LOCUS       NM_001369              15781 bp    mRNA    linear   PRI 12-OCT-2024
DEFINITION  Homo sapiens dynein axonemal heavy chain 5 (DNAH5), mRNA.
ACCESSION   NM_001369
VERSION     NM_001369.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 15781)
  AUTHORS   Song,Z., Song,X., Li,H., Cheng,Z., Mo,Z. and Yang,X.
  TITLE     Identification and validation of a prognostic-related mutant gene
            DNAH5 for hepatocellular carcinoma
  JOURNAL   Front Immunol 14, 1236995 (2023)
   PUBMED   38022557
  REMARK    GeneRIF: Identification and validation of a prognostic-related
            mutant gene DNAH5 for hepatocellular carcinoma.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15781)
  AUTHORS   Xu,Y., Feng,G., Yano,T., Masuda,S., Nagao,M., Gotoh,S., Ikejiri,M.,
            Tanabe,M. and Takeuchi,K.
  TITLE     Characteristic genetic spectrum of primary ciliary dyskinesia in
            Japanese patients and global ethnic heterogeneity: population-based
            genomic variation database analysis
  JOURNAL   J Hum Genet 68 (7), 455-461 (2023)
   PUBMED   36864285
  REMARK    GeneRIF: Characteristic genetic spectrum of primary ciliary
            dyskinesia in Japanese patients and global ethnic heterogeneity:
            population-based genomic variation database analysis.
REFERENCE   3  (bases 1 to 15781)
  AUTHORS   Kamel,A., Saberiyan,M., Adelian,S. and Teimori,H.
  TITLE     DNAH5 gene and its correlation with linc02220 expression and sperm
            characteristics
  JOURNAL   Mol Biol Rep 49 (10), 9365-9372 (2022)
   PUBMED   35960414
  REMARK    GeneRIF: DNAH5 gene and its correlation with linc02220 expression
            and sperm characteristics.
REFERENCE   4  (bases 1 to 15781)
  AUTHORS   Joo,J., Mak,A.C.Y., Xiao,S., Sleiman,P.M., Hu,D., Huntsman,S.,
            Eng,C., Kan,M., Diwakar,A.R., Lasky-Su,J.A., Weiss,S.T.,
            Sordillo,J.E., Wu,A.C., Cloutier,M., Canino,G., Forno,E.,
            Celedon,J.C., Seibold,M.A., Hakonarson,H., Williams,L.K.,
            Burchard,E.G. and Himes,B.E.
  TITLE     Genome-wide association study in minority children with asthma
            implicates DNAH5 in bronchodilator responsiveness
  JOURNAL   Sci Rep 12 (1), 12514 (2022)
   PUBMED   35869121
  REMARK    GeneRIF: Genome-wide association study in minority children with
            asthma implicates DNAH5 in bronchodilator responsiveness.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 15781)
  AUTHORS   Cheng,X.D., Ni,F. and Lu,Y.
  TITLE     Novel homozygous mutations of DNAH5 in Kartagener syndrome
  JOURNAL   QJM 115 (5), 319-320 (2022)
   PUBMED   34962988
  REMARK    GeneRIF: Novel homozygous mutations of DNAH5 in Kartagener
            syndrome.
REFERENCE   6  (bases 1 to 15781)
  AUTHORS   Omran,H., Haffner,K., Volkel,A., Kuehr,J., Ketelsen,U.P.,
            Ross,U.H., Konietzko,N., Wienker,T., Brandis,M. and Hildebrandt,F.
  TITLE     Homozygosity mapping of a gene locus for primary ciliary dyskinesia
            on chromosome 5p and identification of the heavy dynein chain DNAH5
            as a candidate gene
  JOURNAL   Am J Respir Cell Mol Biol 23 (5), 696-702 (2000)
   PUBMED   11062149
REFERENCE   7  (bases 1 to 15781)
  AUTHORS   Chapelin,C., Duriez,B., Magnino,F., Goossens,M., Escudier,E. and
            Amselem,S.
  TITLE     Isolation of several human axonemal dynein heavy chain genes:
            genomic structure of the catalytic site, phylogenetic analysis and
            chromosomal assignment
  JOURNAL   FEBS Lett 412 (2), 325-330 (1997)
   PUBMED   9256245
REFERENCE   8  (bases 1 to 15781)
  AUTHORS   Vaughan,K.T., Mikami,A., Paschal,B.M., Holzbaur,E.L., Hughes,S.M.,
            Echeverri,C.J., Moore,K.J., Gilbert,D.J., Copeland,N.G.,
            Jenkins,N.A. and Vallee,R.B.
  TITLE     Multiple mouse chromosomal loci for dynein-based motility
  JOURNAL   Genomics 36 (1), 29-38 (1996)
   PUBMED   8812413
REFERENCE   9  (bases 1 to 15781)
  AUTHORS   Zariwala,M.A., Knowles,M.R. and Leigh,M.W.
  TITLE     Primary Ciliary Dyskinesia
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301301
REFERENCE   10 (bases 1 to 15781)
  AUTHORS   Jouannet,P., Escaller,D., Serres,C. and David,G.
  TITLE     Motility of human sperm without outer dynein arms
  JOURNAL   J Submicrosc Cytol 15 (1), 67-71 (1983)
   PUBMED   6221120
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC016576.8, AC026811.5 and
            AC016546.6.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jun 15, 2020 this sequence version replaced NM_001369.2.
