabe,R.M., White,C.C., Wiklund,F., Barlassina,C., Chasman,D.I.,
            Cooper,M.N., Jansson,J.O., Lawrence,R.W., Pellikka,N.,
            Prokopenko,I., Shi,J., Thiering,E., Alavere,H., Alibrandi,M.T.,
            Almgren,P., Arnold,A.M., Aspelund,T., Atwood,L.D., Balkau,B.,
            Balmforth,A.J., Bennett,A.J., Ben-Shlomo,Y., Bergman,R.N.,
            Bergmann,S., Biebermann,H., Blakemore,A.I., Boes,T.,
            Bonnycastle,L.L., Bornstein,S.R., Brown,M.J., Buchanan,T.A.,
            Busonero,F., Campbell,H., Cappuccio,F.P., Cavalcanti-Proenca,C.,
            Chen,Y.D., Chen,C.M., Chines,P.S., Clarke,R., Coin,L., Connell,J.,
            Day,I.N., den Heijer,M., Duan,J., Ebrahim,S., Elliott,P.,
            Elosua,R., Eiriksdottir,G., Erdos,M.R., Eriksson,J.G.,
            Facheris,M.F., Felix,S.B., Fischer-Posovszky,P., Folsom,A.R.,
            Friedrich,N., Freimer,N.B., Fu,M., Gaget,S., Gejman,P.V.,
            Geus,E.J., Gieger,C., Gjesing,A.P., Goel,A., Goyette,P.,
            Grallert,H., Grassler,J., Greenawalt,D.M., Groves,C.J.,
            Gudnason,V., Guiducci,C., Hartikainen,A.L., Hassanali,N.,
            Hall,A.S., Havulinna,A.S., Hayward,C., Heath,A.C., Hengstenberg,C.,
            Hicks,A.A., Hinney,A., Hofman,A., Homuth,G., Hui,J., Igl,W.,
            Iribarren,C., Isomaa,B., Jacobs,K.B., Jarick,I., Jewell,E.,
            John,U., Jorgensen,T., Jousilahti,P., Jula,A., Kaakinen,M.,
            Kajantie,E., Kaplan,L.M., Kathiresan,S., Kettunen,J., Kinnunen,L.,
            Knowles,J.W., Kolcic,I., Konig,I.R., Koskinen,S., Kovacs,P.,
            Kuusisto,J., Kraft,P., Kvaloy,K., Laitinen,J., Lantieri,O.,
            Lanzani,C., Launer,L.J., Lecoeur,C., Lehtimaki,T., Lettre,G.,
            Liu,J., Lokki,M.L., Lorentzon,M., Luben,R.N., Ludwig,B.,
            Manunta,P., Marek,D., Marre,M., Martin,N.G., McArdle,W.L.,
            McCarthy,A., McKnight,B., Meitinger,T., Melander,O., Meyre,D.,
            Midthjell,K., Montgomery,G.W., Morken,M.A., Morris,A.P., Mulic,R.,
            Ngwa,J.S., Nelis,M., Neville,M.J., Nyholt,D.R., O'Donnell,C.J.,
            O'Rahilly,S., Ong,K.K., Oostra,B., Pare,G., Parker,A.N., Perola,M.,
            Pichler,I., Pietilainen,K.H., Platou,C.G., Polasek,O., Pouta,A.,
            Rafelt,S., Raitakari,O., Rayner,N.W., Ridderstrale,M., Rief,W.,
            Ruokonen,A., Robertson,N.R., Rzehak,P., Salomaa,V., Sanders,A.R.,
            Sandhu,M.S., Sanna,S., Saramies,J., Savolainen,M.J., Scherag,S.,
            Schipf,S., Schreiber,S., Schunkert,H., Silander,K., Sinisalo,J.,
            Siscovick,D.S., Smit,J.H., Soranzo,N., Sovio,U., Stephens,J.,
            Surakka,I., Swift,A.J., Tammesoo,M.L., Tardif,J.C.,
            Teder-Laving,M., Teslovich,T.M., Thompson,J.R., Thomson,B.,
            Tonjes,A., Tuomi,T., van Meurs,J.B., van Ommen,G.J., Vatin,V.,
