LOCUS       NM_018897              12419 bp    mRNA    linear   PRI 06-AUG-2024
DEFINITION  Homo sapiens dynein axonemal heavy chain 7 (DNAH7), mRNA.
ACCESSION   NM_018897
VERSION     NM_018897.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 12419)
  AUTHORS   Wilken,A., Hoben,I.M., Wolter,A., Loges,N.T., Olbrich,H., Aprea,I.,
            Dworniczak,B., Raidt,J. and Omran,H.
  TITLE     Primary Ciliary Dyskinesia Associated Disease-Causing Variants in
            CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy
            Chains DNAH1, DNAH6, and DNAH7
  JOURNAL   Cells 13 (14), 1200 (2024)
   PUBMED   39056782
  REMARK    GeneRIF: Primary Ciliary Dyskinesia Associated Disease-Causing
            Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner
            Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12419)
  AUTHORS   Gao,Y., Liu,L., Shen,Q., Fu,F., Xu,C., Geng,H., Lv,M., Li,K.,
            Tang,D., Song,B., Wu,H., Xu,Y., Zhang,Y., Tao,F., Zhou,P., Wei,Z.,
            He,X. and Cao,Y.
  TITLE     Loss of function mutation in DNAH7 induces male infertility
            associated with abnormalities of the sperm flagella and
            mitochondria in human
  JOURNAL   Clin Genet 102 (2), 130-135 (2022)
   PUBMED   35543642
  REMARK    GeneRIF: Loss of function mutation in DNAH7 induces male
            infertility associated with abnormalities of the sperm flagella and
            mitochondria in human.
REFERENCE   3  (bases 1 to 12419)
  AUTHORS   Wei,X., Sha,Y., Wei,Z., Zhu,X., He,F., Zhang,X., Liu,W., Wang,Y.
            and Lu,Z.
  TITLE     Bi-allelic mutations in DNAH7 cause asthenozoospermia by impairing
            the integrality of axoneme structure
  JOURNAL   Acta Biochim Biophys Sin (Shanghai) 53 (10), 1300-1309 (2021)
   PUBMED   34476482
  REMARK    GeneRIF: Bi-allelic mutations in DNAH7 cause asthenozoospermia by
            impairing the integrality of axoneme structure.
REFERENCE   4  (bases 1 to 12419)
  AUTHORS   Zhang,Y.J., O'Neal,W.K., Randell,S.H., Blackburn,K., Moyer,M.B.,
            Boucher,R.C. and Ostrowski,L.E.
  TITLE     Identification of dynein heavy chain 7 as an inner arm component of
            human cilia that is synthesized but not assembled in a case of
            primary ciliary dyskinesia
  JOURNAL   J Biol Chem 277 (20), 17906-17915 (2002)
   PUBMED   11877439
  REMARK    GeneRIF: These studies identify DNAH7 as an inner arm component of
            human cilia that is synthesized but not assembled in a case of
            primary ciliary dyskinesia.
REFERENCE   5  (bases 1 to 12419)
  AUTHORS   Neesen,J., Koehler,M.R., Kirschner,R., Steinlein,C.,
            Kreutzberger,J., Engel,W. and Schmid,M.
  TITLE     Identification of dynein heavy chain genes expressed in human and
            mouse testis: chromosomal localization of an axonemal dynein gene
  JOURNAL   Gene 200 (1-2), 193-202 (1997)
   PUBMED   9373155
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC114760.3, BP199399.1, AF327442.1, AC068919.4 and BX117789.1.
            
            On Nov 23, 2018 this sequence version replaced NM_018897.2.