            
            Summary: This gene encodes a dynein protein, which is part of a
            microtubule-associated motor protein complex consisting of heavy,
            light, and intermediate chains. This protein is an axonemal heavy
            chain dynein. It functions as a force-generating protein with
            ATPase activity, whereby the release of ADP is thought to produce
            the force-producing power stroke. Mutations in this gene cause
            primary ciliary dyskinesia type 3, as well as Kartagener syndrome,
            which are both diseases due to ciliary defects. [provided by
            RefSeq, Oct 2009].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY045575.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000265104.5/ ENSP00000265104.4
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-307               AC016576.8         151686-151992       c
            308-442             AC016576.8         138414-138548       c
            443-527             AC016576.8         135398-135482       c
            528-688             AC016576.8         130584-130744       c
            689-910             AC016576.8         129411-129632       c
            911-1048            AC016576.8         127784-127921       c
            1049-1225           AC016576.8         126480-126656       c
            1226-1339           AC016576.8         124447-124560       c
            1340-1447           AC016576.8         123652-123759       c
            1448-1570           AC016576.8         121824-121946       c
            1571-1786           AC016576.8         121047-121262       c
            1787-1894           AC016576.8         118690-118797       c
            1895-1980           AC016576.8         109357-109442       c
            1981-2302           AC016576.8         108556-108877       c
            2303-2509           AC016576.8         107510-107716       c
            2510-2681           AC016576.8         101954-102125       c
            2682-2827           AC016576.8         98280-98425         c
            2828-2993           AC016576.8         93268-93433         c
            2994-3233           AC016576.8         92293-92532         c
            3234-3424           AC016576.8         90208-90398         c
            3425-3512           AC016576.8         90032-90119         c
            3513-3646           AC016576.8         83988-84121         c
            3647-3848           AC016576.8         78868-79069         c
            3849-4084           AC016576.8         78071-78306         c
            4085-4303           AC016576.8         75078-75296         c
            4304-4366           AC016576.8         73524-73586         c
            4367-4605           AC016576.8         72972-73210         c
            4606-4846           AC016576.8         71701-71941         c
            4847-5046           AC016576.8         69852-70051         c
            5047-5200           AC016576.8         66756-66909         c
            5201-5364           AC016576.8         57956-58119         c
            5365-5521           AC016576.8         52141-52297         c
            5522-5734           AC016576.8         48996-49208         c
            5735-5959           AC016576.8         48210-48434         c
            5960-6132           AC016576.8         46660-46832         c
            6133-6311           AC016576.8         37901-38079         c
            6312-6499           AC016576.8         37330-37517         c
            6500-6694           AC016576.8         36814-37008         c
            6695-6829           AC016576.8         31503-31637         c
            6830-6937           AC016576.8         30567-30674         c
            6938-7091           AC016576.8         27650-27803         c
            7092-7238           AC016576.8         24852-24998         c
            7239-7480           AC016576.8         21909-22150         c
            7481-7657           AC016576.8         18951-19127         c
            7658-7859           AC016576.8         17363-17564         c
            7860-8002           AC016576.8         16348-16490         c
            8003-8137           AC016576.8         14895-15029         c
            8138-8260           AC026811.5         82666-82788         c
            8261-8474           AC026811.5         82245-82458         c
            8475-8698           AC026811.5         80724-80947         c
            8699-8897           AC026811.5         77446-77644         c
            8898-9070           AC026811.5         74909-75081         c
            9071-9201           AC026811.5         69559-69689         c
            9202-9355           AC026811.5         65932-66085         c
            9356-9623           AC026811.5         65169-65436         c
            9624-9855           AC026811.5         59479-59710         c
            9856-9970           AC026811.5         58231-58345         c
            9971-10147          AC026811.5         57690-57866         c
            10148-10351         AC026811.5         54706-54909         c
            10352-10531         AC026811.5         51452-51631         c
            10532-10669         AC026811.5         47576-47713         c
            10670-10805         AC026811.5         42933-43068         c
            10806-11122         AC026811.5         41963-42279         c
            11123-11278         AC026811.5         40864-41019         c
            11279-11461         AC026811.5         39808-39990         c
            11462-11705         AC026811.5         25982-26225         c
            11706-11820         AC026811.5         24548-24662         c
            11821-12011         AC026811.5         23861-24051         c
