LOCUS       NM_001372106           14039 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens dynein axonemal heavy chain 10 (DNAH10), transcript
            variant 3, mRNA.
ACCESSION   NM_001372106
VERSION     NM_001372106.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 14039)
  AUTHORS   Wang,R., Yang,D., Tu,C., Lei,C., Ding,S., Guo,T., Wang,L., Liu,Y.,
            Lu,C., Yang,B., Ouyang,S., Gong,K., Tan,Z., Deng,Y., Tan,Y.,
            Qing,J. and Luo,H.
  TITLE     Dynein axonemal heavy chain 10 deficiency causes primary ciliary
            dyskinesia in humans and mice
  JOURNAL   Front Med 17 (5), 957-971 (2023)
   PUBMED   37314648
  REMARK    GeneRIF: Dynein axonemal heavy chain 10 deficiency causes primary
            ciliary dyskinesia in humans and mice.
REFERENCE   2  (bases 1 to 14039)
  AUTHORS   Li,K., Wang,G., Lv,M., Wang,J., Gao,Y., Tang,F., Xu,C., Yang,W.,
            Yu,H., Shao,Z., Geng,H., Tan,Q., Shen,Q., Tang,D., Ni,X., Wang,T.,
            Song,B., Wu,H., Huo,R., Zhang,Z., Xu,Y., Zhou,P., Tao,F., Wei,Z.,
            He,X. and Cao,Y.
  TITLE     Bi-allelic variants in DNAH10 cause asthenoteratozoospermia and
            male infertility
  JOURNAL   J Assist Reprod Genet 39 (1), 251-259 (2022)
   PUBMED   34657236
  REMARK    GeneRIF: Bi-allelic variants in DNAH10 cause
            asthenoteratozoospermia and male infertility.
REFERENCE   3  (bases 1 to 14039)
  AUTHORS   Tu,C., Cong,J., Zhang,Q., He,X., Zheng,R., Yang,X., Gao,Y., Wu,H.,
            Lv,M., Gu,Y., Lu,S., Liu,C., Tian,S., Meng,L., Wang,W., Tan,C.,
            Nie,H., Li,D., Zhang,H., Gong,F., Hu,L., Lu,G., Xu,W., Lin,G.,
            Zhang,F., Cao,Y. and Tan,Y.Q.
  TITLE     Bi-allelic mutations of DNAH10 cause primary male infertility with
            asthenoteratozoospermia in humans and mice
  JOURNAL   Am J Hum Genet 108 (8), 1466-1477 (2021)
   PUBMED   34237282
  REMARK    GeneRIF: Bi-allelic mutations of DNAH10 cause primary male
            infertility with asthenoteratozoospermia in humans and mice.
REFERENCE   4  (bases 1 to 14039)
  AUTHORS   Li,M., Lin,A., Luo,P., Shen,W., Xiao,D., Gou,L., Zhang,J. and
            Guo,L.
  TITLE     DNAH10 mutation correlates with cisplatin sensitivity and tumor
            mutation burden in small-cell lung cancer
  JOURNAL   Aging (Albany NY) 12 (2), 1285-1303 (2020)
   PUBMED   31959735
  REMARK    GeneRIF: DNAH10 mutation correlates with cisplatin sensitivity and
            tumor mutation burden in small-cell lung cancer.
REFERENCE   5  (bases 1 to 14039)
  AUTHORS   Lagus,H., Klaas,M., Juteau,S., Elomaa,O., Kere,J., Vuola,J.,
            Jaks,V. and Kankuri,E.
  TITLE     Discovery of increased epidermal DNAH10 expression after
            regeneration of dermis in a randomized with-in person trial -
            reflections on psoriatic inflammation
  JOURNAL   Sci Rep 9 (1), 19136 (2019)
   PUBMED   31836722
  REMARK    GeneRIF: Discovery of increased epidermal DNAH10 expression after
            regeneration of dermis in a randomized with-in person trial -
            reflections on psoriatic inflammation.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 14039)
  AUTHORS   Fox,C.S., Liu,Y., White,C.C., Feitosa,M., Smith,A.V.,
            Heard-Costa,N., Lohman,K., Johnson,A.D., Foster,M.C.,
            Greenawalt,D.M., Griffin,P., Ding,J., Newman,A.B., Tylavsky,F.,
            Miljkovic,I., Kritchevsky,S.B., Launer,L., Garcia,M.,
            Eiriksdottir,G., Carr,J.J., Gudnason,V., Harris,T.B., Cupples,L.A.
            and Borecki,I.B.
  CONSRTM   GIANT Consortium; MAGIC Consortium; GLGC Consortium
  TITLE     Genome-wide association for abdominal subcutaneous and visceral
            adipose reveals a novel locus for visceral fat in women
  JOURNAL   PLoS Genet 8 (5), e1002695 (2012)
   PUBMED   22589738
REFERENCE   7  (bases 1 to 14039)
  AUTHORS   Dastani,Z., Hivert,M.F., Timpson,N., Perry,J.R., Yuan,X.,
            Scott,R.A., Henneman,P., Heid,I.M., Kizer,J.R., Lyytikainen,L.P.,
            Fuchsberger,C., Tanaka,T., Morris,A.P., Small,K., Isaacs,A.,
            Beekman,M., Coassin,S., Lohman,K., Qi,L., Kanoni,S., Pankow,J.S.,
            Uh,H.W., Wu,Y., Bidulescu,A., Rasmussen-Torvik,L.J.,
            Greenwood,C.M., Ladouceur,M., Grimsby,J., Manning,A.K., Liu,C.T.,
            Kooner,J., Mooser,V.E., Vollenweider,P., Kapur,K.A., Chambers,J.,
            Wareham,N.J., Langenberg,C., Frants,R., Willems-Vandijk,K.,
            Oostra,B.A., Willems,S.M., Lamina,C., Winkler,T.W., Psaty,B.M.,
            Tracy,R.P., Brody,J., Chen,I., Viikari,J., Kahonen,M.,
            Pramstaller,P.P., Evans,D.M., St Pourcain,B., Sattar,N., Wood,A.R.,
            Bandinelli,S., Carlson,O.D., Egan,J.M., Bohringer,S., van