            
            Summary: DNAH7 is a component of the inner dynein arm of ciliary
            axonemes (Zhang et al., 2002 [PubMed 11877439]).[supplied by OMIM,
            Mar 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB023161.2, AF327442.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000312428.11/ ENSP00000311273.6
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                AC114760.3         8449-8473           c
            26-607              BP199399.1         1-582
            608-10081           AF327442.1         578-10051
            10082-10082         AC068919.4         47764-47764         c
            10083-12263         AF327442.1         10053-12233
            12264-12397         AF327442.1         12237-12370
            12398-12419         BX117789.1         524-545
FEATURES             Location/Qualifiers
     source          1..12419
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q32.3"
     gene            1..12419
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /note="dynein axonemal heavy chain 7"
                     /db_xref="GeneID:56171"
                     /db_xref="HGNC:HGNC:18661"
                     /db_xref="MIM:610061"
     exon            1..141
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     CDS             127..12201
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /note="dynein, axonemal, heavy polypeptide 7; axonemal
                     dynein heavy chain 7; dynein heavy chain 7, axonemal;
                     hDHC2; ciliary dynein heavy chain 7; dynein heavy
                     chain-like protein 2; axonemal beta dynein heavy chain 7"
                     /codon_start=1
                     /product="dynein axonemal heavy chain 7"
                     /protein_id="NP_061720.2"
                     /db_xref="CCDS:CCDS42794.1"
                     /db_xref="GeneID:56171"
                     /db_xref="HGNC:HGNC:18661"
                     /db_xref="MIM:610061"
                     /translation="MSSEQDKSASKEKSKKPVRFLPQLSMEKLASKEKFKAPARALPQ
                     LSMVSTKPHWQQAAPSFHLSVKQDDESPEPFSVKNEQSHAEYMERFGKKGKLPHQVDD
                     SYVGPSTSKSKGKSPHKERENFRSTLVNVIMQQDADLDSAVPDGSTIPKPTASAIEKD
                     ILRYYYYIHHGIDTDHVAPMEDSWLEHVLDLVPQHLKVFTDSIVTLSDEMREDYLLSV
                     RKSIVDFVLKDPREKGDDKKTDELPAHRAEMEILPKPWRKSFLAASSYIRDHLNAMNP
                     TMLAVLDLWHTNFKKLRLVDIKEFHNCQDALELSSFQNIIMRHMDSAKETLLKMWFPE
                     VQNIYYQGNKKKQLPTGDSSAKLESFFNCAAALMTLQLQDLTLVSMQDFTDLIAQPPD
                     SVRAFEHPGFIMRLILDNDTIKFEPELSDYIDIFLNVYDVMIKAVSFVPRVETKLYSK
                     WESKSKPTTLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERD
                     VDNFLAENHSYEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRALVKRADI
                     ICGKLLAKMFRDHQEVNTRLCDEFERIAEKALSTPPNTAELMEMKAYIQKVEVTDMIE
                     LEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKIIKEKIEQYQ
                     EGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFN
                     AEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGPYHKVNPDQVEA
                     DIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNPGLRPRHWEA
                     MSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEKMITEWDA
                     VEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWEGKLLL
                     LQEILDEWLKVQATWLYLEPIFSSPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQDKHV
                     LTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSETKD
                     PTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEGEVVELIEIISTAKARGQVEKWLVE
                     LERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTAIPMGIK
                     ALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNISDDS
                     DFEWLSQLRYYWQENHLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGALHL
                     HLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWAC
                     FDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAG
                     RSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSS
                     QHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGIT
                     SDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGE
                     PFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSD
                     GVLAVSFRAFASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQ
                     MNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMG
                     LFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKERNDRETY
                     SLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSS
                     KALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRY
                     SALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQ
                     NIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYD
                     LKDCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILT
                     WHLEICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGV
                     CLSRPETTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHEL
                     FQRLDFDNDGMVEADDLRSLMFCDFHDPKREDTNYREIADVDNLRMIVEIHLEEYNNI
                     SKKPMNLVLFRFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQ
                     VEISKGYDTTEWHEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIP
                     NLFALDEKQEICDKMRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGD
                     AFRNRLRKFPALVNCCTIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKSFH
                     TSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLD
                     SASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQ
                     AMASKAIKDECDADLAGALPILESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAIC
                     ILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDMRFLQSLHEYDKDNIPPAYMNIIRK
                     NYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAM
                     DGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKKLERAEQLIGGLGGE
                     KTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQNQTKEWTTLCKGRDIPC
                     SDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPLMIDPQSQANKWIK
                     NMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEPLLLKQTFKQGG
                     STCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEGMQDQLLGIV
                     VAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAIKILSSSK
                     ALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQYSLTWF
                     INLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTINLLL
                     HERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMRL
                     KDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRA
                     FIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQGYGGSKLSSLSLGQG
                     QGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSYP
                     SPNFPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKLLYGL
                     CFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTGEC
                     NYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKT
                     LPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDI
                     LGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKGLA
                     VMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWYEVGPPPV
                     FWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVMEDKEYKHPPEDGVFIHGLFL
                     DGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLS
                     TTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQLNS"
     exon            142..204
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            205..267
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            268..376
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            377..524
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            525..612