            12012-12133         AC026811.5         18169-18290         c
            12134-12283         AC026811.5         16237-16386         c
            12284-12529         AC016546.6         105805-106050       c
            12530-12749         AC016546.6         103687-103906       c
            12750-12955         AC016546.6         102120-102325       c
            12956-13159         AC016546.6         101292-101495       c
            13160-13375         AC016546.6         99210-99425         c
            13376-13588         AC016546.6         92928-93140         c
            13589-13741         AC016546.6         86089-86241         c
            13742-13973         AC016546.6         85445-85676         c
            13974-15781         AC016546.6         75133-76940         c
FEATURES             Location/Qualifiers
     source          1..15781
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5p15.2"
     gene            1..15781
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /note="dynein axonemal heavy chain 5"
                     /db_xref="GeneID:1767"
                     /db_xref="HGNC:HGNC:2950"
                     /db_xref="MIM:603335"
     exon            1..307
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     CDS             251..14125
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /note="dynein, axonemal, heavy polypeptide 5; dynein heavy
                     chain 5, axonemal; ciliary dynein heavy chain 5; axonemal
                     beta dynein heavy chain 5"
                     /codon_start=1
                     /product="dynein axonemal heavy chain 5"
                     /protein_id="NP_001360.1"
                     /db_xref="CCDS:CCDS3882.1"
                     /db_xref="GeneID:1767"
                     /db_xref="HGNC:HGNC:2950"
                     /db_xref="MIM:603335"
                     /translation="MFRIGRRQLWKHSVTRVLTQRLKGEKEAKRALLDARHNYLFAIV
                     ASCLDLNKTEVEDAILEGNQIERIDQLFAVGGLRHLMFYYQDVEEAETGQLGSLGGVN
                     LVSGKIKKPKVFVTEGNDVALTGVCVFFIRTDPSKAITPDNIHQEVSFNMLDAADGGL
                     LNSVRRLLSDIFIPALRATSHGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLK
                     EKVNLRKCDILELKTLKEPTDYLTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLK
                     EADDVGPRAELEHWKKRLSKFNYLLEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRI
                     TDATNEAKDNVKYLYTLEKCCDPLYSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEK
                     ITSLFVKVTNQIISACKAYITNNGTASIWNQPQDVVEEKILSAIKLKQEYQLCFHKTK
                     QKLKQNPNAKQFDFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEGLEDMA
                     TKYQGIVATIKKKEYNFLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTN
                     QALRMLKKFERLNIPNLGIDDKYQLILENYGADIDMISKLYTKQKYDPPLARNQPPIA
                     GKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWL
                     RQIEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETECMAQMGLEVSPLATSLFQ
                     KRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLN
                     IEAYLENTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPLCQLPQEEPLTCEEFLQ
                     MTKDLCVNGAQILHFKSSLVEEAVNELVNMLLDVEVLSEEESEKISNENSVNYKNESS
                     AKREEGNFDTLTSSINARANALLLTTVTRKKKETEMLGEEARELLSHFNHQNMDALLK
                     VTRNTLEAIRKRIHSSHTINFRDSNSASNMKQNSLPIFRASVTLAIPNIVMAPALEDV
                     QQTLNKAVECIISVPKGVRQWSSELLSKKKIQERKMAALQSNEDSDSDVEMGENELQD
                     TLEIASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDCFKRYNH
                     IWQKGKEEAIKTFITQSPLLSEFESQILYFQNLEQEINAEPEYVCVGSIALYTADLKF
                     ALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAALKE
                     IREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKL
                     VSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNI
                     YRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSE
                     VNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMMER
                     HWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVI
                     NEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQK
                     WVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTR
                     AHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALL
                     EILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSISSQEGETIELDKPVMAEGN
                     VEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDS
                     EEALRNAKFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLITIHVHQRDIF
                     DDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLVITPL
                     TDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLG
                     RIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMN
                     PEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLAR
                     KFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNL
                     SKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQL
                     FETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRLD
                     VATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANG
                     DRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAE
                     ILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINMLQGLIPLKEQGGEVSQAHL
                     GRLFVFALLWSAGAALELDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPDGT
                     WTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAK
                     TVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTV
                     FIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGG
                     RNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLT
                     RRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKR
                     VIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETS
                     EEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRV
                     IRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTA
                     GQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEF
                     PRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWP
                     KDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPK
                     SYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVA
                     NDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALE
                     EAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSW
                     QESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCS
                     WTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYE
                     QAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLA
                     TAFLSYSGPFNQEFRDLLLNDWRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLP
                     NDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDS
                     LSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKL
                     PNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRR
                     MKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSARE
                     EYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANII
                     EHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKAC
                     PPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYD
                     KSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTPLI
                     CLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQEVHARKLLQQTMANGGWALLQNCHL
                     GLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPPQGLRAGLK
                     RTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNAT
                     VQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFG
                     PDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTI
                     LGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLR
                     QEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISS
                     TLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDN
                     MVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIR
                     IYAENNTLRDPRFYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALLCDVK"
     exon            308..442
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            443..527
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            528..688
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            689..910
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1048
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1225
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1339
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            1340..1447
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            1448..1570
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..1786
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..1894
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            1895..1980
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2302
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            2303..2509
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            2510..2681
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            2682..2827
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            2828..2993
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            2994..3233
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            3234..3424
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            3425..3512
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            3513..3646
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            3647..3848
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            3849..4084
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            4085..4303
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            4304..4366
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            4367..4605
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            4606..4846
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            4847..5046
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            5047..5200
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            5201..5364
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            5365..5521
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            5522..5734
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            5735..5959
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            5960..6132
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            6133..6311
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            6312..6499
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            6500..6694
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            6695..6829
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            6830..6937
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            6938..7091
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            7092..7238
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            7239..7480