            Viikari,J., Visvikis-Siest,S., Vitart,V., Vogel,C.I., Voight,B.F.,
            Waite,L.L., Wallaschofski,H., Walters,G.B., Widen,E., Wiegand,S.,
            Wild,S.H., Willemsen,G., Witte,D.R., Witteman,J.C., Xu,J.,
            Zhang,Q., Zgaga,L., Ziegler,A., Zitting,P., Beilby,J.P.,
            Farooqi,I.S., Hebebrand,J., Huikuri,H.V., James,A.L., Kahonen,M.,
            Levinson,D.F., Macciardi,F., Nieminen,M.S., Ohlsson,C.,
            Palmer,L.J., Ridker,P.M., Stumvoll,M., Beckmann,J.S., Boeing,H.,
            Boerwinkle,E., Boomsma,D.I., Caulfield,M.J., Chanock,S.J.,
            Collins,F.S., Cupples,L.A., Smith,G.D., Erdmann,J., Froguel,P.,
            Gronberg,H., Gyllensten,U., Hall,P., Hansen,T., Harris,T.B.,
            Hattersley,A.T., Hayes,R.B., Heinrich,J., Hu,F.B., Hveem,K.,
            Illig,T., Jarvelin,M.R., Kaprio,J., Karpe,F., Khaw,K.T.,
            Kiemeney,L.A., Krude,H., Laakso,M., Lawlor,D.A., Metspalu,A.,
            Munroe,P.B., Ouwehand,W.H., Pedersen,O., Penninx,B.W., Peters,A.,
            Pramstaller,P.P., Quertermous,T., Reinehr,T., Rissanen,A.,
            Rudan,I., Samani,N.J., Schwarz,P.E., Shuldiner,A.R., Spector,T.D.,
            Tuomilehto,J., Uda,M., Uitterlinden,A., Valle,T.T., Wabitsch,M.,
            Waeber,G., Wareham,N.J., Watkins,H., Wilson,J.F., Wright,A.F.,
            Zillikens,M.C., Chatterjee,N., McCarroll,S.A., Purcell,S.,
            Schadt,E.E., Visscher,P.M., Assimes,T.L., Borecki,I.B.,
            Deloukas,P., Fox,C.S., Groop,L.C., Haritunians,T., Hunter,D.J.,
            Kaplan,R.C., Mohlke,K.L., O'Connell,J.R., Peltonen,L.,
            Schlessinger,D., Strachan,D.P., van Duijn,C.M., Wichmann,H.E.,
            Frayling,T.M., Thorsteinsdottir,U., Abecasis,G.R., Barroso,I.,
            Boehnke,M., Stefansson,K., North,K.E., McCarthy,M.I.,
            Hirschhorn,J.N., Ingelsson,E. and Loos,R.J.
  CONSRTM   MAGIC; Procardis Consortium
  TITLE     Association analyses of 249,796 individuals reveal 18 new loci
            associated with body mass index
  JOURNAL   Nat Genet 42 (11), 937-948 (2010)
   PUBMED   20935630
REFERENCE   7  (bases 1 to 4847)
  AUTHORS   Lango Allen,H., Estrada,K., Lettre,G., Berndt,S.I., Weedon,M.N.,
            Rivadeneira,F., Willer,C.J., Jackson,A.U., Vedantam,S.,
            Raychaudhuri,S., Ferreira,T., Wood,A.R., Weyant,R.J., Segre,A.V.,
            Speliotes,E.K., Wheeler,E., Soranzo,N., Park,J.H., Yang,J.,
            Gudbjartsson,D., Heard-Costa,N.L., Randall,J.C., Qi,L., Vernon
            Smith,A., Magi,R., Pastinen,T., Liang,L., Heid,I.M., Luan,J.,
            Thorleifsson,G., Winkler,T.W., Goddard,M.E., Sin Lo,K., Palmer,C.,
            Workalemahu,T., Aulchenko,Y.S., Johansson,A., Zillikens,M.C.,
            Feitosa,M.F., Esko,T., Johnson,T., Ketkar,S., Kraft,P., Mangino,M.,