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            613..793
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            794..869
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            870..995
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            996..1115
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            1116..1299
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..1479
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            1480..1752
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            1753..1880
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            1881..1959
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            1960..2184
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            2185..2331
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            2332..3017
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            3018..3204
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            3205..3398
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            3399..3597
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            3598..3738
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            3739..3951
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            3952..4061
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            4062..4230
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            4231..4333
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            4334..4461
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            4462..4674
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            4675..4773
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            4774..5022
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            5023..5172
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            5173..5355
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            5356..5532
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            5533..5664
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            5665..5889
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            5890..6087
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            6088..6243
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            6244..6412
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            6413..6539
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            6540..6759
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            6760..7632
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            7633..7862
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            7863..8193
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            8194..8540
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            8541..8721
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            8722..8907
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            8908..9071
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            9072..9226
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            9227..9417
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            9418..9551
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            9552..9887
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            9888..10014
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            10015..10209
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            10210..10302
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            10303..10479
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            10480..10641
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            10642..10842
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            10843..11004
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            11005..11190
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            11191..11328
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            11329..11559
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            11560..11712
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            11713..11890
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            11891..11994
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     exon            11995..12419
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /inference="alignment:Splign:2.1.0"
     regulatory      12392..12397
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /note="hexamer: AATAAA"
     polyA_site      12397
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /note="major polyA site"
     polyA_site      12419
                     /gene="DNAH7"
                     /gene_synonym="CILD50"
                     /note="major polyA site"
ORIGIN      
        1 agacggctct ggtgcggagg gagctgagac cgctgcaagt cccggggccc tgcctctatc
       61 gtcctagggg ttccgcgggc aggagcaacc cagaagcacc ggtgaggcca gcgcgtcctc
      121 gcagccatga gcagtgagca ggataaatcg gccagcaaag aaaaatccaa gaaaccagta
      181 agatttctac cacagctgtc tatggagaaa ttagccagca aagaaaagtt caaggcacca
      241 gcaagagctt taccacagct gtctatggtg agtacaaagc cccactggca gcaggcagct
      301 ccatcattcc atttgagtgt aaagcaggat gatgagagtc cagaaccatt tagtgttaaa
      361 aatgaacagt cccatgctga atacatggaa cgttttggaa aaaagggcaa attaccccac
      421 caagttgatg atagttatgt tggaccatct acttccaaat caaagggcaa atctccacat
      481 aaagaacgag aaaactttag aagtactctt gttaatgtca ttatgcaaca agatgctgac
      541 ttagactcag ctgtccctga tggaagcaca attccaaaac cgaccgcttc tgctatagag
      601 aaagacatct tgagatatta ctattatatt caccatggaa ttgatacaga ccatgtagcc
      661 ccaatggaag attcttggct agaacacgta ctggatttag ttccacaaca tctgaaagtc
      721 ttcactgaca gcatagttac attatctgat gaaatgagag aggattatct tcttagtgta
      781 aggaaatcca tagttgattt tgttttaaaa gatcctcgag agaaaggaga tgataagaag
      841 acagatgaac ttccagccca tcgtgctgaa atggaaattc tgccaaaacc ttggaggaaa
      901 tcttttttag ctgcaagcag ttatattagg gatcacttga atgcaatgaa ccccacaatg
      961 ctggctgtac tagatttgtg gcacactaat tttaaaaaat tacgtttagt tgatatcaaa
     1021 gaatttcata attgccagga tgcattagag ctgtcaagtt ttcagaacat tatcatgaga
     1081 cacatggact ctgccaaaga gactctactt aaaatgtggt ttccagaagt gcagaatatt
     1141 tattaccaag gtaataaaaa aaagcaattg ccaactggtg acagcagtgc caaattggaa
     1201 tcttttttca actgtgctgc tgcacttatg actttacagc tgcaggacct cactttagtc
     1261 tccatgcaag atttcacgga cttaattgca caacccccag attctgttag agcttttgaa
     1321 catccaggtt tcatcatgag gctgattctt gataatgaca ccattaagtt tgaacctgag
     1381 ttgagtgact atatagatat ctttctaaat gtttatgacg tcatgattaa agctgtcagt
     1441 tttgtgccaa gagttgagac aaaattgtat tccaagtggg aaagtaagtc taaaccaaca
     1501 accttgaagc ccataattct gaatgaaatt gtagatgctc acaaagaaaa gatcaaggaa
     1561 gttattatga aagagagtgt ggcacctact gagcacctca gactctatga caagtatgac
     1621 tttttaatta ccagaaaagc tgagcgagat gttgataact tcctcgcaga aaatcatagt
     1681 tatgaaaaaa taatagatga aatttgcaaa taccagaaac taatagagga aatacagtac
     1741 acatccataa agactattcg tttaggaatg tttgaaatgc actgtgagga attaatcaga
     1801 gctttggtga agcgagcaga tattatttgt gggaaacttc tagctaaaat gttcagagat
     1861 catcaggaag taaatacaag attatgcgat gaatttgaga ggatagctga aaaagctctt
     1921 agcactcctc caaatacagc agaactaatg gaaatgaagg cttacattca gaaagtggag
     1981 gtaactgata tgattgaact agaacagaga ttagtggatt ccaaaaactg cctcgccttc
     2041 ctcatcgagt atgtcaactt ttctccagca gacatgaggc taaataatag tgttttccag
     2101 tggtatggaa ggatgggaga aatttttgaa gaacacagga aaatcattaa agagaaaata
     2161 gaacaatatc aagaaggtct gaagttacgg tgtgaacggt ttgtggagga attggagagt
     2221 tatgctaagc aatcagaaga attttattca tttggagatc ttcaggatgt tcagcggtac
     2281 ctaaaaaagg ctcaaatact gaatggaaag ttggatttag ctgcagataa gattgagcag
     2341 tttaatgctg aagaggaagc atttggttgg ctaccatctg tatatcctca acgtaaaaaa
     2401 atccaagatg gcttgaaccc ttatcttcgt ctttatgaaa ctgctgtcga atttagcagc
     2461 aactatagag catggacaga agggccatat cataaagtga atccagacca agtagaagca
     2521 gatattggaa attactggag aggattatat aaactggaga aaacctttca tgattctcca
     2581 tatgcattgg caatgacaaa aaaagtaaga tcaaaggtgg aagatttcaa gcagcacatt