            Heemst,D., Kedenko,L., Kristiansson,K., Nuotio,M.L., Loo,B.M.,
            Harris,T., Garcia,M., Kanaya,A., Haun,M., Klopp,N., Wichmann,H.E.,
            Deloukas,P., Katsareli,E., Couper,D.J., Duncan,B.B.,
            Kloppenburg,M., Adair,L.S., Borja,J.B., Wilson,J.G., Musani,S.,
            Guo,X., Johnson,T., Semple,R., Teslovich,T.M., Allison,M.A.,
            Redline,S., Buxbaum,S.G., Mohlke,K.L., Meulenbelt,I.,
            Ballantyne,C.M., Dedoussis,G.V., Hu,F.B., Liu,Y., Paulweber,B.,
            Spector,T.D., Slagboom,P.E., Ferrucci,L., Jula,A., Perola,M.,
            Raitakari,O., Florez,J.C., Salomaa,V., Eriksson,J.G.,
            Frayling,T.M., Hicks,A.A., Lehtimaki,T., Smith,G.D.,
            Siscovick,D.S., Kronenberg,F., van Duijn,C., Loos,R.J.,
            Waterworth,D.M., Meigs,J.B., Dupuis,J., Richards,J.B., Voight,B.F.,
            Scott,L.J., Steinthorsdottir,V., Dina,C., Welch,R.P., Zeggini,E.,
            Huth,C., Aulchenko,Y.S., Thorleifsson,G., McCulloch,L.J.,
            Ferreira,T., Grallert,H., Amin,N., Wu,G., Willer,C.J.,
            Raychaudhuri,S., McCarroll,S.A., Hofmann,O.M., Segre,A.V., van
            Hoek,M., Navarro,P., Ardlie,K., Balkau,B., Benediktsson,R.,
            Bennett,A.J., Blagieva,R., Boerwinkle,E., Bonnycastle,L.L.,
            Bostrom,K.B., Bravenboer,B., Bumpstead,S., Burtt,N.P.,
            Charpentier,G., Chines,P.S., Cornelis,M., Crawford,G., Doney,A.S.,
            Elliott,K.S., Elliott,A.L., Erdos,M.R., Fox,C.S., Franklin,C.S.,
            Ganser,M., Gieger,C., Grarup,N., Green,T., Griffin,S., Groves,C.J.,
            Guiducci,C., Hadjadj,S., Hassanali,N., Herder,C., Isomaa,B.,
            Jackson,A.U., Johnson,P.R., Jorgensen,T., Kao,W.H., Kong,A.,
            Kraft,P., Kuusisto,J., Lauritzen,T., Li,M., Lieverse,A.,
            Lindgren,C.M., Lyssenko,V., Marre,M., Meitinger,T., Midthjell,K.,
            Morken,M.A., Narisu,N., Nilsson,P., Owen,K.R., Payne,F.,
            Petersen,A.K., Platou,C., Proenca,C., Prokopenko,I., Rathmann,W.,
            Rayner,N.W., Robertson,N.R., Rocheleau,G., Roden,M., Sampson,M.J.,
            Saxena,R., Shields,B.M., Shrader,P., Sigurdsson,G., Sparso,T.,
            Strassburger,K., Stringham,H.M., Sun,Q., Swift,A.J., Thorand,B.,
            Tichet,J., Tuomi,T., van Dam,R.M., van Haeften,T.W., van Herpt,T.,
            van Vliet-Ostaptchouk,J.V., Walters,G.B., Weedon,M.N., Wijmenga,C.,
            Witteman,J., Bergman,R.N., Cauchi,S., Collins,F.S., Gloyn,A.L.,
            Gyllensten,U., Hansen,T., Hide,W.A., Hitman,G.A., Hofman,A.,
            Hunter,D.J., Hveem,K., Laakso,M., Morris,A.D., Palmer,C.N.,
            Rudan,I., Sijbrands,E., Stein,L.D., Tuomilehto,J., Uitterlinden,A.,
            Walker,M., Watanabe,R.M., Abecasis,G.R., Boehm,B.O., Campbell,H.,
            Daly,M.J., Hattersley,A.T., Pedersen,O., Barroso,I., Groop,L.,
            Sladek,R., Thorsteinsdottir,U., Wilson,J.F., Illig,T., Froguel,P.,
            van Duijn,C.M., Stefansson,K., Altshuler,D., Boehnke,M.,
            McCarthy,M.I., Soranzo,N., Wheeler,E., Glazer,N.L.,
            Bouatia-Naji,N., Magi,R., Randall,J., Elliott,P., Rybin,D.,
            Dehghan,A., Hottenga,J.J., Song,K., Goel,A., Lajunen,T., Doney,A.,
            Cavalcanti-Proenca,C., Kumari,M., Timpson,N.J., Zabena,C.,
            Ingelsson,E., An,P., O'Connell,J., Luan,J., Elliott,A.,
            McCarroll,S.A., Roccasecca,R.M., Pattou,F., Sethupathy,P.,
            Ariyurek,Y., Barter,P., Beilby,J.P., Ben-Shlomo,Y., Bergmann,S.,
            Bochud,M., Bonnefond,A., Borch-Johnsen,K., Bottcher,Y., Brunner,E.,
            Bumpstead,S.J., Chen,Y.D., Chines,P., Clarke,R., Coin,L.J.,
            Cooper,M.N., Crisponi,L., Day,I.N., de Geus,E.J., Delplanque,J.,
            Fedson,A.C., Fischer-Rosinsky,A., Forouhi,N.G., Franzosi,M.G.,
            Galan,P., Goodarzi,M.O., Graessler,J., Grundy,S., Gwilliam,R.,
            Hallmans,G., Hammond,N., Han,X., Hartikainen,A.L., Hayward,C.,
            Heath,S.C., Hercberg,S., Hillman,D.R., Hingorani,A.D., Hui,J.,
            Hung,J., Kaakinen,M., Kaprio,J., Kesaniemi,Y.A., Kivimaki,M.,
            Knight,B., Koskinen,S., Kovacs,P., Kyvik,K.O., Lathrop,G.M.,
            Lawlor,D.A., Le Bacquer,O., Lecoeur,C., Li,Y., Mahley,R.,
            Mangino,M., Martinez-Larrad,M.T., McAteer,J.B., McPherson,R.,
            Meisinger,C., Melzer,D., Meyre,D., Mitchell,B.D., Mukherjee,S.,
            Naitza,S., Neville,M.J., Orru,M., Pakyz,R., Paolisso,G.,
            Pattaro,C., Pearson,D., Peden,J.F., Pedersen,N.L., Pfeiffer,A.F.,
            Pichler,I., Polasek,O., Posthuma,D., Potter,S.C., Pouta,A.,
            Province,M.A., Rayner,N.W., Rice,K., Ripatti,S., Rivadeneira,F.,
            Rolandsson,O., Sandbaek,A., Sandhu,M., Sanna,S., Sayer,A.A.,