            Prokopenko,I., Absher,D., Albrecht,E., Ernst,F., Glazer,N.L.,
            Hayward,C., Hottenga,J.J., Jacobs,K.B., Knowles,J.W., Kutalik,Z.,
            Monda,K.L., Polasek,O., Preuss,M., Rayner,N.W., Robertson,N.R.,
            Steinthorsdottir,V., Tyrer,J.P., Voight,B.F., Wiklund,F., Xu,J.,
            Zhao,J.H., Nyholt,D.R., Pellikka,N., Perola,M., Perry,J.R.,
            Surakka,I., Tammesoo,M.L., Altmaier,E.L., Amin,N., Aspelund,T.,
            Bhangale,T., Boucher,G., Chasman,D.I., Chen,C., Coin,L.,
            Cooper,M.N., Dixon,A.L., Gibson,Q., Grundberg,E., Hao,K., Juhani
            Junttila,M., Kaplan,L.M., Kettunen,J., Konig,I.R., Kwan,T.,
            Lawrence,R.W., Levinson,D.F., Lorentzon,M., McKnight,B.,
            Morris,A.P., Muller,M., Suh Ngwa,J., Purcell,S., Rafelt,S.,
            Salem,R.M., Salvi,E., Sanna,S., Shi,J., Sovio,U., Thompson,J.R.,
            Turchin,M.C., Vandenput,L., Verlaan,D.J., Vitart,V., White,C.C.,
            Ziegler,A., Almgren,P., Balmforth,A.J., Campbell,H., Citterio,L.,
            De Grandi,A., Dominiczak,A., Duan,J., Elliott,P., Elosua,R.,
            Eriksson,J.G., Freimer,N.B., Geus,E.J., Glorioso,N., Haiqing,S.,
            Hartikainen,A.L., Havulinna,A.S., Hicks,A.A., Hui,J., Igl,W.,
            Illig,T., Jula,A., Kajantie,E., Kilpelainen,T.O., Koiranen,M.,
            Kolcic,I., Koskinen,S., Kovacs,P., Laitinen,J., Liu,J., Lokki,M.L.,
            Marusic,A., Maschio,A., Meitinger,T., Mulas,A., Pare,G.,
            Parker,A.N., Peden,J.F., Petersmann,A., Pichler,I.,
            Pietilainen,K.H., Pouta,A., Ridderstrale,M., Rotter,J.I.,
            Sambrook,J.G., Sanders,A.R., Schmidt,C.O., Sinisalo,J., Smit,J.H.,
            Stringham,H.M., Bragi Walters,G., Widen,E., Wild,S.H.,
            Willemsen,G., Zagato,L., Zgaga,L., Zitting,P., Alavere,H.,
            Farrall,M., McArdle,W.L., Nelis,M., Peters,M.J., Ripatti,S., van
            Meurs,J.B., Aben,K.K., Ardlie,K.G., Beckmann,J.S., Beilby,J.P.,
            Bergman,R.N., Bergmann,S., Collins,F.S., Cusi,D., den Heijer,M.,
            Eiriksdottir,G., Gejman,P.V., Hall,A.S., Hamsten,A., Huikuri,H.V.,
            Iribarren,C., Kahonen,M., Kaprio,J., Kathiresan,S., Kiemeney,L.,
            Kocher,T., Launer,L.J., Lehtimaki,T., Melander,O., Mosley,T.H. Jr.,
            Musk,A.W., Nieminen,M.S., O'Donnell,C.J., Ohlsson,C., Oostra,B.,
            Palmer,L.J., Raitakari,O., Ridker,P.M., Rioux,J.D., Rissanen,A.,
            Rivolta,C., Schunkert,H., Shuldiner,A.R., Siscovick,D.S.,
            Stumvoll,M., Tonjes,A., Tuomilehto,J., van Ommen,G.J., Viikari,J.,
            Heath,A.C., Martin,N.G., Montgomery,G.W., Province,M.A., Kayser,M.,
            Arnold,A.M., Atwood,L.D., Boerwinkle,E., Chanock,S.J., Deloukas,P.,
            Gieger,C., Gronberg,H., Hall,P., Hattersley,A.T., Hengstenberg,C.,
            Hoffman,W., Lathrop,G.M., Salomaa,V., Schreiber,S., Uda,M.,