     2641 cctctcattc aagtgatctg taatcctggt ttgcgcccca ggcactggga ggccatgtct
     2701 gccattgttg gttacccttt gcagccatca gatgactcca cagtctcctc ttttttagac
     2761 atgaatctgg aaccatatat agaccgattt gaaggtatta gtgaagcagc tagcaaagaa
     2821 tattctcttg aaaaggcgat ggagaagatg attactgagt gggatgcagt ggaatttgtc
     2881 atccattctt atagagaaac tgggacattt attttggcat cagttgatga aattcagatg
     2941 ttgttggatg accatattat taaaacacaa actatgcgag gatctccttt cattaagcct
     3001 tatgaaaaac aaatgagaga atgggagggc aagctcctac tgcttcagga gattctggat
     3061 gaatggctca aagtccaagc cacgtggctg tatctggagc ccattttcag ctctccagac
     3121 attatgtctc aaatgcctga ggaaggcaga cgatttacag ctgtggataa gacatggaga
     3181 gatataatga gaagtgtcat gcaggataaa catgttctga cagttgtaac cattgacaga
     3241 atgctggaaa ggctgaaaaa atctaatgaa cttttggagc tcattcttaa aggacttaat
     3301 gaatatttgg aaaagaaacg cctctttttc cccagattct tttttttgtc caatgatgaa
     3361 cttcttgaga tactatctga gactaaagat cccactaggg tgcaacctca cttgaagaaa
     3421 tgttttgaag gaatcgcaaa ggtagaattt acggaaactt tagacattac tcacatgaag
     3481 agcagcgaag gagaggttgt agaactcata gagattattt caacagccaa agccagaggt
     3541 caagtggaga agtggttggt tgaattagag agagttatga ttaactccat ccacaaggta
     3601 actggagatg caacttttgc ctatacaaaa tatgaacgaa ttaactgggt aagggattgg
     3661 cctggacaga ctgttctctg tgtatcccaa atcttttgga caaaagaagt acaaacagct
     3721 attccaatgg ggataaaggc tcttgagcaa tacttgaaaa catgtaacag acaaattgat
     3781 gatattgtca ctttggtgcg tggcaaattg tccatgcaga atcgcgtaac tctgggagca
     3841 cttgtggtac tggatgtcca tgctagagat gtcctctcat cacttgtaaa aaaaaatatt
     3901 agcgatgact ctgactttga atggttaagt cagcttaggt actactggca agaaaatcat
     3961 ttagaaacaa aaatgatcaa tgctggtttg cgatatggat atgaatatct gggtaattcc
     4021 cctaggctgg ttattacacc actcacggat agatgttaca gaaccttatt tggagccctt
     4081 catttgcacc ttggaggagc acctgagggt ccagctggca ctgggaagac tgaaactacc
     4141 aaggatttgg caaaagctgt agccaaacaa tgtgttgttt tcaactgctc tgatgggttg
     4201 gattatttgg ctttgggaaa attctttaag ggactgttat cttgtggagc ctgggcttgc
     4261 tttgatgagt ttaacagaat tgatttggaa gtactctctg tggttgctca acaaatcctt
     4321 actatccaaa gaggtattaa tgcaggtgct gatatactga tgtttgaagg aactgaacta
     4381 aaacttgacc ccacatgtgc tgtctttata acaatgaacc ctgggtatgc tgggcgatca
     4441 gaactgccag ataacctgaa ggctctcttt cggacagtag caatgatggt acctgactat
     4501 gccatgattg ctgaaatagt cctatactcc tgtgggtttg tcactgctcg accactgtct
     4561 gtaaaaattg tggctacgta tcgcttgtgt tcagagcagc tgtcatctca acatcactac
     4621 gactatggaa tgagagccgt gaagtcagtt cttactgctg ctgggaatct gaagctgaaa
     4681 tatccaaatg aaaatgaaga aattttgctg cttagatcta tcattgatgt aaatctgcca
     4741 aaatttttat cccatgattt accactcttt gagggaatta cttcggattt gtttcctggg
     4801 gtaaaattac caaaaccaga ttacaatgat ttgctggcag ctatcaaaga caattgtgcc
     4861 tccatgaatt tgcaaatgac tgcattcttt tccgagaaga ttcttcaagt atatgaaatg
     4921 atgattgtgc gtcatggttt tatgattgtt ggagaaccat ttggaggaaa aactagtgca
     4981 tatcgtgtct tagctggagc actaaatgat atatgtgaaa aggggctaat ggaagaaaac
     5041 aaagttcaaa taactgtttt aaatcctaag tctgtcacca tgggccaact gtacggacag
     5101 tttgattcag tgtcccatga atggtctgat ggggtccttg ctgtcagttt tagagcattt
     5161 gcctcttcag tgactccaga taggaaatgg ttaatttttg atggcccagt agatgcagtg
     5221 tggattgaga atatgaacac tgtgctggat gacaacaaga agctatgtct gatgagtggg
     5281 gagattattc agatgtcacc acaaatgaat ctaatttttg agccaatgga tttagaagtt
     5341 gcttcccctg ccactgtttc cagatgtggc atgatttaca tggagcctca catgttaggc
     5401 tggagaccac tgatgttgtc ctgggtgaat ctgttacctg cgtcagtcag tgttattcaa
     5461 aaggaattca taatgggctt atttgacaga atggtccctg tttcggttga atttattaga
     5521 aagcatacaa aggaattatc tcctacttcc gatacaaact tggtccggtc cttaatgaat
     5581 ctaatagact gttttatgga tgattttgct gatgaagtca aactaaagga gagaaatgat
     5641 cgagaaactt actctttgct tgagggcatt tttctgtttt cattgatctg gtccgttggt
     5701 gcttcttgta cagatgatga tcgattgaaa tttaataaga ttcttcgaga actaatggaa
     5761 agtccaattt cagatcgaac tcgaaatacg tttaaattac agagtggtac tgagcaaaca
     5821 tcctcaaagg cactaactgt cccatttcct gaaaaaggaa caatttatga ttatcaattt