            Scheet,P., Seedorf,U., Sharp,S.J., Shields,B., Sigurethsson,G.,
            Sijbrands,E.J., Silveira,A., Simpson,L., Singleton,A., Smith,N.L.,
            Sovio,U., Swift,A., Syddall,H., Syvanen,A.C., Tonjes,A.,
            Uitterlinden,A.G., van Dijk,K.W., Varma,D., Visvikis-Siest,S.,
            Vitart,V., Vogelzangs,N., Waeber,G., Wagner,P.J., Walley,A.,
            Ward,K.L., Watkins,H., Wild,S.H., Willemsen,G., Witteman,J.C.,
            Yarnell,J.W., Zelenika,D., Zethelius,B., Zhai,G., Zhao,J.H.,
            Zillikens,M.C., Borecki,I.B., Meneton,P., Magnusson,P.K.,
            Nathan,D.M., Williams,G.H., Silander,K., Bornstein,S.R.,
            Schwarz,P., Spranger,J., Karpe,F., Shuldiner,A.R., Cooper,C.,
            Serrano-Rios,M., Lind,L., Palmer,L.J., Hu,F.B. 1st, Franks,P.W.,
            Ebrahim,S., Marmot,M., Kao,W.H., Pramstaller,P.P., Wright,A.F.,
            Stumvoll,M., Hamsten,A., Buchanan,T.A., Valle,T.T., Rotter,J.I.,
            Penninx,B.W., Boomsma,D.I., Cao,A., Scuteri,A., Schlessinger,D.,
            Uda,M., Ruokonen,A., Jarvelin,M.R., Peltonen,L., Mooser,V.,
            Sladek,R., Musunuru,K., Smith,A.V., Edmondson,A.C., Stylianou,I.M.,
            Koseki,M., Pirruccello,J.P., Chasman,D.I., Johansen,C.T.,
            Fouchier,S.W., Peloso,G.M., Barbalic,M., Ricketts,S.L., Bis,J.C.,
            Feitosa,M.F., Orho-Melander,M., Melander,O., Li,X., Li,M.,
            Cho,Y.S., Go,M.J., Kim,Y.J., Lee,J.Y., Park,T., Kim,K., Sim,X.,
            Ong,R.T., Croteau-Chonka,D.C., Lange,L.A., Smith,J.D., Ziegler,A.,
            Zhang,W., Zee,R.Y., Whitfield,J.B., Thompson,J.R., Surakka,I.,
            Spector,T.D., Smit,J.H., Sinisalo,J., Scott,J., Saharinen,J.,
            Sabatti,C., Rose,L.M., Roberts,R., Rieder,M., Parker,A.N., Pare,G.,
            O'Donnell,C.J., Nieminen,M.S., Nickerson,D.A., Montgomery,G.W.,
            McArdle,W., Masson,D., Martin,N.G., Marroni,F., Lucas,G., Luben,R.,
            Lokki,M.L., Lettre,G., Launer,L.J., Lakatta,E.G., Laaksonen,R.,
            Kyvik,K.O., Konig,I.R., Khaw,K.T., Kaplan,L.M., Johansson,A.,
            Janssens,A.C., Igl,W., Hovingh,G.K., Hengstenberg,C.,
            Havulinna,A.S., Hastie,N.D., Harris,T.B., Haritunians,T.,
            Hall,A.S., Groop,L.C., Gonzalez,E., Freimer,N.B., Erdmann,J.,
            Ejebe,K.G., Doring,A., Dominiczak,A.F., Demissie,S., Deloukas,P.,
            de Faire,U., Crawford,G., Chen,Y.D., Caulfield,M.J.,
            Boekholdt,S.M., Assimes,T.L., Quertermous,T., Seielstad,M.,
            Wong,T.Y., Tai,E.S., Feranil,A.B., Kuzawa,C.W., Taylor,H.A. Jr.,
            Gabriel,S.B., Holm,H., Gudnason,V., Krauss,R.M., Ordovas,J.M.,
            Munroe,P.B., Kooner,J.S., Tall,A.R., Hegele,R.A., Kastelein,J.J.,
            Schadt,E.E., Strachan,D.P., Reilly,M.P., Samani,N.J., Schunkert,H.,
            Cupples,L.A., Sandhu,M.S., Ridker,P.M., Rader,D.J. and
            Kathiresan,S.
  CONSRTM   DIAGRAM+ Consortium; MAGIC Consortium; GLGC Investigators; MuTHER
            Consortium; DIAGRAM Consortium; GIANT Consortium; Global B Pgen
            Consortium; Procardis Consortium; MAGIC investigators; GLGC
            Consortium
  TITLE     Novel loci for adiponectin levels and their influence on type 2
            diabetes and metabolic traits: a multi-ethnic meta-analysis of
            45,891 individuals
  JOURNAL   PLoS Genet 8 (3), e1002607 (2012)
   PUBMED   22479202
REFERENCE   8  (bases 1 to 14039)
  AUTHORS   Chasman,D.I., Pare,G., Mora,S., Hopewell,J.C., Peloso,G.,
            Clarke,R., Cupples,L.A., Hamsten,A., Kathiresan,S., Malarstig,A.,
            Ordovas,J.M., Ripatti,S., Parker,A.N., Miletich,J.P. and
            Ridker,P.M.
  TITLE     Forty-three loci associated with plasma lipoprotein size,
            concentration, and cholesterol content in genome-wide analysis
  JOURNAL   PLoS Genet 5 (11), e1000730 (2009)
   PUBMED   19936222
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   9  (bases 1 to 14039)
  AUTHORS   Pazour,G.J., Agrin,N., Walker,B.L. and Witman,G.B.
  TITLE     Identification of predicted human outer dynein arm genes:
            candidates for primary ciliary dyskinesia genes
  JOURNAL   J Med Genet 43 (1), 62-73 (2006)
   PUBMED   15937072
REFERENCE   10 (bases 1 to 14039)
  AUTHORS   Maiti,A.K., Mattei,M.G., Jorissen,M., Volz,A., Zeigler,A. and
            Bouvagnet,P.
  TITLE     Identification, tissue specific expression, and chromosomal
            localisation of several human dynein heavy chain genes
  JOURNAL   Eur J Hum Genet 8 (12), 923-932 (2000)
   PUBMED   11175280
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            HY041008.1, DV080259.1, AC117503.8, BC144575.1, AK125475.1,
            DV080609.1, AB290168.1, AC079315.30 and AI333321.1.