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            7481..7657
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            7658..7859
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            7860..8002
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            8003..8137
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            8138..8260
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            8261..8474
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            8475..8698
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            8699..8897
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            8898..9070
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            9071..9201
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            9202..9355
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            9356..9623
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            9624..9855
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            9856..9970
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            9971..10147
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            10148..10351
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            10352..10531
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            10532..10669
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            10670..10805
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            10806..11122
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            11123..11278
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            11279..11461
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            11462..11705
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            11706..11820
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            11821..12011
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            12012..12133
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            12134..12283
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            12284..12529
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            12530..12749
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            12750..12955
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            12956..13159
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            13160..13375
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            13376..13588
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            13589..13741
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            13742..13973
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     exon            13974..15781
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /inference="alignment:Splign:2.1.0"
     regulatory      15762..15767
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /note="hexamer: AATAAA"
     polyA_site      15781
                     /gene="DNAH5"
                     /gene_synonym="CILD3; DNAHC5; HL1; KTGNR; PCD"
                     /note="major polyA site"
ORIGIN      
        1 aacaacacca ggcttcgaga gagaggagag gcccagggca gacactctag gagaaaaact
       61 tgagtggtat aagtggagtt ttaattttta ttctgtgaat gtagtgaata atacatgcaa
      121 attagaaacg tgaaagtaaa atggaagtaa aactttccat ttggaagcct gttggatgtt
      181 gagcaggtct gccaggagtt agaagaccat tccggaagag ctgactccag cctgtccatg
      241 cacggctaca atgtttagga ttgggaggag acagctctgg aagcatagcg tcactcgagt
      301 tttaacgcaa agactgaagg gagagaagga agccaagcgg gctcttttgg atgcgaggca
      361 taactactta tttgcaattg tggcttcctg tttggacctg aacaaaaccg aagtggagga
      421 tgccattctt gaagggaatc agattgaaag aattgatcaa ctttttgctg ttggaggtct
      481 ccgacacctc atgttttact atcaagatgt ggaggaagca gaaacaggac aacttggctc
      541 tctaggaggg gtaaatcttg tttctggaaa gattaaaaaa cctaaggtgt tcgtgaccga
      601 gggaaacgat gtggctctta ctggggtatg tgtgttcttc atcaggactg acccttccaa
      661 agccatcacc cctgacaaca tccaccagga ggtgagtttt aacatgttag atgcggcaga
      721 tggaggcctg ctcaacagtg tgagacgttt gctgtcggac atcttcattc ctgctctcag
      781 agccacgagc catggctggg gcgagctcga gggccttcag gacgcagcta acattcgcca
      841 ggagttcttg agctccctgg aaggctttgt gaacgtcctg tcgggtgcac aggagagtct
      901 gaaggagaag gtgaaccttc gaaagtgtga catacttgaa ctgaaaaccc taaaggaacc
      961 tacggactac ttgactctag caaataaccc tgagactttg ggaaaaatag aggattgcat
     1021 gaaagtatgg atcaaacaga cagaacaggt tcttgctgaa aacaatcagc tgctgaagga
     1081 agcggatgac gttgggccac gagcggagct ggagcactgg aaaaaaagac tctccaagtt
     1141 taactacctt ttggaacaat tgaaaagccc ggatgtgaag gctgtgctgg cagtgcttgc
     1201 ggcggccaag tcgaaactgc tgaagacttg gcgggagatg gatattcgaa tcactgatgc
     1261 aactaatgaa gcaaaggaca atgtgaaata cttgtataca cttgaaaaat gttgtgaccc
     1321 tttgtacagc agtgatcccc tatccatgat ggatgctatt cctacactta taaatgcaat
     1381 taaaatgatc tatagtatct ctcattacta taatacctct gagaagatca catctctgtt
     1441 tgtaaaggtg acaaatcaga ttatatctgc atgtaaagcc tatattacca ataatggaac
     1501 cgcttccatc tggaaccagc cacaggatgt tgttgaagaa aaaatactat ctgcgattaa
     1561 actgaaacag gaataccagc tctgctttca caagacaaaa caaaagctta aacaaaatcc
     1621 aaatgcaaaa caatttgatt ttagcgagat gtatattttt ggaaaattcg aaacttttca
     1681 ccgacgcctt gccaagataa tagacatctt tacaaccctc aagacgtatt cagtcctgca
     1741 agattccaca attgaagggc tggaagacat ggccactaaa taccagggca ttgtggcaac
     1801 cataaagaaa aaggaataca atttcctaga ccagcggaaa atggattttg accaagatta
     1861 cgaagagttt tgcaagcaga ctaatgacct tcataacgag ttgcggaagt tcatggatgt
     1921 tacatttgca aagattcaaa acacaaatca agctctaaga atgttgaaga aatttgaaag
     1981 attgaatata cctaatcttg gtattgatga caaatatcaa cttatccttg agaactatgg