     5881 gtcactgagg gaataggaaa atgggaacca tggataaaga aattgaaaga agctcctcca
     5941 attcctaaag atgtaatgtt taatgaaatc attgtgccaa ctctggacac aattcgatac
     6001 tctgcattaa tggaattgct gaccacccat caaaagcctt caatatttgt aggaccaaca
     6061 ggaactggga aaagtgttta cattacgaat tttcttttaa atcaactaaa taaggaaatc
     6121 tacaaacctc tgctaattaa cttctcagca caaactacag cagctcaaac tcagaatatt
     6181 gtcatgtcaa aattggacaa gagaagaaag ggagtttttg gtcctccttt gggcaagaga
     6241 atggttgtct ttgtagatga tgtcaatatg cctgctcggg aggtatatgg ggctcaacct
     6301 cccattgagt tacttagaca gtggttagac cactggaact ggtatgatct aaaagattgt
     6361 tccatgatta aactagtgga cattcagatc atgtgtgcta tgggacctcc aggtggtggt
     6421 cgaaatccag taactcctcg atacatgcga catttcaata ttataacaat caatgagttt
     6481 agtgataaat ccatgtatac aatcttctct agaatcttaa cttggcattt agaaatctgt
     6541 tataaatttc cagatgaatt tctagatttg accacacaaa tcgtaaatgg cacaatgact
     6601 ctgtataaag aagcaatgaa gaatctcttg cctactccag ctaaatctca ctacttgttc
     6661 aacctccgtg atttctcccg tgtcattcaa ggtgtttgtt tgtcaagacc agaaacaaca
     6721 gaaaccacag aagtgattaa acgtctttgg gttcatgagg tccttcgagt gtattatgac
     6781 cgccttctgg acaatacaga cagaagctgg ctcatcaact acattcaaga aattttgaga
     6841 aactacatgt atgaagattt tcatgagctt tttcagcgtt tggattttga taatgatggc
     6901 atggtggaag cagatgactt acgcagctta atgttttgtg atttccatga tcccaagagg
     6961 gaggatacca actacagaga aatcgcagat gtggataatc ttcgaatgat agtagaaatt
     7021 cacctagaag aatacaacaa tataagcaaa aaacccatga accttgtctt gtttcgattt
     7081 gccatagagc acatcagcag aatttccagg atcctgaagc agcctcgcag ccatgctctc
     7141 ctagtagggg ttggagggag tggaaggcag tctgtcacca gattagctgc ccacatggct
     7201 gattattcag ttttccaagt tgaaatctct aaggggtatg atactactga atggcatgaa
     7261 gatttaaaag tgatcttaag gaaatgtgcg gaaggtgaga tgcagggtgt cttcctgttt
     7321 acagatactc aaattaaaga agagtctttt ctggaagatg tcagtaatct gctaaatgct
     7381 ggggagattc caaatctctt tgcattagat gagaagcaag agatatgtga taagatgcgt
     7441 cagttagatc gccagcggga taaaaccaag caaacagatg gcagccccat agcccttttc
     7501 aacatgttta ttgatcattg ccgcagccaa ctgcatgtgg tccttgccat gagtcccatt
     7561 ggagatgcat ttcggaatcg tcttagaaag ttccctgctc ttgttaactg ctgtaccatt
     7621 gactggtttc agtcatggcc tgaagatgca ctccaggcag ttgcctcacg attcttggaa
     7681 gaaattgaaa tgtcagagga aatacgagat ggctgtatcg acatgtgtaa aagcttccac
     7741 acttctacta tagatttatc caaatctttc tttgttgaac ttcaaagata caattatgtg
     7801 actcctacct cttacctcga attaatctcc accttcaaac tgttgttaga aaagaaaaga
     7861 agtgaagtaa tgaaaatgaa aaagagatat gaagtgggtt tggagaaact ggattctgct
     7921 tcatctcaag tagccacaat gcagatggag ttggaggcac tacatcctca attaaaagtt
     7981 gctagcaaag aggttgatga aatgatgata atgattgaga aagagtctgt agaagttgcc
     8041 aaaactgaaa aaatagtgaa agctgatgaa acaatagcga atgaacaagc tatggcttcc
     8101 aaagccatca aagatgagtg cgatgctgac ctggcaggtg ccttgccaat attagagtca
     8161 gcactggccg cccttgatac tcttactgca caggatatta cagtggtaaa atccatgaag
     8221 agtcctcctg ctggtgtcaa gcttgttatg gaagctatat gcatcttgaa aggaatcaaa
     8281 gctgacaaaa tccctgaccc aacaggttca gggaaaaaaa ttgaggattt ctggggccca
     8341 gctaagagac ttcttggtga catgaggttt ctgcagtcac ttcatgaata tgacaaggac
     8401 aatattcctc cagcttatat gaatatcata agaaaaaatt atattccaaa tccagatttt
     8461 gtaccagaaa aaatcagaaa tgcttctaca gcggccgaag gtctgtgcaa atgggtcata
     8521 gcaatggatt catatgataa agtggcaaaa atagtagctc ccaaaaagat aaaactggct
     8581 gcagctgaag gggagcttaa aattgccatg gatggtctta gaaagaagca ggcagccctt
     8641 aaggaagttc aggacaagct ggccaggctt caagacacac ttgaattaaa taaacaaaag
     8701 aaggctgacc tggaaaacca ggttgacctt tgcagcaaaa aactagaacg agctgaacag
     8761 ttgattggag gccttggagg tgagaaaact cgatggagcc acacagctct ggagctaggt
     8821 cagctgtaca tcaacttgac tggggatatc ctcatttcct ccggagtggt tgcttacctc
     8881 ggagccttca catccaccta tagacagaat caaactaaag agtggacaac tttgtgcaaa
     8941 ggaagagata tcccctgctc agatgattgc tctcttatgg gtaccctggg agaagctgtg
     9001 acaattcgaa cttggaatat tgctggatta ccttctgact cattttccat tgataatggg
     9061 ataatcataa tgaatgcaag aaggtggcct ctgatgatag atcctcaaag tcaggctaat
     9121 aaatggatca agaacatgga aaaagccaat agtctttatg tgattaaact tagtgaacct
