LOCUS       NM_001015882            2280 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens DnaJ heat shock protein family (Hsp40) member C25
            (DNAJC25), transcript variant 1, mRNA.
ACCESSION   NM_001015882
VERSION     NM_001015882.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2280)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL135787.13 and BC048318.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001015882.2.
            
            Transcript Variant: This variant (1) represents the shorter
            transcript but encodes the functional protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.45668.1,
                                           SRR1660805.60482.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000313525.4/ ENSP00000320650.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                AL135787.13        74198-74215
            19-47               AL135787.13        74216-74244
            48-1147             BC048318.1         1-1100
            1148-2280           AL135787.13        96077-97209
FEATURES             Location/Qualifiers
     source          1..2280
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q31.3"
     gene            1..2280
                     /gene="DNAJC25"
                     /gene_synonym="bA16L21.2.1"
                     /note="DnaJ heat shock protein family (Hsp40) member C25"
                     /db_xref="GeneID:548645"
                     /db_xref="HGNC:HGNC:34187"
     exon            1..410
                     /gene="DNAJC25"
                     /gene_synonym="bA16L21.2.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..1157
                     /gene="DNAJC25"
                     /gene_synonym="bA16L21.2.1"
                     /note="DnaJ-like protein; DnaJ (Hsp40) homolog, subfamily
                     C, member 25"
                     /codon_start=1
                     /product="dnaJ homolog subfamily C member 25 precursor"
                     /protein_id="NP_001015882.2"
                     /db_xref="CCDS:CCDS43862.1"
                     /db_xref="GeneID:548645"
                     /db_xref="HGNC:HGNC:34187"
                     /translation="MGAPLLSPGWGAGAAGRRWWMLLAPLLPALLLVRPAGALVEGLY
                     CGTRDCYEVLGVSRSAGKAEIARAYRQLARRYHPDRYRPQPGDEGPGRTPQSAEEAFL
                     LVATAYETLKDEETRKDYDYMLDHPEEYYSHYYHYYSRRLAPKVDVRVVILVSVCAIS
                     VFQFFSWWNSYNKAISYLATVPKYRIQATEIAKQQGLLKKAKEKGKNKKSKEEIRDEE
                     ENIIKNIIKSKIDIKGGYQKPQICDLLLFQIILAPFHLCSYIVWYCRWIYNFNIKGKE
                     YGEEERLYIIRKSMKMSKSQFDSLEDHQKETFLKRELWIKENYEVYKQEQEEELKKKL
                     ANDPRWKRYRRWMKNEGPGRLTFVDD"
     exon            411..563
                     /gene="DNAJC25"
                     /gene_synonym="bA16L21.2.1"
                     /inference="alignment:Splign:2.1.0"
     exon            564..1034
                     /gene="DNAJC25"
                     /gene_synonym="bA16L21.2.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..2280
                     /gene="DNAJC25"
                     /gene_synonym="bA16L21.2.1"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1475
                     /gene="DNAJC25"
                     /gene_synonym="bA16L21.2.1"
                     /note="major polyA site"
     regulatory      2261..2266
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAJC25"
                     /gene_synonym="bA16L21.2.1"
                     /note="hexamer: AATAAA"
     polyA_site      2280
                     /gene="DNAJC25"
                     /gene_synonym="bA16L21.2.1"
                     /note="major polyA site"
ORIGIN      
        1 agacgggact agccgggcgc gcggctgagt gctgcagaat cgctggggtg gcagagccgc
       61 cagcgaggct ggggatgggg gcgccgctgc tctctcccgg ctggggagcc ggggctgccg
      121 gccggcgctg gtggatgctg ctggcgcccc tgctgccggc gctgctgctg gtgcggcccg
      181 cgggggccct ggtggagggg ctctactgcg gcacgcggga ctgctacgag gtgctgggcg
      241 tgagccgctc ggcgggcaag gcggagatcg cgcgggccta ccgccagctg gcccggcgct
      301 accaccctga ccgctaccgg ccccagcccg gagacgaggg ccccgggcgg acgccgcaga
      361 gcgccgagga ggctttcctg ctggtggcaa ccgcctacga gacactcaag gatgaagaaa
      421 cacgaaaaga ttatgattac atgctggatc atccagaaga gtactacagc cattactacc
      481 actactatag caggcgcttg gcccctaagg tggatgttag agtagtgatt ttggtcagcg
      541 tgtgtgctat ttcggtgttt cagtttttca gctggtggaa tagctacaat aaggcaatca
      601 gctacctagc cacagtgccc aagtaccgta tccaagctac agagattgcc aagcagcagg
      661 gactgctcaa aaaagccaaa gaaaaaggca aaaacaaaaa gtccaaagaa gaaattcgtg
      721 acgaggagga gaacatcata aagaacatta taaaaagtaa aatagatata aaggggggct
      781 atcagaaacc ccaaatctgt gatcttctcc tgtttcaaat tatcttagct ccttttcacc
      841 tatgctcata tatagtttgg tattgtcggt ggatctataa ttttaacatc aaaggcaaag
      901 aatatggaga ggaagagaga ttatacatta tacgtaaatc tatgaagatg tcaaagtctc
      961 aatttgatag tctagaagat catcagaaag aaacttttct taaacgagag ctctggatca
     1021 aggagaatta tgaggtctac aagcaagaac aagaggaaga attaaagaaa aagttggcaa
     1081 atgaccccag atggaagaga tacaggagat ggatgaagaa tgaagggcct gggcggttaa
     1141 catttgtgga tgactgaaga ttgatggaat gctactatgc caaaccttaa ttgtgatatt
     1201 attttcataa ctgaattatt ttagaaatgt atcaattgac tgctgctcag cagtaactaa
     1261 aattcctcaa gtatttgatt aaacagaata atgtcaaaat ttaaaccttc ccttaaaact
     1321 ttatacataa gacatttatg attgttcaat ttttataatc tatttgtgga ttttgttaaa
     1381 agatttcaca tgaagattta ttagttgcca tttaaaattt ttatatgttt agttaaaaga
     1441 tttgacatga aaatttatta gataccattt aaaaatttta tgtgttatgt gtttattctt
     1501 tgagaatgtt accttactgt ttgtaatagt gctacatttt tctgctttca tggcctctgt
     1561 attttcacaa aacaccaaaa acagcattta attatattat catgagtgtg tttctggaca
     1621 caaacttctg cagtagaatg acctaacatg tcgttttcat tgcagtcatt ataggattga
     1681 aatacgttca aaataacctc tctaggaaag tcttctgcta gaatttctcc cctctattca
     1741 ttataatatt ctttgttttt aaagccagtc aaatataata gtcttaataa gatcagaaac
     1801 tctccaggag agtgagtcta ccctcacgtc cttgtaggat gatcttgatt atagtcttat
     1861 tataggacta taactgtatt ctcaacattt ctccagaaag gaccttgtaa aaaggtcttt
     1921 tgtaccacag tattggtttt ttcccctctc tcttcactta aaaaaaaaaa tagcaaggca
     1981 gaaatagtgt attgaaaagt tgttcatcta ttatgaagtc cttgagtggt gaaaaatccg
     2041 ttgtacatga gaacatttct atgcatttaa gccagaaacg aggtacatgg ctgtgtgctc
     2101 ttctgtcaac caatgaaatg tgttttcaca tgtgtggcag tgcaagtaaa taacacatta
     2161 tttgactgaa tcaggcatga tactgcacca aagtgttggt acatattcac ggtagtaaat
     2221 cagtacccct gttaaaggat ttatcccatt gcttcatatt aataaaatgg ttacaatata
//