     2041 ggctgacatt gatatgattt caaagctgta tacaaagcag aaatacgatc ctcctctggc
     2101 tcgaaaccag cctcccatcg ctggaaagat tttgtgggcc cgccagctct tccataggat
     2161 tcagcagccc atgcagcttt tccagcagca cccagctgtg ctaagcacgg cagaagccaa
     2221 acctataatt cgcagttaca acaggatggc caaggtcctc ctggagtttg aggtcctctt
     2281 ccacagggcg tggcttcggc aaattgaaga aattcatgta ggtcttgagg cttcattatt
     2341 ggtgaaggct ccaggcacag gggaattgtt tgtaaacttt gaccctcaga tattaatctt
     2401 atttagagaa acagagtgca tggcccagat gggtctggaa gtctctccac tggcaacttc
     2461 cctcttccag aaacgagata gatacaaaag gaacttcagt aacatgaaga tgatgctagc
     2521 tgaatatcag agagtgaagt caaaaatacc tgctgccatt gagcaattga ttgtccctca
     2581 cttggccaaa gtggatgaag ctctccaacc tggcttggct gcactgacct ggacatcact
     2641 gaatattgag gcttatttag aaaacacttt tgcaaagatc aaggacctgg agttgctgct
     2701 tgacagggtc aatgatttga ttgagttccg cattgatgcc attctagaag aaatgagcag
     2761 cacgcctctt tgtcagcttc cccaggagga gccactaacc tgtgaagagt ttctccaaat
     2821 gacaaaggat ctttgtgtaa atggtgcaca aatactacat tttaaaagct cattagtgga
     2881 ggaggcagtc aatgagcttg taaatatgtt gctggatgtg gaagttttat ctgaagaaga
     2941 aagtgaaaaa atatccaatg agaatagtgt taattacaaa aatgaaagtt cagcaaaaag
     3001 agaagaagga aattttgaca ccttgacatc atctattaat gccagggcca atgccctgct
     3061 tttgacgaca gtcacgagga aaaagaaaga aactgagatg ttaggggaag aagcccgcga
     3121 gttactctct catttcaacc atcagaacat ggatgctctt ctgaaagtta caaggaatac
     3181 actagaggcc attcgcaaac gtattcattc ctctcacaca attaacttcc gggacagtaa
     3241 cagtgcctct aacatgaagc agaacagttt gcccattttc cgggcaagcg tcactctggc
     3301 cattcccaac atcgtcatgg cccctgccct ggaagatgta cagcagaccc tgaacaaagc
     3361 cgtggagtgc atcatcagtg tccctaaggg ggtcagacag tggagcagtg aactgttgtc
     3421 caagaaaaag atacaagaaa gaaaaatggc tgctttgcag agtaatgaag acagtgattc
     3481 tgatgttgaa atgggagaaa atgaacttca agataccttg gagatagcat ctgtaaattt
     3541 acccattccc gtgcaaacca agaactatta taagaatgtt tctgaaaaca aagagattgt
     3601 aaaattagtt tctgtgctta gcacaattat caactccacc aaaaaggaag ttattacatc
     3661 catggattgc ttcaaacgct acaatcacat ttggcaaaag ggaaaagaag aagccattaa
     3721 gacatttatt acacagagcc ccttgctttc tgaatttgag tcccagattc tctatttcca
     3781 aaacctagag caggaaatta atgctgagcc tgaatatgtc tgtgtgggtt ccattgctct
     3841 gtacacagct gacttgaagt tcgccctgac tgctgagaca aaggcctgga tggttgtcat
     3901 tggacgccac tgtaacaaaa aataccggag tgagatggaa aacattttta tgcttattga
     3961 agaattcaat aagaaactaa atcgtccaat taaggaccta gatgatattc ggattgcaat
     4021 ggcagcgctg aaagaaataa gggaggagca aatctccatt gactttcaag taggacctat
     4081 tgaggaatct tatgccctgc ttaacagata tggacttctg atagcaaggg aagagataga
     4141 caaagttgat acactgcact atgcttggga gaagctgctg gcacgtgctg gcgaagtcca
     4201 gaataaatta gtctcactgc agcccagttt caagaaagag cttattagtg ctgtggaggt
     4261 attcctccaa gattgtcacc agttttatct ggactatgat ttgaatggtc caatggctag
     4321 cggcttgaag ccccaggaag ccagtgacag gcttatcatg tttcagaatc aatttgataa
     4381 tatctatcgg aaatacatca catatactgg aggagaggag ctttttggcc tgccagctac
     4441 acagtatcct cagcttcttg aaataaagaa gcaactaaat cttctacaga aaatatatac
     4501 tctgtacaac agtgtcatag aaactgtaaa tagctattat gatattcttt ggtcagaggt
     4561 gaatattgaa aaaattaaca atgaactctt agaattccag aacagatgtc gaaagcttcc
     4621 ccgggccttg aaggactggc aggctttttt ggacctgaag aagatcattg atgatttcag
     4681 cgagtgttgc ccgctgctgg aatacatggc cagtaaagcc atgatggagc ggcactggga
     4741 aaggataacc accctcaccg ggcacagtct ggatgtgggg aatgaaagct ttaagttaag
     4801 aaatatcatg gaggcacctc ttctgaaata taaagaggaa atagaggaca tctgtatcag
     4861 tgcggtgaaa gagagagaca ttgagcaaaa gctgaagcaa gtgattaatg aatgggacaa
     4921 taaaacattc accttcggca gctttaaaac ccgtggagag ctcctcttga gaggagacag
     4981 tacctcggaa atcatcgcca acatggagga cagcttgatg ttgctgggat ccctactgag
     5041 caacaggtac aatatgccat tcaaagccca gattcaaaaa tgggtgcagt acctttccaa
     5101 ctcaacagac atcatcgaga gctggatgac ggtgcaaaac ctgtggattt atttagaagc
     5161 tgtctttgtg ggaggagaca ttgccaagca gctgcccaag gaagccaagc ggttttctaa
     5221 catagataaa tcttgggtga agatcatgac tcgggcacat gaagtgccca gtgtagtcca
     5281 gtgctgtgtt ggagatgaga ccctggggca gctgttacca cacttgctgg accagttgga
     5341 aatatgccag aaatccctta ctgggtactt ggagaaaaaa cgactgtgct ttcctcggtt
     5401 tttcttcgtc tcagatcctg cccttctaga gattctgggg caggcgtcgg actcccacac
     5461 tatacaggcc catttgctga atgtgtttga caacattaaa tctgtcaagt tccacgaaaa
     5521 gatctatgat cgaattctgt caatttcctc tcaagagggt gagacgattg aattggataa
     5581 acctgtcatg gcagagggca atgtggaagt ttggcttaat tctcttttgg aagaatctca
     5641 gtcctcattg catcttgtga ttcgccaggc agccgcaaat attcaagaaa caggtttcca
     5701 actaactgaa tttctttcat ccttccctgc tcaggttgga ttattaggaa ttcagatgat
     5761 atggacacgg gattcagaag aagcccttag aaatgccaag tttgataaaa aaatcatgca
     5821 gaaaactaat caggctttcc tggagctact caatacattg atagacgtca ccacgaggga
     5881 tctgagttcc acggaacgag tgaaatacga gactctgatt actattcatg tgcaccaaag
     5941 ggatatcttt gatgacctgt gtcatatgca tatcaagagt cccatggact ttgagtggct
     6001 gaaacagtgc agattttact ttaacgaaga ttctgacaag atgatgattc acatcacaga
     6061 tgtggcgttc atataccaga atgaattttt aggctgcact gacaggcttg taataactcc
     6121 acttacagac agatgttaca tcacgctggc tcaagctctg ggaatgagca tggggggagc
     6181 ccctgctgga cctgcaggca caggcaaaac agaaaccact aaagacatgg gacgatgcct
     6241 cgggaaatac gtcgtggttt tcaattgttc agaccagatg gatttccgag gacttggacg
     6301 gatttttaag ggactggcac agtctggatc ctggggttgt tttgatgaat ttaaccgtat
     6361 tgatctacca gttctctcgg ttgcagccca gcaaatttcc attattctga catgtaaaaa
     6421 ggagcacaaa aagtctttta tctttactga tggagataat gtgactatga accctgaatt
     6481 tgggcttttc ttaaccatga atcctggcta tgccggacgg caggaactcc ctgaaaactt
     6541 gaagattaat ttccgctcag tggccatgat ggtgcctgac cgtcagatta tcataagggt
     6601 gaagttggct agttgtggct tcattgacaa cgttgttttg gccaggaagt ttttcacgct