            
            Summary: Dyneins are microtubule-associated motor protein complexes
            composed of several heavy, light, and intermediate chains. The
            axonemal dyneins, found in cilia and flagella, are components of
            the outer and inner dynein arms attached to the peripheral
            microtubule doublets. DNAH10 is an inner arm dynein heavy chain
            (Maiti et al., 2000 [PubMed 11175280]).[supplied by OMIM, Mar
            2008].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148874 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000673944.1/ ENSP00000501095.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, expression, longest
                                         protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-324               HY041008.1         70-393
            325-717             DV080259.1         118-510
            718-877             AC117503.8         45210-45369         c
            878-1035            AC117503.8         43245-43402         c
            1036-1351           BC144575.1         332-647
            1352-1656           AK125475.1         672-976
            1657-1661           AC117503.8         36578-36582         c
            1662-1851           AK125475.1         982-1171
            1852-2022           AC117503.8         32397-32567         c
            2023-3657           AK125475.1         1172-2806
            3658-3816           AK125475.1         2920-3078
            3817-4010           DV080609.1         226-419
            4011-5173           AB290168.1         165-1327
            5174-5281           AC079315.30        16819-16926
            5282-14038          AB290168.1         1436-10192
            14039-14039         AI333321.1         87-87
FEATURES             Location/Qualifiers
     source          1..14039
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q24.31"
     gene            1..14039
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /note="dynein axonemal heavy chain 10"
                     /db_xref="GeneID:196385"
                     /db_xref="HGNC:HGNC:2941"
                     /db_xref="MIM:605884"
     exon            1..250
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..13806
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /note="isoform 3 is encoded by transcript variant 3;
                     dynein, axonemal, heavy polypeptide 10; dynein heavy chain
                     10, axonemal; ciliary dynein heavy chain 10; axonemal beta
                     dynein heavy chain 10"
                     /codon_start=1
                     /product="dynein axonemal heavy chain 10 isoform 3"
                     /protein_id="NP_001359035.1"
                     /db_xref="CCDS:CCDS91767.1"
                     /db_xref="GeneID:196385"
                     /db_xref="HGNC:HGNC:2941"
                     /db_xref="MIM:605884"
                     /translation="MDDLRVLWMRDRVYAAFGITDPQLFEDLLNRDDGQGEDLILHFL
                     NQASEEEGPSALFIYRTMVPEEVEVEIDEIPVLSEEGEEEEETYSQKVESVDKVRAKR
                     VSLRTESLGQPLNREDEEMDKEISEKLPSKRTAKHIMEKMHLHMLCTPLPEEFLDQNV
                     VFFLRNTKEAISEATDMKEAMEIMPETLEYGIINANVLHFLKNIICQVFLPALSFNQH
                     RTSTTVGVTSGEVSNSSEHESDLPPMPGEAVEYHSIQLIRDEFLMNVQKFASNIQRTM
                     QQLEGEIKLEMPIISVEGEVSDLAADPETVDILEQCVINWLNQISTAVEAQLKKTPQG
                     KGPLAEIEFWRERNATLSALHEQTKLPIVRKVLDVIKESDSMLVANLQPVFTELFKFH
                     TEASDNVRFLSTVERYFKNITHGSGFHVVLDTIPAMMSALRMVWIISRHYNKDERMIP
                     LMERIAWEIAERVCRVVNLRTLFKENRASAQSKTLEARNTLRLWKKAYFDTRAKIEAS
                     GREDRWEFDRKRLFERTDYMATICQDLSDVLQILEEFYNIFGPELKAVTGDPKRIDDV
                     LCRVDGLVTPMENLTFDPFSIKSSQFWKYVMDEFKIEVLVIEKEAKHFIDESFKTLRS
                     AEAAFDMLLKFKHIRSREAVNRQMMMKFNDILAQYCKEIDIINKIFVQNLENPPLYKN
                     HPPVAGAIYWERSLFFRIKHTILRFQEVQEILDSDRGQEVKQKYLEVGRTMKEYEDRK
                     YEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINETKYL
                     EQLGFTVPELARNVALQEDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQELL
                     RVFRSGYKRLNWNSLGIGDYITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAINLF
                     KYPAAKSEEELPGVKEFFEHIERERASDVDHMVRWYLAIGPLLTKVEGLVVHTNTGKA
                     PKLASYYKYWEKKIYEVLTKLILKNLQSFNSLILGNVPLFHTETILTAPEIILHPNTN
                     EIDKMCFHCVRNCVEITKHFVRWMNGSCIECPPQKGEEEEVVIINFYNDISLNPQIIE
                     QAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAAKKPPCVAYDEKLQFY
                     SKIAYEVMRHPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHE
                     EMEHLAKNLRKIPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPP
                     DAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFY
                     SEGPGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKE
                     MSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVT
                     YYLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELH
                     KHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERGYILGSVDEII
                     QSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFI
                     GGDIRSQLPEEAKKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKC
                     QKSLNDYLDSKRNAFPRFFFISDDELLSILGSSDPLCVQEHMIKMYDNIASLRFNDGD
                     SGEKLVSAMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCED
                     RSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVT
                     RITMPLSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDE
                     LNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTE
                     TTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVIS
                     SQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVV
                     VIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKSVLV
                     MAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPD
                     FNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQ
                     TKLGLTTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREINKPTDKKERKYIL
                     FDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCG
                     MVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQAEK
                     LKTIVPQTDLNMVTQLAKMLDALLEGEIEDLDLLECYFLEALYCSLGASLLEDGRMKF
                     DEYIKRLASLSTVDTEGVWANPGELPGQLPTLYDFHFDNKRNQWVPWSKLVPEYIHAP
                     ERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSKTATTQNFLKNLSEETNI
                     VLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVFMDDMNMPRVDEYGTQQ
                     PIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNEVDPRFISLFSVFNV
                     PFPSEESLHLIYSSILKGHTSTFHESIVAVSGKLTFCTLALYKNIVQDLPPTPSKFHY
                     IFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISETDKQLVQQHIG
                     SLVVEHFKDDVEVVMRDPILFGDFQMALHEGEPRIYEDIQDYEAAKALFQEILEEYNE
                     SNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAFTASCEVFE
                     ILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTSGIVP
                     ALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIVLGMSPVGDTLRT
                     WCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKHVVLVHQSV
                     DHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEAT
                     IQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKV
                     IAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMK
                     GYKELNWKTAKGVMSDPNFLRSLMEIDFDSITQSQVKNIKGLLKTLNTTTEEMEAVSK
                     AGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELE
                     TLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKL
                     LGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDILEREIPLSQPFRLESLLTDDVEIS
                     RWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPD
                     FLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNF
                     RLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQ
                     ETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEKTA
                     LDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSIL
                     MKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGN
                     ISLEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLE
                     QFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFE
                     QSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRLKFLAMGQGQEKVALQLLETAVA
                     RGQWLMLQNCHLLVKWLKDLEKSLERITKPHPDFRLWLTTDPTKGFPIGILQKSLKVV
                     TEPPNGLKLNMRATYFKISHEMLDQCPHPAFKPLVYVLAFFHAVVQERRKFGKIGWNV
                     YYDFNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRIL
                     TIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGL
                     HPNAEIGYYTQAARDMWAHLLELQPQTGESSSGISRDDYIGQVAKEIENKMPKVFDLD
                     QVRKRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARS
                     LFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTESEPSVMWLSGLHIPESY
                     LTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEK
                     GCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAMGVGLVFEADL
                     FTTRHISHWVLQGVCLTLNSD"
     exon            251..334
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            335..432
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            433..541
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            542..657
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            658..877
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            878..1035
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1266
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            1267..1457
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..1656
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            1657..1851
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            1852..2022
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            2023..2199
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            2200..2325
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            2326..2498
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            2499..2650
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            2651..2815
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            2816..3023
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            3024..3180
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            3181..3657
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            3658..3816
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            3817..3933
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            3934..4036
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            4037..4215
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            4216..4427
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            4428..4581
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            4582..4815
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            4816..4938
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            4939..5172
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            5173..5396
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            5397..5666
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            5667..5850
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            5851..5985
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            5986..6138
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            6139..6327
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            6328..6474
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            6475..6666
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            6667..6785
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            6786..6944
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            6945..7080
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            7081..7203
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            7204..7338
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            7339..7555
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            7556..7675
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            7676..7821
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            7822..7974
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            7975..8235
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            8236..8408
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            8409..8502
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            8503..8670
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            8671..8859
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            8860..9031
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            9032..9235
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            9236..9316
