LOCUS       NM_004125               1497 bp    mRNA    linear   PRI 17-APR-2022
DEFINITION  Homo sapiens DNAJC25-GNG10 readthrough (DNAJC25-GNG10), mRNA.
ACCESSION   NM_004125
VERSION     NM_004125.4
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1497)
  AUTHORS   Prakash T, Sharma VK, Adati N, Ozawa R, Kumar N, Nishida Y,
            Fujikake T, Takeda T and Taylor TD.
  TITLE     Expression of conjoined genes: another mechanism for gene
            regulation in eukaryotes
  JOURNAL   PLoS ONE 5 (10), e13284 (2010)
   PUBMED   20967262
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1497)
  AUTHORS   Humphray SJ, Oliver K, Hunt AR, Plumb RW, Loveland JE, Howe KL,
            Andrews TD, Searle S, Hunt SE, Scott CE, Jones MC, Ainscough R,
            Almeida JP, Ambrose KD, Ashwell RI, Babbage AK, Babbage S, Bagguley
            CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beasley H,
            Beasley O, Bird CP, Bray-Allen S, Brown AJ, Brown JY, Burford D,
            Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Chen Y,
            Clarke G, Clark SY, Clee CM, Clegg S, Collier RE, Corby N, Crosier
            M, Cummings AT, Davies J, Dhami P, Dunn M, Dutta I, Dyer LW,
            Earthrowl ME, Faulkner L, Fleming CJ, Frankish A, Frankland JA,
            French L, Fricker DG, Garner P, Garnett J, Ghori J, Gilbert JG,
            Glison C, Grafham DV, Gribble S, Griffiths C, Griffiths-Jones S,
            Grocock R, Guy J, Hall RE, Hammond S, Harley JL, Harrison ES, Hart
            EA, Heath PD, Henderson CD, Hopkins BL, Howard PJ, Howden PJ,
            Huckle E, Johnson C, Johnson D, Joy AA, Kay M, Keenan S, Kershaw
            JK, Kimberley AM, King A, Knights A, Laird GK, Langford C, Lawlor
            S, Leongamornlert DA, Leversha M, Lloyd C, Lloyd DM, Lovell J,
            Martin S, Mashreghi-Mohammadi M, Matthews L, McLaren S, McLay KE,
            McMurray A, Milne S, Nickerson T, Nisbett J, Nordsiek G, Pearce AV,
            Peck AI, Porter KM, Pandian R, Pelan S, Phillimore B, Povey S,
            Ramsey Y, Rand V, Scharfe M, Sehra HK, Shownkeen R, Sims SK, Skuce
            CD, Smith M, Steward CA, Swarbreck D, Sycamore N, Tester J, Thorpe
            A, Tracey A, Tromans A, Thomas DW, Wall M, Wallis JM, West AP,
            Whitehead SL, Willey DL, Williams SA, Wilming L, Wray PW, Young L,
            Ashurst JL, Coulson A, Blocker H, Durbin R, Sulston JE, Hubbard T,
            Jackson MJ, Bentley DR, Beck S, Rogers J and Dunham I.
  TITLE     DNA sequence and analysis of human chromosome 9
  JOURNAL   Nature 429 (6990), 369-374 (2004)
   PUBMED   15164053
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL135787.13 and BC015391.1.
            
            On Jun 2, 2019 this sequence version replaced NM_004125.3.
            
            Summary: This gene represents naturally-occurring mRNAs that are
            co-transcribed products of the neighboring DNAJC25 and GNG10 genes.