     6661 ctacaaactg tgtgaggagc agctttctaa gcaggttcat tatgactttg gcctgcgtaa
     6721 cattctgtca gttcttcgga ccttgggagc agcaaaaaga gccaatccaa tggatacgga
     6781 gtccacgatt gtcatgcgtg tactacggga catgaatctt tctaaactga ttgatgagga
     6841 tgaacccttg tttttgagtt tgattgaaga tctctttcca aatattcttc tggacaaggc
     6901 aggttaccct gaactggaag cagcaattag tagacaggtt gaagaagctg gtttaatcaa
     6961 ccatcctcct tggaaactga aggtcatcca gctattcgaa acgcagagag tgcgacatgg
     7021 gatgatgact ctggggccca gtggggctgg gaagaccacc tgcatccaca ccttgatgag
     7081 agccatgaca gattgtggaa aaccacatcg ggaaatgagg atgaatccca aagcgattac
     7141 tgccccacag atgtttggtc ggctggacgt tgccacaaat gactggactg atgggatatt
     7201 ttctacgctt tggaggaaaa cattaagagc aaagaaaggg gaacatatct ggataattct
     7261 tgatggtcca gtagatgcca tctggattga aaatctgaat tctgttttgg atgataacaa
     7321 aactctaacc cttgccaatg gtgatcggat tcccatggct ccaaactgca agatcatttt
     7381 cgagcctcat aacattgaca atgcttctcc tgccaccgtc tcaagaaatg gaatggtttt
     7441 catgagctct tctatccttg attggagtcc tattcttgag ggttttctta agaaacgctc
     7501 acctcaagaa gcagaaattc ttcgtcagct gtacaccgag tctttcccag acttgtatcg
     7561 cttctgtatc cagaacttag aatacaagat ggaggtgctg gaggcctttg tcatcacaca
     7621 gagcattaac atgcttcaag gcctgattcc tctgaaggag caaggcgggg aggtgagcca
     7681 ggctcacctg gggcggctgt tcgtgttcgc gctgctgtgg agcgcggggg cggcgctgga
     7741 gctggacgga cggcgccgcc tggagctctg gctgcgctct cggcccacag ggacgctgga
     7801 gctgccgccg ccagcggggc ccggggacac cgccttcgac tactatgtgg cgcccgatgg
     7861 tacatggacg cactggaaca cgcgtaccca ggaatacctg tatccgtctg ataccacccc
     7921 agagtatggt tctattctgg tgccaaatgt tgacaatgtg aggactgact ttctaattca
     7981 aaccattgct aaacagggca aggctgtgct attaattggt gaacaaggaa cagccaaaac
     8041 agtaataatt aaaggattta tgtcaaaata tgatcctgaa tgtcacatga tcaagagtct
     8101 gaatttttct tctgcaacca ccccactgat gttccagagg acgatagaga gctatgtgga
     8161 taaacgaatg ggtacaacat atggccctcc tgcgggaaag aagatgactg tttttattga
     8221 tgatgtgaat atgccaataa tcaatgagtg gggagatcag gttacgaatg agatagtgcg
     8281 acagctgatg gaacaaaatg gattctataa tctagagaag cctggggagt tcaccagcat
     8341 cgtggacatc cagtttttgg cagccatgat ccatcctggt ggtggacgca atgacatacc
     8401 ccaaagactc aagaggcagt tctctatatt taattgcacg ttgccctctg aagcttctgt
     8461 ggacaagatc tttggtgtga ttggggtagg ccactactgt actcagaggg gtttctcaga
     8521 agaagtgaga gattctgtga caaaattggt gcctctgaca cgccgactat ggcagatgac
     8581 caagattaaa atgcttccta cccctgcaaa attccattat gtgtttaacc tacgagatct
     8641 ttctcgggtc tggcagggaa tgctgaacac tacttcagag gtcatcaagg aaccaaatga
     8701 tctgttaaag ctgtggaagc atgagtgtaa acgtgttata gctgaccgtt tcacagtgtc
     8761 cagtgatgtg acctggtttg ataaggcttt agtaagtttg gtagaggagg agtttggtga
     8821 agagaaaaaa ctcttggtgg attgtggaat tgacacatat tttgtggatt tcttgagaga
     8881 tgcacctgaa gctgcaggtg aaacatctga agaggctgat gctgaaacac ctaaaattta
     8941 tgagccaatt gaatctttta gtcacctaaa agagcgtctg aatatgttcc tgcagctcta
     9001 taatgagagc atccgtggcg ccggcatgga catggtgttc tttgcagatg ccatggttca
     9061 cttagtcaag atctctcgtg tcattcgtac tcctcaggga aatgccctcc tggtcggggt
     9121 gggcggatca ggaaagcaga gcctgacgag gttggcttca ttcattgctg gctacgtttc
     9181 cttccagatc actctgacga gatcctacaa cacatcaaat ctgatggaag atctgaaggt
     9241 tttgtatcga acagctggtc agcaaggcaa aggaatcact tttattttca cagacaatga
     9301 gattaaagat gagtcatttt tggaatatat gaacaatgtt ttatcatcag gtgaggtctc
     9361 taacctattt gctcgagatg aaattgatga aattaatagc gacctggcat cagtcatgaa
     9421 aaaagaattc cccaggtgcc ttcctaccaa tgagaacctg cacgactact tcatgagtcg
     9481 ggtccgacag aaccttcata ttgtgctctg cttctcgcca gtgggggaga aatttcgaaa
     9541 cagagctttg aagttccctg ccctaatttc aggatgcaca attgactggt tcagccgatg
     9601 gcccaaagat gctttagttg ctgtgtctga acacttcctc acttcctatg atattgactg
     9661 cagtttggaa atcaagaagg aggtggtcca atgcatgggc tccttccagg atggggtggc
     9721 tgagaagtgt gttgattatt ttcagagatt ccgacgttct acccacgtga cgcccaaatc
     9781 atacctctcc tttattcagg gctataagtt catatatgga gaaaagcatg tggaggtgcg
     9841 gaccctggcc aacagaatga atactggatt ggaaaagctc aaagaagctt cagagtctgt
     9901 tgcagccttg agtaaagaac tggaagcgaa agaaaaggag ctacaagtgg ccaacgataa
     9961 agccgacatg gtcttaaaag aagtgacaat gaaagcacag gctgctgaaa aggtcaaggc
    10021 tgaggtacag aaggtgaagg acagggccca ggccattgtg gacagcatct ctaaagacaa
    10081 agccattgct gaagaaaaac tggaagcagc aaaaccagct ttagaagagg cagaagctgc
    10141 attgcagacc atcaggcctt cggacatcgc cactgttcgc acgttgggcc gcccccctca
    10201 cctcatcatg cggatcatgg attgcgtact gctgctgttt caaaggaaag tcagtgctgt
    10261 gaaaattgac ctggaaaaaa gctgtaccat gccctcctgg caggaatcct taaaattgat
    10321 gactgcaggg aactttttac agaacttaca gcaattccca aaagacacaa tcaatgaaga
    10381 ggtgatagaa tttttgagtc cttactttga aatgcctgac tataacatcg aaactgctaa
    10441 acgcgtatgt ggaaatgtag ctggtctttg ttcctggacg aaagctatgg cttccttctt
    10501 ttctataaac aaagaagtac tgcctctgaa ggccaacttg gtggtgcaag agaatcgcca
    10561 tctcctggcc atgcaggatc tgcagaaagc ccaggccgag ttggatgaca agcaggcgga
    10621 acttgacgtg gtgcaggctg agtatgaaca ggccatgact gaaaagcaga ccttgcttga
    10681 agatgcagag cgatgcagac acaagatgca gacagcttcc acgctcatca gtggcttggc
    10741 aggtgaaaaa gaaagatgga cagagcaaag ccaagagttt gctgcacaaa ctaaaagact
    10801 tgtaggggat gtactgttgg ctacagcttt tctatcttat tctggtccat ttaaccaaga
    10861 gtttcgtgat cttctgttaa atgactggcg gaaggaaatg aaagcccgga aaattccatt
    10921 tggaaagaac ctaaatctca gtgagatgtt gattgatgct cctactatta gtgaatggaa
    10981 cctccaaggt ctgccaaatg atgacttgtc cattcaaaat ggaattattg tcacgaaggc
    11041 atctcgttac cctttgttaa ttgatccaca gactcaaggc aagatctgga ttaaaaataa
    11101 agaaagccga aatgaactcc agatcacgtc tttaaatcac aagtacttca gaaaccacct
    11161 ggaagacagc ctttctcttg gaaggccttt gcttattgaa gatgttggag aggaactaga
