LOCUS       NM_001370              12752 bp    mRNA    linear   PRI 29-APR-2025
DEFINITION  Homo sapiens dynein axonemal heavy chain 6 (DNAH6), mRNA.
ACCESSION   NM_001370
VERSION     NM_001370.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 12752)
  AUTHORS   Wilken,A., Hoben,I.M., Wolter,A., Loges,N.T., Olbrich,H., Aprea,I.,
            Dworniczak,B., Raidt,J. and Omran,H.
  TITLE     Primary Ciliary Dyskinesia Associated Disease-Causing Variants in
            CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy
            Chains DNAH1, DNAH6, and DNAH7
  JOURNAL   Cells 13 (14), 1200 (2024)
   PUBMED   39056782
  REMARK    GeneRIF: Primary Ciliary Dyskinesia Associated Disease-Causing
            Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner
            Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12752)
  AUTHORS   Shao,Z.M., Zhu,Y.T., Gu,M., Guo,S.C., Yu,H., Li,K.K., Tang,D.D.,
            Xu,Y.P. and Lv,M.R.
  TITLE     Novel variants in DNAH6 cause male infertility associated with
            multiple morphological abnormalities of the sperm flagella (MMAF)
            and ICSI outcomes
  JOURNAL   Asian J Androl 26 (1), 91-98 (2024)
   PUBMED   37594300
  REMARK    GeneRIF: Novel variants in DNAH6 cause male infertility associated
            with multiple morphological abnormalities of the sperm flagella
            (MMAF) and ICSI outcomes.
REFERENCE   3  (bases 1 to 12752)
  AUTHORS   Huang,F., Zeng,J., Liu,D., Zhang,J., Liang,B., Gao,J., Yan,R.,
            Shi,X., Chen,J., Song,W. and Huang,H.L.
  TITLE     A novel frameshift mutation in DNAH6 associated with male
            infertility and asthenoteratozoospermia
  JOURNAL   Front Endocrinol (Lausanne) 14, 1122004 (2023)
   PUBMED   37424858
  REMARK    GeneRIF: A novel frameshift mutation in DNAH6 associated with male
            infertility and asthenoteratozoospermia.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 12752)
  AUTHORS   Tu,C., Nie,H., Meng,L., Yuan,S., He,W., Luo,A., Li,H., Li,W.,
            Du,J., Lu,G., Lin,G. and Tan,Y.Q.
  TITLE     Identification of DNAH6 mutations in infertile men with multiple
            morphological abnormalities of the sperm flagella
  JOURNAL   Sci Rep 9 (1), 15864 (2019)
   PUBMED   31676830
  REMARK    GeneRIF: Identification of DNAH6 mutations in infertile men with
            multiple morphological abnormalities of the sperm flagella.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 12752)
  AUTHORS   Blue,E., Louie,T.L., Chong,J.X., Hebbring,S.J., Barnes,K.C.,
            Rafaels,N.M., Knowles,M.R., Gibson,R.L., Bamshad,M.J. and
            Emond,M.J.
  CONSRTM   U.S. National Heart, Lung, and Blood Institute "Grand Opportunity"
            Exome Sequencing Project (LungGO)
  TITLE     Variation in Cilia Protein Genes and Progression of Lung Disease in
            Cystic Fibrosis
  JOURNAL   Ann Am Thorac Soc 15 (4), 440-448 (2018)
   PUBMED   29323929
  REMARK    GeneRIF: Genetic variants within DNAH6, DNAH14, and DNAAF3 are
            associated with variation in lung function among persons with
            cystic fibrosis.
REFERENCE   6  (bases 1 to 12752)
  AUTHORS   Geller,F., Feenstra,B., Carstensen,L., Pers,T.H., van Rooij,I.A.,
            Korberg,I.B., Choudhry,S., Karjalainen,J.M., Schnack,T.H.,
            Hollegaard,M.V., Feitz,W.F., Roeleveld,N., Hougaard,D.M.,
            Hirschhorn,J.N., Franke,L., Baskin,L.S., Nordenskjold,A., van der
            Zanden,L.F. and Melbye,M.
  TITLE     Genome-wide association analyses identify variants in developmental
            genes associated with hypospadias
  JOURNAL   Nat Genet 46 (9), 957-963 (2014)
   PUBMED   25108383
REFERENCE   7  (bases 1 to 12752)
  AUTHORS   Bush,A. and Hogg,C.
  TITLE     Primary ciliary dyskinesia: recent advances in epidemiology,
            diagnosis, management and relationship with the expanding spectrum
            of ciliopathy
  JOURNAL   Expert Rev Respir Med 6 (6), 663-682 (2012)
   PUBMED   23234452
  REMARK    Review article
REFERENCE   8  (bases 1 to 12752)
  AUTHORS   Pazour,G.J., Agrin,N., Walker,B.L. and Witman,G.B.
  TITLE     Identification of predicted human outer dynein arm genes:
            candidates for primary ciliary dyskinesia genes
  JOURNAL   J Med Genet 43 (1), 62-73 (2006)
   PUBMED   15937072
REFERENCE   9  (bases 1 to 12752)
  AUTHORS   Maiti,A.K., Mattei,M.G., Jorissen,M., Volz,A., Zeigler,A. and
            Bouvagnet,P.