            Waterworth,D., Wright,A.F., Assimes,T.L., Barroso,I., Hofman,A.,
            Mohlke,K.L., Boomsma,D.I., Caulfield,M.J., Cupples,L.A.,
            Erdmann,J., Fox,C.S., Gudnason,V., Gyllensten,U., Harris,T.B.,
            Hayes,R.B., Jarvelin,M.R., Mooser,V., Munroe,P.B., Ouwehand,W.H.,
            Penninx,B.W., Pramstaller,P.P., Quertermous,T., Rudan,I.,
            Samani,N.J., Spector,T.D., Volzke,H., Watkins,H., Wilson,J.F.,
            Groop,L.C., Haritunians,T., Hu,F.B., Kaplan,R.C., Metspalu,A.,
            North,K.E., Schlessinger,D., Wareham,N.J., Hunter,D.J.,
            O'Connell,J.R., Strachan,D.P., Wichmann,H.E., Borecki,I.B., van
            Duijn,C.M., Schadt,E.E., Thorsteinsdottir,U., Peltonen,L.,
            Uitterlinden,A.G., Visscher,P.M., Chatterjee,N., Loos,R.J.,
            Boehnke,M., McCarthy,M.I., Ingelsson,E., Lindgren,C.M.,
            Abecasis,G.R., Stefansson,K., Frayling,T.M. and Hirschhorn,J.N.
  TITLE     Hundreds of variants clustered in genomic loci and biological
            pathways affect human height
  JOURNAL   Nature 467 (7317), 832-838 (2010)
   PUBMED   20881960
REFERENCE   8  (bases 1 to 4847)
  AUTHORS   Hendrickson,S.L., Lautenberger,J.A., Chinn,L.W., Malasky,M.,
            Sezgin,E., Kingsley,L.A., Goedert,J.J., Kirk,G.D., Gomperts,E.D.,
            Buchbinder,S.P., Troyer,J.L. and O'Brien,S.J.
  TITLE     Genetic variants in nuclear-encoded mitochondrial genes influence
            AIDS progression
  JOURNAL   PLoS One 5 (9), e12862 (2010)
   PUBMED   20877624
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
            Publication Status: Online-Only
REFERENCE   9  (bases 1 to 4847)
  AUTHORS   Gudbjartsson,D.F., Walters,G.B., Thorleifsson,G., Stefansson,H.,
            Halldorsson,B.V., Zusmanovich,P., Sulem,P., Thorlacius,S.,
            Gylfason,A., Steinberg,S., Helgadottir,A., Ingason,A.,
            Steinthorsdottir,V., Olafsdottir,E.J., Olafsdottir,G.H.,
            Jonsson,T., Borch-Johnsen,K., Hansen,T., Andersen,G., Jorgensen,T.,
            Pedersen,O., Aben,K.K., Witjes,J.A., Swinkels,D.W., den Heijer,M.,
            Franke,B., Verbeek,A.L., Becker,D.M., Yanek,L.R., Becker,L.C.,
            Tryggvadottir,L., Rafnar,T., Gulcher,J., Kiemeney,L.A., Kong,A.,
            Thorsteinsdottir,U. and Stefansson,K.
  TITLE     Many sequence variants affecting diversity of adult human height
  JOURNAL   Nat Genet 40 (5), 609-615 (2008)
   PUBMED   18391951
REFERENCE   10 (bases 1 to 4847)
  AUTHORS   Nepomuceno-Silva,J.L., de Melo,L.D., Mendonca,S.M., Paixao,J.C. and
            Lopes,U.G.
  TITLE     RJLs: a new family of Ras-related GTP-binding proteins
  JOURNAL   Gene 327 (2), 221-232 (2004)
   PUBMED   14980719
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC013267.11, BC034049.1 and AC012073.9.