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            9317..9514
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            9515..9676
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            9677..9851
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            9852..10033
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            10034..10170
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            10171..10388
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            10389..10610
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            10611..10758
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            10759..11038
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            11039..11268
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            11269..11542
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            11543..11647
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            11648..11802
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            11803..11957
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            11958..12141
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            12142..12342
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            12343..12552
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            12553..12648
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            12649..12820
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            12821..12952
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            12953..13164
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            13165..13332
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            13333..13513
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            13514..13659
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     exon            13660..14039
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /inference="alignment:Splign:2.1.0"
     regulatory      14022..14027
                     /regulatory_class="polyA_signal_sequence"
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /note="hexamer: AGTAAA"
     polyA_site      14039
                     /gene="DNAH10"
                     /gene_synonym="SPGF56"
                     /note="major polyA site"
ORIGIN      
        1 gccctgcgcc cggctccctc tgcactgcgc ggcgccatgg acgacctgcg ggtgctgtgg
       61 atgcgcgacc gcgtgtatgc ggctttcggc atcaccgacc cccagctttt cgaggacctg
      121 ctcaaccgcg acgacggcca gggcgaggac ctcatcttgc acttcctcaa ccaggcgagc
      181 gaggaggagg ggccctcggc gctcttcatc taccgcacta tggtgccgga ggaggtggag
      241 gtggagattg atgagatacc tgtcctgtct gaagagggag aagaggaaga agagacttat
      301 tctcaaaaag tggagtccgt ggataaagtg cgagctaagc gtgtgtcact gagaaccgaa
      361 tctctaggcc aacctctaaa cagagaggat gaagaaatgg acaaagagat ttcagaaaaa
      421 ctcccttcca aaagaactgc gaagcacatc atggaaaaga tgcatctcca catgctctgt
      481 acccctcttc ccgaggagtt cctggaccaa aacgtggtgt ttttcctcag aaataccaaa
      541 gaggcaatct ctgaagctac cgacatgaag gaagctatgg aaattatgcc agaaacactg
      601 gagtatggaa ttataaacgc taatgtgctc cattttctga agaatattat atgtcaggtt
      661 tttttgccag cattgtcctt caatcagcac aggacgagta caaccgtggg agtcacatct
      721 ggagaagtct ctaattcctc tgagcatgaa tcagacctgc cgcccatgcc tggggaggca
      781 gtagaatatc acagtattca attaatacgg gatgaatttt taatgaacgt gcagaaattt
      841 gcaagtaata ttcaaagaac catgcagcaa cttgaaggtg agatcaagtt agaaatgcca
      901 atcatcagtg tggagggaga ggtgtctgac ctggcagctg acccggaaac cgttgacatc
      961 ttggagcagt gtgtgataaa ctggctgaat cagatatcca cagcggttga ggcccaactg
     1021 aagaagacac ctcagggtaa aggccctctg gctgaaattg aattctggag ggaaagaaat
     1081 gcaaccttaa gtgcgctgca tgaacaaaca aagcttccaa tagtcagaaa agtcttggat
     1141 gtgatcaagg aatccgactc catgcttgtg gctaatctgc agccagtgtt caccgagtta
     1201 ttcaagttcc acacggaggc ctcagacaat gtgcgctttc tctccaccgt ggagcgttat
     1261 ttcaagaaca taacgcacgg gtctggcttc cacgtggtcc tggacaccat ccccgccatg
     1321 atgagtgccc tgcggatggt gtggatcatc tcccgacact acaacaaaga cgagaggatg
     1381 attccgctca tggagcgcat cgcctgggaa atcgctgaga gagtctgccg agtggtcaac
     1441 ctgcggactt tgttcaaaga aaatcgagcg agtgcccaaa gcaaaacctt ggaagccagg
     1501 aacaccctca ggctgtggaa aaaggcctat tttgacaccc gggccaagat agaggcttcg
     1561 gggagggaag atcggtggga gtttgaccgg aagcggctgt tcgagaggac ggattatatg
     1621 gccaccatct gccaggacct ctccgacgtt ctgcagattt tggaggaatt ttataacata
     1681 tttggtccag aactaaaggc agtgacgggg gaccccaagc gcattgatga tgtcctatgc
     1741 agagtggacg gcctagtcac ccccatggaa aacctgacct ttgacccctt cagcatcaag
     1801 tcctcccagt tctggaaata tgtgatggat gaattcaaga ttgaagttct ggttattgag
     1861 aaagaagcaa aacattttat tgatgaatct tttaagacgc ttcgatctgc tgaagcagca
     1921 tttgacatgc ttttaaaatt taagcacatt cgttcacggg aggctgttaa tcgacaaatg
     1981 atgatgaaat ttaatgatat tcttgcacag tactgtaaag agattgacat cattaataaa
     2041 atctttgtcc agaaccttga aaatccacca ctgtataaga atcaccctcc agtagcaggt
     2101 gcaatatact gggaacgatc tctgttcttt cggattaagc ataccatcct ccgatttcaa
     2161 gaggtacaag agatactgga cagtgatcga ggacaggagg tcaaacaaaa atatttggaa
     2221 gtaggtagga caatgaagga gtatgaagac agaaagtatg agcagtggat ggaggtgacg
     2281 gagcaggtgc tgccagctct catgaagaag agccttttga ccaagtcttc catcgccaca
     2341 gaggagcctt cgactttaga aaggggagct gtttttgcaa tcaacttttc accggctctc
     2401 agagagatta ttaatgaaac aaagtactta gagcagctgg ggttcactgt ccctgaatta
     2461 gcaagaaatg ttgctctcca ggaagacaaa ttccttaggt acacagctgg gatacagcgc
     2521 atgttggatc attatcacat gctcatagga acgttaaacg atgcggagtc tgtgcttctc
     2581 aaagatcatt cccaggaact gctccgagtg tttaggtcgg gatataagag gttgaactgg
     2641 aactcactag gtatcggtga ctatataact ggttgcaaac aggccattgg gaaatttgag
     2701 tctctcgtcc accagattca taagaatgca gatgacattt cttccaggct gacattaata
     2761 gaggccataa atctctttaa atatccagcc gctaaaagtg aggaagaact cccaggcgtg
     2821 aaggaatttt ttgaacacat tgagcgagaa agggccagcg acgtggacca catggtccgg
     2881 tggtatcttg ccattggacc actgctgacc aaagttgagg gcctggtcgt ccacaccaac
     2941 acaggcaagg cccccaagct ggcctcctac tacaaatact gggaaaagaa aatttatgag
     3001 gtcctgacaa agctcatcct gaagaacttg cagtctttta attctttgat ccttggaaat
     3061 gtccctctgt tccacactga aaccattctg acggcacctg agatcatcct tcatcccaac
     3121 acaaatgaga tcgacaagat gtgcttccat tgtgtccgga attgcgtgga gatcaccaag
     3181 cattttgttc gttggatgaa tggcagctgc atagaatgcc cacctcagaa gggggaggaa
     3241 gaggaagttg ttataataaa cttttacaat gatatctctc tgaaccctca gataattgaa
     3301 caagctgtta tgatccccca aaatgtccac aggattctga tcaatcttat gaagtatcta
     3361 caaaaatgga agcggtatcg acctctctgg aaattggaca aagctattgt gatggagaaa