  TITLE     Identification, tissue specific expression, and chromosomal
            localisation of several human dynein heavy chain genes
  JOURNAL   Eur J Hum Genet 8 (12), 923-932 (2000)
   PUBMED   11175280
REFERENCE   10 (bases 1 to 12752)
  AUTHORS   Vaughan,K.T., Mikami,A., Paschal,B.M., Holzbaur,E.L., Hughes,S.M.,
            Echeverri,C.J., Moore,K.J., Gilbert,D.J., Copeland,N.G.,
            Jenkins,N.A. and Vallee,R.B.
  TITLE     Multiple mouse chromosomal loci for dynein-based motility
  JOURNAL   Genomics 36 (1), 29-38 (1996)
   PUBMED   8812413
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC096770.3, AC109827.4,
            AC098975.3 and AC010087.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Aug 1, 2019 this sequence version replaced NM_001370.1.
            
            Summary: This gene belongs to the dynein family, whose members
            encode large proteins that are constituents of the
            microtubule-associated motor protein complex. This complex is
            composed of dynein heavy, intermediate and light chains, which can
            be axonemal or cytoplasmic. This protein is an axonemal dynein
            heavy chain. It is involved in producing force for ciliary beating
            by using energy from ATP hydrolysis. Mutations in this gene may
            cause primary ciliary dyskinesia (PCD) as well as heterotaxy.
            [provided by RefSeq, Jun 2016].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2148874,
                              SAMEA2151119 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000389394.8/ ENSP00000374045.3
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                AC096770.3         101896-101981
            87-319              AC096770.3         103217-103449
            320-493             AC096770.3         110963-111136
            494-756             AC096770.3         114302-114564
            757-1024            AC096770.3         129631-129898
            1025-1159           AC096770.3         132666-132800
            1160-1280           AC096770.3         132890-133010
            1281-1410           AC096770.3         133686-133815
            1411-1579           AC096770.3         135287-135455
            1580-1696           AC096770.3         138316-138432
            1697-1897           AC096770.3         143133-143333
            1898-2018           AC096770.3         158865-158985
            2019-2170           AC096770.3         162655-162806
            2171-2323           AC096770.3         164925-165077
            2324-2575           AC096770.3         169397-169648
            2576-2704           AC096770.3         174224-174352
            2705-2818           AC096770.3         179370-179483
            2819-2962           AC096770.3         181044-181187
            2963-3175           AC096770.3         189737-189949
            3176-3268           AC096770.3         190898-190990
            3269-3388           AC096770.3         192374-192493
            3389-3569           AC109827.4         1395-1575
            3570-3666           AC109827.4         6607-6703
            3667-3886           AC109827.4         9406-9625
            3887-4051           AC109827.4         10912-11076
            4052-4165           AC109827.4         11159-11272
            4166-4291           AC109827.4         13986-14111
            4292-4447           AC109827.4         14186-14341
            4448-4609           AC109827.4         14623-14784
            4610-4747           AC109827.4         24225-24362
            4748-4915           AC109827.4         26931-27098
            4916-5064           AC109827.4         30151-30299
            5065-5172           AC109827.4         31668-31775
            5173-5728           AC109827.4         43040-43595
            5729-5851           AC109827.4         44381-44503
            5852-6034           AC098975.3         1874-2056
            6035-6178           AC098975.3         2608-2751
            6179-6400           AC098975.3         12871-13092
            6401-6548           AC098975.3         13910-14057
            6549-6706           AC098975.3         15909-16066
            6707-6838           AC098975.3         20587-20718
            6839-7010           AC098975.3         24939-25110
            7011-7157           AC010087.3         201312-201458       c
            7158-7231           AC010087.3         200227-200300       c
            7232-7386           AC010087.3         198191-198345       c
            7387-7618           AC010087.3         192304-192535       c
            7619-7771           AC010087.3         189057-189209       c
            7772-7912           AC010087.3         187050-187190       c
            7913-8155           AC010087.3         185445-185687       c
            8156-8323           AC010087.3         183222-183389       c
            8324-8559           AC010087.3         182482-182717       c
            8560-8821           AC010087.3         181037-181298       c
            8822-8945           AC010087.3         179765-179888       c