     9181 gactatgtca ggactctgga aaattgcatc cagtttggta ctcctgtgtt gctagaaaat
     9241 gttggcgaag aactagatcc tattttggaa cctcttctac taaaacaaac ctttaagcag
     9301 ggtgggagta catgtatccg gcttggggac tccacaattg aatatgcacc tgacttccgc
     9361 ttctatatta ctaccaagtt aagaaatcct cattatcttc ctgaaacatc agtaaaggta
     9421 acattattaa acttcatgat aacccctgag ggaatgcaag atcagcttct gggaattgtg
     9481 gtggcacaag aaaggccaga ccttgaagaa gaaaagcaag ccttgatatt acaaggagct
     9541 gaaaataaaa ggcagttaaa agaaatagaa gacaagattt tagaagttct ttcatcttcg
     9601 gaaggcaata tattagaaga tgaaactgct attaagatat tatcttcctc caaggccttg
     9661 gctaatgaga tttctcagaa gcaggaagta gccgaagaga cagagaaaaa gattgacacc
     9721 acccgcatgg gctatcgtcc tattgccatc cattcttcca tcctattttt ttctcttgct
     9781 gatttagcca acattgagcc catgtaccag tattcactga cctggtttat taaccttttc
     9841 atcctgtcta ttgaaaattc agagaaatca gaaattttgg caaaaaggct tcagattctc
     9901 aaggatcact ttacttattc actgtatgtt aatgtctgcc ggtcactctt tgaaaaggat
     9961 aagctgctct tttccttttg tctaaccata aatctactgc tgcatgagcg ggcgattaat
    10021 aaagctgagt ggagatttct gctaactggt ggcattggac tggataatcc ttatgccaac
    10081 ctttgtacat ggcttcctca gaaatcctgg gatgaaatat gtcgattaga tgatttgcct
    10141 gccttcaaaa ccattcgtag agagtttatg cgcttaaagg atggatggaa gaaagtatat
    10201 gatagtttgg aaccacacca tgaggttttc cctgaagaat gggaagataa agcaaatgag
    10261 tttcaaagga tgcttattat tcgttgcttg aggccagaca aggttattcc aatgttgcag
    10321 gaatttataa tcaacagatt gggacgtgca ttcattgaac cacccccctt tgatttagcc
    10381 aaggcatttg gagacagtaa ctgctgtgca ccactgattt tcgtgctctc tcctggagca
    10441 gatcccatgg ctgcccttct aaaatttgct gatgaccagg gatatggggg atcaaaactt
    10501 agctctttat ctcttggtca aggccaaggg cccattgcta tgaagatgtt agaaaaagct
    10561 gtcaaggaag gaacatgggt tgttcttcag aattgtcacc ttgccacctc ttggatgcca
    10621 acccttgaga aagtctgtga ggagttaagc ccagagtcaa cacatccaga tttccgaatg
    10681 tggctaacga gttacccatc tccaaatttc cctgtgtcag tactgcagaa tggagtgaaa
    10741 atgaccaatg aagcaccaaa aggtttacgg gctaatatca ttcgatcata cctcatggac
    10801 ccgatctctg atccggagtt ctttggcagc tgcaaaaagc ctgaggaatt caagaaattg
    10861 ctttatggcc tgtgtttctt tcatgctttg gtacaagaaa gacggaaatt tggaccccta
    10921 gggtggaata ttccttatga gttcaatgag acagatctga gaatcagcgt acagcagctc
    10981 cacatgttcc tgaaccagta tgaggaactg ccgtatgagg ctctgcggta catgactggc
    11041 gaatgcaatt acggaggcag agtgaccgat gactgggacc ggcgcacgct gcgcagcatt
    11101 ctaaacaaat tcttcaatcc cgaattagtt gaaaattcag actataagtt cgactcaagt
    11161 ggcatctatt ttgttcctcc ttctggtgat cacaaaagct acatcgaata cacaaagact
    11221 ctgccactga ccccagcacc agaaatcttt gggatgaatg ccaatgcaga tatcactaag
    11281 gatcagtcag aaactcagct gctatttgat aacattcttc ttacacagtc tcgttcagca
    11341 ggtgctggtg caaaatcatc agatgaagta gtgaatgagg tcgctagtga catcttgggc
    11401 aaacttccaa acaacttcga catcgaggct gccatgagga ggtacccaac aacttatact
    11461 cagagcatga acactgtact tgtccaagag atgggacggt tcaataagtt actgaagacc
    11521 ataagagatt cgtgcgtaaa tattcaaaaa gcaatcaagg ggcttgcagt catgtctaca
    11581 gatcttgaag aagtggttag cagcattttg aatgtcaaaa ttccagaaat gtggatgggt
    11641 aaatcctacc caagccttaa accacttggc agctatgtga atgacttcct tgcaagacta
    11701 aaattcttgc agcaatggta tgaggttggt cctcctccag tcttctggct ttctggcttc
    11761 ttcttcacac aagccttcct gaccggtgcc cagcagaact acgccaggaa atacacaatt
    11821 cctattgatc ttcttgggtt tgactatgaa gtgatggaag acaaagaata caagcatcct
    11881 cctgaggatg gtgttttcat tcacggatta tttctggatg gagcttcctg gaatagaaag
    11941 atcaagaaac ttgcagaatc gcatcccaaa attctttatg atacagtgcc tgtgatgtgg
    12001 ctaaagccct gtaagagggc agatatacca aaacggccaa gttatgttgc tccattgtat
    12061 aagacaagtg agcggagagg agtattatcc accactggcc attccacgaa ttttgtgatt
    12121 gccatgactc ttccctctga ccaacccaag gaacactgga ttggacgagg tgtagcactg
    12181 ttatgtcaac ttaattcata accagaagac atcatttcct tgttcctatt tcttgttggc
    12241 tggctgagta gagaaagcat attttactac ttaaaccttt ttttttgttt gtttaaatac
    12301 atttgactaa agttataatt atgaatttac ttatgagcaa atgcagctaa acttaatatg
    12361 actcatactt aaatgtaagg aaatgttctg aaataaagac taaagaaaac acactggca
//