            These transcripts include the first exon of DNAJC25 and the last
            two exons of GNG10, resulting in a protein that combines the
            N-terminus of DNAJC25 and the C-terminus of GNG10. [provided by
            RefSeq, Dec 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC015391.1, ERR3218378.161848.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2142348, SAMEA2152719
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            readthrough transcript :: includes exons from GeneID 2790, 548645
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-52                AL135787.13        74198-74249
            53-1497             BC015391.1         1-1445
FEATURES             Location/Qualifiers
     source          1..1497
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q31.3"
     gene            1..1497
                     /gene="DNAJC25-GNG10"
                     /note="DNAJC25-GNG10 readthrough"
                     /db_xref="GeneID:552891"
                     /db_xref="HGNC:HGNC:37501"
     exon            1..410
                     /gene="DNAJC25-GNG10"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..536
                     /gene="DNAJC25-GNG10"
                     /note="DNAJC25-GNG10 readthrough transcript"
                     /codon_start=1
                     /product="DNAJC25-GNG10 protein precursor"
                     /protein_id="NP_004116.2"
                     /db_xref="GeneID:552891"
                     /db_xref="HGNC:HGNC:37501"
                     /translation="MGAPLLSPGWGAGAAGRRWWMLLAPLLPALLLVRPAGALVEGLY
                     CGTRDCYEVLGVSRSAGKAEIARAYRQLARRYHPDRYRPQPGDEGPGRTPQSAEEAFL
                     LVATAYETLKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFREPRSCALL"
     exon            411..542
                     /gene="DNAJC25-GNG10"
                     /inference="alignment:Splign:2.1.0"
     exon            543..1497
                     /gene="DNAJC25-GNG10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1476..1481
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAJC25-GNG10"
                     /note="hexamer: AATAAA"
     polyA_site      1497
                     /gene="DNAJC25-GNG10"
                     /note="major polyA site"
ORIGIN      
        1 agacgggact agccgggcgc gcggctgagt gctgcagaat cgctggggtg gcagagccgc
       61 cagcgaggct ggggatgggg gcgccgctgc tctctcccgg ctggggagcc ggggctgccg
      121 gccggcgctg gtggatgctg ctggcgcccc tgctgccggc gctgctgctg gtgcggcccg
      181 cgggggccct ggtggagggg ctctactgcg gcacgcggga ctgctacgag gtgctgggcg
      241 tgagccgctc ggcgggcaag gcggagatcg cgcgggccta ccgccagctg gcccggcgct
      301 accaccctga ccgctaccgg ccccagcccg gagacgaggg ccccgggcgg acgccgcaga
      361 gcgccgagga ggctttcctg ctggtggcaa ccgcctacga gacactcaag gtctctcagg
      421 cagctgcaga gcttcaacag tactgtatgc agaatgcctg caaggatgcc ctgctggtgg
      481 gtgttccagc tggaagtaac cccttccggg agcctagatc ctgtgcttta ctctgaagac
      541 tcgagagaag tttgctgagg aatgccttca agcacaaagt gatgaatgac tgccttcaag
      601 tctcaagaaa acacttttcc ctaactttta gagatatttc agccctttcc tgtggcctgg
      661 tcctatagcc aaaatcacag atattcatga gtttctactt gagtgagaaa actgggtgaa
      721 ggaatagaat tttaaatagt aataactgct tgtttttttt gtgcaagtac ttttatacat
      781 aagataaaca aaaaccttac caccaaacat accaaaatgc acctctttca taagtgagtt
      841 actaagattt ctatacctgg aatatcatgt atgtttcatt tactggatgt ttacatttta
      901 ggaaggaaaa tagttttgtt tatttaaaca actgaatact tataaactgt tgttcctgga
      961 agttatttat tccataaaaa atttgttctt ttgtcatgaa tttataattc ctaaatgaag
     1021 accagaaagt acaaattgct gggaggaaga ataggcttta ttaatcaact gatgtcttga
     1081 tttttctaaa tgggaagatt gctttatttt taacactaat tatgggagca gattcttagc
     1141 aaacttcttt ggaaaagtta atgttatgat gtgcattagg ctgccccatc gtgtatataa
     1201 atgaagcaga tttgattttt gtattcttac gtttctctgc tttgtagttg tggctgtact
     1261 taaagaaata cagaatttca tatatttaaa aatgtttaaa atgtgaccca cagaacattg
     1321 taaatgatta aaaactaaca tgaaaatatt acaacctaaa agaattctta acttcacaag
     1381 tgttttactt cgacgatgtg cctttgattt aatttgggac acttttttag aaggatacat
     1441 tattcgtgtt tgcaacggtc tttgaagagc ttggaaataa aatttctgct taattaa
//