            8946-9142           AC010087.3         179068-179264       c
            9143-9346           AC010087.3         177238-177441       c
            9347-9472           AC010087.3         176372-176497       c
            9473-9637           AC010087.3         173525-173689       c
            9638-9705           AC010087.3         171157-171224       c
            9706-9886           AC010087.3         168400-168580       c
            9887-10066          AC010087.3         163980-164159       c
            10067-10300         AC010087.3         158882-159115       c
            10301-10436         AC010087.3         153205-153340       c
            10437-10606         AC010087.3         141535-141704       c
            10607-10797         AC010087.3         123839-124029       c
            10798-10958         AC010087.3         105131-105291       c
            10959-11047         AC010087.3         101974-102062       c
            11048-11194         AC010087.3         101028-101174       c
            11195-11333         AC010087.3         99482-99620         c
            11334-11453         AC010087.3         90359-90478         c
            11454-11575         AC010087.3         89126-89247         c
            11576-11705         AC010087.3         80990-81119         c
            11706-11833         AC010087.3         78242-78369         c
            11834-12019         AC010087.3         74258-74443         c
            12020-12092         AC010087.3         73654-73726         c
            12093-12244         AC010087.3         72662-72813         c
            12245-12467         AC010087.3         70701-70923         c
            12468-12752         AC010087.3         67195-67479         c
FEATURES             Location/Qualifiers
     source          1..12752
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p11.2"
     gene            1..12752
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /note="dynein axonemal heavy chain 6"
                     /db_xref="GeneID:1768"
                     /db_xref="HGNC:HGNC:2951"
                     /db_xref="MIM:603336"
     exon            1..86
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            87..319
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..12571
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /note="dynein, axonemal, heavy polypeptide 6; dynein heavy
                     chain-like 1; ciliary dynein heavy chain 6; axonemal beta
                     dynein heavy chain 6"
                     /codon_start=1
                     /product="dynein axonemal heavy chain 6"
                     /protein_id="NP_001361.1"
                     /db_xref="CCDS:CCDS46348.1"
                     /db_xref="GeneID:1768"
                     /db_xref="HGNC:HGNC:2951"
                     /db_xref="MIM:603336"
                     /translation="MTFRATDSEFDLTNIEEYAENSALSRLNNIKAKQRVSYVTSTEN
                     ESDTQILTFRHITKAQEKTRKRQQPIKLEPLPVLKVYQDHKQPEYIHEQNRFQLMTAG
                     IIKRPVSIAKKSFATSSTQFLEHQDAVKKMQIHRPYVEVFSPSPPKLPHTGIGKRGLF
                     GTRSSAYPKYTFHDREEVVKANIRDPLQIIKIIRENEHLGFLYMIPAVPRSSIEYDTY
                     NLKVVSYENINKNDYYTISQRAVTHIYNEDIEFIEIDRWEQEYLYHRELTKIPIFSLF
                     RKWKAFSVWRKNVRSKKITGCQKSLQKNLFIVNPHLRPALLKINELCYHLSFMGLCYI
                     EKCHTYTLQEFKAAQVIRLAEVTERLGEFRNEAKYVVRRACRFALRAAGFVPDDCAFG
                     PFEDYHKVQSSGSFINTPHELPTYGDSEKMTYTEQASKRHYCMRLTCFIRLNDYLIEN
                     TMHILTVNAVNSLLNHLTDKLKRTPSADVIQKWITEEKPEVPDKKGTLMVEKQEEDES
                     LIPMFLTELMLTVQSLLFEPSLEDFLDGILGAVNHCQNTVLSVPNLVPDSYFDAFTSP
                     YINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARIYAATFEKFQIF
                     FKENESLDLQALKLQEPDINFFSEQLEKYHKQHKDAVALRPTRNVGLLLIDTRLLREK
                     LIPSPLRCLEVLNFMLPRQSKKKVDAIIFEAQDAEYKLEFVPTTTTEYVHSLLFLDEI
                     QERIESLEDEGNIVTQMYKLMEQYQVPTPPEDFAVFATMKPSIVAVRNAIDKSVGDRE
                     SSIKQFCVHLGSDLEELNNEVNEVKLQAQDPQILDISADQDKIRLILNNLQSVLADLQ
                     KRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQEWLKSKFDCL
                     DPEVLNGQVSKYAKFVTQLEKGLPPNSVVPQLKYKVEKMKEKLPVIIDLRNPTLKARH
                     WAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEAALEAILKKVED
                     SWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGPLKTRVDEWQ
                     KQLALFNQTLEEWLTCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKVN
                     RLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEIL
                     AQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAMLSPEG
                     ERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPSQV
                     ILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNIL
                     TALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGY
                     EYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCV
                     VFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKL
                     SRFMFEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVIL
                     YSEGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNE
                     DVVLIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNL
                     QPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQ
                     AVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPVD
                     ALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDP
                     EELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISK
                     VTTLCCLLESLILGKDGVNLAMEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDTF
                     IRTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTD
                     TVRYGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSS
                     ARTQEIIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFG
                     GFYDRNKLFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQ
                     AILNGFLSDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQG
                     ILQCDPGTIREEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGIAIDL
                     EYFLNKPIIFGDFIKFGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFF
                     QDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYD
                     SFHEDLRKLYKMAGVEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQ
                     VLAATRPRAKEVGISEGNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLV
                     NCCTIDWFVQWPREALLSVSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYN
                     ELRRRYYTTPTSYLELINLYLSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLD
                     LSALEPVLLAKSEDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQ
                     RDLDEALPALDAANKALDSLDKADISEIRVFTKPPDLVMTVMEAISILLNAKPDWPSA
                     KQLLGDSNFLKRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVR
                     AMDLYSRVVKVVEPKRQKLRAAQAELDITMATLREKQALLRQVEDQIQALQDEYDKGV
                     NEKESLAKTMALTKARLVRAGKLTAALEDEQVRWEESIQKFEEEISNITGNVFIAAAC
                     VAYYGAFTAQYRQSLIECWIQDCQSLEIPIDPSFSLINILGDPYEIRQWNTDGLPRDL
                     ISTENGILVTQGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDSNFLRILENSIRL
                     GLPVLLEELKETLDPALEPILLKQIFISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNP
                     HYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPRLEEQRIKLIVRINTDKNQLKT
                     IEEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIKTRLEEAESTEQMINVAREKYR
                     PVATQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIETSVKTENLQQRLDVLLEQT
                     LLTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNFFLRGSAGLEKERPPKP
                     EAPWLPTATWFACCDLEESFPVFHGLTQNILSHPISIRLGSFETYINPQKWEGYSKMK
                     HEDKHMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEKVVFALTDFVIENLGKQFIET
                     PPVDLPTLYQDMSCNTPLVFILSTGSDPMGAFQRFARESGYSERVQSISLGQGQGPIA
                     EKMVKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIKDTFRLFLSSMPSNT
                     FPVTVLQNSVKVTNEPPKGLRANIRRAFTEMTPSFFEENILGKKWRQIIFGICFFHAI
                     IQERKKFGPLGWNICYEFNDSDRECALLNLKLYCKEGKIPWDALIYITGEITYGGRVT
                     DSWDQRCLRTILKRFFSPETLEEDYKYSESGIYFAPMADSLQEFKDYIENLPLIDDPE
                     IFGMHENANLVFQYKETSTLINTILEVQPRSSTGGEGKSNDEIVQELVASVQTRVPEK
                     LEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLETLNKAIAGFVVMS
                     EEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWLKRGQPKSYWI
                     SGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAKTVQFGQELP
                     MDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFEPQQNYKPSP
                     TLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSALLCQLSE"
     exon            320..493
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            494..756
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            757..1024
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1025..1159
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1280
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1281..1410
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1411..1579
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1580..1696
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1897
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            1898..2018
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2019..2170
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2171..2323
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2324..2575
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2576..2704
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2705..2818
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2819..2962
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            2963..3175
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            3176..3268
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            3269..3388
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            3389..3569