            
            On May 17, 2019 this sequence version replaced NM_016544.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC034049.1, SRR1803611.55273.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000264711.7/ ENSP00000264711.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-84                AC013267.11        20972-21055         c
            85-2391             BC034049.1         85-2391
            2392-4390           AC012073.9         146791-148789       c
            4391-4847           BC034049.1         4391-4847
FEATURES             Location/Qualifiers
     source          1..4847
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p23.3"
     gene            1..4847
                     /gene="DNAJC27"
                     /gene_synonym="RabJS; RBJ"
                     /note="DnaJ heat shock protein family (Hsp40) member C27"
                     /db_xref="GeneID:51277"
                     /db_xref="HGNC:HGNC:30290"
                     /db_xref="MIM:613527"
     exon            1..138
                     /gene="DNAJC27"
                     /gene_synonym="RabJS; RBJ"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..873
                     /gene="DNAJC27"
                     /gene_synonym="RabJS; RBJ"
                     /EC_number="4.6.1.1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     Ras-associated protein Rap1; dnaJ homolog subfamily C
                     member 27; rab and DnaJ domain-containing protein; DnaJ
                     (Hsp40) homolog, subfamily C, member 27"
                     /codon_start=1
                     /product="dnaJ homolog subfamily C member 27 isoform 1"
                     /protein_id="NP_057628.1"
                     /db_xref="CCDS:CCDS1716.1"
                     /db_xref="GeneID:51277"
                     /db_xref="HGNC:HGNC:30290"
                     /db_xref="MIM:613527"
                     /translation="MEANMPKRKEPGRSLRIKVISMGNAEVGKSCIIKRYCEKRFVSK
                     YLATIGIDYGVTKVHVRDREIKVNIFDMAGHPFFYEVRNEFYKDTQGVILVYDVGQKD
                     SFDALDAWLAEMKQELGPHGNMENIIFVVCANKIDCTKHRCVDESEGRLWAESKGFLY
                     FETSAQTGEGINEMFQTFYISIVDLCENGGKRPTTNSSASFTKEQADAIRRIRNSKDS
                     WDMLGVKPGASRDEVNKAYRKLAVLLHPDKCVAPGSEDAFKAVVNARTALLKNIK"
     exon            139..221
                     /gene="DNAJC27"
                     /gene_synonym="RabJS; RBJ"
                     /inference="alignment:Splign:2.1.0"
     exon            222..291
                     /gene="DNAJC27"
                     /gene_synonym="RabJS; RBJ"
                     /inference="alignment:Splign:2.1.0"
     exon            292..456
                     /gene="DNAJC27"
                     /gene_synonym="RabJS; RBJ"
                     /inference="alignment:Splign:2.1.0"
     exon            457..579
                     /gene="DNAJC27"
                     /gene_synonym="RabJS; RBJ"
                     /inference="alignment:Splign:2.1.0"
     exon            580..740
                     /gene="DNAJC27"
                     /gene_synonym="RabJS; RBJ"
                     /inference="alignment:Splign:2.1.0"
     exon            741..4847
                     /gene="DNAJC27"