     3421 tttgctgcca agaaacctcc ttgtgtagca tatgatgaaa agttgcagtt ctattccaag
     3481 atagcttatg aggttatgcg ccaccctcta attaaggatg agcattgcat cagacttcag
     3541 ctcaggcatc tggcaaacac agtgcaggaa aatgccaagt cctgggtgat ttcgcttgga
     3601 aaacttctca atgagtcagc aaaagaggag ctctataatc tccatgaaga gatggagcac
     3661 ctggccaaaa accttaggaa gatccccaat acccttgaag atctcaagtt tgtccttgca
     3721 acaattgcag aaattagaag taaatctcta gtcatggaac tcagatatag ggacgtccag
     3781 gagcgatacc gtaccatggc aatgtataac ctctttcctc ctgatgcaga gaaagaactg
     3841 gttgataaga ttgagagcat atggtccaat ctgtttaatg attcagtgaa tgtggagcat
     3901 gctcttgggg acataaagag aactttcaca gagcttactc gaggcgaaat aatgaactac
     3961 agagttcaga tagaggagtt tgcaaagcgt ttttacagtg aaggccctgg ttctgttggt
     4021 gatgatcttg ataaaggagt agagctttta ggtgtttatg aaagagagct ggcaagacat
     4081 gaaaagagcc gtcaggaact ggctaacgct gagaaacttt tcgatcttcc tattacaatg
     4141 tacccagagc tgctgaaagt gcagaaggaa atgagtgggc tgaggatgat ttacgagctc
     4201 tatgaaggac taaaggttgc aaaagaagaa tggtctcaga ccctttggat caacctgaat
     4261 gtgcagattc tccaggaagg aattgaaggt tttctcaggg ctctcagaaa gctacctcgg
     4321 ccagtccgtg gcttatcagt gacctactac ttggaagcaa aaatgaaggc attcaaagac
     4381 tcgattcctt tacttcttga cttgaaaaac gaggcactaa gagacaggca ttggaaagaa
     4441 cttatggaaa aaacgtctgt cttttttgaa atgaccgaaa cgttcacctt ggaaaatatg
     4501 tttgctatgg aactgcacaa acacacagat gttctcaatg agattgtcac agcagcaatc
     4561 aaggaggttg ccattgagaa ggctgtgaag gaaatcctag acacgtggga aaatatgaaa
     4621 ttcactgtag tcaagtattg caaaggcaca caggagcgag gctacatcct gggttctgtt
     4681 gacgaaatta ttcagtctct tgatgacaac actttcaacc tgcagagcat ctcaggaagc
     4741 agatttgtgg ggccttttct gcaaactgtt cacaaatggg aaaaaacgct ttctctaata
     4801 ggggaagtca ttgagatttg gatgttggtt cagagaaaat ggatgtatct tgaaagtatt
     4861 tttattggtg gagatataag atcacaactt ccggaagagg caaaaaagtt tgacaacatc
     4921 gataaagtat ttaaaaggat catgggtgag accttaaaag accccgtgat caagaggtgc
     4981 tgtgaagccc caaaccgcct cagtgaccta cagaacgtca gcgagggcct ggagaaatgc
     5041 cagaaaagcc tcaacgacta cttagattcg aagagaaatg ctttcccaag gttcttcttc
     5101 atttctgacg atgagttgct tagcattctg gggagcagcg acccactctg cgtccaggag
     5161 cacatgatca agatgtacga caacatagca tcactgaggt ttaatgacgg cgatagtgga
     5221 gaaaaactgg tgtccgcgat gatttcagca gaaggagaag tcatggagtt tcggaagatc
     5281 ttgcgggctg aagggcgcgt ggaggactgg atgacggcag ttttgaatga gatgagaaga
     5341 actaatagac taattaccaa agaggctatt tttagatact gtgaagacag aagcagagtc
     5401 gactggatgc tcctgtacca gggcatggtg gtgctggccg ctagccaggt gtggtggacc
     5461 tgggaggtgg aagacgtctt ccacaaagcg caaaaagggg agaagcaggc catgaagaac
     5521 tatggcagga aaatgcaccg gcagatcgat gagttggtaa cgcgcatcac catgccgcta
     5581 agcaaaaacg acaggaaaaa atacaacact gttctcatca ttgatgtgca tgccagagac
     5641 atagttgatt ctttcataag aggcagtatc ctggaggccc gagagtttga ctgggaaagt
     5701 cagttgcggt tttattggga ccgggagccg gatgagctga acatccgcca gtgcacggga
     5761 acctttggct acggctacga gtacatgggc ctgaacggca ggctggtcat cacgcccctc
     5821 accgatcgga tttacctgac gctcacccag gcgctgtcca tgtatctagg tggggccccc
     5881 gccggcccag caggaaccgg caaaaccgag accaccaagg acctggcgaa agccttgggc
     5941 ttgctctgtg ttgtcaccaa ctgtggcgaa ggcatggatt acagggccgt ggggaagatt
     6001 ttctctggcc tggcacagtg cggggcttgg ggctgctttg atgagtttaa tcgaatcgat
     6061 gcttctgtgc tctccgtgat ctcctcccag atccagacga tccgaaatgc tctgatccat
     6121 cagttaacca cgttccagtt tgaagggcag gagatttccc tggactcccg catgggcatc
     6181 ttcatcacca tgaaccccgg ctacgcaggc cgcacggagc tgcccgagtc ggtgaaggcg
     6241 ctgttcaggc ctgtggtcgt gatcgtgccc gacctgcagc agatctgtga gatcatgctc
     6301 ttctctgagg gcttcctgga ggccaagact ctggcgaaaa agatgacggt tctgtataag
     6361 ctggcccggg agcagctgtc caagcagtat cactatgatt ttggactcag agccctgaaa
     6421 tcggtgctgg tcatggctgg tgagctgaag agaggctcct ctgaccttag ggaggacgtg
     6481 gtgctgatga gggccttgcg agacatgaac ttgcccaaat ttgtgtttga agatgttcct
     6541 cttttccttg gtttgatttc ggatctgttt cctgggctgg actgccctcg cgtccgctac
     6601 cctgacttca acgatgcggt agagcaggtc ctggaggaga acggctacgc ggtcctaccc
     6661 atccaggtgg ataaagtggt tcaaatgttc gagaccatgt taacccgcca cacgacgatg
     6721 gtggtggggc ccaccagagg gggcaagtcc gtcgtcatta acactctgtg tcaggcccag
     6781 accaagcttg ggctgacgac aaagttgtac atcctgaacc ccaaagccgt gagtgtcata
     6841 gaactctacg gcatcctgga cccaaccacc cgagactgga cagatggggt gttgtcaaac
     6901 atcttcaggg aaatcaacaa gccaacagac aagaaggagc gaaagtatat tttatttgat
     6961 ggtgatgtgg atgctctatg ggtggaaaac atgaattctg tgatggatga caacaggttg
     7021 ttgacattgg ccaacgggga acgcatccgg ctccaagcac actgtgccct gctctttgag
     7081 gttggagatt tacagtatgc ctcccctgca actgtctctc gatgtggaat ggtttatgtg
     7141 gatcctaaaa acttgaaata tcgaccatac tggaaaaaat gggttaatca aataccaaac
     7201 aaggtggagc aatacaattt gaatagtctc tttgagaagt atgtgcccta tctcatggat
     7261 gtgatagtgg aaggaattgt ggatggaaga caagcagaaa agctgaagac aatagttcct
     7321 cagacagacc tcaatatggt aacccagtta gccaagatgt tggatgcgtt gctagaagga
     7381 gaaatagaag accttgacct gctggagtgc tacttcctgg aggctttgta ctgctctctg
     7441 ggagcctccc tgcttgagga tggaaggatg aaatttgacg aatatatcaa acgccttgct
     7501 tctttgtcta ctgttgacac agaaggagtt tgggccaacc ctggggaact gccaggtcaa
     7561 cttccaacct tgtatgactt tcattttgat aacaaacgga atcaatgggt cccatggagt
     7621 aaattagttc cagagtatat tcatgccccc gagaggaaat tcatcaacat cctggttcac
     7681 acagtggata ccactcggac tacctggata ttggaacaaa tggttaaaat taagcaacct
     7741 gttatttttg ttggtgaatc tggcacttct aagacagcca ctacccagaa tttcctcaaa
     7801 aatctgagtg aagaaactaa cattgtgtta atggtcaact tctcctcccg caccacgtcc
     7861 atggatatcc aaagaaattt agaagcaaat gtggaaaagc gaaccaaaga tacttacggc
     7921 ccacccatgg gaaaacgcct gctggtgttc atggatgaca tgaatatgcc aagggtggat
     7981 gaatatggca cgcagcagcc cattgccttg ctgaagctgc tgttggaaaa aggctactta
     8041 tatgaccgtg ggaaggagct gaactgtaaa agcattcgag accttggctt tattgctgca
     8101 atgggaaagg ctggaggagg ccgcaatgaa gttgacccaa gatttatttc gctattcagt
     8161 gtcttcaatg tgccatttcc ttcagaggag tctctgcatt taatttattc ctccatcctg
     8221 aaaggccaca cctcgacgtt tcatgagagc attgtggctg tgagtggcaa gctgacattc
     8281 tgcacgctag cactttacaa aaatattgtg caagacctac ctcccactcc gtcaaagttc
     8341 cattacatct tcaaccttcg agatctctca cgggttttta atggtcttgt cctcactaac
     8401 ccggagcgat tccagacggt ggcccagatg gtgagagtct ggaggaatga gtgtctgaga
     8461 gtcttccacg accggctgat cagtgaaaca gacaagcagc tggtacaaca gcacataggc
     8521 agcttggttg tggaacattt taaagatgac gtggaggtgg tgatgaggga tcccatattg
     8581 tttggagact tccagatggc tctgcacgaa ggagaaccac gcatttatga agacatccag
     8641 gactacgagg cggccaaggc tctgttccag gaaattcttg aagagtataa tgaaagcaac