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            3570..3666
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            3667..3886
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            3887..4051
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            4052..4165
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            4166..4291
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            4292..4447
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            4448..4609
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            4610..4747
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            4748..4915
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            4916..5064
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            5065..5172
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            5173..5728
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            5729..5851
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            5852..6034
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            6035..6178
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            6179..6400
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            6401..6548
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            6549..6706
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            6707..6838
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            6839..7010
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            7011..7157
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            7158..7231
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            7232..7386
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            7387..7618
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            7619..7771
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            7772..7912
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            7913..8155
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            8156..8323
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            8324..8559
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            8560..8821
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            8822..8945
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            8946..9142
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            9143..9346
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            9347..9472
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            9473..9637
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            9638..9705
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            9706..9886
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            9887..10066
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            10067..10300
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            10301..10436
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            10437..10606
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            10607..10797
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            10798..10958
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            10959..11047
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            11048..11194
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            11195..11333
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            11334..11453
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            11454..11575
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            11576..11705
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            11706..11833
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            11834..12019
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            12020..12092
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            12093..12244
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            12245..12467
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     exon            12468..12752
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      12722..12727
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /note="hexamer: AATAAA"
     polyA_site      12752
                     /gene="DNAH6"
                     /gene_synonym="Dnahc6; DNHL1; HL-2; HL2"
                     /note="major polyA site"
ORIGIN      
        1 attccgcgct accgagtact ttctactccc gaccaggcat tgctctctct ggagaccctc
       61 ggcggtggtt gctgtatttt gacttggagt aaggatgact tttcgggcca cagatagtga
      121 atttgacctg acaaatattg aagagtatgc cgaaaattct gcactttcaa gactgaataa
      181 tataaaagcc aaacaaagag tgagttatgt gacatccaca gaaaatgaat ctgatacaca
      241 aatcctaacg tttaggcaca ttacaaaagc tcaggagaag acaagaaaac gacagcagcc
      301 tataaaacta gagcctttgc cagtgctaaa agtctaccaa gatcataagc agccagaata
      361 catacatgaa cagaaccgat ttcagttaat gactgcagga atcattaaac gtccagtaag
      421 catagcaaaa aaaagttttg ccacatcatc tactcagttt cttgagcatc aagatgctgt