                     /gene_synonym="RabJS; RBJ"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4829..4834
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAJC27"
                     /gene_synonym="RabJS; RBJ"
                     /note="hexamer: AGTAAA"
     polyA_site      4847
                     /gene="DNAJC27"
                     /gene_synonym="RabJS; RBJ"
                     /note="major polyA site"
ORIGIN      
        1 agcggtgcac aagaagagac cgaggcgggt ggccccgaga gagccagggc catggaggcc
       61 aacatgccga agcggaagga gcccggcagg tctctccgca tcaaagtcat ctccatgggc
      121 aacgccgaag tggggaaaag ctgtattata aagcgatact gtgagaaaag attcgtgtct
      181 aaatacctgg caacaattgg aattgactat ggagtcacaa aggtacacgt cagagacaga
      241 gaaatcaaag ttaacatctt tgatatggct ggacatccct tcttctatga ggttcgaaat
      301 gagttttaca aggacacaca gggtgtgata ctggtctatg atgttgggca gaaagactcc
      361 tttgacgccc ttgatgcgtg gctggcagaa atgaagcaag agcttggacc tcatggaaac
      421 atggaaaata ttatatttgt agtttgtgcc aacaagattg attgtaccaa acatcgctgt
      481 gtagatgaaa gtgaaggacg tctttgggct gaaagcaaag ggttcctgta ctttgaaact
      541 tcagcacaaa ctggagaagg cattaatgag atgttccaga ccttttatat atccatagtt
      601 gatttatgtg aaaatggcgg gaaacgccct accaccaata gcagtgctag tttcaccaaa
      661 gaacaagcag atgccattcg cagaattcga aatagtaaag acagttggga catgctggga
      721 gtcaaacctg gggcctcaag ggatgaagtc aataaagcgt atcggaaact tgctgtgctt
      781 cttcaccctg acaaatgtgt agcacctggc agtgaagatg ccttcaaagc agttgtgaat
      841 gctcggacag ccctcctgaa aaacatcaag tagaaagtac agaaaaaagc cacatgtggg
      901 actcaaatgc aaacagactt tccctagagg tgaaataacc aacgtggagt tttccttccc
      961 agaatctcac tgctcttttc attcatgtgt tgtcatttgt atatcagtaa ttcaggtacc
     1021 catttcatag acattttact gagaaatgac ctgcatttgt atgaagtgaa ctgagcgtca
     1081 caccctgtac ttcatttcat atttctagat aattctgaat ttttttctca ttcgtcagct
     1141 ctgtaattat agtatcactt agacatttca cttggggaaa tccacaaggt tcctggagga
     1201 gggaagagag gacaagagga ccctttcact ttttcttttt tacggaattc atcatcagag
     1261 aagaaaataa caaaaatgga agcaaacaac atcagaaccc ctgtaagttt ggtgtgacct
     1321 tacagacaag ttgctgcttt tacaatgagt tccttaggtg gtattttaac ccatcgatct
     1381 ataatgatga ctcttggcag ccctttggga gtttgtaaaa tgaggtgata cagttctgaa
     1441 ttgagcattc ctttatgata ttcactctgt tcctcttctg cagccaccag tgggagagac
     1501 aagccagtcc taagagaaaa ggtggtggca gccacaaatt ctaggtacac tggctgctgc
     1561 ctatcctgtc cctggatctg aggcctttcc cttgccatag aaatggttgc tggtagcagt
     1621 agagagcact gtgcacctgg gaatgaggaa tcaggcccca agacagaagt acttggagga
     1681 gccagctgca gtagtatccg cctgtagtcc cagctactca ggaggctgag acaggaggat
     1741 tgcttaagcc caggagctca agtcccacct gggcaacata gtaagatctt gtctcttaaa
     1801 gaaaaaaaaa aaaggtactt agaggtcgca cttaaagatt atgcacatca gcagaggaaa
     1861 ggccagccaa gcttggggca agcttgatgc agtaggagag actccttatg aggcttagcc
     1921 cttgtcttac tgccagcctt tgccacaggc aggtgagaaa ggcagggcca ctcctcagca
     1981 aagttggcct cttctacact tcctcaccag tgttgtttct tccttttttc ccctcttccc
     2041 cttcccgtct tgtgtttttt ctgaacccca catctgccat catttctctc ctctagagtc
     2101 cctggcttct ggccactgcc tcctccctct tctaagcctt ggcctgaatc tggttgatca
     2161 gaggcaagtg tggatccttt gggtggcagt caggggagat ctcagggcct ctgttgggag
     2221 gaatctctgt aattcctgct tgggctccaa atttctgaag agtaatattt ttaaactata