    11221 tccagcacta gataatgttt tggaaagaaa cttcattaaa actgggtcta cctttaaggt
    11281 gaaagttggt gacaaggaag tagatgtgtt ggatggcttt agactctaca ttaccaccaa
    11341 attgcctaac ccagcctaca cccctgagat aagtgcccgt acctccatca ttgacttcac
    11401 tgtcaccatg aaaggtctag aagatcagtt actggggagg gtcattctca cagagaagca
    11461 ggaattggag aaagaaagaa ctcatctgat ggaagatgta actgcaaaca aaagaaggat
    11521 gaaggaacta gaagataact tgctttaccg cctgacaagt acccaggggt ccctggtaga
    11581 agatgaaagt ctcattgtcg tgctgagtaa cacaaaaagg acagccgagg aggtgacaca
    11641 gaagctagaa atttctgctg agacagaagt tcaaattaac tcagcccggg aggaatacag
    11701 acctgtggct acgcggggca gcatcctcta cttcctcatt actgagatgc gcttggttaa
    11761 tgagatgtat cagacttcgc ttcgccagtt tctgggctta tttgaccttt ccttagccag
    11821 gtctgtcaag agcccgatta caagcaagag gattgctaat atcatcgagc acatgaccta
    11881 cgaggtttat aagtatgctg cccgagggct gtacgaggag cacaaattcc tgttcacctt
    11941 gttgcttacc ctaaagattg acatccagag gaaccgagtc aagcatgaag agtttctcac
    12001 tcttattaaa ggaggtgcct cattagacct taaagcttgt cctccaaaac catcaaaatg
    12061 gatcctggac ataacatggc tgaatttggt ggaacttagc aaactcagac agttttcaga
    12121 tgtccttgac cagatatcga gaaatgagaa aatgtggaaa atttggtttg ataaggaaaa
    12181 cccggaggag gaacctcttc caaatgccta tgataaatct cttgactgct tcagacgtct
    12241 tctccttatt agatcctggt gtcctgacag aaccatcgcc caggcccgca agtacatcgt
    12301 ggactccatg ggagaaaaat atgccgaagg tgttatttta gacttggaga agacgtggga
    12361 ggaatctgat ccacggacgc cactcatctg tctcctgtct atgggctcag accccacaga
    12421 ttccatcatt gccttgggga agagattaaa aatagaaacc cgttatgtgt ccatgggcca
    12481 gggccaggaa gtccatgctc ggaagctctt gcagcagacc atggcgaacg gaggatgggc
    12541 acttctgcag aactgccatc tgggacttga tttcatggat gagctgatgg acataatcat
    12601 agaaactgag cttgtacatg atgcgttccg cctctggatg accaccgagg ctcataagca
    12661 gtttcccatt acactccttc agatgtccat taaatttgcc aacgatcctc cacaaggact
    12721 ccgggcagga ctgaaaagaa catatagtgg tgtcagccaa gacctgctgg acgtgagctc
    12781 tgggtcccag tggaagccca tgctgtacgc agtggctttc ctgcactcca ctgtccagga
    12841 gaggcgcaag ttcggtgccc tggggtggaa tatcccctac gaatttaacc aagcggactt
    12901 taatgccact gtgcagttca tccaaaacca cttggatgac atggatgtca aaaagggtgt
    12961 ctcctggacc accatccgct acatgatagg agagattcaa tatggaggca gagtcactga
    13021 cgactatgat aagagattgt tgaacacatt tgctaaggtt tggttcagtg aaaatatgtt
    13081 tggaccagat ttcagttttt accaaggata caatattcca aaatgcagca cagtggataa
    13141 ctatcttcag tatatccaga gtttgcctgc ctatgacagc cctgaggtgt ttgggctgca
    13201 ccccaatgct gacatcacct accagagcaa gctggccaag gacgtgctgg acaccatcct
    13261 aggcatccaa cccaaggaca cctctggtgg aggggatgag acccgggagg cggtggtggc
    13321 ccggctggct gatgatatgc tggagaagct gcccccagac tatgtcccct ttgaagtaaa
    13381 agagaggctg cagaagatgg ggccattcca gcctatgaac attttcctca ggcaggaaat
    13441 agacagaatg caaagggtac tcagccttgt ccgcagcacc ctcactgagc tgaaacttgc
    13501 tattgatggc accatcatca tgagcgaaaa tctgcgagat gcattggatt gcatgtttga
    13561 tgctagaatc cctgcttggt ggaaaaaagc ttcttggatt tctagtacac tgggtttctg
    13621 gtttactgaa cttatagaaa gaaacagcca gtttacctcg tgggttttca atggccgacc
    13681 tcactgcttt tggatgacgg gtttttttaa cccccaggga tttttaactg caatgcgaca
    13741 ggaaataact cgggccaaca aaggctgggc tctggacaat atggtgcttt gcaatgaagt
    13801 caccaaatgg atgaaggacg acatttctgc ccctcccaca gagggtgtct atgtctatgg
    13861 cttatatctt gaaggtgctg gctgggacaa gaggaacatg aaactcattg aatcaaagcc
    13921 aaaagtgctc tttgagttga tgcctgtcat aaggatttat gcagaaaaca atactttacg
    13981 agatcctcgg ttttactcct gtcccatcta taagaagcca gttcgaacgg acttgaacta
    14041 cattgccgct gtggatctca ggacagccca gacccctgaa cactgggtgc tccgtggggt
    14101 tgcccttctg tgtgatgtca agtaacatgt ggggagtgtc cccacccaat gctttggaaa
    14161 atgcaagatc taaattattg taacctttat ttctgtatga ctgctggaca gtgtatgtta
    14221 ggtcgtttat gcaattaatg agctgcatag gttttcccca ctccttaatt ggatgcttat
    14281 attttacttg tttcatcatt agtgaccaat gtctgagttt gttgaaaatg ttatttagtg
    14341 atataaaagt aaatttacag catcctaatg aagtgtggcc ctcaaatcca cagtagtata
    14401 ttttcttctt acttcgctcc gaagactgac tagggtaagc agacagtatt tctctgggag
    14461 gaattattct tctgttaacg tggcctggta acagccaagt tcttgaaggt aacagggcaa
    14521 gtctgtgctg attttgcttc tattgccttt cgtatttagg tcaagttaag agacttattt
    14581 tcagggtttc aagcagccaa ttaaaaatac cttttaaaaa atagaaggaa atagaagaat
    14641 ggattaagaa tgtaaataga aaatttatgt aaacatagag aataaacgta gaacaatgct
    14701 taagcctact tataattaat aatgaaatac taattgataa ttcttataat aaaaattaaa
    14761 gctaaaagta aatgatagca tgctctcagt aaaactgatc cactcacaaa ttgctggagc
    14821 aatgtaaatc aacccaacct ttttgtaaaa tgattaaata cagaaagagc cataaaaata
    14881 ttcacaccct tggatctttg ttttctctac atcaaggaaa caatttaaaa gactgaaaac
    14941 agtctatata aaattgcatt taataacaga aaaaaatgga aaaatcataa atattcaata
    15001 gtcaggctat ggttaaggaa attaagagat atttggcaac cataaaaaac aattttgaag
    15061 attccataat atgaaatggt agacccagac tgttaagtga aagatttagt ttacaaaata
    15121 ttgagcacac tgtgattata acagcaaata tatttgcatg tggacaaaga ttagatggca
    15181 agatagaaaa ataagaacag atgtgatagc aagaattata gttggcttga aaaaatgtga
    15241 tgatcaggag aaaaaataaa aaaagggtag aaatattaga cggtgcgtag ggactttcta
    15301 tggactttta ttaattagga aacattatca aaggaacttt tcacgtattt ttctttaaat
    15361 tctggttaga tgttattaat aattcttcat ctaacctact gactagaaaa tatagtcagt
    15421 actaaattag aattgtggtt tataaacttt tggttagctc tggatctgta taactgcatt
    15481 tttttggata aacagttttt ggtaggtgga taccgggaga caagtgtggg tccctctcac
    15541 tgggcttcat tctgtggacc aggatcatta tttcatgctc atgatcatga gagttaggac
    15601 tgagtggctc ctgtgactcc caccatctta gatgatactg ttttcttgtg agttctttct
    15661 tttggtgtgg attagtatat cagttgattt gtgtgaattg tggtgaaaca atcatttcat
    15721 tttgaaaagc aagtaatgaa aatgtcaaca tcataggaat taataaaatg tttttactaa
    15781 a
//