      481 gaaaaaaatg cagattcatc ggccctatgt tgaggtgttc tctccctctc ctcctaaact
      541 gccacatact ggtattggaa aaagaggtct ctttgggact agatcttcag cttaccctaa
      601 gtacactttt cacgaccgag aagaagttgt taaagccaac attcgtgatc ccttgcaaat
      661 cattaaaata atacgtgaaa atgaacatct tggatttctt tatatgatcc ctgcagtgcc
      721 aagatcatcc attgaatatg atacatataa tctaaaagtt gtaagttatg agaacatcaa
      781 taaaaatgac tactatacta ttagccaaag ggcagtaaca cacatttata atgaagacat
      841 tgaatttatc gaaattgatc gatgggaaca ggaatatctg tatcacagag aactcactaa
      901 gattcccata ttttcactgt tccggaaatg gaaggctttt agtgtatgga ggaagaatgt
      961 ccgctccaag aaaatcactg gatgtcaaaa atctctacaa aaaaatttgt tcattgttaa
     1021 tcctcatttg cgaccagctc ttcttaaaat aaatgaattg tgttatcatt tgagttttat
     1081 gggactttgt tatattgaaa agtgtcacac ctacaccctg caggaattta aggccgcaca
     1141 agtcatacgg ctagcagagg tgacagaacg cctaggagaa tttcgaaatg aggcaaaata
     1201 tgtagtcagg agggcttgtc gatttgcttt gcgtgctgca ggatttgttc ctgatgactg
     1261 tgcatttgga ccttttgagg attatcataa agtgcagagc agtggaagtt tcattaatac
     1321 accacatgag ttgcccactt atggagactc tgagaaaatg acatatacag aacaggccag
     1381 caaaaggcat tattgcatga ggctgacgtg ctttattcgt ctaaacgact atctaattga
     1441 gaacacaatg cacatcttaa cggtaaatgc tgttaattcg cttttgaacc atctcactga
     1501 caagctaaaa cgaacacctt cagcagatgt cattcagaaa tggattactg aagagaagcc
     1561 tgaagtccct gataaaaagg ggacccttat ggtggaaaag caagaagaag atgaatctct
     1621 catccccatg tttctcacag aactaatgtt gacagtccag tcactgctct ttgagccttc
     1681 tctggaagac tttctggatg gtattttggg tgcagttaat cactgtcaaa acactgtgtt
     1741 atcagttcct aatctcgtgc ctgattcgta ttttgatgct ttcaccagcc cttatattaa
     1801 caacaaactt gaaggaaaaa cctgtggaac tgggccaagt ttagcagcag tatttgagga
     1861 tgataagaat tttcacacaa ttatttctca aataaaggaa accattcagg ccgcatttga
     1921 atcagcccgc atctatgcag ctacctttga aaagttccag atattcttca aggaaaatga
     1981 aagtcttgat ttacaagctc ttaaacttca ggaacctgat attaactttt ttagtgaaca
     2041 actggaaaaa tatcacaaac agcacaagga cgcagtagcg ctcagaccca ccagaaatgt
     2101 aggattgctg ctcattgata ctaggcttct aagagaaaaa ttaattccat cacctttgcg
     2161 atgcttagag gtgctaaatt ttatgcttcc tcgtcaaagc aagaaaaaag tggatgccat
     2221 tatctttgag gcacaagatg cagagtataa acttgagttt gttccaacta ctaccacaga
     2281 atatgttcat agcttattat ttcttgatga aattcaggaa cggattgaaa gccttgaaga
     2341 tgaggggaat atagtgactc aaatgtacaa gcttatggaa caatatcagg tgcccacacc
     2401 tcctgaagac tttgctgttt ttgcaactat gaagccatcc attgttgctg ttcggaatgc
     2461 cattgataaa tcagtgggtg atagagaatc aagcattaag caattttgtg tgcatttggg
     2521 tagtgatctt gaagaattaa acaacgaagt gaatgaagta aaactgcaag cacaggatcc
     2581 acagatttta gatatctctg ctgaccaaga caaaataagg ctcatattga ataatctgca
     2641 atctgttctg gctgatcttc agaaacgtgc atttcagtat aagtcctatc agaagaattt
     2701 taaggtagaa gtgtccaagt ttgaagcttt ggaagaagtc agtgctgaac tgaagctcaa
     2761 acaattgctc tgggattctt tctctgaatg ggataaactc caacaagaat ggttaaagtc
     2821 caaatttgat tgcctggatc cagaagtcct aaacggtcaa gtttctaaat atgctaaatt
     2881 tgtgactcaa ctggaaaaag gcttgccacc caacagtgta gtgccccagc tcaaatacaa
     2941 ggtggaaaaa atgaaagaaa agcttccagt tatcattgac ttgaggaacc cgactttgaa
     3001 ggcaagacat tgggcagcta ttgaacaaac agttgatgcc actctagtgg atgctgaaat
     3061 tccattaacc ttggagaggc tctcccagtt gcatgttttt gactttggtc aagaaatcca
     3121 ggacatatct ggacaggctt ctggagaagc tgccttagaa gcaattctta aaaaggtgga
     3181 ggactcttgg aaaacaactg aatttgtcat tctgcctcac cgtgactcca aagatgtgtt
     3241 tatactgggc ggcacagatg acatacaggt ccttcttgat gatagcacca tcaatgttgc
     3301 aactcttgcc tcatcacgtt accttggtcc actgaaaact cgagtggatg aatggcaaaa
     3361 acaacttgct ttatttaatc aaacactgga agagtggctg acctgccaga gaaactggct
     3421 ctacctagaa agtattttca atgctccaga cattcagagg caattgcctg cagaggccaa
     3481 gatgttcctt caggtggata agtcatggaa agaaatcatg agaaaggtga atcggctgcc
     3541 taatgctctt cgagccgcta ctcagccagg acttctggaa acttttcaaa acaataatgc
     3601 attacttgac caaattcaga agtgcctaga ggcatactta gaatcaaaaa gagttatctt
     3661 tccaaggttt tacttcttgt caaatgatga acttctggag attttggccc agacacgaaa
     3721 tccacaggcc gtgcagccac acttaaggaa atgcttcgac tccatttcaa agctcgaatt
     3781 tgctctcatg cctcctgccg aaggaaagat tcctggtatt gatggagaac cagaaaaggt
     3841 ttatactaat gatattttag caatgctgtc accagaggga gaaagggtta gcttggggaa
     3901 aggcctcaag gcccgaggca atgtagagga atggcttggt aaagtggaag aagccatgtt
     3961 cacatctctg cgtcgcctgt gcaaagctgc catcgctgac tatcagggga aactgaggac
     4021 agactgggtg gttgctggcc acccttctca agttatcctg actgtttctc aaattatgtg
     4081 gtgccgtgat ttgactgaat gtctggaaac agaacacagt aatcatatac aggccctgaa
     4141 gaattttgaa aaagtaaatt ttgagagatt aaatgcccta gctgcaatag ttcaaggcag
     4201 tcttcctaaa ttacacagaa acatcctaac tgcattgatt actattgatg tgcatgcaag
     4261 agatatagtc actgaacttg ttcaatccaa ggtggagaca gttgaatctt ttgactggca
     4321 gagacaactg cgctattact gggatataga cctggataat tgtgtggcta gaatggcgct
     4381 ctctcagtac acttatggct atgaatattt gggtgcatgc ccaagattgg ttattactcc
     4441 actcacagat cgctgctatc tttgcctcat gggagctttg cagcttgacc ttgggggtgc
     4501 accagctggt cctgctggca ctgggaaaac agagactacc aaagatctgg caaaagctct
     4561 tgccatccag tgtgtggtct ttaactgttc agatggtttg gactacaaga tgatggggcg