     2281 gcttacaaaa tacattctct gaccacagtc tcctccttga tatacaaggg atggatgaag
     2341 ttcatgtatt aggactggca ctccttacgg tgcttataga actagtctca ccacttgact
     2401 cattacgtcg tcattcttgt tacatcactc atacttttag ctgcaaccac actaattcac
     2461 atttttatat actttcaatt agctgtacta attggggctt gaaagtatat aaaatcttcc
     2521 tgtcctgtga attttaaaaa gctatcccat atcgattgcc aaagagcatc taccttacct
     2581 cctaagaaga aaagccactt tcttccaatc caagcccact gcagccttgt ggattttcca
     2641 cacagcagct tttcactgta tgcctgtact tgggctgcac tgagcttgtc ttcaggaaac
     2701 cagagcgttg ctttatcatc gcacttttca tcttggtaat atcaaaacaa ctttttaaat
     2761 gaactgattg atatatgtta tttcttgcga ggttttcctc tggcctttaa ctggcttctg
     2821 aggctacaga actccaaccc agagttcttc gggacctaaa ttttgcttaa ggaaggcctt
     2881 tatcatgctg aaagcactca gacatgtctg tcctcacagc agaatgtaga agtcatatga
     2941 atgagggatc gtgcacggta gcgtcagccc gaattgacac gacaactctg aatgtgtggc
     3001 cctctatgaa agctggtgcc agttttcatc actgttatta aatactagat tgggaacctc
     3061 attcagccgt attgcacaga tgagcaatta cagcagagaa aattcattag tgctcccact
     3121 catatcctta tgtgtgagtt ggtgaaattt agcctgagct tgattcttag gtcttgagac
     3181 tcagtttcca acaccttcat tattaatgtt aagaatggcc atataccact tcatttacgt
     3241 aaaaggaata aaataagcaa gttaagcttc agggtcctag aatttttctg atttctataa
     3301 tccttcagca gaatattaag aaataaagca tgatctgcaa tggaaaggtt tttttggcac
     3361 taacttcatg cagaatttca cagacatcta tgcattaatt taaattcttg gtgcaaatgt
     3421 gtgctttgta gttcaacctt attaaaaatt cttcagccag ttaggatttc aaaatacatt
     3481 agtgagagta acagctagca gaataattac aatggctaaa acgtttttat agagaatctt
     3541 gtttttcaaa aaagaataaa aagtttgaat agctattatt aaagaaaagc catgtcttca
     3601 acatctgagt caccaagaag taacactttt taaacttgtt agaaatccct ggaggcattt
     3661 caaattcatc ttctaaccta cctaagcact ttaaaataca gcctccttct gttcctctgt
     3721 tccccttcat gcctcctttt gaattgatat ctcagctgtc aatatttctt tgacttcagc
     3781 attgttattt tatttctcta tatcaatgtg tccttagttt tcttagcctg ttaatttaaa
     3841 aatccagact tgggggtcat tgtgttgcta cccaagagaa aatgctacag ttttatagat
     3901 tgcacatcat tctttaaggc atacttttac ctcaggaaac ttactctagt atgttctcat
     3961 atattgaatt ctcaactaag taactatttc tttataccta taaactagta cctaattcac
     4021 tgttagttaa atgagctata gataaggcag ctaaatttct gaaagatagc cagagtaagt
     4081 aagcagccac tgcaagctct gaatcagttt tttaaaaaaa agaaaaaaaa aaaaaaggag
     4141 ctgtgcccca ttgaacaatg acaacatcac aaggggaagg gagggatttt gccaaaagtt
     4201 agaaaggtgg agctgtaagc catgtgcttg ttgcctttga cagtgacagt gcgcgtctta
     4261 caactaattc cactaggcat gggaatgtca cctcctttgc cactgtaccc catcaagctt
     4321 actctgaatc aaaggttttg taaaactttt gaaaatgaac ttagctgcaa aatatagcta
     4381 accactttcc attgcaagct ttgcaaagtg aagagaggtt cgtacttctc ataattggta
     4441 tttagcacaa ttgtaagata cagttttact gtttgtacat cgtttttttc cattaaactt
     4501 ttctagagaa gacaaaagct tacactggtg acatggataa gtgagatggt gtctaacgag
     4561 cagtgcaata ttaggcggtg caatagaggc cctgttggca agatgagttt tgctggagag
     4621 ctggacagtg ttggttagct tcctgcattg attgcccctg ggcgttcttc ccccttaact
     4681 gtgaaagcag agtctataaa tgaactcttt gctcttacaa ggtaatttac atattttctt
     4741 tctgttgaaa taactgaaaa tgttaaatct accagtttat gtcttgtaaa cagagtgtca
     4801 tatgtattta agttgtgtat ttttataaag taaagccaag tatcaaa
//