     8701 accaaaatga acttggttct cttcgacgat gctctggagc atttaacccg ggtgcaccgt
     8761 atcatccgca tggaccgcgg ccacgccctg ctggtcgggg tagggggctc agggaagcag
     8821 tctctttcga ggctggctgc cttcacagcc agctgtgagg tgtttgagat cctgctgagc
     8881 cgaggctact cggagaacag tttccgggaa gacctgaaga gcctctattt gaaacttggg
     8941 attgagaaca aagcgatgat ctttctgttc acggatgccc atgtggctga ggagggcttc
     9001 ctggagctca tcaacaacat gctgacctca ggaattgtac ctgcgctttt ttctgaagag
     9061 gagaaagagt ctatcctgag tcagattgga caggaagctc tgaagcaagg catggggccg
     9121 gccaaggagt ctgtgtggca gtacttcgtg aacaaaagtg caaataacct gcacattgtc
     9181 ctgggcatgt cgccagtggg ggacaccctg aggacctggt gcagaaactt cccaggtatg
     9241 gtaaataaca ctggtattga ctggttcatg ccctggcctc cccaagccct ccatgcggtc
     9301 gcaaagtcct ttctagggta taatccaatg atcccggcag aaaatataga aaatgtggtg
     9361 aagcatgttg tcttggttca ccaatccgtg gaccactaca gccaacagtt tctacagaaa
     9421 ttgaggcgca gcaactatgt cactcccaag aactaccttg attttattaa cacctattca
     9481 aaattgctgg atgagaaaac tcagtgtaat atagctcagt gcaagcgtct ggatggggga
     9541 ctggacaagc tgaaggaggc caccatccag ctggacgagc tgaaccagaa gctggccgag
     9601 cagaagatcg tgctggcgga gaagtccgcc gcctgcgagg ccttgctgga ggagatcgcc
     9661 gtcaacaccg ctgtagccga ggagaagaag aaactggcag aggaaaaggc catggagata
     9721 gaggagcaga acaaagtcat tgccatggag aaggccgagg ccgagacgac cctggcagag
     9781 gtcatgccca tcctggaggc cgccaagctg gaactgcaga agctggacaa gtcggacgtg
     9841 actgagatta ggtcgtttgc taagcccccg aagcaggtgc agacggtctg cgaatgcatc
     9901 ctcatcatga aagggtacaa agagctgaac tggaaaacag ccaagggcgt gatgtccgac
     9961 ccgaatttcc tgcggtctct gatggagatt gattttgatt cgattaccca gagccaagtg
    10021 aaaaacatca aaggcctctt gaagactctt aataccacaa ctgaagaaat ggaagctgtc
    10081 agcaaagccg ggctggggat gctgaaattt gttgaagctg taatgggcta ctgtgatgtt
    10141 ttcagagaaa tcaagcccaa aagagagaag gtggccaggc tggagcggaa tttttacctc
    10201 actaaacggg aactggaaag gatccagaat gagttggcag caattcagaa agagctggaa
    10261 acattgggtg ccaaatatga ggccgccata ctggaaaagc agaagctgca ggaagaagcc
    10321 gagatcatgg agaggcggct gattgccgca gacaaactca tctcgggtct ggggtcagaa
    10381 aacatcaggt ggctgaacga cctggatgag ctgatgcacc ggcgcgtgaa gctgctgggg
    10441 gactgcctgc tctgcgcggc tttcctcagc tacgagggag ccttcacctg ggagttccgt
    10501 gacgagatgg tcaatcggat ttggcaaaat gacatcctgg agcgggagat ccccctgagc
    10561 cagcctttcc ggctggaaag cctgctcacg gatgatgttg agatcagcag atggggatcc
    10621 cagggccttc cccccgatga gctctccgtt cagaatggca tcctcaccac ccgggccagc
    10681 cgcttccctc tgtgtatcga cccccagcag caggccctca actggatcaa gagaaaagag
    10741 gagaagaaca atctgcgggt cgcttccttt aatgaccctg acttcctcaa gcagctagag
    10801 atgtccataa agtacgggac ccctttcctg ttccgcgatg ttgatgaata catcgatcct
    10861 gtgattgaca acgtcttaga aaaaaatata aaagtctccc aaggacggca gtttattatc
    10921 ctgggagaca aggaagtgga ctatgattca aatttcagac tgtacctgaa caccaagctg
    10981 gccaatccca gatattcccc atccgtgttt gggaaagcta tggtgatcaa ttacactgtc
    11041 acgctgaagg gcctggagga ccagctgctg agcgtgctgg tggcttacga gaggcgggag
    11101 ctggaggagc agcgggagca cctcatccag gagaccagcg agaacaagaa cctgctcaag
    11161 gacctggaag attccctcct tcgggagctg gccacgtcca cggggaacat gctggacaat
    11221 gtggacctgg tgcacaccct ggaggagacc aaatccaagg caacagaggt ctcagagaaa
    11281 ctcaagctgg cggagaagac agccttggac atcgacaggc tgcgggatgg ctaccggcca
    11341 gcagccagga ggggggccat cctgttcttc gtcctgtctg agatggccct ggtgaactcc
    11401 atgtaccagt actccctgat tgccttctta gaggtcttca ggctgtcact gaagaagtcg
    11461 ctgcctgatt ccatcctcat gaaacgcctg aggaacatca tggacacgct gaccttcagc
    11521 atctataacc acggctgcac agggctgttt gagaggcaca agctactctt ttcttttaat
    11581 atgaccatca agatagaaca agcagaaggg agagtccctc aagaagaact agatttcttt
    11641 ttaaaaggaa acatttccct ggagaaaagc aaaagaaaaa agccctgcgc ttggttgtct
    11701 gaccaaggat gggaagatat cattctttta tcagaaatgt tttcagacaa ctttgggcaa
    11761 cttcctgatg atgttgagaa taatcagact gtctggcagg agtggtatga cctggattca
    11821 ctggagcagt ttcccgtccc cttgggttac gataacaaca tcaccccttt ccagaagttg
    11881 cttattttgc gctgtttccg tgtggatcgg gtctatcggg ccgtgactga ctatgtgact
    11941 gtaacaatgg gagagaagta tgtgcagccc ccaatgatca gctttgaagc tatttttgag
    12001 cagagcactc cacattcgcc cattgtgttt atcctgagtc ctggctccga ccctgccact
    12061 gatcttatga aattagcaga gcgaagtggt tttggaggaa atcgcctcaa attccttgca
    12121 atgggtcaag gtcaagaaaa ggtggccctg cagctgctgg agacggcggt ggctcggggg
    12181 cagtggctga tgctgcagaa ctgccacctc ctggtcaagt ggctgaaaga tctggagaag
    12241 tccctggaga ggatcaccaa gccccaccca gacttccgcc tgtggctcac cacggacccc
    12301 accaagggct tccccattgg gattctgcag aagtccctaa aggttgtcac cgagccaccc
    12361 aatgggctga aactcaacat gagggcaact tacttcaaga tctctcacga aatgctggac
    12421 cagtgcccgc accctgcctt caagccgctg gtctacgtgc tggcgttctt tcatgctgtg
    12481 gtgcaggaga gaaggaagtt tgggaagatt ggctggaacg tgtactatga cttcaatgag
    12541 tctgacttcc aggtctgcat ggaaattctg aacacgtact taacgaaagc cttccagcaa
    12601 cgggacccaa ggatcccgtg gggcagcctc aagtacctaa ttggagaggt catgtatgga
    12661 ggacgggcca tcgacagctt tgatcgccgc atcctgacca tctacatgga tgagtacctg
    12721 ggggacttca tttttgatac tttccagcca ttccacttct tccggaacaa ggaagtggac
    12781 tacaaaatcc ctgttggtga tgaaaaggag aaatttgttg aagccatcga ggccctcccg
    12841 cttgccaaca cgccagaagt gtttggtctc caccccaacg ctgagattgg ctattacacg
    12901 caggcggctc gagacatgtg ggctcacctg ctggagctgc agcctcagac aggggaatcc
    12961 agcagtggta tcagccgcga tgattatatt ggccaagtgg ccaaagaaat agaaaacaag
    13021 atgcccaaag tctttgactt ggaccaggtg aggaagcgcc tcggaacagg actctccccc
    13081 acttcggtgg tgctcctgca ggaactggaa cgcttcaaca agcttgtggt ccggatgacg
    13141 aagtctctgg ctgaacttca aagggccttg gctggagaag ttggaatgag caatgagtta
    13201 gatgatgtgg ccaggtctct ttttatcggg catatcccta atatctggag aaggcttgct
    13261 cctgacacct taaagtccct tggaaactgg atggtctact tcctgcggcg gttcagccag
    13321 tacatgttgt gggtgaccga gagcgagccc agcgtgatgt ggctctcggg gctgcacatc
    13381 cctgagtcct acctcacggc gctggtgcag gccacctgcc ggaagaacgg ctggccactg
    13441 gaccgctcca ccttgttcac acaagtgacc aagttccagg atgcagatga agtgaatgag
    13501 cgggcgggac aaggatgctt tgtctcagga ctgtacctgg aaggtgctga ctgggatata
    13561 gaaaaaggat gtcttatcaa gagcaaaccc aaggtgctgg ttgtggacct gccgatcctg
    13621 aagatcatcc ccattgaagc ccatcgcctc aagctgcaga atactttccg gacccccgtc
    13681 tacaccacct ccatgagaag gaacgccatg ggagtcggct tggtttttga agctgatctc
    13741 tttaccacga ggcacatttc tcactgggtg ctgcaaggag tatgcctcac cctgaattct
    13801 gattaacctt tgggtgaaga aaactgctta atgaattcgg agcctggggt tgtcagagtg
    13861 atcgggtctg ctgtcatttc ttggggcctc tcaagaggca ggagggggac tgacactgat
    13921 ttttcatttg aaatcagcca cttaaatctc tttccataca aattaacctg aatggttttg
    13981 tttttaatac tactttttaa aaggaattta tataatcaaa aagtaaatat tggagagta
//