     4621 cttcttcagt ggcttggcac agtcaggggc ctggtgctgc tttgatgaat ttaatcgaat
     4681 tgacatagaa gttctgtccg tcatcgcgca gcaactcatt accattagga acgccaaagc
     4741 ggcaaagctc tctagattca tgtttgaggg gcgggaaata aagttggtga tgacttgtgc
     4801 agccttcatc acaatgaatc ctggctatgc agggagaact gaattgccag ataatttgaa
     4861 agccctgttt agaccatttg cgatgatggt tccaaattat gccttgattg cagaggtaat
     4921 tctatattct gaaggatttg aatccagtaa aatattagca agaaaaatga ctcagatgta
     4981 taagctttgc agtgagcagc tgtctcagca ggatcactac gactttggca tgagagctgt
     5041 gaagtctgtc ctggtcatgg ctggatcttt aaaaagagaa aacccagacc taaatgaaga
     5101 tgtggtgttg ataagagctt tacaagactc caatttgcca aaatttctaa cagatgatgc
     5161 tcttctgttc agtggaatca tatctgacct ttttcctgga gtccaaattc cagaacatga
     5221 ttatggtatt ttacaatcaa caattgtgga tgtcatgaat agacaaaatc ttcagcctga
     5281 gatgtgtatg gttagaaagg tgatacagtt ttatgaaact atgctagtaa ggcatggtgt
     5341 tatgttagtc gggccaacag gaggcggcaa gaccacagtt taccgaatac tagcagaaac
     5401 tttagggaat ttacaaaaac ttgggataga aaattccttt taccaagcag ttaaaacata
     5461 tgttctcaac cctaaatcaa ttaccatggg tgaattatat ggagaggtta ataacttaac
     5521 cttggaatgg aaagatggtt tgatggcact aagtgtccga gcagctgtga atgatacttc
     5581 agaagaccat aaatggatca tcagtgatgg gccagtagat gctctttgga ttgaaaacat
     5641 gaatacagtg ctggatgata acaagatgct ttgcctggct aacagtgaga ggattaaact
     5701 cacacctcaa attcacatgc tttttgaggt gcaagatctg cgggttgcct cccctgcaac
     5761 agtcagtcga tgtggaatgg tgtttgtgga tcctgaagaa ctgaaatgga tgccttatgt
     5821 taaaacttgg atgaagggta tttctaaaaa actgactgag gaaacccaag aatatatatt
     5881 gaatcttttc caacgttatg ttgatgaagg tttacatttt atcaataaaa agtgcagcca
     5941 agcaattcca caagtggaca tcagcaaagt tactacactc tgttgcttat tggagtcctt
     6001 gatacttggg aaagatggag ttaacttggc aatggaacaa acaaaattga acactatact
     6061 atgtcagact tttgtattct gttatttgtg gtctttgggt ggaaacctaa ctgaaaacta
     6121 ctatgattct tttgatacat ttattagaac acaatttgat gataatcctg atgccaggct
     6181 tcccaattct ggtgatctgt ggagcattca tatggacttt gacaccaaac ggctggatcc
     6241 ctgggaacga atcataccta ctttcaaata caaccgagat gttccatttt ttgaaatgct
     6301 tgtccccaca actgacacag tgcgctatgg gtatctaatg gaaaaactac tggcagtcaa
     6361 gcattccgtg ttgtttactg gaataactgg agtgggcaag tctgtgattg caaaaggatt
     6421 gctaaataaa attcaagaat cagctggcta tgtccctgtt tatctaaatt tttctgctca
     6481 aacttcatct gcaaggacac aagagatcat tgagtcaaaa ctggagagaa aaagaaaaaa
     6541 tattctagga gcaccgggaa acaaacgaat tgtgattttt gttgatgatt taaacatgcc
     6601 cagactggat cgctatggct ctcagcctcc gattgaatta cttcggcagt atcaagattt
     6661 tgggggattt tatgacagaa acaaactgtt ttggaaagaa atacaggatg taacaatcat
     6721 atcggcatgt gcacctccag gcggtggccg caaccctgtg actccccgct tcatcagaca
     6781 cttcagcatg ctgtgcctcc caatgccctc agagcacagt ctgaaacaga tttttcaggc
     6841 catcttaaat ggtttcctga gtgactttcc accagctgta aagcaaactg catcaagcat
     6901 tgtagaagcc tcagttgaga tttataacaa aatgagtgtt gacctcctgc caacacccgc
     6961 caagtcccat tatgtcttta acttgaggga cttatccaaa tgtgtgcaag gtatcctcca
     7021 atgtgatcca ggaacaataa gagaagaaat tcagatattt agactctttt gccatgagtg
     7081 ccaaagggtc ttccatgatc gcttgattaa taatgaagat aagcactatt tccatgttat
     7141 tctgacagaa atggccaaca aacattttgg aattgcaatt gacctggaat attttttgaa
     7201 taagcccatc atatttggag atttcattaa gtttggagca gataaagctg atcggattta
     7261 tgatgacatg cctgatatag agaaaactgc aaatgttcta caggactatc ttgatgatta
     7321 taatctcaca aatcccaaag aagtaaagtt ggtgttcttc caggatgcta tagaacatgt
     7381 ttcaaggatt gctcggatga tacgtcaaga aagaggcaat gccctgcttg ttggagtagg
     7441 aggcacagga aagcagtcac tcacgagact tgcagctcat atatgcggtt acaaatgttt
     7501 gcagattgaa ctcagccggg gatataatta tgatagtttt catgaagacc tgaggaagtt
     7561 gtacaaaatg gctggtgtag aagacaagaa tatggttttc cttttcactg acacccagat
     7621 tgtagtggag gagttcctag aagatataaa taacatcctg aactcaggtg aagtgcctaa
     7681 tttatttgaa aaggatgaac tggagcaggt tttagcggcc accagaccaa gagcaaaaga
     7741 agtaggaatt tctgagggga acagagacga ggtgtttcaa tactttatca gcaaagtgcg
     7801 tcagaagctg cacattgttc tctgcatgag cccagttggg gaggcctttc ggtcccgatg
     7861 caggatgttt ccatcccttg tgaattgctg caccattgac tggtttgtgc agtggcccag
     7921 agaagcactt ctttctgtgt caaagacatt tttctcacaa gtcgatgctg gaaatgaaga
     7981 actgaaagaa aagcttccct tgatgtgcgt gaacgttcac ttgagtgtct ccagcatggc
     8041 agagcgctat tacaatgagc tgcgcaggcg gtactacacg acacccacct cctacctgga
     8101 gcttatcaat ctttacctgt ctatgctgtc tgaaaaaagg aagcagatta tttcagcacg
     8161 agatcgggtg aagaatggtc tcaccaagct actagaaaca aacatactag tagataaaat
     8221 gaaactagat ctttcagctt tagagcctgt acttttagca aaatcagaag atgttgaagc
     8281 cctgatggaa aaattggcag tggatcaaga aagtgccgat caggtccgta acactgtgca
     8341 ggaggatgaa gcaacagcaa aagtcaaagc tgaagaaacc caagcaatag ctgatgatgc
     8401 tcaaagagat cttgacgagg cactacctgc actagatgct gccaataaag cactggattc
     8461 cttagataag gcagatatat ctgaaatcag agtttttaca aagcccccag atttggtcat
     8521 gacagtaatg gaagcaatct ccattctttt gaatgccaag cctgattggc catcagcaaa
     8581 gcaacttctt ggtgactcta actttctaaa aaggctttta gaatatgata aggagaacat
     8641 aaagcctcag atattggcaa agcttcaaaa gtatattaat aatcctgatt ttgtgcctga
     8701 aaaagtggag aaagtgtcca aagcatgtaa atctatgtgc atgtgggtaa gagctatgga
     8761 tttgtactct cgagtggtca aggtcgtcga accaaaaaga caaaagctcc gcgccgcaca
     8821 ggctgaactt gacattacca tggctaccct gagagaaaag caagcattac taagacaagt
     8881 agaagatcaa atacaggcct tacaagatga atatgacaaa ggtgtaaatg aaaaagaaag
     8941 cctggcaaag accatggccc tgacaaaagc acgtctagta cgtgctggaa agctgacagc
     9001 agcattagaa gatgagcagg ttcgatggga agaaagcata cagaagtttg aggaagaaat
     9061 atcaaatatc actgggaacg tgttcatagc agcagcttgt gtggcctact atggggcttt
     9121 cacagcccag tacaggcagt cacttataga gtgttggatc caggactgtc agtctctgga
     9181 gatcccaatc gatccttcct tcagtctcat taacattctt ggagatccct acgagatacg
     9241 gcagtggaac actgatgggc tgccccgtga cttgatatca acagaaaatg gcattttggt
     9301 tactcaaggc agaagatggc ctttgatgat tgatccccaa gatcaggcaa accgttggat
     9361 aaggaacaag gaaagcaaaa gtggtttaaa gatcattaag cttacagata gtaatttctt
     9421 acgaatactc gagaattcaa tccgacttgg tttacctgtc ttactggaag agcttaagga
     9481 aaccttggat ccagctctag aacccattct tttgaaacaa atttttatca gtggtggccg
     9541 actactcatc cgtcttggag actcagacat tgattatgac aaaaacttta ggttctatat
     9601 gacaaccaaa atgccaaatc cccactatct gcctgaggta tgcattaaag ttaccattat
     9661 caatttcact gtaacaaaat caggcctgga ggatcagttg ttaagtgatg tggtgcgact
     9721 tgaaaaaccc aggttggaag aacaaagaat taagctcatc gtgaggatca acactgataa
     9781 aaaccagttg aaaactatcg aagagaaaat cctgagaatg ctctttacct ctgaaggaaa
     9841 tattctggac aatgaagaac ttattgacac actccaggat tcaaagatca cttctggtgc
     9901 cattaaaacc aggctggaag aagcagagtc cactgagcag atgatcaatg tggctcgtga
     9961 gaagtatcgt ccagtggcca ctcaaggctc tgtaatgtac tttgtcattg caagcctctc
    10021 agaaatagat cctatgtacc agtactcatt aaaatacttt aaacagttgt tcaataccac
    10081 cattgaaact tctgtaaaga cagaaaatct acaacagcgc ctggacgtac tactagaaca
    10141 aactctccta actgcttatg tcaatgtttc aagaggactt tttgagcaac ataaactcat
    10201 ctacagcttt atgctttgtg ttgagatgat gcgtcagcaa ggaaccctat ctgatgctga
    10261 atggaatttc tttctccgag gttctgcagg attggaaaag gaacgcccac ctaagcctga
    10321 agctccctgg ctacctactg ctacatggtt cgcatgctgt gacttggaag aatcatttcc
    10381 agtttttcac ggacttaccc aaaatatatt gtcacatcct atttccatac gcttaggatc
    10441 ttttgagact tatattaacc cacagaaatg ggaaggctat tctaaaatga aacacgaaga
    10501 taaacacatg agacaggaaa aggaggcagc acaccaagat ccatggagtg caggattgag
    10561 ttctttccat aagctaattc ttattaaatg ttgtaaagaa gaaaaggtgg tttttgctct
    10621 tacagacttt gtgatagaaa atcttggaaa acagtttata gagacaccac ctgtggacct
    10681 gcctaccctg tatcaagaca tgtcatgcaa cactcccctg gtattcatcc taagcacagg
    10741 ctcagatccc atgggtgcat ttcagaggtt tgccagggaa agtggatatt cagaacgggt
    10801 gcagtcaatt tcactggggc aaggacaagg acctattgct gaaaaaatgg tcaaggatgc
    10861 aatgaaatca ggaaactggg tatttttgca aaattgccat cttgctgttt cttggatgtt
    10921 ggcaatggaa gagctcatta aaaccttcac agatccagat agtgctatca aggacacttt
    10981 tcgacttttt ttaagctcca tgcctagtaa tacatttcct gttacagttc ttcaaaattc
    11041 tgtcaaggtg accaatgagc ctccaaaagg cttacgtgca aatatcagac gagcatttac
    11101 tgaaatgaca ccttcgtttt ttgaagaaaa tatacttgga aaaaaatgga gacaaataat
    11161 atttggcatt tgtttcttcc atgcaattat tcaggagaga aagaagtttg gcccccttgg
    11221 ttggaatatc tgctatgaat ttaatgacag tgacagggaa tgtgctttac tgaatctcaa
    11281 actctattgt aaagaaggaa agattccctg ggatgcacta atttacatta ctggtgaaat
    11341 tacttatggt ggtagagtca cagacagctg ggaccaaaga tgccttcgta ctatcttgaa
    11401 aagatttttt tctcctgaaa cattagaaga agattataaa tactctgaat caggcatcta
    11461 ttttgcaccc atggctgaca gcctacaaga gtttaaggac tacattgaaa atctgccttt
    11521 gatcgatgac ccagaaattt ttggaatgca tgaaaatgct aatctagtct tccagtacaa
    11581 agagaccagc actttaatca acaccatact tgaggttcag ccaaggtcat ctactggtgg
    11641 agagggaaaa agcaatgacg aaattgttca agaacttgtt gcttctgtcc agaccagagt
    11701 tccagaaaaa ctggaaatgg agggtgcttc tgagagcctt tttgtcaagg atcttcaagg
    11761 acgtctgaac tccttgacca ccgttcttgg acaggaagtg gaccggttta acaacctgct
    11821 gaagttaatt catacttctc tggaaacact caacaaagcc atcgctggat ttgtggtgat
    11881 gtctgaagaa atggaaaaag tgtataacag tttcctcaac aaccaggttc ccgctctgtg
    11941 gtccaacaca gcctacccat ccctgaagcc actaggatca tgggtcaaag accttatcct
    12001 gaggacctca tttgtggatc tgtggctcaa aagaggacag cctaagtcct actggatctc
    12061 tggtttcttc tttcctcaag gatttctaac aggaactctt caaaatcatg ctcgaaaata
    12121 caatttgcct atagatgagc tgagtttcaa atacagcgta attcccacct atcgggatca
    12181 agctgcagtg atagaagctg ccaagacagt gcaatttgga caagaactgc ccatggacat
    12241 ggagttgccc tctcctgagg atggtgttct tgttcatggg atgttcatgg atgcttctcg
    12301 atgggatgat aaggagatgg tgatagaaga tgcattgccc ggacagatga atccagtgct
    12361 gcctgtggtg cattttgaac cacaacaaaa ctataagcca agcccaacac tttaccactg
    12421 cccactttat aaaacaggag cccgggcagg aacactctca accacaggac attcaaccaa
    12481 ttttgtggta accgtcctgt taccctccaa gcggtccaaa gactactgga ttgccaaggg
    12541 atcagctttg ctctgccagc tgagcgaatg aaaaggtgcc acctcagccc tgaaaaagaa
    12601 ccaggccaga gatctttcct aatgggagca aaaggtttga ataatttata tgtgagcaaa
    12661 acggtgttaa ttctgatttg acttaaacgt attgtgactt ttatttctct tatgacctta
    12721 aaataaagtg tttgagttct ttctgttggc aa
//
